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Tytuł:
Different Models of Chemotherapy Taking Into Account Drug Resistance Stemming from Gene Amplification
Autorzy:
Śmieja, J.
Świerniak, A.
Powiązania:
https://bibliotekanauki.pl/articles/908161.pdf
Data publikacji:
2003
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
medycyna
automatyka
biomedical modelling
infinite dimensional systems
multivariable control
Opis:
This paper presents an analysis of some class of bilinear systems that can be applied to biomedical modelling. It combines models that have been studied separately so far, taking into account both the phenomenon of gene amplification and multidrug chemotherapy in their different aspects. The mathematical description is given by an infinite dimensional state equation with a system matrix whose form allows decomposing the model into two interacting subsystems. While the first one, of a finite dimension, can have any form, the other is infinite dimensional and tridiagonal. A methodology of the analysis of such models, based on system decomposition, is presented. An optimal control problem is defined in the l1 space. In order to derive necessary conditions for optimal control, the model description is transformed into an integro-differential form. Finally, biomedical implications of the obtained results are discussed.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2003, 13, 3; 297-305
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Adaptive compensators for pertrubed positive real infinite-dimensional systems
Autorzy:
Curtain, R. F.
Demetriou, M. A.
Ito, K.
Powiązania:
https://bibliotekanauki.pl/articles/908105.pdf
Data publikacji:
2003
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
automatyka
robotyka
infinite dimensional systems
positive real systems
adaptive controllers
Opis:
The aim of this investigation is to construct an adaptive observer and an adaptive compensator for a class of infinite-dimensional plants having a known exogenous input and a structured perturbation with an unknown constant parameter, such as the case of static output feedback with an unknown gain. The adaptive observer uses the nominal dynamics of the unperturbed plant and an adaptation law based on the Lyapunov redesign method. We obtain conditions on the system to ensure uniform boundedness of the estimator dynamics and the parameter estimates, and the convergence of the estimator error. For the case of a known periodic exogenous input we design an adaptive compensator which forces the system to converge to a unique periodic solution. We illustrate our approach with a delay example and a diffusion example for which we obtain convincing numerical results.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2003, 13, 4; 441-452
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The lq-controller synthesis problem for infinite-dimensional systems in factor form
Autorzy:
Grabowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/254801.pdf
Data publikacji:
2013
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
control of infinite-dimensional systems
semigroups
infinite-time lq-control problem
Opis:
The general lq-problem with infinite time horizon for well-posed infinite-dimensional systems has been investigated by George Weiss and Martin Weiss and by Olof Staffans with a complement by Kalle Mikkola and Olof Staffans. Our aim in this paper is to present a solution of a general lq-optimal controller synthesis problem for infinite-dimensional systems in factor form. The systems in factor form are an alternative to additive models, used in the theory of well-posed systems, which rely on leading the analysis exclusively within the basic state space. As a result of applying the simplified analysis in terms of the factor systems and an another derivation technique, we obtain an equivalent, however, astonishingly not the same formulae expressing the optimal controller in the time-domain and the method of spectral factorization. The results are illustrated by two examples of the construction of both the optimal control and optimal controller for some standard lq-problems met in literature: a control problem for a class of boundary controlled hyperbolic equations initiated by Chapelon and Xu, to which we give full solution and an example of the synthesis of the optimal control/controller for the standard lq-problem with infinite-time horizon met in the problem of improving a river water quality by artificial aeration, proposed by Zołopa and the author.
Źródło:
Opuscula Mathematica; 2013, 33, 1; 29-79
1232-9274
2300-6919
Pojawia się w:
Opuscula Mathematica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A non integer order, state space model for one dimensional heat transfer proces
Autorzy:
Oprzedkiewicz, K.
Gawin, E.
Powiązania:
https://bibliotekanauki.pl/articles/229619.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
non-integer order systems
heat transfer process
diffusion equation
infinite dimensional systems
Opis:
In the paper a new, state space, non integer order model for one dimensional heat transfer process is presented. The model is based on known semigroup model. The derivative with respect to time is described by the non integer order Caputo operator, the spatial derivative is described by integer order operator. The elementary properties of the state operator are proven. The solution of state equation is calculated with the use of Laplace transform. Results of experiments show, that the proposed model is more accurate than analogical integer order model in the sense of square cost function.
Źródło:
Archives of Control Sciences; 2016, 26, 2; 261-275
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison between two approaches to modeling microsatellite DNA repeats: infinite dimensional model and its n-dimensional
Autorzy:
Białka, M.
Powiązania:
https://bibliotekanauki.pl/articles/229939.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
infinite-dimensional systems
asymptotic stability
chain systems
microsatellites DNA repeats
polymerase slippage
Opis:
Two approaches to modeling microsatellite DNA repeats are considered. The former is an infinite dimensional system based on the theory of branching random walks which dynamic properties are characterized using Laplace transforms and Laplace asymptotic techniques. The latter is an n-dimensional approximation where microsatellite DNA repeats model is the example of a chain system. Both models were the subject of many numerical calculations using the MATLAB software. The results allow us to evaluate the asymptotic behavior and determine the effect of the system parameters on the run of the solution and the state variables.
Źródło:
Archives of Control Sciences; 2011, 21, 4; 419-441
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The LQ/KYP problem for infinite-dimensional systems
Autorzy:
Grabowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/255449.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
control of infinite-dimensional systems
semigroups
infinite-time LQ-control problem
Lur’e feedback systems
Opis:
Our aim is to present a solution to a general linear-quadratic (LQ) problem as well as to a Kalman-Yacubovich-Popov (KYP) problem for infinite-dimensional systems with bounded operators. The results are then applied, via the reciprocal system approach, to the question of solvability of some Lur'e resolving equations arising in the stability theory of infinite-dimensional systems in factor form with unbounded control and observation operators. To be more precise the Lur’e resolving equations determine a Lyapunov functional candidate for some closed-loop feedback systems on the base of some properties of an uncontrolled (open-loop) system. Our results are illustrated in details by an example of a temperature of a rod stabilization automatic control system.
Źródło:
Opuscula Mathematica; 2017, 37, 1; 21-64
1232-9274
2300-6919
Pojawia się w:
Opuscula Mathematica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Small-gain theorem for a class of abstract parabolic systems
Autorzy:
Grabowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/255288.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
control of infinite-dimensional systems semigroups
infinite-time LQ-control problem
Lur'e feedback systems
Opis:
We consider a class of abstract control system of parabolic type with observation which the state, input and output spaces are Hilbert spaces. The state space operator is assumed to generate a linear exponentially stable analytic semigroup. An observation and control action are allowed to be described by unbounded operators. It is assumed that the observation operator is admissible but the control operator may be not. Such a system is controlled in a feedback loop by a controller with static characteristic being a globally Lipschitz map from the space of outputs into the space of controls. Our main interest is to obtain a perturbation theorem of the small-gain-type which guarantees that null equilibrium of the closed-loop system will be globally asymptotically stable in Lyapunov's sense.
Źródło:
Opuscula Mathematica; 2018, 38, 5; 651-680
1232-9274
2300-6919
Pojawia się w:
Opuscula Mathematica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Discrete-time feedback stabilization
Autorzy:
Mitkowski, W.
Bauer, W.
Zagórowska, M.
Powiązania:
https://bibliotekanauki.pl/articles/229169.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
stabilization
feedback stabilization
finite dimensional stabilization
infinite dimensional systems
finite dimensional approximations
continuous-discrete system
Opis:
This paper presents an algorithm for designing dynamic compensator for infinitedimensional systems with bounded input and bounded output operators using finite dimensional approximation. The proposed method was then implemented in order to find the control function for thin rod heating process. The optimal sampling time was found depending on discrete output measurements.
Źródło:
Archives of Control Sciences; 2017, 27, 2; 309-322
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Approximate controllability of second order infinite dimensional systems
Autorzy:
Klamka, Jerzy
Khurshudyan, Asatur Zh.
Powiązania:
https://bibliotekanauki.pl/articles/1409079.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
infinite dimensional systems
approximate controllability
Green’s function approach
flexible Kirchhoff–Love plate
Opis:
In the paper approximate controllability of second order infinite dimensional system with damping is considered. Applying linear operators in Hilbert spaces general mathematical model of second order dynamical systems with damping is presented. Next, using functional analysis methods and concepts, specially spectral methods and theory of unbounded linear operators, necessary and sufficient conditions for approximate controllability are formulated and proved. General result may be used in approximate controllability verification of second order dynamical system using known conditions for approximate controllability of first order system. As illustrative example using Green function approach approximate controllability of distributed dynamical system is also discussed.
Źródło:
Archives of Control Sciences; 2021, 31, 1; 165-184
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Optimal multidrug treatment in the presence of drug resistance stemming from gene amplification
Autorzy:
Śmieja, J.
Świerniak, A.
Powiązania:
https://bibliotekanauki.pl/articles/332869.pdf
Data publikacji:
2002
Wydawca:
Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
Tematy:
nieskończenie wymiarowy system
optymalna kontrola
modelowanie biomedyczne
infinite dimensional systems
optimal control
biomedical modeling
Opis:
The paper is concerned with development of optimal treatment protocols that take into account both action of several drugs and the evolution of drug resistance. It is a result of analysis of evolution of drug resistance in cancer population but presented methodology can be applied in any case involving drug resistance stemming from gene amplification. First, a biological background is given. In subsequent sections of the paper, the developed technique is presented and some early analytical results, which form a basis for more precise modeling, are shown. Afterwards, the model description is transformed into a vector integro-differential equation, which makes it possible to define necessary conditions of optimal solution to the minimization problem arising from the search for the optimal treatment. Finally, some remarks on the model applicability are presented.
Źródło:
Journal of Medical Informatics & Technologies; 2002, 3; MI13-19
1642-6037
Pojawia się w:
Journal of Medical Informatics & Technologies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Well-posedness and stability analysis of hybrid feedback systems using Shkalikovs theory
Autorzy:
Grabowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/254925.pdf
Data publikacji:
2006
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
infinite-dimensional control systems
semigroups
spectral methods
Riesz bases
Opis:
The modern method of analysis of the distributed parameter systems relies on the transformation of the dynamical model to an abstract differential equation on an appropriately chosen Banach or, if possible, Hilbert space. A linear dynamical model in the form of a first order abstract differential equation is considered to be well-posed if its right-hand side generates a strongly continuous semigroup. Similarly, a dynamical model in the form of a second order abstract differential equation is well-posed if its right-hand side generates a strongly continuous cosine family of operators. Unfortunately, the presence of a feedback leads to serious complications or even excludes a direct verification of assumptions of the Hille-Phillips-Yosida and/or the Sova-Fattorini Theorems. The class of operators which are similar to a normal discrete operator on a Hilbert space describes a wide variety of linear operators. In the papers [12, 13] two groups of similarity criteria for a given hybrid closed-loop system operator are given. The criteria of the first group are based on some perturbation results, and of the second, on the application of Shkalikov's theory of the Sturm-Liouville eigenproblems with a spectral parameter in the boundary conditions. In the present paper we continue those investigations showing certain advanced applications of the Shkalikov's theory. The results are illustrated by feedback control systems examples governed by wave and beam equations with increasing degree of complexity of the boundary conditions.
Źródło:
Opuscula Mathematica; 2006, 26, 1; 45-97
1232-9274
2300-6919
Pojawia się w:
Opuscula Mathematica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exact Observability of Diagonal Systems With a One-Dimensional Output Operator
Autorzy:
Jacob, B.
Zwart, H.
Powiązania:
https://bibliotekanauki.pl/articles/908120.pdf
Data publikacji:
2001
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
obserwator
równanie Lyapunova
infinite-dimensional systems
unbounded observation operator
exact observability
Hautus test
Lyapunov equations
Opis:
In this paper equivalent conditions for exact observability of diagonal systems with a one-dimensional output operator are given. One of these equivalent conditions is the conjecture of Russell and Weiss (1994). The other conditions are given in terms of the eigenvalues and the Fourier coefficients of the system data.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2001, 11, 6; 1277-1283
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High-gain feedback and sliding modes in infinite dimensional systems
Autorzy:
Levaggi, L.
Powiązania:
https://bibliotekanauki.pl/articles/970418.pdf
Data publikacji:
2004
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
system nieskończenie wymiarowy
zaburzenia osobliwe
infinite dimensional systems
high-gain feedback
singular perturbations
sliding modes
Opis:
This paper focuses on the connection between sliding motions and low frequency modes of high-gain feedback systems in an infinite dimensional framework. We study a particular class of abstract control systems in a Hilbert space setting and analyse their high-gain behaviour through singular perturbations. We show that the "slow" motion derived from the reduced model approximates the evolution of the closed loop after a fast transient. Moreover we prove a relation between this slow component of the high-gain feedback system and sliding motions, in the spirit, of the analogous result in the finite dimensional setting by Young, Kokotovic and Utkin (Young et al., 1977).
Źródło:
Control and Cybernetics; 2004, 33, 1; 33-50
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Qualitative analysis of controlled drug resistance model - inverse Laplace and and semigroup approach
Autorzy:
Świerniak, A.
Polański, A.
Kimmel, M.
Bobrowski, A.
Śmieja, J.
Powiązania:
https://bibliotekanauki.pl/articles/205965.pdf
Data publikacji:
1999
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
modele biomedyczne
proces gałązkowy
stabilność
układy nieskończenie wymiarowe
biomedical models
branching processes
infinite dimensional systems
stability
Opis:
In this paper we study some properties of infinite models of the controlled evolution of drug resistance. We combine asymptotic techniques used in previous studies of similar models with methods of control theory and of semigroup theory. It enables us to find conditions for stability of the model both when the sensitive population is annihilated and when there exists a permanent influx from the sensivite compartment into drug resistant one. The conditions are expressed in terms of relationships between amplification and deamplification ratios as well as average life times of cells and intensity of anticancer drug action.
Źródło:
Control and Cybernetics; 1999, 28, 1; 61-73
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
On controllability of second order dynamical systems – a survey
Autorzy:
Klamka, J.
Wyrwał, J.
Zawiski, R.
Powiązania:
https://bibliotekanauki.pl/articles/202359.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
exact controllability
approximate controllability
second-order dynamical systems
infinite dimensional systems
semilinear systems
sterowalność
układ nieskończenie wymiarowy
system półliniowy
Opis:
The paper presents a survey of recent results in the area of controllability of second order dynamical systems. Controllability problem for finite and infinite dimensional, linear, semilinear, deterministic and stochastic dynamical systems (with delays and undelayed) is taken into consideration. Different types of controllability are discussed.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2017, 65, 3; 279-295
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 24

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