- Tytuł:
- Synthesis and antimicrobial activity of new adamantane derivatives I.
- Autorzy:
-
Orzeszko, Andrzej
Gralewska, Renata
Starościak, Bohdan
Kazimierczuk, Zygmunt - Powiązania:
- https://bibliotekanauki.pl/articles/1044397.pdf
- Data publikacji:
- 2000
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
imides
antimicrobial activity
adamantane derivatives - Opis:
- A series of fourteen derivatives of adamantane was synthesised. The new compound 4-(adamant-1-ylmethoxycarbonyl)phthalanhydride obtained from 1-adamantane- methanol and trimellitic anhydride chloride appeared very useful for preparation of a number of N-substituted phthalimides. Antimicrobial activity of the newly obtained derivatives such as, for example, 4-(adamant-1-ylmethoxycarbonyl)-N-(5-carboxypentamethylene)phthalimide or 4-(adamant-1-ylmethoxycarbonyl)-N-(L-alanyl)phthalimide was tested against Staphylococcus aureus, Bacillus sp., Micrococcus flavus and Enterococcus faecium. The minimal inhibitory concentration (MIC) for these compounds against S. aureus were 0.022 and 0.05 μg/ml, respectively.
- Źródło:
-
Acta Biochimica Polonica; 2000, 47, 1; 87-94
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł