Skocz do pozycji: 1.

Tytuł:

Leptin, gastrointestinal and stress hormones in response to exercise in fasted or fed subjects and before or after blood donation

Autorzy:

Sliwowski, Z.
Lorens, K.
Konturek, S.J.
Bielanski, W.
Zoladz, J.A.

Powiązania:

https://bibliotekanauki.pl/articles/70165.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

gut hormone
plasma level
leptin
pancreatic polypeptide
blood donation
insulin
catecholamine
growth hormone
exercise
stress
gastrin
hormone

Źródło:

Journal of Physiology and Pharmacology; 2001, 52, 1
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 2.

Tytuł:

Estrogenic properties of genistein acting on FSHR and LHR in rats with PCOS

Autorzy:

Zhang, T.
Chi, X.X.

Powiązania:

https://bibliotekanauki.pl/articles/2087577.pdf

Data publikacji:

2019

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

genistein
polycystic ovary syndrome
follicle-stimulating hormone receptor
luteinizing hormone receptor
female rat

Źródło:

Polish Journal of Veterinary Sciences; 2019, 1; 83-90
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 3.

Tytuł:

The use of fulvestrant in patients with advanced breast cancer

Autorzy:

Kufel-Grabowska, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1035843.pdf

Data publikacji:

2018

Wydawca:

Medical Education

Tematy:

breast cancer
fulvestrant
hormone therapy

Opis:

Breast cancer is the most common malignancy in women in Poland and the entire world, but thanks to early diagnostics and efficacious therapeutic methods, its prognosis is good. In some patients with advanced breast cancer, long-term survival is observed, which is why it is essential to select the most appropriate therapy, and to follow up on the course of disease and possible adverse events related to the treatment applied. The slow development of hormone-receptor-positive cancer, and a multitude of therapeutic options constitute a real challenge in palliative treatment. The use of fulvestrant resulted in a good response in both of the presented cases, and did not in any way comprise the daily lives of the patients over a long period of time.

Źródło:

OncoReview; 2018, 8, 1; 15-18
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 4.

Tytuł:

Hormonal changes in dairy cows during periparturient period
Zmiany hormonalne u krów mlecznych w okresie okołoporodowym

Autorzy:

Kurpińska, A.
Skrzypczak, W.

Powiązania:

https://bibliotekanauki.pl/articles/2615881.pdf

Data publikacji:

2019

Wydawca:

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie

Tematy:

dairy cow
hormonal change
periparturient period
prostaglandin F2 alpha
prolactin
human growth hormone
oxytocin
progesterone
estrogen
androgen
glycoprotein
gonadotrophin releasing hormone
luteinizing hormone
follicle stimulating hormone
thyroid hormone
cortisol
insulin

Źródło:

Acta Scientiarum Polonorum. Zootechnica; 2019, 18, 4; 13-21
1644-0714

Pojawia się w:

Acta Scientiarum Polonorum. Zootechnica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 5.

Tytuł:

Effects of corticotropin releasing hormone and corticotropin releasing hormone antagonist on biosynthesis of gonadotropin releasing hormone and gonadotropin releasing hormone receptor in the hypothalamic-pituitary unit of follicular-phase ewes and contribution of kisspeptin

Autorzy:

Ciechanowska, M.
Kowalczyk, M.
Lapot, M.
Malewski, T.
Antkowiak, B.
Brytan, M.
Winnicka, I.
Przekop, F.

Powiązania:

https://bibliotekanauki.pl/articles/70051.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

gonadotrophin releasing hormone
corticotrophin releasing hormone
luteinizing hormone
follicular phase
cerebral ventricle
kisspeptin
hypothalamus
cortisol secretion
adrenal steroid

Źródło:

Journal of Physiology and Pharmacology; 2018, 69, 3
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 6.

Tytuł:

Assessment of the influence of fluoride, modified transdermal replacement hormone therapy and supplement hormone therapy on unmanageable osteoporosis in postmenopausal women
Ocena wplywu fluoru, zmodyfikowanej przezskornej hormonoterapii zastepczej i doustnej hormonoterapii wspomaganej w leczeniu osteoporozy opornej u kobiet w okresie pomenopauzalnym

Autorzy:

Stanosz, M
Stanosz, S.
Puchalski, A.

Powiązania:

https://bibliotekanauki.pl/articles/15140.pdf

Data publikacji:

2009

Wydawca:

Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza

Tematy:

human disease
osteoporosis
woman
postmenopausal woman
fluoride
treatment
osteocalcin
hormone replacement therapy
hormone supplement therapy

Opis:

The study was conducted on 40 women in the early postmenopausal period, aged 52.3±3.1 years with primary osteoporosis unmanageable in treatment, divided into 2 groups based on a randomized list. Group I (n-20) was administered orally fluoride 0.25 mg kg-1 24 h-1 with modified transdermal hormone therapy/HRT, and group II (n-20) was administered orally fluoride and supplement hormonal therapy(HST) in 21 therapeutic cycle. The serum concentrations of osteocalcin (OC), procollagen(PICP), insulin-like growth factor I (IGF-1), prolactin basic (PRL) and prolactin after metoclopramide (PRL/ MCP) 4 times by using radioimmunoassy methods, before treatment and after 1, 3, 12 months of treatment. Bone mineral density (BMD) L2 – L4 was determined before treatment and at 12 month with a dualenergy x-ray absorptiometry scanner (Lunar DPX-1Q). In group I women receiving fluoride and transdermal HRT IGF-1 increased significantly while the concentrations of OC and PICP significantly decreased after 3 and 12 months of treatment but no statistically significant changes in the PRL concentration occurred. In group II women receiving orally fluoride and HST, a significant decrease in the concentration of IGF-1, OC after 3 and 12 months and a significant increase in the concentration of PRL and PRL/ MCP after 1, 3 and 12 months of treatment compared with the baseline values appeared. The concentration of type I procolagen (PICP) showed no statistically significant changes. Increase in bone mineral density was statistically significant L1, L2 (p < 0.05), L3, L4 (p < 0.01) compared with the baseline in the group receiving transdermal HRT. In women receiving fluoride and orally HST increase in the bone mineral density for L1 and L2 was non-insignificant, whereas for L3 and L4 it was significantly higher compared with the baseline (p < 0.05).
Badaniem objęto 40 kobiet we wczesnym okresie pomenopauzalnym, w wieku 52,3±3,1 lat, podzielonych wg listy randomizowanej na dwie grupy: grupę I. (n-20) otrzymującą doustnie fluor w dawce 0,25 mg kg-1 24 h-1 oraz zmodyfikowaną przezskórną hormonoterapię zastępczą (HTZ), grupę II (n-20) otrzymującą doustnie fluor w dawce 0,25 mg kg-1 24 h-1 i hormonoterapię wspomaganą (HTW) w postaci tabletek. Cykle terapeutyczne w obu grupach trwały 21 dni w miesiącu z następową przerwą 7 dni w celu wystąpienia krwawienia z odstawienia przez okres jednego roku. W surowicy oceniano stężenia osteokalcyny (OC), prokolagenu (PICP), insulinopodobnego czynnika wzrostu (IGF-1), podstawową prolaktynę (PRL) i po teście z metoklopramidem (PRL/MCP) radioimmunologicznie czterokrotnie: przed leczeniem oraz po 1. 3. i 12. miesiącu leczenia. Gęstość mineralną trzonów kręgów lędźwiowych L2 –L4 badano przed leczeniem i po 12 miesiącach leczenia densytometrem, firmy Luna (DPX-1Q), metodą DEXA. U kobiet z grupy I otrzymującej doustnie fluor i przezskórnie HTZ wystąpił znamienny wzrost stężenia IGF-1, znamienne obniżenie OC, PLCP po 3 i 12 miesiącach leczenia oraz brak statystycznych zmian w stężeniu prolaktyny. Natomiast u kobiet z grupy II otrzymującej w postaci tabletek doustnie fluor i hormonoterapię wspomaganą HTW wystąpiło znamienne obniżenie stężeń IGF-1, OC po 3 i 12 miesiącach leczenia oraz znamienny wzrost stężenia prolaktyny podstawowej i po teście z metoklopramidem po 1. 3. i 12. miesiącu leczenia w porównaniu z wartościami wstępnymi. Stężenia prokolagenu w czasie stosowania doustnie fluoru i HTW nie wykazywały znamiennych różnic. Gęstość mineralna L2-L4 wykazywała znamienne przyrosty u kobiet z grupy I. Natomiast u kobiet z grupy II gęstość mineralna L1, L2 nie wykazywała przyrostu znamiennego, a w kręgu L3, L4 występował znamienny przyrost w porównaniu z wartościami wyjściowymi (p < 0,01).

Źródło:

Journal of Elementology; 2009, 14, 3; 545-551
1644-2296

Pojawia się w:

Journal of Elementology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 7.

Tytuł:

The role of boron in animal health

Autorzy:

Kabu, M.
Uyarlar, C.
Zarczynska, K.
Milewska, W.
Sobiech, P.

Powiązania:

https://bibliotekanauki.pl/articles/961611.pdf

Data publikacji:

2015

Wydawca:

Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza

Tematy:

boron
enzyme
hormone
mineral
animal health

Opis:

Boron is a mineral used for various purposes in glass, ceramics, automotive and paint industries. Recently, boron has been confirmed to be an essential element for plants, animals and humans, although the knowledge of its biological effects is rather scanty. Boron is a dynamic trace element, and inorganic borates are transformed into boric acids and absorbed from mucosal surfaces, even when they are in low levels of physiological pH. It has been determined that boron affects many enzymes, bone development, mineralization, Ca, P, Mg and energy metabolism. Boron mineral compounds can be effective in optimizing the performance of an organism, treatment of bone structure disorders, reduction of cholesterol and triglyceride levels. Beside the effects it produces specifically on fat and lipid metabolisms, boron can influence the activity of vitamin D and affect some disorders connected with its deficiency. Although several studies on effects of boron on some mechanisms have been conducted over the last ten years, the available information remains insufficient.

Źródło:

Journal of Elementology; 2015, 20, 2
1644-2296

Pojawia się w:

Journal of Elementology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 8.

Tytuł:

Prostate cancer in an elderly patient with a history of comorbidities

Autorzy:

Stryczyńska-Mirocha, Adriana
Mirocha, Martyna

Powiązania:

https://bibliotekanauki.pl/articles/22676694.pdf

Data publikacji:

2023-03-31

Wydawca:

Medical Education

Tematy:

prostate cancer
hormone therapy
nmCRPC
apalutamide

Opis:

Prostate cancer is the most common cancer in men in Poland. The choice of treatment method depends on many factors, including the stage of the disease, the patient's age, life expectancy, the presence of comorbidities and the general condition of the patient. Hormone therapy is one of the basic methods of prostate cancer treatment, both in adjuvant and palliative treatment. Castration-resistant prostate cancer is an incurable disease. However, the introduction of new hormonal drugs to therapy significantly extended the survival time of patients with relatively low harmfulness of therapy.

Źródło:

OncoReview; 2023, 13, 1; 3-5
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 9.

Tytuł:

Effects of polybrominated diphenyl ethers on thyroid hormone, neurodevelopment and fertility in rodents and humans

Autorzy:

Czerska, Marta
Zieliński, Marek
Kamińska, Joanna
Ligocka, Danuta

Powiązania:

https://bibliotekanauki.pl/articles/2179114.pdf

Data publikacji:

2013-08-01

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

PBDEs
thyroid hormone
neurodevelopment
fertility
rodents
humans

Opis:

Polybrominated diphenyl ethers (PBDEs) are used as flame retardants. Due to their widespread use in many consumer products, PBDEs can be found in food as well as in the environment. Their presence has also been found in the human serum, human adipose tissue and human breast milk. Results of experimental studies suggest that the presence of PBDE in the environment is not neutral to our health. In rats and mice exposed to PBDE disturbances in thyroid hormone homeostasis and reproductive system such as changes in reproductive organs weight and disorders in sperm motility and motion were found. In rodents, pre- and postnatal exposure to PBDE can cause neurobehavioral effects. Also in humans disturbances in thyroid hormone system, weight of reproductive organs and concentrations of sex hormones associated with PBDEs serum concentrations were found. Exposure to PBDEs during pregnancy may lead to slower mental and psychomotor development in infants. In this paper the results of previous animal a nd human studies are reviewed.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2013, 26, 4; 498-510
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 10.

Tytuł:

Could fructan sources in strawberry matrix be more effective as a tool for improvement of bone structure than these compounds added to diet alone? - Study on osteopenic rat model

Autorzy:

Topolska, K.
Radzki, R.P.
Filipiak-Florkiewicz, A.
Bieńko, M.
Florkiewicz, A.
Cieślik, E.

Powiązania:

https://bibliotekanauki.pl/articles/2085394.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

ovarian hormone deficiency
calcium intake
fructans
bone

Opis:

Introduction. Osteoporosis, a disease associated with ovarian hormone deficiency following menopause, is the most common cause of age-related bone loss. Although an optimal intake of Ca is vital – both bone accretion during growth and maintenance in adult life – a great percentage of the population consumes far below the recommended amounts of this mineral. On the other hand, there are evidences that fructans enhance not only Ca absorption, but bone calcium as well. Objective. In the knowledge that estrogen deficiency and insufficient Ca in the diet during postmenopause cause serious problems with resultant osteoporosis, the aim of this study is to assess the effects of a diet enriched in fructan-containing sources alone, or in the “strawberry matrix”, on the structure of bone in OVX rats under calcium hypoalimentation. Materials and method. Experimental animals were female Wistar rats, sham-operated or ovariectomized. The treatment with Ca-restricted diets also contained one of the sources of fructan (Jerusalem artichoke, yacon, Beneo Orafti Synergy1), in the amount providing 8% of fructans. Femur architecture of rats was assessed by tomography and Ca content by the AAS method. Results. Ovariectomy led to a significant decrease in femoral Ca content, total mineral content and bone density of rats. This study shows that a diet containing inulin-type fructan (especially as a component of strawberry product) improved bone quality (i.e. increase in Ca content in femur, total density in middle part of bone, as well as decrease of endosteal circumference) in OVX rats under calcium hypoalimentation. Conclusions. These findings suggest that a fructan-enriched diet could be potentially useful for postmenopausal osteoporosis. It is important to determine an optimal dietary level of fructan with the long-term goal of developing a dietary strategy in osteoporosis prevention.

Źródło:

Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 19-28
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 11.

Tytuł:

A brief overview of the process of the elucidation of GnRH structure (1971)

Autorzy:

Kochman, K.

Powiązania:

https://bibliotekanauki.pl/articles/80024.pdf

Data publikacji:

2012

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

luteinizing hormone
follicle stimulating hormone
receptor protein
protein G
cell membrane
hypothalamic peptide
adrenocorticotrophin
radioimmunoassay
central nervous system
gonadotrophin releasing hormone
receptor
neuroendocrinology

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2012, 93, 4
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 12.

Tytuł:

LH-hCG receptors in the porcine uterus - a new evidence of their presence in the cervix

Autorzy:

Stepien, A.
Derecka, K.
Gawronska, B.
Bodek, G.
Zwierzchowski, L.
Shemesh, M.
Ziecik, A.J.

Powiązania:

https://bibliotekanauki.pl/articles/69020.pdf

Data publikacji:

2000

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

uterus
pig
human chorionic gonadotrophin
endometrium
thyrotrophic hormone
receptor
bovine serum albumin
myometrium
luteinizing hormone
corpus luteum
cervix

Źródło:

Journal of Physiology and Pharmacology; 2000, 51, 4,2
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 13.

Tytuł:

Free intracellular calcium [(CA2plus)i] in opioid sensitive cells of the porcine anterior pituitary

Autorzy:

Szafranska, B.
Tilton, J.E.

Powiązania:

https://bibliotekanauki.pl/articles/69614.pdf

Data publikacji:

2000

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

naloxone
pig
anterior pituitary
intracellular calcium
calcium
opioid
hypothalamic hormone
gonadotrophin releasing hormone
in vitro

Źródło:

Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 14.

Tytuł:

Research on the effect of an androgenic hormone product on the functional status of common sebaceous glands in dogs

Autorzy:

Gâjâilă, G.
Ghiță, M.
Zagrai, G.
Cotor, D.C.
Ionescu, A.M.
Zagrai (Măierean), A.M.
Damian, A.
Cotor, G.

Powiązania:

https://bibliotekanauki.pl/articles/16539314.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czasopisma i Monografie PAN

Tematy:

sebaceous glands
sebum
pH
androgenic hormone

Opis:

Nowadays, a high incidence of cutaneous tumors is observed in domestic carnivorous in pet clinic, the sebaceous glands being the starting point for the development of these tumors. The hormonal imbalances are considered to be the most common etiology for these tumors, so the current research is based on the effects of an androgenic like hormonal drug on the functionality of the sebaceous glands in dogs. For this purpose, 32 dogs were distributed in 4 groups: control group 1 (8 dogs - females), control group 2 (8 dogs - males), experimental group 1 (8 dogs - females) and experimental group 2 (8 dogs - males). The investigation targeted the pH of skin and the rate of sebum’s secretion. The animals from the experimental groups were treated with Anabolin forte for 2 days at a dose of 1 mg/kg body weight/day, intramuscular. The obtained results revealed that administration of Anabolin forte in males induced a significantly distinct intensification (with 10.66%) of sebum’s secretion and a significant decrease of pH of the skin (with 17.1%) compared to the animals from the control group. The administration of Anabolin forte in females induced a significantly distinct intensification (with 17.47%) of sebum’s secretion and a significant decrease of the pH of the skin (with 14.32%) compared to the animals from the control group.

Źródło:

Polish Journal of Veterinary Sciences; 2022, 25, 3; 397-402
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 15.

Tytuł:

Moje samopoczucie – polska adaptacja kwestionariusza Menopause Symptom List Janette M. Perz
Polish adaptation of the menopause symptom list ny Janette M. Perz

Autorzy:

Bielawska-Batorowicz, Eleonora

Powiązania:

https://bibliotekanauki.pl/articles/2139124.pdf

Data publikacji:

2004

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

menopause
menopausal symptoms
hormone replacement therapy

Opis:

Menopause Symptom List was developed in Australia as a tool to depict severity and intensity of symptoms related to menopause. Three scales of the questionnaire – psychological, vasomotor and somatic symptoms – were extracted by factor analysis. The paper gives account of the Polish version of the questionnaire (Moje samopoczucie), its validity and reliability. Factor analysis has confirmed the original 3 factors structure of the questionnaire. Realiability coefficients (test-retest, Cronbach’s and Spearmann-Brown’s coefficient) were sufficiently high. Validity was estimated by comparing the results of the questionnaire and a physician’s evaluation of intensity and severity of menopausal symptoms. Most subjects with high questionnaire scores were also given high scores on medical record. Results of women with different menopausal status were significantly different. The scores changed significantly in women treated with hormone replacement therapy. All these results indicate that Polish version of Menopause Symptom List is a valid tool to be used in studies on menopausal transition.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2004, 08; 45-54
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 16.

Tytuł:

Three interesting cases of syndrome of inappropriate antidiuretic hormone secretion

Autorzy:

Dyczko, M.
Sawa, M.
Grzywa-Celinska, A.
Szmygin-Milanowska, K.
Kuczynska, M.
Mosiewicz, J.

Powiązania:

https://bibliotekanauki.pl/articles/3079.pdf

Data publikacji:

2015

Wydawca:

Instytut Medycyny Wsi

Tematy:

disease syndrome
inappropriate antidiuretic hormone secretion
hyponatremia
diagnostics

Opis:

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is an etiologically-diverse pathological condition resulting from the elevation in both ectopic and autonomic secretion of the antidiuretic hormone (ADH) by neoplastic tissue; excessive stimulation of the hypothalamic-pituitary axis, e.g. in pulmonary diseases, central nervous system (CNS) abnormalities, endocrine glands dysfunction or due to the use of some medications; intensification of renal ADH action by certain medications and action of substances chemically-related to vasopressin. The clinical characteristics of the syndrome are comprised of the presence of inadequately concentrated urine, hyponatremia, and hypo-osmolal blood serum, as well as weight gain. To show the variety of its causes and courses the article presents three cases of patients diagnosed with SIADH in the Department of Internal Medicine. In each of them the syndrome of inappropriate antidiuretic hormone secretion manifested in clinical laboratory tests in the form of hyponatremia.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 17.

Tytuł:

Investigation of diagnostic use of serum anti-Müllerian hormone concentration in dioestrus and anoestrus bitches before and after ovariohysterectomy and therelationship with ovarian follicle numbers

Autorzy:

Anadol, E.
Gultiken, N.
Yarim, G.F.
Karaca, E.
Kanca, H.
Yarim, M.

Powiązania:

https://bibliotekanauki.pl/articles/2087297.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

anti-Müllerian hormone
aneostrus
bitch
dieostrus
ovarian follicles

Źródło:

Polish Journal of Veterinary Sciences; 2020, 23, 3; 391-397
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 18.

Tytuł:

The associations between the growth hormone/insulin-like growth factor-1 axis, adiponectin, resistin and metabolic profile in children with growth hormone deficiency before and during growth hormone treatment

Autorzy:

Witkowska-Sędek, Ewelina
Rumińska, Małgorzata
Stelmaszczyk-Emmel, Anna
Majcher, Anna
Pyrżak, Beata

Powiązania:

https://bibliotekanauki.pl/articles/1038412.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

adiponectin
resistin
metabolic profile
growth hormone/insulin-like growth factor-1 axis
growth hormone deficiency
children

Opis:

This study investigated associations between the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, adiponectin, resistin and metabolic profile in 47 GH-deficient children before and during 12 months of GH treatment. 23 short age-matched children without growth hormone deficiency (GHD) or any genetic or chronic disorders were recruited as controls at baseline. Metabolic evaluation included measurements of adiponectin, resistin, IGF-1, total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), glucose, insulin, glycated haemoglobin (HbA1c), thyroid stimulating hormone (TSH) and free thyroxine (free T4) concentrations. The GH-deficient children had significantly higher adiponectin (p<0.05) and total cholesterol (p<0.05) levels, and a significantly lower level of resistin (p<0.05) than the controls. Resistin at 6 months of GH treatment significantly correlated with changes in height SDS in that period (r=0.35) and with the level of fasting insulin (r=0.50), the HOMA-IR (r=0.56) and the QUICKI (r=-0.53) at 12 months of therapy. Adiponectin level at 12 months of GH treatment was significantly associated with changes in HDL-C within the first 6 (r=0.73) and within 12 (r=0.56) months of therapy, while resistin significantly correlated with an increment in IGF-1 within 12 months of treatment (r=0.49) and with total-C at 12 months (r=0.56). Untreated GH-deficient children had higher adiponectin and lower resistin levels than healthy short children without GHD. Adiponectin and resistin levels did not change significantly during the first 12 months of GH therapy. Good responders to GH treatment had a tendency for higher resistin level during GH therapy, which positively correlates with the insulin resistance parameters.

Źródło:

Acta Biochimica Polonica; 2018, 65, 2; 333-340
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 19.

Tytuł:

Leczenie przerzutowego, hormonozależnego, HER-2 ujemnego raka piersi – czy jest miejsce dla ewerolimusu? Opis przypadku
Treatment of metastatic, hormone receptor-positive HER2-negative breast cancer – is everolimus still an option? A case report

Autorzy:

Grela-Wojewoda, Aleksandra
Pacholczak-Madej, Renata

Powiązania:

https://bibliotekanauki.pl/articles/1580661.pdf

Data publikacji:

2021

Wydawca:

Krakowska Akademia im. Andrzeja Frycza Modrzewskiego

Tematy:

rak piersi
hormonooporność
hormonoterapia
terapia ukierunkowana molekularnie
breast cancer
hormone resistance
hormone therapy
molecularly targeted therapy

Opis:

Rak piersi jest najczęściej występującym na świecie nowotworem złośliwym u kobiet. Obecnie standardem postępowania w leczeniu rozsianego, hormonozależnego, HER-2 ujemnego raka piersi, bez cech kryzy trzewnej jest terapia hormonalna z inhibitorami kinaz cyklinozależnych (CD4/6). Ewerolimus, pochodna rapamycyny, nie jest obecnie rutynowo stosowany w praktyce klinicznej, jednak wykazano jego skuteczność w skojarzeniu z hormonoterapią. W artykule zaprezentowano przypadek pacjentki z nawrotowym, hormonoopornym rakiem piersi, u której zastosowano ewerolimus z eksemestanem w ramach terapii niestandardowej po dwóch liniach paliatywnej hormonoterapii (inhibitor aromatazy i fulwestrant) i chemioterapii FAC (fluorouracyl, adriamycyna, cyklofosfamid). Zastosowane leczenie zapewniło 24-miesięczny czas wolny od nawrotu choroby. Miejsce ewerolimusu w leczeniu zaawansowanego raka piersi w obecnej erze leczenia cyklibami (inhibitory cyklin CD4/6) jest poddawane ocenie w toczących się badaniach klinicznych.
Among females, breast cancer is across the world the most common malignancy. Currently, the standard in the treatment of metastatic, hormone receptor-positive HER2-negative breast cancer without visceral crisis, is hormonal therapy with cyclin-dependent kinase 4 and 6 (CDK 4/6) inhibitors. Everolimus, a rapamycin derivative, is not routinely used in clinical practice but together with hormonal therapy it has been found to be an effective treatment option. We present a patient with recurrent, hormone-resistant breast cancer who was treated with everolimus with exemestane in beyond-standard therapy after two lines of palliative hormonal therapy (aromatase inhibitor and fulvestrant) and chemotherapy FAC (fluorouracil, adriamycin, cyclophosphamide). This treatment provided 24-months of progression-free survival. The place of everolimus in the treatment of advanced breast cancer in the era of CDK 4/6 inhibitors is being investigated in clinical trials.

Źródło:

Państwo i Społeczeństwo; 2021, 1; 153-162
1643-8299
2451-0858

Pojawia się w:

Państwo i Społeczeństwo

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 20.

Tytuł:

Oxidative stress and antioxidants markers in individuals with thyroid hormones dysfunction

Autorzy:

Omon, Emmanuel Akokhamen
Ajay, Olawale David

Powiązania:

https://bibliotekanauki.pl/articles/29520465.pdf

Data publikacji:

2023-12-31

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

antioxidants
dysfunction
malondialdehyde
oxidative stress
thyroid hormone

Opis:

Introduction and aim. Thyroid hormone abnormalities have been associated with oxidative changes in human beings. The aim of the study was to evaluate the oxidative stress marker and antioxidants status in individuals with thyroid hormone dysfunction in Ekiti State. Material and methods. A total of eighty samples were recruited in this study comprising forty subjects with thyroid hormones dysfunction and forty apparently healthy controls. Malondialdehyde (MDA), reduced glutathione (GSH) and catalase were determined spectrophotometerically. Results. MDA was non-significantly higher (p>0.05) in subjects (4.33±0.84 nmol/mL) compared with control (4.12±0.63 nmol/mL), catalase was non-significantly higher (p>0.05) in subjects (199.36±20.21 µm/mL) compared with control (181.55±16.61 µm/mL), while GSH was significantly lower (p<0.05) in subjects (79.31±10.12 µmol/mL) compared with control (127.21±7.29 µmol/mL). Conclusion. It can be concluded that the increase in the reactive oxygen species accompanied with impairment of the antioxidant system occurs in patients with thyroid hormone dysfunction. Hypothyroidism and hyperthyroidism induces disequilibrium of the oxidative/anti-oxidative balance that can lead to subsequent development of inflammation and associated diseases.

Źródło:

European Journal of Clinical and Experimental Medicine; 2023, 4; 768-775
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 21.

Tytuł:

Genetic diversity in populations of Slovak Spotted cattle based on single nucleotide polymorphisms analyses

Autorzy:

Moravčíková, Nina
Trakovická, Anna
Navrátilová, Alica

Powiązania:

https://bibliotekanauki.pl/articles/1039494.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

cattle
growth hormone
leptin
leptin receptor
polymorphism

Opis:

The aim of this study was to identify SNPs in leptin (LEP), leptin receptor (LEPR) and growth hormone (GH) genes in order to analyze genetic diversity of Slovak Spotted cattle. The total numbers of blood samples were taken from 353 Slovak Spotted cows originating from four farms. Genomic DNA was isolated by phenol-chloroform extraction method and analyzed by PCR-RFLP method. After digestion with restriction, enzymes were detected in whole population of cow's alleles with frequency: LEP/Sau3AI A 0.84 and B 0.16 (±0.0152); LEPR/BseGI C 0.95 and T 0.05 (±0.0089) and GH/AluI L 0.70 and V 0.30 (±0.0188). Based on the observed vs. expected genotypes frequencies populations across loci were in Hardy-Weinberg equilibrium (P\>0.05). Predominant for SNP LEP/Sau3AI was AA genotype (0.70), for SNP LEPR/T945M CC genotype (0.91), and LL genotype (0.48) was most frequent for SNP GH/AluI. The observed heterozygosity of SNPs across populations was also transferred to the low or median polymorphic information content 0.24 (He 0.28), 0.08 (He 0.09) and 0.33 (He 0.47) for LEP, LEPR and GH genes, respectively. Within genetic variability estimating negative values of fixation indexes FIS (-0.09-0.05) and FIT (-0.07-0.03) indicating heterozygote excess were observed. The value of FST indexes (0.018-0.023) shows very low levels of genetic differentiation in allele frequencies of loci among evaluated subpopulations. The low values of genetic distances (0.0018-0.0159) indicated high genetic relatedness among animals in subpopulations caused probably by common ancestry used in breeding program at farms.

Źródło:

Acta Biochimica Polonica; 2013, 60, 4; 807-810
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 22.

Tytuł:

Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones

Autorzy:

Kunc, Michał
Gabrych, Anna
Witkowski, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/1038795.pdf

Data publikacji:

2016

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

microbiome
lipopolysaccharide
estrogens
thyroid hormones
growth hormone

Opis:

Commensal bacteria and their genes associated with host are known as microbiome. In recent years, microbial influence on host endocrine system has been under detailed investigation. The role of microbiome in the pathogenesis of insulin resistance and obesity, the function of hypothalamic-pituitary-adrenal axis and secretion of hormones regulating appetite is well described in world literature. In this article we discuss poorly reviewed issues: the microbiome role in modulation of non-peptide (sex and thyroid) and peptide (growth hormone and parathyroid hormone) functions. Understanding complex bidirectional relations between host endocrine system and bacteria is of fundamental importance to understanding microbial impact on host reproduction, risk of endocrine-related cancers, pathogenesis of non-thyroidal illness syndrome, growth failure in children and hormonal changes during chronic kidney disease. This article also highlights effects of dietary compounds on microbiome composition and bacterial enzymes activity, and thus host hormonal status.

Źródło:

Acta Biochimica Polonica; 2016, 63, 2; 189-201
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 23.

Tytuł:

Osocze vs surowica – czy rodzaj materiału biologicznego ma wpływ na wyniki oznaczeń parathormonu?
Plasma vs serum – does the type of biological material affects the results of parathyroid hormone determinations?

Autorzy:

Beda-Maluga, Karolina
Paczuszka, Paulina
Pisarek, Hanna
Świętosławski, Jacek
Winczyk, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/1035389.pdf

Data publikacji:

2019

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

surowica
osocze
parathormon
serum
plasma
parathyroid hormone

Opis:

Introduction: The recommended biological material for the parathyroid hormone (PTH) assay is venous blood plasma. According to diagnostic kit manufacturers, the PTH concentration can also be determined in blood serum. The aim of the study was to determine whether differences exist between PTH measured in serum and in plasma. Material and methods: The study was conducted on venous blood samples (plasma and serum) obtained from 92 patients at the Clinic of Endocrinology, University Hospital WAM – CSW. The PTH concentration was measured with an Immulite 1000 analyzer (Siemens), and iPTH kit. Results: The PTH values in plasma and serum were the same only in 3 cases. In 46 samples (50%), a higher hormone level was observed in the plasma, and in 43 cases (47%), a higher concentration was obtained in serum. The absolute differences between the PTH values in the tested biological materials ranged from 0 to 38 pg/mL, and increased together with the hormone concentration. The relative differences (percentage ratio of absolute differences to plasma PTH concentration) ranged from 0 to 34.3%. However, neither the absolute nor the relative differences were statistically significant (p > 0.05). The classification of PTH concentrations according to the reference values for each biological material (i.e. normal, reduced or elevated) was found to be concordant in 83 tested samples (90%). Conclusion: The identified PTH concentrations in the plasma and serum were not identical but comparable and in most cases the differences did not affect the clinical interpretation of the results.
WSTĘP: Materiałem biologicznym zalecanym do oznaczania parathormonu (parathyroid hormone – PTH) jest osocze krwi żylnej pobranej na wersenian sodowo-potasowy, jednak według producentów zestawów diagnostycznych do pomiaru PTH można stosować zarówno osocze, jak i surowicę krwi. Celem pracy było zbadanie, czy wartości PTH oznaczane w surowicy i w osoczu krwi żylnej są porównywalne. MATERIAŁ I METODY: W badaniu wykorzystano próbki krwi żylnej (osocze i surowica) uzyskane od 92 pacjentów Poradni Endokrynologicznej Uniwersyteckiego Szpitala Klinicznego im. Wojskowej Akademii Medycznej – Centralnego Szpitala Weteranów (USK im. WAM – CSW) w Łodzi. Oznaczenia hormonu wykonano na analizatorze Immulite 1000 (Siemens) zestawem iPTH. WYNIKI: Wartości PTH oznaczone w osoczu i w surowicy były jednakowe tylko w 3 przypadkach. W 46 próbkach (50%) wyższe wartości hormonu odnotowano w osoczu, a w 43 przypadkach (47%) w surowicy. Różnice bezwzględne między wartościami PTH w badanych materiałach wahały się od 0 do 38 pg/mL i zwiększały się wraz ze wzrostem stężenia hormonu. Różnice względne (procentowy stosunek różnic bezwzględnych do stężenia PTH w osoczu) wynosiły od 0 do 34,3%. Jednak zarówno różnice bezwzględne, jak i względne nie były znamienne statystycznie (p > 0,05). Po klasyfikacji stężeń – na prawidłowe, obniżone lub podwyższone – na podstawie wartości referencyjnych PTH dla danego materiału biologicznego uzyskano zgodność wyników w 83 badanych próbkach (90%). WNIOSKI: Stężenia PTH oznaczane w osoczu i w surowicy nie są identyczne, ale porównywalne, a różnice w większości przypadków nie wpływają na interpretację kliniczną wyników.

Źródło:

Annales Academiae Medicae Silesiensis; 2019, 73; 25-30
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 24.

Tytuł:

Interaction between meristem tissue layers controls phyllotaxis

Autorzy:

Kierzkowski, D.
Smith, R.
Lenhard, M.
Kuhlemeier, C.

Powiązania:

https://bibliotekanauki.pl/articles/80571.pdf

Data publikacji:

2013

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

conference
phyllotaxis
plant hormone
auxin
Arabidopsis
meristem
tissue layer

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 25.

Tytuł:

Partial deglycosylation of α subunit modifies sturgeon gonadotropin function.

Autorzy:

Zenkeviès, Henriks
Vose, Vija
Vosekalne, Ilze
Bcena, Ausma

Powiązania:

https://bibliotekanauki.pl/articles/1044331.pdf

Data publikacji:

2000

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

α subunit
CD spectrum
sturgeon GTH
gonadotropic hormone
deglycosylation

Opis:

Chemical deglycosylation (dg) of sturgeon Acipenser gueldenstaedti Br. (αGTH) resulted in the loss of 83% of its initial carbohydrate content. It altered also recombinant dgαGTH + βGTH dimer molecule, reducing its immunoreactivity by 30%, and fully blocking the hormonal function. CD spectroscopy showed that deglycosylation led to changes in the secondary structure of dgαGTH and in the α-β recombinant. The sugar moiety of sturgeon αGTH is suggested to play an important role in maintaining the biological function of the hormone dimer molecule.

Źródło:

Acta Biochimica Polonica; 2000, 47, 3; 815-819
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 26.

Tytuł:

Polymorphism of the porcine growth hormone gene and its linkage to microsatellites S0083 and S0090

Autorzy:

Korwin-Kossakowska, A
Pierzchala, M.
Kuryl, J.
Zwierzchowski, L.
Cymerowska-Prokopczyk, I.
Siadkowska, E.

Powiązania:

https://bibliotekanauki.pl/articles/2043894.pdf

Data publikacji:

1999

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

pig
gene
polymorphism
microsatellite
Sus scrofa
linkage
growth hormone

Źródło:

Journal of Applied Genetics; 1999, 40, 2; 85-91
1234-1983

Pojawia się w:

Journal of Applied Genetics

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 27.

Tytuł:

Plasma thyroid hormones and corticosterone levels in blood of chicken embryos and post hatch chickens exposed during incubation to 1800 MHz electromagnetic field

Autorzy:

Pawlak, Krzysztof
Sechman, Andrzej
Nieckarz, Zenon

Powiązania:

https://bibliotekanauki.pl/articles/2178802.pdf

Data publikacji:

2014-01-01

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

electromagnetic fields
mobile phone
thyroid hormone
corticosterone
chicken embryo

Opis:

Introduction: This study attempted to determine the effect of a 1800 MHz electromagnetic field (EMF) (only carrier frequency) on thyroxine (T₄), triiodothyronine (T₃) and corticosterone (CORT) concentrations in the blood plasma of chick embryos, and to investigate the effect of electromagnetic field (EMF) exposure during embryogenesis on the level of these hormones in birds that are ready for slaughter. Material and Methods: Throughout the incubation period, embryos from the experimental group were exposed to a 1800 MHz EMF with power density of 0.1 W/m², 10 times during 24 h for 4 min. Blood samples were collected to determine T₄, T₃ and CORT concentrations on the 12th (E12) and 18th (E18) day of incubation, from newly hatched chicks (D1) and from birds ready for slaughter (D42). Results: The experiment showed that T₄ and T₃ concentrations decreased markedly and CORT levels increased in the embryos and in the newly hatched chicks exposed to EMF during embryogenesis. However, no changes were found in the level of the analyzed hormones in the birds ready for slaughter. Differences in T₄ and T₃ plasma concentrations between the EMF-exposed group and the embryos incubated without additional EMF were the highest in the newly hatched chicks, which may be indicative of the cumulative effect of electromagnetic field on the hypothalamo-pituitary-thyroid axis (HPT). Discussion: The obtained results suggest that additional 1800 MHz radio frequency electromagnetic field inhibits function of HPT axis, however, it stimulates hypothalamo- pituitary-adrenal axis by inducing adrenal steroidogenic cells to synthesize corticosterone. Further investigations are needed to elucidate the mechanisms by which radio EMFs affect HPT and HPA axis function in the chicken embryos.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2014, 27, 1; 114-122
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 28.

Tytuł:

Gonadotropin-releasing hormone and kisspeptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland

Autorzy:

Zielinska-Gorska, M.
Gorski, K.
Biernacka, K.
Sawosz, E.
Kaminski, T.
Gajewska, A.

Powiązania:

https://bibliotekanauki.pl/articles/69453.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

gonadotrophin releasing hormone
neuronal network
mRNA expression
kisspeptin-10
nuclear receptor
anterior pituitary gland
ovariectomy
luteinizing hormone
rat

Źródło:

Journal of Physiology and Pharmacology; 2018, 69, 3
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 29.

Tytuł:

Association of the DdeI growth hormone gene polymorphism with some performance traits in Polish Large White and Czech Large White x Polish Large White pigs

Autorzy:

Putnova, L
Krenkova, L.
Vrtkova, I.
Dvorak, J.
Pietruszka, A.
Czarnecki, R.

Powiązania:

https://bibliotekanauki.pl/articles/2041758.pdf

Data publikacji:

2001

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

pig
carcass trait
polymorphism
gene
GH gene
Czech Large White pig
DdeI growth hormone
growth hormone
growth trait
Polish Large White breed

Źródło:

Journal of Applied Genetics; 2001, 42, 3; 317-324
1234-1983

Pojawia się w:

Journal of Applied Genetics

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 30.

Tytuł:

Exogenous steroid hormones stimulate full development of autonomous endosperm in Arabidopsis thaliana

Autorzy:

Rojek, J.
Pawelko, L.
Kapusta, M.
Naczk, A.
Bohdanowicz, J.

Powiązania:

https://bibliotekanauki.pl/articles/59176.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Botaniczne

Tematy:

steroid hormone
endosperm
Arabidopsis thaliana
apomixis
DNA methylation

Opis:

Most flowering plants, including important crops, require double fertilization to form an embryo and endosperm, which nourishes it. Independence from fertilization is a feature of apomictic plants that produce seeds, from which the plants that are clones of the mother plant arise. The phenomenon of apomixis occurs in some sexual plants under specific circumstances. Since the launch of a fertilization-independent mechanism is considered a useful tool for plant breeding, there have been efforts to artificially induce apomixis. We have been able to produce fertilization-independent endosperm in vitro in Arabidopsis over the last few years. This paper demonstrates the methods of improving the quality of the endosperm obtained using plant and mammalian steroid hormones. Additionally, it shows the study on the autonomous endosperm (AE) formation mechanism in vitro. This paper examines the effect of exogenous steroid hormones on unfertilized egg and central cell divisions in culture of unpollinated pistils of Arabidopsis Col-0 wild-type andfie-1 mutant. All media with hormones used (estrone, androsterone, progesterone, and epibrassinolide) stimulated central cell divisions and fertilization-independent endosperm development. The stages of AE development followed the pattern of Arabidopsis thaliana wild type after fertilization. Subsequent stages of AE were observed from 2-nuclear up to cellular with the most advanced occurring on medium with 24-epibrassinolide and progesterone. The significant influence of mammalian sex hormones on speed of AE development and differentiation was noticed. Using restriction analysis, the changes in methylation of FIE gene was established under in vitro condition. The authors of this paper showed that Arabidopsis thaliana has a high potency to fertilization-independent development.

Źródło:

Acta Societatis Botanicorum Poloniae; 2015, 84, 2
0001-6977
2083-9480

Pojawia się w:

Acta Societatis Botanicorum Poloniae

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 31.

Tytuł:

Abiraterone acetate - 10 clinically relevant facts

Autorzy:

Żołnierek, Jakub

Powiązania:

https://bibliotekanauki.pl/articles/2047213.pdf

Data publikacji:

2021-09-30

Wydawca:

Medical Education

Tematy:

prostate cancer
systemic therapy
hormone therapy
abiraterone acetate

Opis:

Prostate cancer is one of the most frequently diagnosed cancers in men. Number of newly diagnosed cases is increasing due to several factors and the most important ones seem to be: population ageing and more sensitive diagnostic procedures. Secondary – the higher efficacy of treatment with its influence on improving patients’ overall survival and the specific mechanism of action of drugs used in systemic therapy lead to growing population of men suffering from prostate cancer in general and, specifically – patients with castration resistance. It is hormone therapy to play the key role in systemic treatment of prostate cancer with increasing significance of novel drugs focused on inhibition of molecular signal transduction mediated by androgen receptor. Abiraterone acetate is the representative of this therapeutic class. The paper describes the most clinically relevant data regarding the drug.

Źródło:

OncoReview; 2021, 11, 3; 80-84
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 32.

Tytuł:

Rys historyczny leczenia raka piersi
Historic perspective of breast cancer treatment

Autorzy:

Pietrzyńska, Tatiana
Podwińska, Ewa
Olejek, Anita
Turek, Sebastian
Mazur, Jakub

Powiązania:

https://bibliotekanauki.pl/articles/908438.pdf

Data publikacji:

2007

Wydawca:

Medical Communications

Tematy:

breast cancer
chemotherapy
history
hormone therapy
radiotherapy
surgical techniques
treatment

Opis:

The authors took interest in historical aspects of treatment of breast cancer over past centuries. The first mentions of breast tumours or lumps appeared in Egyptian writings 3 thousand years ago. Etymology of the word “cancer” was explained by Paul of Egina by the resemblance of blood-engorged veins adjacent to breast tumour to crab legs. Ancient doctors not only diagnosed this disease, but also made attempts at treating it. Roman doctors considered breast cancer as a local disease and treated it by radical excision, including pectoral muscle. Greek doctor, Galen, was the first to consider breast cancer as a systemic disease and tried to treat it conservatively using herbal extracts of mandrake and cabbage. Cessation of progress of medicine characteristic for the Middle Ages resulted in a dramatic reduction in the scope of surgical techniques available. A renewed interest in science, including a return to Galen’s theory and ancient surgical techniques, took place in the Renaissance. At this time, European surgeons – Ambroise Paré, Wilhelm Fabry, Jacques Guillemen and others – made ever bolder attempts at surgical treatment of breast tumour. The XVIII century witnessed further progress of medical science, while the work by William and John Hunter enabled a better understanding of structure and principles of function of the lymphatic system. The XIX century is marked by tremendous progress in surgery, including surgical treatment of malignant tumours. Introduction of ether anaesthesia in 1846 by William T. Morton, paved the way for implementation of general anaesthesia in clinical practice. Subsequent achievements of this epoch were: understanding of aseptic and antiseptic principles and examination of tissues using a microscope. The XIX century was also marked by a search of non-surgical modalities of treatment of malignant breast tumours. In 1895 Emile Grubbe was the first to use radiotherapy after mastectomy. The XX century witnessed a tremendous progress of all hitherto available diagnostic and therapeutic techniques used in the management of patients with breast cancer, particularly those based on molecular biology and gene therapy.
Autorów pracy zainteresowała historia leczenia raka piersi. Pierwsze wzmianki o występowaniu guzów piersi pojawiły się w piśmiennictwie egipskim przed trzema tysiącami lat. Etymologię określenia „rak” opisywał Paweł z Eginy, wyjaśniając, że żyły wokół guza są wypełnione i napięte niczym odnóża kraba. Lekarze epoki starożytnej nie tylko rozpoznawali tę chorobę, ale też podejmowali próby jej leczenia. Medycy rzymscy uważali, że rak piersi jest chorobą miejscową, a w leczeniu jej stosowano radykalne wycięcie guza wraz z mięśniem piersiowym. Galen, lekarz grecki, traktował raka piersi jako chorobę uogólnioną i podejmował próby leczenia zachowawczego za pomocą wyciągów ziołowych z mandragory i kapusty. Średniowiecze charakteryzowało się zahamowaniem rozwoju medycyny, co skutkowało drastycznym ograniczeniem metod leczenia chirurgicznego. Ponowny rozkwit nauk przyrodniczych, w tym także powrót do teorii Galena i technik chirurgicznych, nastąpił dopiero w epoce renesansu. W tym czasie europejscy chirurdzy - Ambroise Pare, Wilhelm Fabry, Jacques Guillemen i inni - coraz odważniej podejmowali próby operacyjnego leczenia guzów piersi. Wiek XVIII przyniósł dalszy rozwój wiedzy medycznej, a dzięki pracom Williama i Johna Hunterów poznano budowę i zasady funkcjonowania układu limfatycznego. Wiek XIX charakteryzował się szczególnymi dokonaniami w zakresie rozwoju chirurgii, w tym także guzów nowotworowych. Dzięki zastosowaniu po raz pierwszy w 1846 roku przez Williama T. Mortona anestezji eterowej wdrożono do praktyki klinicznej metody znieczulania ogólnego. Kolejnymi osiągnięciami tej epoki było poznanie zasad aseptyki i antyseptyki oraz nabycie umiejętności oceny tkanek z użyciem mikroskopu. W XIX wieku poszukiwano również innych, poza chirurgicznymi, metod leczenia złośliwych guzów piersi. W 1895 roku Emile Grubbe zastosował pierwszą radioterapię po mastektomii. Wiek XX przyniósł doskonalenie wszystkich dotychczas stosowanych metod diagnostyki i leczenia raka piersi, ze szczególnym uwzględnieniem biologii molekularnej i terapii genowej.

Źródło:

Ginekologia Onkologiczna; 2007, 5, 4; 208-217
1731-5379

Pojawia się w:

Ginekologia Onkologiczna

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 33.

Tytuł:

Fever induced oxidative stress: the effect on thyroid status and the 5-monodeiodinase activity, protective role of selenium and vitamin E

Autorzy:

Brzezinska-Slebodzinska, E.

Powiązania:

https://bibliotekanauki.pl/articles/70517.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

vitamin E
5'-monodeiodinase activity
oxidative stress
thyroid hormone
selenium

Źródło:

Journal of Physiology and Pharmacology; 2001, 52, 2
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 34.

Tytuł:

Demographic characteristics and AMH levels in rural and urban women participating in an IVF programme

Autorzy:

Kunicki, M.
Łukaszuk, K.
Liss, J.
Jakiel, G.
Skowrońska, P.

Powiązania:

https://bibliotekanauki.pl/articles/2081527.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

infertility
assisted reproductive technique
in vitro fertilization
anti mullerian hormone

Opis:

Objective. The primary aim of this preliminary study was to compare the IVF results of couples living in rural and urban areas. Additionally, the ovarian reserve parameters, such as AMH concentrations, were compared for the same groups. Materials and method. The database of 1,265 women undergoing in vitro fertilization at the Invicta Fertility Center between May 2011-July 2012 were retrospectively analyzed. Women undergoing their first assisted reproductive technology cycle with ICSI, stimulated according to the long protocol, and whose AMH levels were measured using the same DSL kit, were selected. Ultimately, 651 women were included in the study. All participants were categorized based on the area where they live: rural areas, small towns (<100,000 inhabitants) and large cities (>100,000) Results. The mean age of the patients living in large cities was significantly higher in comparison to those from rural areas and small towns. A significantly higher pregnancy body mass index (BMI) was found in women from rural areas in comparison to the women living in small and large towns. Serum AMH and inhibin B concentrations, number of ampules of gonadotropins, and antral follicle count (AFC), did not differ significantly among the groups. The study showed no significant differences among the groups in terms of clinical pregnancy rate, both per started cycle and per embryo transfer. Conclusions. No significant differences were found in IVF outcomes among the groups inhabiting rural areas, small and large cities.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 120-123
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 35.

Tytuł:

Influence of sodium nitroprusside NO-donor on psychotropic activity of angiotensin II

Autorzy:

Wisniewski, K
Holy, Z.

Powiązania:

https://bibliotekanauki.pl/articles/70848.pdf

Data publikacji:

1995

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

body temperature
sodium nitroprusside
psychomotor activity
brain
psychotropic activity
nitric oxide
pituitary hormone
rat
passive avoidance
angiotensin II
blood pressure
hormone

Źródło:

Journal of Physiology and Pharmacology; 1995, 46, 2
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 36.

Tytuł:

Developmental expression and hormonal regulation of male-specific yellow protein mRNA in adults of the desert locust, Schistocerca gregaria

Autorzy:

Begum, M.
Rahman, M.M.
Huybrechts, R.
De Loof, A.

Powiązania:

https://bibliotekanauki.pl/articles/55232.pdf

Data publikacji:

2008

Wydawca:

Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego

Tematy:

Schistocerca gregaria
yellow protein
phase transition
juvenile hormone
polymorphism
body colour
adult
yellow colouration
insulin
male
sex determination
insect
hormonal regulation
sex hormone
desert locust

Opis:

Adult males of Schistocerca gregaria turn yellow when they become sexually mature. This is due to the deposition in the cuticle of a male-specific Yellow Protein (YP), of which the amino acid sequence is known. Yellowing only happens in crowd-reared (gregarious) males, and results from the deposition of a specific ‘Yellow Protein’. If individual males (solitarious) are isolated after the adult emergence, they become sexually mature but they do not turn yellow. On the basis of a partial YP-mRNA sequence, we established a reverse transcriptase polymerase chain reaction (RT-PCR) assay to study the developmental expression of YP in crowd-reared males, isolated-reared males and females. In crowd-reared adult males the transcription of YP gene started from day 5 on, and reached a maximum at day 12. The effects of juvenile hormone (JH), insulin (bovine), corazonin, ecdysone and 20 0H-ecdysone (20E) on the regulation of YP-mRNA synthesis were also investigated. JH made the cuticle turn yellow and, as shown by RT-PCR, YP-mRNA was induced. The effect of 100 μg JHIII was stronger than that of 10 μg. Insulin was only effective in inducing YP-mRNA synthesis at high dose (19 μg) and after more days (18 d). Corazonin and 20E made the cuticle turn black, but no YP-mRNA synthesis was observed. Ecdysone (10 and 100 μg) showed no effect on body coloration and YP-mRNA. Thus, JH was found to be the most potent inducer among the hormones tested.

Źródło:

Pestycydy; 2008, 1-2; 35-41
0208-8703

Pojawia się w:

Pestycydy

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 37.

Tytuł:

Prenatal glucocorticoids can programme postnatal development

Autorzy:

Tomaszewska, E.
Dobrowolski, P.

Powiązania:

https://bibliotekanauki.pl/articles/3123.pdf

Data publikacji:

2011

Wydawca:

Instytut Medycyny Wsi

Tematy:

prenatal glucocorticoid
glucocorticoid
postnatal development
bone
dexamethasone
steroid hormone

Źródło:

Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 38.

Tytuł:

Effect of TAT-signaling fusion system along with co-expression of GroEL/ES chaperones on secretory expression of somatropin

Autorzy:

Rabbani, M.
Ghasemi, R.
Bagherinejad, M.R.
Jahanian, A.

Powiązania:

https://bibliotekanauki.pl/articles/2096995.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

chaperone
GroEL/ES
human growth hormone
somatropin
TAT system

Opis:

Human growth hormone (somatropin) is one of the most widely used recombinant proteins that stimulates growth, cell reproduction, and cell regulation in humans. Synthetic production of this protein normally results in low yields and inclusion body formation. To overcome these difficulties, the production of somatropin along with two common signal peptides, namely TorA and SufI, in co-expression with a cytosolic chaperone, GroEL/ES, was evaluated in the present study. The target protein and the two signal sequences (TorA and SufI) were synthesized and cloned into an expression plasmid (pET-22) by using Nde l and Xho l endonucleases. The expression vector (pGro7) containing chaperone proteins (GroES/EL) and one of the expression vectors containing the signal sequence (and the target protein) were co-expressed in the BL21 DE3 expression host. The results showed that although some of the expressed proteins exit the cytoplasm and enter the periplasmic space, there is also an accumulation of proteins (probably as inclusion body) inside the cytoplasmic area. Western blot analysis showed that the inclusion of a signal sequence in the cassette containing the target protein could help to secrete the protein in the periplasmic space and culture media when compared with control groups. The result of these experiments show that the TAT secretion system promotes transportation of the target protein out of the cytoplasm. This secretory system completes folding of the protein structure and transfers the mature protein to the periplasmic space.

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2020, 101, 2; 101-108
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 39.

Tytuł:

The relationship between alkaline phosphatase and bone alkaline phosphatase activity and the growth hormone/insulin-like growth factor-1 axis and vitamin D status in children with growth hormone deficiency

Autorzy:

Witkowska-Sędek, Ewelina
Stelmaszczyk-Emmel, Anna
Majcher, Anna
Demkow, Urszula
Pyrżak, Beata

Powiązania:

https://bibliotekanauki.pl/articles/1038401.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

bone formation markers
vitamin D
recombinant human growth hormone treatment
children

Opis:

The relationships between bone turnover, the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. The GH/IGF-1 axis and vitamin D can mutually modulate each other's metabolism and influence the activation of cell proliferation, maturation, and mineralization as well as bone resorption. The aim of this study was to evaluate the reciprocal associations between bone formation markers [alkaline phosphatase (ALP), bone alkaline phosphatase (BALP)], the GH/IGF-1 axis and 25-hydroxyvitamin D [25(OH)D] in children with growth hormone deficiency at baseline and during recombinant human growth hormone (rhGH) therapy. ALP, BALP, 25(OH)D and IGF-1 levels were evaluated in 53 patients included in this prospective three-year study. ALP, BALP and IGF-1 increased during rhGH therapy. Baseline ALP activity correlated positively with baseline height velocity (HV). ALP and BALP activity at 12 months correlated positively with HV in the first year of therapy. We found positive correlations between ALP and IGF-1 at baseline and during the first year of therapy, between BALP activity at 12 months and rhGH dose in the first year of therapy, and between doses of cholecalciferol in the first year of rhGH therapy and early changes in BALP activity during rhGH therapy. Our results indicate that vitamin D supplementation enhances the effect of rhGH on bone formation process, which could improve the effects of rhGH therapy. ALP and BALP activity are useful in the early prediction of the effects of rhGH therapy, but their utility as long-term predictors seemed insufficient.

Źródło:

Acta Biochimica Polonica; 2018, 65, 2; 269-275
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 40.

Tytuł:

Thyroid hormones and their receptors in the regulation of cell proliferation

Autorzy:

Puzianowska-Kuznicka, Monika
Pietrzak, Maciej
Turowska, Olga
Nauman, Alicja

Powiązania:

https://bibliotekanauki.pl/articles/1041151.pdf

Data publikacji:

2006

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

thyroid hormone nuclear receptors (TRs)
oncoproteins
triiodothyronine (T3)
proliferation
mitogens

Opis:

In the present work, we have reviewed data showing that triiodothyronine and its nuclear receptors modify expression of different genes/proteins involved in cell cycle control beginning from growth factors (such as EGF and TGF-β), to cell surface receptors (EGFR), as well as proteins acting at the cell membrane (Ras), various transcription factors (c-Fos, c-Myc, E2F1), cyclins, Cip/Kip family of cdk2 inhibitors, and p53 inhibitor Mdm2 (Table 1). We have shown how TRs are also able to modify the fate of a cell, thanks to their ability to form complexes with other transcription factors such as p53 - a key regulator of apoptosis and proliferation. Available data show that the function of thyroid hormones and of their receptors on cell proliferation is not homogenous. In fact, it strongly depends on the cell type, its developmental state (progenitor or differentiated), its patho-physiological state (normal or tumor cell), and the so-called 'cellular context'. Therefore, it is not possible to uniformly recommend T3 treatment or T3 depletion to stop or initiate proliferation of all cell types. Instead, a very individual and careful action should be considered.

Źródło:

Acta Biochimica Polonica; 2006, 53, 4; 641-650
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 41.

Tytuł:

Effect of triiodothyronine on phospholipid metabolism in skeletal muscles of the rat

Autorzy:

Zendzian-Piotrowska, M.
Gorska, M.
Dworakowski, W.
Gorski, J.

Powiązania:

https://bibliotekanauki.pl/articles/69449.pdf

Data publikacji:

2000

Wydawca:

Polskie Towarzystwo Fizjologiczne

Tematy:

abdominal aorta
phospholipid metabolism
blood
triiodothyronine
thyroid hormone
rat
skeletal muscle

Źródło:

Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910

Pojawia się w:

Journal of Physiology and Pharmacology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 42.

Tytuł:

Qa-SNARE protein SYP22 negatively regulates brassinosteroid signaling in the dark

Autorzy:

Yao, T.S.
Zhu, X.F.
Jung, J.H.
Xuan, Y.H.

Powiązania:

https://bibliotekanauki.pl/articles/19201.pdf

Data publikacji:

2015

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

SNARE protein
SYP22 gene
brassinosteroid
steroid hormone
signalling
dark
Arabidopsis

Źródło:

Acta Biologica Cracoviensia. Series Botanica; 2015, 57, 2
0001-5296

Pojawia się w:

Acta Biologica Cracoviensia. Series Botanica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 43.

Tytuł:

trans-Pro isosteres in the development of non-selective and selective mimetic agonists of insect pyrokinin neuropeptides: A review

Autorzy:

Nachman, R.J.

Powiązania:

https://bibliotekanauki.pl/articles/55206.pdf

Data publikacji:

2009

Wydawca:

Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego

Tematy:

diapause hormone
physiological process
melanization
pupariation
pheromonotropin
neuropeptide
pyrokinin family
pheromone
diapause break
pheromone biosynthesis activating neuropeptide
insect
reddish colouration hormone
peptide

Opis:

The pyrokinin (PK) family plays a multifunctional role in an array of important physiological processes in a variety of insects. A PK active core analog containing an (E)-alkene, transPro isosteric component was evaluated in five disparate PK bioassays and/or in a recombinant PK receptor cell line, representing six different insect species. The assays included pheromone biosynthesis in the moth Heliothis peltigera, melanization in the larval Spodoptera littoralis, pupariation acceleration in the larval fly Neobellieria bullata, diapause termination in the moth Heliothis zea, and hindgut contraction in the cockroach Leucophaea maderae. This constrained analog demonstrated unselective agonist activity that approached, matched, or exceeded the activity of parent PK peptides of equal length in all six PK assays. The results provide strong evidence for the orientation of Pro and the core conformation adopted by PK neuropeptides during interaction with disparate PK receptors. A PK active core analog incorporating a second transPro motif, the dihydroimidazoline moiety, was found to demonstrate pure, selective agonism in the melanotropic bioassay, with no significant activity in three other PK bioassays. Both types of transPro isosteric analogs feature modification adjacent to the primary tissue-bound peptidase hydrolysis site that is expected to enhance biostability over natural PK peptides. The research further identifies two novel scaffolds with which to design either selective or non-selective mimetic PK analogs as potential leads in the development of environmentally favorable pest management agents capable of disrupting PK-regulated systems.

Źródło:

Pestycydy; 2009, 1-4; 33-39
0208-8703

Pojawia się w:

Pestycydy

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 44.

Tytuł:

The evaluation of blood concentrations of testosterone, 17β-oestradioland anti-Muellerian hormone in dogs with cryptorchidism and testicular tumours

Autorzy:

Hornakova, L.
Vrbovska, T.
Pavl’ak, M.
Valencakova-Agyagosova, A.
Halo, M.
Hajurka, J.

Powiązania:

https://bibliotekanauki.pl/articles/2087881.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

dogs
testosterone
17β-oestradiol
anti-Muellerian hormone
stimulation test

Źródło:

Polish Journal of Veterinary Sciences; 2017, 4; 677-685
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 45.

Tytuł:

Endocrine Responses to Physical Training and Tribulus Terrestris Supplememtation in Middle-Age Men

Autorzy:

Wilk, Michał
Michalczyk, Małgorzata
Chycki, Jakub
Czuba, Miłosz
Roczniok, Robert
Gołaś, Artur
Zając, Adam
Maszczyk, Adam

Powiązania:

https://bibliotekanauki.pl/articles/1054899.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

growth hormone
insulin-like growth factor
steroidal saponins
supplementation
testosterone

Opis:

The aim of this study was to evaluate the effects of steroidal saponin supplementation on blood concentration of T, GH and IGF-1. The research involved 14 men between the age of 45 and 60 years. The duration of the experiment was 12 weeks. There were two series of laboratory tests. Independent tests were conducted at the beginning and after 12 weeks of the intervention. A two-way repeated measures ANOVA revealed a statistically significant effect of the intervention on the following variables: T-Ch (η2 = 0.542), HDL-Ch (η2 = 0.522), LDL-Ch (η2 = 0.587), T (η2 = 0.603), IGF-1 (η2 = 0.512) and GH (η2 = 0.621). Thus, FFM significantly increased while TBF and BM decreased in comparison to pre-intervention levels. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a successful form of counteracting the aging process. Nevertheless, the effects of TT supplementation on the concentration of T as well as GH and IGF-1, requires further studies, especially in middle-aged and older subjects, along with different exercise programs. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a major form of counteracting the aging process.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2016, 13, 1; 65-71
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 46.

Tytuł:

Two disulphide bridges are present in juvenile hormone binding protein from Galleria mellonella.

Autorzy:

Kołodziejczyk, Robert
Dobryszycki, Piotr
Ożyhar, Andrzej
Kochman, Marian

Powiązania:

https://bibliotekanauki.pl/articles/1044035.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

juvenile hormone binding protein
Galleria mellonella
thiol modifications
disulphide bridges

Opis:

The hemolymph juvenile hormone binding protein (JHBP) from Galleria mellonella contains two disulphide bridges/molecule and no free Cys residues. An alignment of primary structures of other Lepidopteran JHBPs indicates that Cys residues, equivalent to Cys10,17,151,195 in G. mellonellaJHBP, may be involved in -S-S- bridge formation.

Źródło:

Acta Biochimica Polonica; 2001, 48, 4; 917-920
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 47.

Tytuł:

O-GlcNAcylation, steroid hormone receptors and cancer
O-GlcNAcylacja, receptory dla steroidów i nowotwory

Autorzy:

Wilkosz, Jacek
Różański, Waldemar
Bryś, Magdalena
Forma, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1032739.pdf

Data publikacji:

2013

Wydawca:

Łódzkie Towarzystwo Naukowe

Tematy:

o-glcnacylation
steroid hormone receptors
cancer
o-glcnacylacja
receptory dla steroidów
nowotwór

Opis:

The addition of a single residue of O-linked N-acetylglucosamine (O-GlcNAc) to serine or threonine is a post-translational modification (O-GlcNAcylation) of proteins found in the cytoplasm or the nucleus. This dynamic modification is dependent on the environmental glucose concentration. O-GlcNAc modification is catalysed by a glycosyltransferase named O-linked N-acetylglucosaminyltransferase (OGT), and O-GlcNAc residue is removed by the antagonistic enzyme β-N-acetylglucosaminidase (O-GlcNAcase; OGA). Cytosolic O-GlcNAcylation is important for the proper transduction of signalling cascades, whereas nuclear O-GlcNAc is crucial for the transcriptional regulation. O-GlcNAcylation is also important in the regulation of the transcriptional activity of steroid hormone receptors. Both O-GlcNAc transferase and O-GlcNAcase are found in all tissues and have been shown to be essential for development in vertebrates, which underscores their fundamental roles in vital processes as well as in pathological conditions such as neoplastic transformation.
Glikozylacja polegająca na przyłączeniu pojedynczych reszt β-N-acetylo- D-glukozaminy do reszt seryny lub treoniny polipeptydu wiązaniem O-glikozydowym (O-GlcNAc), jest powszechną modyfikacją białek jądrowych i cytoplazmatycznych. Modyfikacja ta pozostaje w ścisłym związku z dostępnością glukozy. β-N-acetyloglukozaminylotransferaza (O-GlcNAc transferaza, OGT) jest enzymem odpowiedzialnym za katalityczne przyłączenie reszt O-GlcNAc, natomiast β-N-acetylo-D-glukozaminidaza (OGA) reszty te odłącza. Proces O-GlcNAcylacji zachodzący w cytozolu jest istotny z punktu widzenia transmisji sygnału komórkowego, natomiast przyłączanie reszt O-GlcNAc na terenie jądra wpływa na proces transkrypcji. Wykazano, że proces O-GlcNAcylacji moduluje regulację aktywności transkrypcyjnej receptorów hormonów steroidowych. Oba enzymy, O-GlcNAc transferaza i β-N-acetylo- D-glukozaminidaza wykrywane są we wszystkich tkankach i jak wykazano, niezbędne są dla prawidłowego rozwoju organizmu, jak również mogą uczestniczyć w procesie transformacji nowotworowej.

Źródło:

Folia Medica Lodziensia; 2013, 40, 1; 133-149
0071-6731

Pojawia się w:

Folia Medica Lodziensia

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 48.

Tytuł:

The content of anthocyanin in potato plants in an in vitro culture on the media with different humic products

Autorzy:

Klocek, J.
Costa, G.
Mioduszewska, H.

Powiązania:

https://bibliotekanauki.pl/articles/951217.pdf

Data publikacji:

2015

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

conference
anthocyanin content
potato plant
in vitro culture
plant hormone
humic substance

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 49.

Tytuł:

Growth hormone and growth hormone gene of the American mink (Neovison vison) – the current state of knowledge of one of the key hormones in one of the most intensively economically exploited species

Autorzy:

Skorupski, Jakub

Powiązania:

https://bibliotekanauki.pl/articles/1386056.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

American mink
growth hormone
growth hormone gene
physiological function
secretion
signal transduction
Norka amerykańska
hormon wzrostu
gen hormonu wzrostu
funkcje fizjologiczne
wydzielanie
transdukcja sygnału

Opis:

Despite the fact, that the American mink (Neovison vison) is one of the most intensively economically exploited and problematic, from the ecological point of view, fur-bearing animal, it remains one of the least studied livestock species. It can be proven by the fact, that the research on one of the key hormones, which has systemic effects, that is the growth hormone, are rather poorly advanced. The purpose of this review is to present the summary and the critical analysis of the current state of knowledge on the topic of the growth hormone in the American mink, its biological function, production in physiological conditions, regulation of secretion and transduction of the hormone’s signal. The article contains also an up to date information on the American mink growth growth hormone gene and its protein product.
Mimo że norka amerykańska (Neovison vison) jest jednym z najintensywniej eksploatowanych gospodarczo, a także problematycznych, z ekologicznego punktu widzenia, gatunków zwierząt futerkowych, pozostaje jednym z najsłabiej zbadanych gatunków zwierząt gospodarskich. Dowodzi tego, między innymi fakt, że badania nad jednym z kluczowych hormonów o działaniu systemowym, jakim jest hormon wzrostu, są słabo zaawansowane. Celem niniejszego artykułu jest przegląd i krytyczna analiza aktualnego stanu wiedzy na temat hormonu wzrostu u norki amerykańskiej, jego funkcji biologicznej, produkcji w warunkach fizjologicznych, regulacji wydzielania oraz transdukcji sygnału. Artykuł zawiera również aktualne informacje o genie hormonu wzrostu oraz jego produkcie białkowym.

Źródło:

Acta Biologica; 2017, 24; 101-132
2450-8330
2353-3013

Pojawia się w:

Acta Biologica

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce

Skocz do pozycji: 50.

Tytuł:

The effect of progesterone on oxytocin-stimulated intracellular Ca2plus mobilisation and prostaglandin secretion in porcine endometrium

Autorzy:

Kotwica, G.
Oponowicz, A.
Kurowicka, B.
Franczak, A.
Bogacka, I.

Powiązania:

https://bibliotekanauki.pl/articles/31688.pdf

Data publikacji:

2010

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

progesterone
oxytocin
intracellular calcium
calcium
prostaglandin secretion
porcine endometrium
endometrium
pregnancy
pig
hormone

Opis:

We have studied in the porcine endometrium the expression of oxytocin receptor (OTR) mRNA and the effect of progesterone (P₄) on oxytocin/oxytocin receptor (OT/OTR) function concerning intracellular Ca²⁺mobilisation ([Ca²⁺]i), prostaglandin F2α (PGF2α) and E2 (PGE2; PG) secretion. Tissue was taken from cyclic and early pregnant pigs (days 14-16). A higher expression of OTR mRNA (P<0.05) was observed in the endometrium of cyclic than pregnant pigs. The stimulatory (P<0.05) effect of OT (10⁻⁷ M) on [Ca²⁺]i mobilisation was noticed within 15-60 s and 30-60 s in endometrial stromal cells of cyclic and pregnant pigs, respectively. In the presence of P₄ (10⁻⁵ M) basal and OT-stimulated [Ca²⁺]i concentrations decreased in stromal cells during luteolysis and pregnancy. In stromal cells P₄ delayed mobilisation of [Ca²⁺]i in response to OT by 15 s during luteolysis and had no effect during pregnancy. In cyclic and pregnant epithelial cells OT stimulated mobilisation of [Ca²⁺]i in 45 s and 60 s, respectively. Oxytocin increased (P<0.05) PGF2α secretion during luteolysis and pregnancy and PGE2 during luteolysis from endometrial slices. Progesterone did not inhibit this stimulatory effect. During luteolysis OT increased (P<0.05) PGF2α in epithelial and stromal cells and PGE2 secretion in epithelial cells. In the presence of P₄ this effect of OT was reduced only in stromal cyclic cells (6 h culture). The presence of P₄ decreased the effect of OT on [Ca²⁺]i mobilisation only in stromal cells. We found that, in most conditions, P₄ did not inhibit the OT-stimulated secretion of PG in the porcine endometrium.

Źródło:

Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

Zmień widok

• na półce