- Tytuł:
-
Stabilność biologicznie aktywnych heterocyklicznych pochodnych stilbenu
The stability of biologically active heterocyclic stilbene derivatives - Autorzy:
- Kluska, Mariusz
- Powiązania:
- https://bibliotekanauki.pl/articles/1413236.pdf
- Data publikacji:
- 2021
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
konserwanty
stabilność
heterocykliczne pochodne stilbenu
stilbazole
preservatives
stability
heterocyclic stilbene derivatives
stilbazoles - Opis:
- The work concerns potential applications of stilbene derivatives as preservatives. The structure of stilbene molecule has been known since 1829. One of the most known stilbene derivatives is resveratrol. Many of derivatives synthesized so far show antimicrobial, estrogenic, antitumor and other effects. Stilbene derivatives discussed in this study show activity against 9 different microorganisms, i.e. Staphylococcus aureus 209P FDA, Streptococcus faecalis ATCC 8040, Bacillus subtilis ATCC1633, Escherichia coli PZHO 26B6, Klebsiella pneumoniae 231, Pseudomonas aeruginosa 5 Rl, Candida albicanus PCM 1409 PZH, Microsporum gypseum K1, Aspergillus fumigates Cl. The following derivatives were tested: chloride of (E)-N-(o-nitrobenzyl)-2- hydroxystilbazole-4, bromide of (E)-N-(p-bromobenzyl)-4’-hydroxystilbazole-4, bromide of (E)-N-(m-bromobenzyl)-4'-hydroxystilbazole-4, chloride of (E)-N-(p- nitrobenzyl)-4'-hydroxystilbazole-4, bromide of (E)-N-(o-bromobenzyl)-2- hydroxystilbazole-4, chloride of (E)-N-(p-chlorobenzyl)-4’-hydroxystilbazole-4. In order to determine of short- and long-term stability of six stilbene derivatives mentioned, tests were carried out using three matrices, i.e. surface water, wastewater and distilled water. Due to possible changes in time, the content of the analyzed derivatives was determined as standard in four time intervals, i.e. after 1 hour, 7 days, 28 days and 12 months. In the research, the isotachophoresis technique was used. The lowest concentrations of the analyzed derivatives were found in wastewater.
- Źródło:
-
Wiadomości Chemiczne; 2021, 75, 7-8; 997-1016
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł