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    Wyświetlanie 1-26 z 26
    Tytuł:
    Determination of serum iron levels and hemoglobin concentration in pre-weaning calves
    Autorzy:
    Geboliszova, K.
    Kadek, R.
    Illek, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1192775.pdf
    Data publikacji:
    2021
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    calves
    milk diet
    iron
    hemoglobin
    Opis:
    The aim of this study was to evaluate the serum iron (Fe) levels and hemoglobin (Hb) values in Holstein-Friesian calves with different types of milk diet. In total, 20 dairy calves (10 from each farm) were used for the experiment on two dairy farms. One farm provided the calves with a milk replacer twice a day from day 3 until weaning (farm 1), and the other one fed the calves native milk twice a day for three weeks before the milk replacer was administered (farm 2). Blood samples were collected three times, first at the age of 2-7 days, second time at the age of 30 days and last time at the age of 56 - 60 days, for the determination of iron and hemoglobin levels. Our experiment included monitoring of the occurrence of diarrheal and respiratory diseases in all calves. Values of serum iron and hemoglobin during the first sampling on farm 1: Fe 33.18 µmol l-1 (±29.39) and Hb 83.7 g l-1 (±11. 35); farm 2: Fe 8.38 µmol l-1 (±7.90) and Hb 90. 4 g l-1(±8.36). Second sampling on farm 1: Fe 37.35 µmol l-1 (±23.40) and Hb 106 g l-1 (±9.30); farm 2: Fe 5.62 µmol l-1 (±3.42) and Hb 80.3 g l-1 (±16.59). Last time on farm 1 the results were: Fe 42.69 µmol l-1 (±13.50) and Hb 101.0 g l-1 (±6.88); farm 2: Fe 32.79 µmol l-1 (±16. 07) and Hb 89.9 g l-1 (±6. 71). No respiratory diseases were observed on either farm during this study, diarrheal diseases occurred five times on farm 1 and nine times on farm 2. The results show that iron deficiency and lower hemoglobin concentration are more prevalent in animals fed whole milk.
    Źródło:
    Journal of Elementology; 2021, 26, 1; 261-270
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Plant hemoglobins can be maintained in active form by reduced flavins and confer tolerance to nitro-oxidative stress
    Autorzy:
    Sainz, M.
    Perez-Rontome, C.
    Ramos, J.
    Mulet, J.
    James, E.
    Becana, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/81132.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    plant
    hemoglobin
    nitric oxide
    nonsymbiotic hemoglobin
    flavin
    chloroplast
    thylakoid
    oxidative stress
    methyl viologen
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Flavonoids as reductants of ferryl hemoglobin
    Autorzy:
    Gebicka, Lidia
    Banasiak, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1040549.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    methemoglobin
    ferryl hemoglobin
    oxyhemoglobin
    flavonoids
    Opis:
    The ferryl derivatives of hemoglobin are products of the reactions of oxy- and methemoglobin with hydrogen peroxide. Ferryl hemoglobins, either with or without a radical site on the protein moiety, are oxidizing species. Plant polyphenols, flavonoids, have been shown to act as antioxidants in vivo and in vitro. Reactions of met- and oxyhemoglobin with hydrogen peroxide in the presence of catechin, quercetin and rutin were studied. These flavonoids accelerated reduction of ferryl hemoglobin to methemoglobin. The rate constants of the reactions of ferryl hemoglobin with catechin, quercetin and rutin were in the order of 102 M-1 s-1, i.e. similar to the rate constants of ferryl hemoglobin with intracellular reducing compounds like urate or ascorbate. The beneficial effect of flavonoids against oxidative damage of hemoglobin caused by hydroperoxides, reported in the literature, is probably, at least in part, connected with the ability of flavonoids to scavenge ferryl hemoglobin.
    Źródło:
    Acta Biochimica Polonica; 2009, 56, 3; 509-513
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparing prevalence and characteristic of anemia in children with simple versus complex febrile seizures
    Autorzy:
    Momen, Ali Akbar
    Asnafi, Ali Amin
    Nikkhah, Ali
    Reza Khalilian, Mohammad
    Mahmudi, Mohammad
    Da voodzadeh, Hannaneh
    Powiązania:
    https://bibliotekanauki.pl/articles/552868.pdf
    Data publikacji:
    2018
    Wydawca:
    Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
    Tematy:
    seizures
    febrile
    anemia
    hemoglobin
    platelet.
    Źródło:
    Family Medicine & Primary Care Review; 2018, 1; 25-28
    1734-3402
    Pojawia się w:
    Family Medicine & Primary Care Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association of glycosylated hemoglobin with mortality of patients in intensive care unit: a prospective observation study
    Autorzy:
    Kumar, Damera Seshi
    Wasnik, Seema Balkrishna
    Yadav, Amlendu
    Yadav, Rupesh
    Powiązania:
    https://bibliotekanauki.pl/articles/29432036.pdf
    Data publikacji:
    2024-03-31
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Glycated hemoglobin
    intensive care unit
    mortality
    Opis:
    INTRODUCTION: Glycated hemoglobin (HbA1c) is the most commonly used clinical test to estimate mean blood glucose during the past 2 to 3 months. In addition to diagnostic purposes, the HbA1c level also predicts diabetes complications. The aim of this study was to determine the association of glycosylated hemoglobin with mortality in intensive care unit (ICU). MATERIALS AND METHODS: A prospective observational study was conducted in the ICU with a total of 281 patients. These patients were classified into two groups based on their HbA1c levels: one group with HbA1c level < 6.5 % and another group with HbA1c level ≥ 6.5%. The following data were collected during the study period. Clinical details and scores such as the APACHE II score (Acute Physiology and Chronic Health Assessment) and daily SOFA (Sequential Organ Failure Assessment) scores for the period of stay in the ICU. ICU morbidities as the need for mechanical ventilation, the use of inotropes / vasopressors, the length of stay in the ICU, and the requirement of renal replacement therapy (RRT). The outcome measures were ICU mortality and 28-day mortality. RESULTS: Of 281 patients admitted to the ICU for more than 48 hours, 157 patients (55.9%) had HbA1c levels < 6.5%, with the remaining 124 (44.1%) had levels ≥ 6.5%. ICU mortality was present in 107 (38.07%) cases. ICU mortality was higher in patients in the HbA1c ≥ 6.5% group compared to the HbA1c < 6.5% group. This was statistically significant (p-value <0.001). Mortality at 28 days was observed in 125 (44.48%) cases. Patients with an HbA1c value ≥ 6.5%, there was a higher mortality at 28 days compared to patients with an HbA1c value < 6.5%. This was found to be statistically significant (p-value <0.001). CONCLUSIONS: The study showed that glycated hemoglobin levels (HbA1c) levels ≥ 6.5% had a significantly higher mortality rate compared to the patient in the HbA1c level < 6.5%.
    Źródło:
    Critical Care Innovations; 2024, 7, 1; 24-33
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Suplementacja żelaza u dzieci
    Iron supplementation in children
    Autorzy:
    Siudem, Paweł
    Powiązania:
    https://bibliotekanauki.pl/articles/2159079.pdf
    Data publikacji:
    2022-12
    Wydawca:
    Wydawnictwo Naukowe Medyk sp. z o.o.
    Tematy:
    żelazo
    hemoglobina
    suplementacja
    hemoglobin
    supplementation
    iron
    Opis:
    Żelazo jest jednym z ważniejszych składników mineralnych niezbędnych do prawidłowego funkcjonowania organizmu. Szczególnie istotna jest jego rola w procesie tworzenia hemoglobiny i funkcjonowaniu układu krążenia. Podczas intensywnego wzrostu u dzieci następuje wzrost zapotrzebowania na żelazo dostarczane w diecie. Postać, w jakiej jest spożywane żelazo, ma duże znaczenie dla przyswajalności. Żelazo hemowe pochodzące z produktów odzwierzęcych charakteryzuje się lepszą przyswajalnością. W przypadku problemów z dostarczaniem odpowiedniej ilości dobrze przyswajalnego żelaza można rozważyć jego suplementację.
    Iron is one of the most important minerals necessary for the proper functioning of the body. Its role in the process of hemoglobin formation and the functioning of the circulatory system is particularly important. During vigorous growth in children, the need for dietary iron increases. The form in which iron is consumed is of great importance for absorption. Heme iron derived from animal products is characterized by better digestibility. In case of problems with providing the right amount of easily digestible iron, its supplementation may be considered.
    Źródło:
    Lek w Polsce; 2022, 378, 11; 24-29
    2353-8597
    Pojawia się w:
    Lek w Polsce
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of fenugreek seed supplementation on Hemoglobin and PCV among 20-30 years old females: a pilot study
    Autorzy:
    MP, Brundha
    Powiązania:
    https://bibliotekanauki.pl/articles/2203253.pdf
    Data publikacji:
    2022-05-04
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    Anemia
    Hemoglobin
    Fenugreek supplementation
    PCV
    Hematopoietic stem cells
    Opis:
    BackgroundFemales are more likely than males to suffer from anemia. There have been many studies investigating the nutritional qualities of traditional plants. The of this study was to assess the effect of fenugreek seeds on hemoglobin and PCV values in 20-30 years old females.Material and methodsBaseline hematological tests were obtained from 10 females aged 20-30 years. Supplementation of the standard amount of fenugreek was given to the population. After 48 days the same hematological parameters were analyzed as a post-test. The results of the pre- and post-test analysis were compared by using a paired-sample t-test. Relevant details were also collected and analyzed.ResultsThe mean value of hemoglobin before supplementation (Hb1) and hemoglobin after supplementation (Hb2) was 12.3200 and 11.3300 respectively and the mean value of packed cell volume before (PCV1) and after supplementation (PCV2) was 36.7970 and 35.4700, respectively. This shows that there is a mild decrease in hemoglobin and PCV values after fenugreek supplementation, but not at a statistically significant level.ConclusionsWithin the limitations of our pilot study, we conclude that fenugreek has no significant effect on Hemoglobin and PCV values and can’t be used as an exact supplement to cure anemia.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2022, 5, 1; 27-32
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of oxygen binding by hemoglobin on the basis of mean intrinsic thermodynamic quantities
    Autorzy:
    Bordbar, Abdol-Khalegh
    Mousavi, Sayed
    Dazhampanah, Hamid
    Powiązania:
    https://bibliotekanauki.pl/articles/1041216.pdf
    Data publikacji:
    2006
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cooperativity
    mean intrinsic Gibbs free energy
    linkage phenomena
    hemoglobin
    Opis:
    The binding data for oxygenation of human hemoglobin, Hb, at various temperatures and in the absence and presence of 2,3-diphosphoglycerate, DPG, and inositol hexakis phosphate, IHP, were analyzed for extraction of mean intrinsic Gibbs free energy, ΔGo, enthalpy, ΔHo, and entropy, ΔSo, of binding at various partial oxygen pressures. This method of analysis considers all the protein species present such as dimer and tetramer forms which were not considered by Imai et al. (Imai K et al., 1970, Biochim Biophys Acta 200: 189 - 196) , in their analysis which was based on Adair equation. In this regard, the values of Hill equation parameters were estimated with high precision at all points of the binding curve and used for calculation of ΔGo, ΔHo and ΔSo were also calculated by analysis of ΔGo values at various temperatures using van't Hoff equation. The results represent the enthalpic nature of the cooperativity in Hb oxygenation and the compensation effect of intrinsic entropy. The interpretation of results also to be, into account the decrease of the binding affinity of sites for oxygen in the presence of DPG and IHP without any considerable changes in the site - site interaction (extent of cooperativity). In other words, the interactions between bound ligands, organic phosphates and oxygen, are more due to a decreasing binding affinity and not to the reduction of the cooperative interaction between sites. The results also document the more heterotropic effect of IHP compared to DPG.
    Źródło:
    Acta Biochimica Polonica; 2006, 53, 3; 563-568
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Robust Identification Approach to Individualized Anemia Model
    Autorzy:
    Akabua, E.
    Inanc, T.
    Gaweda, A.
    Brier, M. E.
    Kim, S.
    Zurada, J. M.
    Powiązania:
    https://bibliotekanauki.pl/articles/108768.pdf
    Data publikacji:
    2011
    Wydawca:
    Społeczna Akademia Nauk w Łodzi
    Tematy:
    hemoglobin
    robust identification
    Carathéodory-Fejér problem
    erythropoeitin
    anemia management
    Opis:
    Over ninety percent of End Stage Renal Disease (ESRD) patients suffer from anemia due to insufficient endogenous production of human erythropoietin. Until the advent of Recombinant Human Erythropoietin (r-HuEPO) over 30 years ago, patients with ESRD were treated mainly with multiple blood transfusions. The high cost of r-HuEPO in addition to the narrow margin between an effective do-sage and toxicity in drug administration calls for optimal dosage strategy capable of minimizing cost and toxicity while at the same time achieving the desired do-sage outcome. It is well known from control theory that a controller can be de-signed for any plant provided there is readily available a valid model for such a plant. We present Robust Identification procedure, a dimensionality reduction technique capable of capturing the inherent dynamics of anemia patients; conse-quently producing individualized model suitable for robust control synthesis and any other controller design methodologies.
    Źródło:
    Journal of Applied Computer Science Methods; 2011, 3 No. 2; 65-75
    1689-9636
    Pojawia się w:
    Journal of Applied Computer Science Methods
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparison of risk factors for low birth weight among mothers with normal and low birth weight babies
    Autorzy:
    Mugada, V.
    Kolakota, R.K.
    Sakalabathula, A.
    Kola, B.P.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087912.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Opolski. Instytut Nauk o Zdrowiu
    Tematy:
    infant
    low birth weight
    hemoglobin
    risk factors
    anemia
    India
    Opis:
    Background: Low birth weight is an alarming problem in developing countries and has severe future complications. Aim of the study: Our study aimed to compare the risk factors among mothers with low and normal birth weight babies. Material and methods: A cross-sectional study was carried out on 1000 mothers with normal and low birth weight babies (500 per group) over two years. Maternal parameters including age, hemoglobin levels, gravida, maternal weight gain, height, pregnancy-induced hypertension, etc., were collected along with anthropometric data of the child. We compared risk factors among the low and normal birth weight babies using the chi-square test, determining statistical significance at p<0.05, and high statistical significance at p<0.01. Results: Highly statistically significant associations were observed between low birth weight and seven variables: maternal age (p=0.0074), maternal height (p<0.0001), weight (p<0.0001), weight gain (p<0.0001), hemoglobin (p<0.0001), severe anemia (p<0.0001), and pregnancy-induced hypertension (p<0.0001). Conclusions: Our study observed significant modifiable risk factors like weight gain, weight, hemoglobin, and anemia among mothers with low birth weight babies. If we focus on raising awareness surrounding these risk factors, there may be an improvement in the birth weight of babies in this population.
    Źródło:
    Medical Science Pulse; 2020, 14, 2; 15-18
    2544-1558
    2544-1620
    Pojawia się w:
    Medical Science Pulse
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Środowiskowe implikacje zagospodarowania krwi poubojowej jako odpadu z przemysłu mięsnego
    Environmental implications of slaughterhouse blood disposal as waste from meat industry
    Autorzy:
    Kasprzak, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2073301.pdf
    Data publikacji:
    2017
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Mechaników Polskich
    Tematy:
    krew poubojowa
    plazma
    hemoglobina
    LCA
    slaughter blood
    plasma
    hemoglobin
    Opis:
    Przedstawiono problematykę zagospodarowania poubojowej krwi zwierzęcej (wieprzowo-wołowej i drobiowej). Scharakteryzowano podstawowe zagadnienia dotyczące powstawania i zagospodarowania poubojowej krwi zwierzęcej. Przedstawiono technologiczne możliwości wykorzystania krwi oraz jej pochodnych (plazmy krwi i hemoglobiny) w różnych gałęziach gospodarki, w tym w przemyśle paszowym. Podjęto również próbę oceny skutków takich zabiegów dla środowiska (z wykorzystaniem metody oceny cyklu życia) w porównaniu z utylizacją tej grupy odpadów.
    Problems dealing with animal slaughter blood disposal (pork- beef and poultry) are described. Key issues concerning formation and disposal of slaughter blood are characterized. Technological possibilities of using blood and its derivatives (blood plasma and hemoglobin) are demonstrated in a variety of applications, including those in feed industry. An attempt of assessment of environmental effects of such treatment using a lifecycle assessment method compared with the utilization of this waste was also performed.
    Źródło:
    Inżynieria i Aparatura Chemiczna; 2017, 5; 168--169
    0368-0827
    Pojawia się w:
    Inżynieria i Aparatura Chemiczna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A well-oxygenated cells environment may help to fight against protein glycation
    Autorzy:
    Mercier, Béatrice
    Prost, Josiane
    Prost, Michel
    Powiązania:
    https://bibliotekanauki.pl/articles/2185469.pdf
    Data publikacji:
    2011-03-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    Bol d’Air Jacquier®
    peroxidizing terpenes
    glycated hemoglobin
    oxygen
    Opis:
    Objectives: Normoglycemic Wistar rats’ Glycated Hemoglobin Levels (GHL) showed a time-dependent difference between control groups and those exposed to regular inhalation of peroxidizing extracts of turpentine. These extracts were able to optimize the oxygen permeation at the cellular level during and subsequently to a breathing session. The more the rats breathed turpentine peroxidized vapor, the lower their GHL was. This study was designed to confirm, in ex-vivo blood samples, the impact of peroxidizing extract on the GHL. Materials and Methods: Red blood cells were separated from plasmas by centrifugation. Plasmas were treated by peroxidizing and non-peroxidizing turpentine vapor or untreated (control), then combined with washed red blood cells three hours before evaluation. Glycation of hemoglobin proteins was quantified according to the Habeed’s method. Results: The ex-vivo experiments showed that the peroxidizing terpenes reduced the GHL after a three-hour contact. So did oxidized terpenes. Controls and the volatile component of the expended essential oil showed the opposite results. Conclusion: Optimal oxygenation, especially when facilitated by the peroxidized volatile component of the essential oil of turpentine, can protect organisms (mammals in this study) from protein glycation. Optimizing oxygenation can also reduce the GHL of treated blood samples after three hours of incubation.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2011, 24, 1; 102-107
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Opracowanie metody oznaczania aktywności pepsyny w soku żołądkowym
    Development of method to assay pepsin activity in gastric juice
    Autorzy:
    Krywult, Anna
    Długaszek, Michał
    Szumska, Magdalena
    Tyrpień-Golder, Krystyna
    Wielkoszyński, Tomasz
    Powiązania:
    https://bibliotekanauki.pl/articles/1037654.pdf
    Data publikacji:
    2015
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    pepsyna
    enzymy trawienne
    hemoglobina ludzka
    pepsin
    digestive enzymes
    human hemoglobin
    Opis:
    INTRODUCTION: The aim of this study was to develop a method to assay the activity of pepsin in gastric juice based on the method described in the references, which was not entirely effective in laboratory tests. The study aims to improve the aforementioned method based on the digestion of bovine hemoglobin by pepsin and to introduce effective changes so that the results may be useful for diagnostic purposes. MATERIALS AND METHODS: To achieve this, tests were carried out using the hemoglobin of different species of animals and human hemoglobin, changing the incubation periods, concentrations and volumes of reagents. RESULTS: Tests based on the use of purified (crystalline) pepsin revealed that the most effective in the assay of enzyme activity is human hemoglobin. The originally proposed incubation periods were extended, and in order to inhibit the reaction, trichloroacetic acid was used in a higher concentration than suggested, while reducing by half the volume of reactants. In the tests carried out using a purified enzyme, a correlation between the known concentration of the enzyme and the absorbance of supernatant containing the reaction products of enzymatic digestion of hemoglobin was proved. CONCLUSIONS: Introducting changes leads to more effective diagnostic use.
    WSTĘP: Celem niniejszych badań było opracowanie metody oznaczania aktywności pepsyny w soku żołądkowym na podstawie metody opisanej w piśmiennictwie, która w badaniach laboratoryjnych okazała się nie w pełni efektywna. Podjęta praca jest próbą udoskonalenia metody polegającej na trawieniu hemoglobiny wołowej przez pepsynę i wprowadzenia skutecznych zmian, aby uzyskane wyniki mogły być użyteczne w diagnostyce klinicznej. MATERIAŁ I METODY: Przeprowadzono badania z wykorzystaniem hemoglobin różnych gatunków zwierząt i człowieka, zmiany czasów inkubacji, stężeń oraz objętości reagentów. WYNIKI: Próby oparte na wykorzystaniu roztworu pepsyny wykazały, że najskuteczniejsza w oznaczaniu aktywności enzymu jest hemoglobina ludzka. Pierwotnie proponowane czasy inkubacji zostały wydłużone, a do hamowania reakcji użyto kwasu trichlorooctowego o wyższym stężeniu, niż sugerowano, równocześnie zmniejszając o połowę objęto-ści reagentów. W próbach przeprowadzonych z użyciem oczyszczonego enzymu wykazano korelację między stężeniem enzymu a absorbancją supernatantu zawierającego produkty reakcji enzymatycznego trawienia hemoglobiny. WNIOSKI: Wprowadzone modyfikacje pozwalają na udoskonalenie procesu oznaczania aktywności pepsyny w soku żołądkowym i efektywnego wykorzystania w praktyce laboratoryjnej.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2015, 69; 85-90
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of low doses of gamma rays on the stability of normal and diabetic erythrocytes
    Autorzy:
    Kaczmarska, Magdalena
    Kopyściańska, Zofia
    Fornal, Maria
    Grodzicki, Tomasz
    Matlak, Krzysztof
    Korecki, Józef
    Burda, Květoslava
    Powiązania:
    https://bibliotekanauki.pl/articles/1039830.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    γ rays
    diabetes
    absorption spectroscopy
    Mössbauer spectroscopy
    hemoglobin
    erythrocytes
    hemolysis
    Opis:
    We studied the influence of low doses of γ radiation (from 0.04 to 1.8 mGy) on the stability of human red blood cells (RBC) from healthy donors and diabetic patients using absorption spectroscopy. Because of the alteration of many enzymatic pathways in diabetic RBCs resulting in strong modification of the lipid and protein membrane components one could expect that the ionizing γ-radiation should influence the stability of the healthy and diabetic cells in a different way. Indeed, distinct discontinuities and monotonic changes of hemolysis detected in the healthy and diabetic RBCs suggest that various enzymatic and chemical processes are activated in these membranes by γ radiation. Mössbauer measurements showed that only the highest applied dose of γ radiation caused modification of hemoglobin in both types of RBCs.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 4; 489-496
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sensitivity enhancement of a wavelength interrogation-based optical fiber surface plasmon resonance sensor for hemoglobin concentration using barium titanate
    Autorzy:
    Shi, Zhen-Jiang
    Guo, Shi-Liang
    Li, Xin
    Li, Zhi-Quan
    Meng, Shu-Han
    Li, Chong-Zhen
    Powiązania:
    https://bibliotekanauki.pl/articles/27310091.pdf
    Data publikacji:
    2023
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    surface plasmon resonance
    wavelength interrogation
    barium titanate
    sensitivity enhancement
    hemoglobin concentration
    Opis:
    In this paper, the performances of a wavelength interrogation-based optical fiber surface plasmon resonance sensor for hemoglobin (Hb) concentration is investigated by theoretical simulation. The proposed configuration incorporates optical fiber, 70 nm silver, 18 nm barium titanate (BaTiO3), and 2 nm zinc oxide. Simulation results show the sensor exhibits refractive index sensitivity of 4023 nm/RIU and concentration sensitivity of 10.0873 nm/(g∙dL), along with Hb concentration varying from 0 to 14 g/dL. This paper especially focuses on the influence of BaTiO3 on the performances of the proposed sensor with light wavelength ranging from 350 to 1000 nm. Comparison analysis indicates sandwiching 18 nm BaTiO3 between sensing layers not only enhances the concentration sensitivity by 30.14% but also decreases the nonlinear error of the sensor from 0.68% to 0.63%. For a wavelength accuracy of 0.1 nm, the proposed sensor can provide a resolution of 0.0099 g/dL for Hb concentration detection.
    Źródło:
    Optica Applicata; 2023, 53, 2; 167--184
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    New generation of peptide antibiotics
    Autorzy:
    Dubin, Adam
    Mak, Paweł
    Dubin, Grzegorz
    Rzychon, Małgorzata
    Stec-Niemczyk, Justyna
    Wladyka, Benedykt
    Maziarka, Katarzyna
    Chmiel, Dorota
    Powiązania:
    https://bibliotekanauki.pl/articles/1041366.pdf
    Data publikacji:
    2005
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    staphostatin
    Staphylococcus
    virulence factor
    hemoglobin
    protease inhibitor
    hemocidins
    antimicrobial agents
    antibiotics
    Opis:
    The increasing antibiotic resistance of pathogenic bacteria calls for the development of alternative antimicrobial strategies. Possible approaches include the development of novel, broad-spectrum antibiotics as well as specific targeting of individual bacterial virulence factors. It is impossible to decide currently which strategy will prove more successful in the future since they both promise different advantages, but also introduce diverse problems. Considering both approaches, our laboratory's research focuses on the evaluation of hemocidins, broad-spectrum antibacterial peptides derived from hemoglobin and myoglobin, and staphostatins, specific inhibitors of staphopains - Staphylococcus aureus secreted proteases that are virulence factors regarded as possible targets for therapy. The article summarizes recent advances in both fields of study and presents perspectives for further development and possible applications.
    Źródło:
    Acta Biochimica Polonica; 2005, 52, 3; 633-638
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of Medicago sativa Mhb1gene expression on defense response of Arabidopsis thaliana plants
    Autorzy:
    Maassen, Anna
    Hennig, Jacek
    Powiązania:
    https://bibliotekanauki.pl/articles/1039900.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Arabidopsis thaliana
    pathogen infection
    nitrotyrosine
    nitric oxide
    peroxidase activity
    non-symbiotic hemoglobin
    Opis:
    Besides the previously described nitric oxide-detoxification activity we identified new features of class-1 non-symbiotic hemoglobin from Medicago sativa (Mhb1). Under in vitro conditions, using peroxidase in-gel activity assay, the Mhb1 protein was shown to possess also peroxidase-like activity. Due to this activity, in the presence of nitrite and hydrogen peroxide, the protein can mediate autonitration and nitration of other proteins at tyrosine residues, as revealed by tandem mass spectrometry and immune assay approaches. Mhb1 through its multifunctional activities can affect different components of signal transduction cascades operating during plant response to infections. This influence is manifested by Mhb1-mediated selective up-regulation of expression of certain pathogen inducible genes in Pseudomonas syringae infected Arabidopsis thaliana plants which overproduce Mhb1, as revealed by reverse transcription-quantitative real-time PCR analysis. Changes in expression level of these genes can influence such processes as synthesis of secondary metabolites, protein degradation and biosynthesis of ethylene. They can also result in alteration of pathogen-induced defense response of Mhb1 transgenic plants.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 3; 427-432
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The detection of specific acute phase serum protein complexes and immune complexes by Congo Red binding
    Autorzy:
    Rybarska, J
    Konieczny, L.
    Piekarska, B.
    Stopa, B.
    Roterman, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/70851.pdf
    Data publikacji:
    1995
    Wydawca:
    Polskie Towarzystwo Fizjologiczne
    Tematy:
    serum protein
    hemoglobin
    human serum
    acute phase
    Congo Red
    rabbit
    antibody
    haptoglobin
    Źródło:
    Journal of Physiology and Pharmacology; 1995, 46, 2
    0867-5910
    Pojawia się w:
    Journal of Physiology and Pharmacology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biochemiczna rewolucja, czyli rzecz o Leonie Marchlewskim i Marcelim Nenckim
    Biochemical revolution – some remarks about Leon Marchlewski’s and Marceli Nencki’s achievements
    Autorzy:
    Gryglewski, R. W.
    Powiązania:
    https://bibliotekanauki.pl/articles/172131.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    biochemia
    chemia organiczna
    chlorofil
    hemoglobina
    Marchlewski Leon
    Nencki Marceli
    biochemistry
    organic chemistry
    chlorophyll
    hemoglobin
    Opis:
    Understanding of the fundamental law and mechanisms governing the phenomenon of life is an inherent feature of human civilization. With the birth of philosophy comes first speculation about the physical conditions of life processes, which consequently will lead to the formation of the first scientific theories. Among them an important role plays the Hippocratic humoral theory. This scientific rout will be taken by the next generations of researchers seeking for the most appropriate methods and precise language of science. A significant breakthrough came in the 16th century, when Paracelsus coined his philosophical and alchemical doctrine which gives such attention to perpetual changes in living organisms, then described on the basis of transmutation. Nearly three centuries later, in the early nineteenth century the polish physician and chemist Jędrzej Śniadecki introduced the concept of metabolism, based on the principles that are present in compounds and chemical reactions. Just a dozen years later, in 1828, Wöhler`s synthesis of urea gives birth to organic chemistry. Language of chemistry has become a tool for the description of biological phenomena, slowly building up physiological chemistry which shortly was turned to biochemistry. For a young science one of the first challenges was the level of the rudimental for the living organisms dyes, which rightly appeared as essential for the understanding of the chemical nature of the phenomena of life. From that point the studies on chlorophyll (Pelletier, Caventou, Shunck, Hoppe- -Seyler) and hemoglobin (Hünefeld, Funke, Hoppe-Seyler) become crucial topic. In this pioneering studies significant, and sometimes decisive role was to be played by Polish scientists (Teichmann, Marchlewski, Nencki, Zaleski). Especially a few years’ time and very intense cooperation of Leon Marchlewski and Marcel Nencki would bring momentous decision. Marchlewski’s bold hypothesis about the chemical unity on the level of the basic dyes in plant and animal worlds was fully confirmed in the experimental procedure and the results achieved by Nencki brought the solution to the problem of the chemical structure of hemin. Joint research of Polish scientists became the foundation of modern biochemistry and had changed the biological and medical sciences so deeply, that we can talk about “biochemical revolution”. The following paper is an evaluation of the speech held by me during X National Organic Chemistry Symposium – OSCO X, Lodz, April 16–18, 2015.
    Źródło:
    Wiadomości Chemiczne; 2015, 69, 5-6; 465-477
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Haematological, blood gas and acid-base effects of central histamine-induced reversal of critical haemorrhagic hypotension in rats
    Autorzy:
    Jochem, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/71043.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Fizjologiczne
    Tematy:
    histamine
    hemoglobin
    hematocrit
    blood gas
    erythrocyte
    cardiovascular effect
    hemorrhagic hypotension
    hypotension
    hematological parameter
    rat
    Źródło:
    Journal of Physiology and Pharmacology; 2001, 52, 3
    0867-5910
    Pojawia się w:
    Journal of Physiology and Pharmacology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Technologia produkcji plazmy krwi i hemoglobiny
    Blood plasma and hemoglobin production process
    Autorzy:
    Kowalski, Z.
    Makara, A.
    Banach, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1219892.pdf
    Data publikacji:
    2011
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego. Zakład Wydawniczy CHEMPRESS-SITPChem
    Tematy:
    krew zwierzęca
    plazma
    hemoglobina
    proces technologiczny
    bilans materiałowy
    animal blood
    plasma
    hemoglobin
    technological process
    material balance
    Opis:
    Przedstawiono koncepcję technologiczną produkcji plazmy i hemoglobiny z krwi zwierzęcej opracowaną na podstawie wyników prób i testów, prowadzonych w skali laboratoryjnej i przemysłowej. Sposób prowadzenia procesu technologicznego, oraz dobór aparatów i urządzeń dla instalacji produkcyjnej zależą od asortymentu i jakości wytwarzanych produktów. W przypadku hemoglobiny, możliwe jest uzyskanie produktu ciekłego i suszonego. W przypadku plazmy, można otrzymać plazmę ciekłą, suszoną (nieodbarwioną), suszoną odbarwioną chemicznie. Bilanse materiałowe pozwoliły określić wskaźniki procesu produkcji suszonej plazmy i hemoglobiny. Sporządzono też kalkulacje kosztów produkcji, co pozwoliło na stwierdzenie opłacalności tych produkcji przy oszacowanych nakładach inwestycyjnych.
    The paper presents a concept of plasma and hemoglobin production from animal blood developed on the basis of trials and tests performed both on a laboratory and industrial scale. The production process method as well as devices and equipment selected for the production line depend on the range and the quality of products. in the case of hemoglobin it is possible to obtain liquid and dried product, while in the case plasma we can obtain liquid plasma, dried (non-decolorized) and dried chemically decolorized plasma. Material balances allow us to define the indexes for the production of dried plasma and hemoglobin. Production cost estimates have been also prepared, which allows us to show profitability for the production processes at investment outlays assumed.
    Źródło:
    Chemik; 2011, 65, 5; 466-475
    0009-2886
    Pojawia się w:
    Chemik
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Are we helping or harming our insulin-treated diabetic patients during ambulatory treatment?
    Autorzy:
    Szczesniak, G.
    Dziemidok, P.
    Paprzycki, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/50293.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    helping
    harming
    insulin-treated patient
    diabetic patient
    ambulatory treatment
    diabetes mellitus
    insulin therapy
    body weight
    hemoglobin
    knowledge
    behaviour
    Opis:
    Introduction. Correctness of insulin treatment depends on both the experience and skills of the doctor and knowledge and behaviour of the patient. Objective. Evaluation the adequacy of insulin doses administered to diabetes patients in ambulatory conditions. Material and methods. The treatment of 59 patients hospitalized in the Diabetology Ward was evaluated at admission, discharge and 3 months after hospitalization. Results. The mean daily doses of insulin significantly differed at times of evaluation and were: 53.90, 39.31 and 43.34 units, respectively (p≈0.000001). A significant reduction of body weight, 90.86 vs. 88.25 kg (p≈0.000001), was obtained only during hospitalization, and was maintained 3 months after discharge (87.86 kg). Significant differences were also noted in the body mass index (33.44 vs. 32.48 vs. 32.37 kg/m2, p≈0.000001). The change in waist circumference was not statistically significant (107.87 vs. 104.89 cm; p≈0.06). A decrease in the number of hypoglycaemia episodes was observed, but were statistically insignificant (25 vs. 23; p≈0.7). Three months after hospitalization an insignificant decrease of HbA1c level was noted (8.41% vs. 8.03%; p≈0.07). Conclusions. During treatment in the Diabetology Ward the procedure of choice was more frequently a reduction than an increase in insulin doses. This management led to the reduction of the patients’ body weight, improvement of glycaemia, without any significant effect on the diabetes control determined by the HbA1c level.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polimorfizm transferyny a plenność u owiec
    Polimorfizm transferrina i gemoglobina v sopostavlenii s oplodotvorimostyo u ovec
    Polymorphism of transferrin and hemoglobin versus fecundity of sheep
    Autorzy:
    Bojczuk, H.
    Bojczuk, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/794153.pdf
    Data publikacji:
    1988
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Tematy:
    hodowla zwierzat
    owce
    genetyka zwierzat
    polimorfizm transferyny
    polimorfizm hemoglobiny
    plennosc
    plodnosc
    animal breeding
    animal genetics
    polymorphism
    transferrin
    hemoglobin
    fecundity
    sheep
    Opis:
    Зависимость между полиморфизмом трансферрина и гемоглобина с одной и оплодотворимостыо с другой стороны исследовали в двух стадах польской низинной овцы. В стадах не установлено стетистически существенных различий в частоте рождаемости близнецов в результате спаривания овец с разными генотипами гемоглобине и происходящих от баранов с различными гемотипами.
    The dependence between the polymorphism of transferrin and hemoglobin on the one hand and fecundity on the other was investigated in two flocks of Polish lowLand sheep. No statistically significant differences in the frequency of birth Df twins after ewes and rams of different transferrin and hemoglobin genotypes aere found in any of these flocks. No significant differences were found, either, In the freuency of twin births from those of different hemoglobin genotypes and Driginating from rams of different hemotypes.
    Źródło:
    Zeszyty Problemowe Postępów Nauk Rolniczych; 1988, 352
    0084-5477
    Pojawia się w:
    Zeszyty Problemowe Postępów Nauk Rolniczych
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wahania sezonowe w zawartości hemoglobiny we krwi u dzieci szkolnych
    Sezonnye kolebanija kolichestva gemoglobina v krovi detejj shkolnogo vozrasta
    The seasonal variatons of hemoglobin content in the blood of school children
    Autorzy:
    Zahorska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/876628.pdf
    Data publikacji:
    1950
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    dzieci szkolne
    badania
    wiek
    plec
    poziom hemoglobiny
    wahania sezonowe
    wiosna
    jesien
    niedobor witamin
    school child
    research
    age
    sex
    hemoglobin level
    seasonal fluctuation
    spring
    autumn
    vitamin deficiency
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1950, 01, 3-4
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Poziom hemoglobiny, krwinek czerwonych i białka w surowicy krwi jako wskaźnik stanu odżywienia robotników zatrudnionych w przemyśle
    Uroven' gemoglobina, krasnykh krovjanykh telec i belka v syvorotke krovi kak pokazatel' sostojanija otkormlenija zavodskikh rabochikh
    Hemoglobin level, red cell number and serum proteins as indices of nutritional status in industrial workers
    Autorzy:
    Gastol, B.
    Koltek, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/875852.pdf
    Data publikacji:
    1963
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    robotnicy
    stan odzywienia
    zdrowie czlowieka
    stan zdrowotny
    poziom hemoglobiny
    krwinki czerwone
    bialka surowicy krwi
    worker
    nutritional status
    human health
    health condition
    hemoglobin level
    erythrocyte
    blood serum protein
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1963, 14, 3
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Oszacowanie dystansu genetycznego u owiec na podstawie polimorfizmu transferyn, hemoglobiny i anhydrazy węglanowej
    Ocenka geneticheskoj distancii u ovec na osnovanii polimorfizma transferrinov, gemoglobina i karbonatnoj angidrazy
    Estimation of the genetic distance in sheep on the basis of polymorphism of transferrins, hemoglobin and carbonic anhydrase
    Autorzy:
    Bojczuk, H.
    Bojczuk, B.
    Zurkowski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/797878.pdf
    Data publikacji:
    1988
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Tematy:
    owce
    populacje zwierzat
    genetyka zwierzat
    dystans genetyczny
    polimorfizm transferyny
    polimorfizm anhydrazy weglanowej
    polimorfizm hemoglobiny
    analiza filogenetyczna
    estimation
    genetic distance
    animal genetics
    animal population
    sheep
    polymorphism
    transferrin
    hemoglobin
    carbonic anhydrase
    Opis:
    На основании анализа трех полиформных систем белков ( Hb ,Tf и CA), рассматривая частоту аллелей, коэффициент гомозиготности, коэффициент „чистопородности", коэффициент сродственности и генетическую дистанцию, можно говорить о существенных генетических различиях между сравниваемыми четырьмя популяциями овец: мериносом, низинной овцой и овцой разновидности Желязна.
    The analysis of three polymorphic arrangements of proteins (Hb, Tf and CA) and consideration of the frequency of alleles, heterozygocity coefficient, "breed purity" coefficient, relation coefficient and genetic distance proved 1tie existence of significant genetic differences between the four sheep populations compared, viz.: Merino, Lowland, Wielkopolska and Żelazna sheep.
    Źródło:
    Zeszyty Problemowe Postępów Nauk Rolniczych; 1988, 352
    0084-5477
    Pojawia się w:
    Zeszyty Problemowe Postępów Nauk Rolniczych
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-26 z 26

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