Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "head and neck" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 37
Tytuł:
Zaburzenia mowy u pacjentów onkologicznych regionu głowy i szyi w diagnozie i terapii logopedycznej. Studium przypadku
Speech Disorder of the Head and Neck Regions in Diagnosis and Speech Therapy of Oncological Patients. A Case Study
Autorzy:
Buczyńska, Izabela
Powiązania:
https://bibliotekanauki.pl/articles/892731.pdf
Data publikacji:
2020-08-30
Wydawca:
Polskie Towarzystwo Logopedyczne
Tematy:
zaburzenia mowy
diagnoza i terapia logopedyczna
nowotwory regionu głowy i szyi
leczenie onkologiczne
speech disorders
diagnosis and speech therapy
head and neck tumors
oncological treatment
Opis:
Nowotwory regionu głowy i szyi to zmiany chorobowe w obrębie kompleksu ustno-twarzowego. Strukturalne i czynnościowe zaburzenia poszczególnych narządów orogardła powodują trudności w oddychaniu, połykaniu i w wymowie. Celem artykułu jest omówienie zaburzeń mowy u pacjentów onkologicznych regionu głowy i szyi po radykalnych operacjach chirurgiczno-rekonstrukcyjnych. Rodzaj zaburzeń językowych zależy od zaawansowania choroby nowotworowej, zakresu ubytku pooperacyjnego oraz indywidualnych umiejętności kompensacyjnych pacjenta. Największe odchylenia od normy występują w trakcie realizacji głosek [k, g, l, r], natomiast najsłabsze podczas fonacji samogłosek. Nadrzędnym celem logopedycznego postępowania terapeutycznego jest usprawnienie połykania, artykulacji i fonacji oraz umiejętności komunikacyjnych chorego z otoczeniem. Reedukacja czynności prymarnych i sekundarnych pacjenta onkologicznego po przebytym zabiegu rekonstrukcyjnym w obrębie twarzoczaszki sprawia, że współczesna logopedia jest integralną częścią leczenia onkologicznego.
Tumors of the head and neck region are lesions within the orofacial complex. Structural and functional disturbances of individual oropharyngeal structures cause difficulties in breathing, swallowing and pronunciation. The aim of the article is to discuss speech disorders of the head and neck regions in oncological patients after radical reconstructive surgery. The type of a linguistic disorder depends on the severity of the neoplastic disease, the extent of the postoperative loss and individual patient compensation skills. The greatest deviations from the norm occur during the implementation of sounds such as [k, g, l] and the smallest happen during phonation of vowels. The primary aim of speech therapy is to improve such skills as swallowing, articulation, phonation and communication of the patient with the environment. Re-education of the primary and secondary functions in the case of oncological patients after reconstructive surgery in the craniofacial region makes modern speech therapy an integral part of the oncological treatment.
Źródło:
Logopedia; 2019, 48, 1; 351-370
0459-6935
Pojawia się w:
Logopedia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Virtual surgical planning and cone beam computed tomography in reconstruction of head and neck tumors – pilot study
Autorzy:
Krakowczyk, Łukasz
Piotrowska-Seweryn, Agnieszka
Szymczyk, Cezary
Wierzgoń, Janusz
Oleś, Krzysztof
Ulczok, Rafał
Donocik, Karolina
Dowgierd, Krzysztof
Maciejewski, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1397270.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
cone beam computed tomography
free flap
head and neck
reconstruction
virtual surgical planning
Opis:
Introduction: The aim of the study was to prove that a combination of visual surgical planning (VSP) and cone beam computed tomography (CBCT) is an optimal technique in fibular free flap reconstructions after complex tumor resections in the head and neck region and that it leads to better functional and aesthetic outcomes. Material and method: Six patients (3 females, 3 males) with head and neck tumors were included in the study. The region concerned midface in 2 cases and mandible in 4 patients. On the basis of computed tomography of the head, fibular free flap (FFF) reconstruction was planned with the VSP technique. The 3D-printed models were prepared. At the beginning of the operation and a few minutes after the reconstruction, an xCAT CBCT by XORAN was performed. Minor corrections of the angles of the reconstructed bony parts were made where needed. The time of the operation was assessed for each case. Functional and cosmetic results were evaluated in a 1-year follow-up. Results: The mean time of operation was 6 hours and 48 minutes, which was approximately 1hour and 40 minutes less than standard reconstructive surgery. Functional recovery was achieved in all patients. Aesthetic result was unsatisfactory for 2 patients due to insufficient soft tissue masses of FFF. Conclusions: The authors claim that intraoperative CBCT imaging, regardless of the cost, improves the accuracy of aesthetic outcome of reconstructive surgeries based on VSP, especially in the region of the midface and the mandible. Further studies on a higher number of subjects are required.
Źródło:
Polish Journal of Otolaryngology; 2021, 75, 2; 28-33
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Use of 3D printing in head and neck surgery
Zastosowanie druku 3D w chirurgii głowy i szyi
Autorzy:
Likus, Wirginia
Nechoritis, Konstantinos
Różycka-Nechoritis, Aleksandra
Wilk, Renata
Hudecki, Andrzej
Gaweł, Wojciech
Przytuła-Kandzia, Katarzyna
Markowski, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1035511.pdf
Data publikacji:
2020
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
3d printing
otolaryngology
head and neck
surgery
education
reconstruction
druk 3d
otolaryngologia
głowa i szyja
chirurgia
edukacja
rekonstrukcje
Opis:
Currently, 3D printing in medicine does not comprise only prostheses or implants, but also medical modelling and surgical planning. The future of 3D printing is printing combined with tissue bioengineering (bioprinting). Scaffolds made in 3D technology containing living cells are a step to creating tissues and organs. Three-dimensional printing in surgery is now considered the future of reconstructive and regenerative medicine. Head and neck surgery also benefits from advances in 3D printing. In this article, we will describe some of the possibilities offered by 3D printing in the aspect of education, training, and printed prostheses for the needs of head and neck surgery.
Obecnie druk 3D w medycynie oznacza nie tylko protezy czy implanty, ale także modelowanie medyczne i planowanie chirurgiczne. Przyszłością będzie druk 3D połączony z bioinżynierią tkankową (bioprinting). Rusztowania wykonane w technologii 3D zawierające żywe komórki są krokiem do tworzenia tkanek i narządów. Druk trójwymiarowy w chirurgii uważany jest obecnie za przyszłość medycyny rekonstrukcyjnej i regeneracyjnej, a z dokonań na tym polu korzysta także chirurgia głowy i szyi. W prezentowanym artykule opiszemy niektóre możliwości, jakie daje druk 3D w aspekcie edukacji, szkoleń oraz drukowanych protez na potrzeby chirurgii głowy i szyi.
Źródło:
Annales Academiae Medicae Silesiensis; 2020, 74; 99-115
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Updated National Comprehensive Cancer Network guidelines for treatment of head and neck cancers 2010-2017
Autorzy:
Wierzbicka, Małgorzata
Napierała, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1398501.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
head and neck cancers treatment guidelines
biological therapy
personalized treatment
recommendations
Opis:
Introduction: The diagnostic and therapeutic recommendations have been changing over the years to improve treatment outcomes and quality of life of Head and Neck Cancer (HNC) patients. Aim: The aim of this study was to present currently recommended Head and Neck Cancer treatment guidelines based on the literature review with particular emphasis on novel approaches the NCCN algorithms. Material and methods: The review of literature covering articles published in the last five years and pointing out essential changes in HNC treatment regarding evidence based medicine. The study focused on the analysis of novel approaches for the particular primaries, the implementation of biological therapies and personalized cancer therapies. Results: Updates in the oncological NCCN guidelines for all ENT primaries except major salivary glands and subglottis are based on knowledge derived from the basic sciences, clinical trials and the best evidence available currently. The latest recommendations emphasize value of biological therapies use.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 6; 1-6
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tumor of the pharynx – an unexpected diagnosis
Autorzy:
Ura-Sabat, Katarzyna
Domka, Wojciech
Gamrot-Wrzoł, Marta
Szuber, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/454943.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
head and neck,
haemangioma
diagnosis
treatment
Opis:
Introduction. Head and neck haemangiomas occur quite rarely. These are benign lesions, often involving the pharynx and larynx. They almost always pose a diagnostic and therapeutic problem. Case description. This paper describes the case of an asymptomatic internal carotid artery aneurysm manifested by a throat tumour. A 78-year old woman with sudden deafness and vertigo was additionally diagnosed with a throat tumour. After radiological diagnosis of a haemangioma, the patient refused surgery. This article presents diagnostic methods and various types of treatments for head and neck haemangiomas. Attention was paid to the possibility of serious complications when deciding on surgical intervention of haemangiomas without a confirmed diagnosis. Conclusion. Suspicion of head and neck haemangiomas necessitates using all available diagnostic methods. The treatment plan should take into account the pace of progression, the patient’s age and co-morbid conditions. .
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 1; 78-81
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of MGMT polymorphisms rs12917 and rs11016879 in head and neck cancer risk and prognosis
Autorzy:
Kiczmer, Paweł
Prawdzic Seńkowska, Alicja
Strzelczyk, Joanna
Szydło, Błażej
Biernacki, Krzysztof
Osadnik, Tadeusz
Krakowczyk, Łukasz
Ostrowska, Zofia
Powiązania:
https://bibliotekanauki.pl/articles/1038528.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
MGMT
head and neck cancer
polymorphism
rs12917
rs11016879
Opis:
Head and neck squamous cell carcinoma (HNSCC) is one of the leading cancers by incidence worldwide. The risk of these cancers is strictly associated with alkylation factors present in tobacco smoke. The crucial role in preventing DNA alkylation is played by O6-methylguanine-DNA methyltransferase (MGMT). Dysfunction or lack of MGMT is associated with an increased risk of cancer. The aim of the study was to assess the influence of MGMT polymorphisms: rs12917 and rs11016879 on HNSCC risk and course. The study consisted of 69 HNSCC patients and 242 healthy individuals. Case samples were taken from resected tumour tissue. The control group comprised samples of epithelial cells collected from mucous membranes using swabs. DNA samples were genotyped by employing the 5' nuclease assay for allelic discrimination using TaqMan SNP Genotyping Assays. The significance between distributions of genotypes and alleles was tested using Pearson's χ2 test analysis. Our results indicated that the MGMT rs12917 TT genotype increases the risk of HNSCC. The MGMT rs11016879 AG genotype and A allele were associated with increased HNSCC risk. We noted higher risk of nodal metastasis in rs11016879 AA homozygotes. Mechanisms leading to MGMT enzymatic defect are unknown and hence further studies need to be carried out. Our data suggest that the examined polymorphisms may be considered as potential prognostic factors for HNSCC risk and outcome. Further studies are necessary to verify our results.
Źródło:
Acta Biochimica Polonica; 2018, 65, 1; 87-92
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of age and comorbidities on the outcomes of surgical treatment with free tissue transfer: a retrospective study
Autorzy:
Czesak, Małgorzata
Sobol, Maria
Bruzgielewicz, Antoni
Niemczyk, Kazimierz
Osuch-Wójcikiewicz, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1397380.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
elderly patient
head and neck cancer
reconstructive surgery
Opis:
Introduction: Microvascular free tissue transfer enables the reconstruction of complex head and neck defects. The aim of the study was to assess the results of treatment of patients undergoing reconstructive surgery and to identify factors affecting these results, with particular reference to patient’s age. Materials and Methods: All patients who underwent free-flap head and neck reconstruction in our institution between 2010 and 2017 were included in this retrospective study. A series of 66 patients met the inclusion criteria and were divided into 2 age groups: group G1 aged <65 years (n = 41) and group G2 aged ≥65 years (n = 25). Minor local complications and general complications as well as comorbidities were analyzed. Results: No correlation was found between advanced age and the risk of free flap failure as well as the incidence of local minor complications. General complications were more frequent in the G2 group (32%) than in the G1 group (19.5%), although this is not a statistically significant difference. A statistically significant difference was found between the age and the patient’s health status according to ASA (P = 0.010). In the younger low-risk group, 12 patients (29.3%) had general and local complications, while in the older low-risk group only 1 (4%). General and local complications were found in 5 (12.2%) high-risk G1 patients and in 7 (28%) high-risk G2 patients. Conclusion(s): Patients with advanced head and neck malignant tumors should undergo reconstructive microsurgery regardless of age.
Źródło:
Polish Journal of Otolaryngology; 2020, 74, 4; 8-12
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The impact of radiotherapy on the quality of life in patients with early-stage clinical head and neck cancer
Autorzy:
Milecki, Jakub
Żmijewska-Tomczak, Małgorzata
Osmola, Krzysztof
Wierzbicka, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/23203207.pdf
Data publikacji:
2021-05-07
Wydawca:
Index Copernicus International
Tematy:
head and neck cancer
Quality of life
radiotherapy
Opis:
Introduction: Radiotherapy (RT) for patients with head and neck squamous cell carcinoma (HNSCC) affects vital functions related to the irradiation volume of the head and neck region and, in addition, has a negative impact on social functioning, thereby significantly impairing patients’ quality of life (QoL). Aim: The aim of this study was to assess changes in the quality of life in patients with head and neck cancer treated with curative RT at 12 months after completion of RT. The aim of this study was to assess the differences between the baseline QoL of patients with early clinical stage HNSCC and at 12 months after curative/radical RT. Material and methods: The prospective clinical study included 92 patients in good general condition (ECOG 0–1 – Eastern Cooperative Oncology Group performance status), without regional or distant metastases, diagnosed with pathomorphologically confirmed early-stage head and neck squamous cell carcinoma treated with definitive RT. All patients participating in the study signed an informed consent form. QoL was assessed using the standard EORTC QLQ-C30 and QLQH&N35 questionnaires. In addition, information on clinical aspects and data relating to socio-demographic factors were obtained from each patient. Statistical analysis was performed using a statistical package (SPSS 17.0). T-test was used for dependent and independent samples. A general linear model was used for repeated measures. Results: Patients’ QoL deteriorated significantly after definitive RT. Worse QoL Core-30 scores in patients 12 months after the end of RT, compared with baseline QoL, before the start of RT, were observed in domains such as physical performance, fulfillment of life roles, cognitive functioning, loss of appetite, fatigue and constipation. For the QLQ-H&N35 questionnaires, patients 12 months after the end of RT reported problems in relation to aspects of life such as senses, mouth opening, dry mouth, thick saliva, pain, and weight loss. Conclusion: RT, even in early clinical stage head and neck cancer, has a negative impact on QoL, despite modern treatment techniques.
Źródło:
Polish Journal of Otolaryngology; 2021, 75, 5; 1-8
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
THE EFFECT OF NICLOSAMIDE ON THE HEAD AND NECK CARCINOMA CELLS SURVIVAL AND THE EXPRESSION OF WNT/β-CATENIN SIGNALING AND GLYCOLYSIS PATHWAY COMPONENTS
Autorzy:
Kleszcz, Robert
Paluszczak, Jarosław
Baer-Dubowska, Wanda
Powiązania:
https://bibliotekanauki.pl/articles/895272.pdf
Data publikacji:
2019-08-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Wnt signaling
glycolysis
β-catenin
niclosamide
head and neck carcinoma
Opis:
The aim of this study was to evaluate the effect of niclosamide, an antihelminthic drug recently identified as potential anti-cancer agent, on head and neck squamous carcinoma cells (HNSCC) viability, cell cycle distribution and apoptosis. The expression of key components of Wnt (CTNNB1, GSK-3β, CCND1, c-MYC, MMP7, BIRC5, Axin2) and glycolysis (GLUT1, MCT1, HK2, PFKM, PKM2, PDHA1, PDK1, LDHA) pathways was also examined to assess possible involvement in niclosamide anti-carcinogenic activity. HNSCC cells (FaDu, BICR6, H314 lines) were used in the research. Niclosamide treatment affected hypopharyngeal FaDu cells to the most extent (IC50 = 0.40 µM), while H314 cells derived from the floor of mouth were the least sensitive (IC50 = 0.94 µM). In FaDu cells the increased percentage of the cells in the S phase was observed along with the induction of apoptosis. Treatment with niclosamide in FaDu cells reduced the expression of MMP7 and the majority of glycolytic genes except increased LDHA. These results indicate that niclosamide is efficient inhibitor of HNSCC cells viability, however this effect depends on the cell type. In FaDu cells, the most sensitive to its anti-proliferative effect and prone to cell cycle arrest and apoptosis, this effect might be related to slightly modulation of canonical Wnt signaling and increased expression of LDHA.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 4; 661-669
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
THE COMPARISON OF THE EFFECTS OF PANOBINOSTAT AND PKF118-310 ON β-CATENIN-DEPENDENT TRANSCRIPTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA CELL LINES
Autorzy:
Paluszczak, Jarosław
Kleszcz, Robert
Witczak, Olga
Krajka-Kuźniak, Violetta
Powiązania:
https://bibliotekanauki.pl/articles/895659.pdf
Data publikacji:
2020-02-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Wnt signaling
head and neck cancer
panobinostat
PKF118-310
Opis:
Advanced head and neck squamous cell cancers (HNSCC) have unfavorable prognosis and new therapeutic options are necessary to improve treatment outcomes. The Wnt pathway plays an important role in the pathogenesis and progression of HNSCC. The aim of this study was to assess the effects of a histone deacetylase inhibitor – panobinostat on Wnt-dependent gene expression and on cell migration. Cell viability in HNSCC cell lines (BICR6, CAL27, FaDu, H314, SCC-25) was evaluated by MTT assay. The expression of β-catenin-target genes was assessed by qPCR and TCF/LEF-dependent reporter assay. Protein content was evaluated by Western blot. Cell migration was analyzed by the wound healing assay. Panobinostat showed differential modulation of gene expression. It reduced the level of Axin2 in CAL27 and SCC-25 cells but upregulated its expression in BICR6 and H314 cell lines. Moreover, it diminished the expression of MMP7 in BICR6, H314 and CAL27 cell lines. In contrast, the inhibitor of β-catenin transcriptional activity – PKF118-310 down-regulated the expression of β-catenin-target genes in HNSCC cell lines. Interestingly, panobinostat had opposite effects on cell migration in CAL27 and FaDu where it inhibited or stimulated migration, respectively. On the other hand, PKF118-310 reduced cell migration. The anti-cancer effects of panobinostat in HNSCC cells are rather not related to the inhibition of Wnt signaling. PKF118-310 attenuates Wnt signaling, but only in a limited number of HNSCC cell lines. Importantly, the inhibition of Wnt pathway reduces the capacity of cells for migration suggesting that it may potentially therapeutically reduce cell invasion.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 1; 77-88
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serum and saliva levels of matrix metalloproteinase 3 and 9 in pharynx and larynx cancer
Autorzy:
Polz-Dacewicz, Małgorzata
Maciąg, Paweł
Kliszczewska, Ewa
Rolniak, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/972529.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
matrix metalloproteinases
larynx cancer
throat cancer
head and neck cancer
Opis:
Introduction and objective. Matrix metalloproteinases (MMPs) are proteolytic enzymes responsible for the decomposition of extracellular matrix elements. They play an important role during embryogenesis, wound healing, endometrial epithelial exfoliation, the formation of new blood vessels, and also during cancer development. Throat and larynx tumours are included in a large group of head and neck cancers. These tumours are characterized by a poor prognosis. Despite advances in medical science, cancer treatment is difficult and often ineffective. The aim of the study was to evaluate the level of MMP-3 and MMP-9 in the serum and saliva of patients with pharynx and larynx tumours. Materials and method. Samples of saliva and serum were collected from 60 patients with larynx or throat cancer. Twenty patients without cancer comprised the control group. MMPs in saliva and serum were determined by the ELISA method. Results. In the study group, concentrations of MMP-3 in saliva were from 0.2 – 77.6 ng/ml. Patients with malignant tumours had higher saliva MMP-3 levels than healthy subjects. The concentration of MMP-3 in the serum of the study group ranged from 10.9 – 200.00 ng/ml, which was also higher than in the control group. There were no statistically significant difference in the MMP-9 level between the study and control groups (both in serum and saliva). Conclusions. This study is another element that shows the phenomena taking place at the cellular level during oncological disease. In serum and saliva samples, higher values of MMP3 were found in patients with cancer. The increase in the concentration of this enzyme in the risk group may be used for early detection of tumour transformation and evaluation of treatment.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 106-110
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Salvage surgery of hypopharyngeal cancer as a second malignancy post radiotherapy and the possibility of digestive track reconstruction – study of three cases and the literature review
Autorzy:
Rzepakowska, Anna
Jasińska, Agnieszka
Wolniewicz, Maria
Baranek, Piotr
Osuch-Wójcikiewicz, Ewa
Bruzgielewicz, Antoni
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399615.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
head and neck cancer
second primary cancer
hypopharyngeal cancer
salvage surgery
digestive tract reconstruction
radial forearm free flap
free autologous jejunal flap
Opis:
Patients with head and neck cancers have an increased risk of second malignant neoplasm occurrence (25% in long-term follow-up, 4% yearly). Most patients with a primary tumor can be treated with organ-preserving strategies including radiotherapy (RT) or chemoradiotherapy (CRT). Very often after radical surgical excision there are indications for adjuvant radiotherapy. However, if recurrence or second malignancy will develop after definitive primary RT, there are limitation to use therapeutic dose of radiation again for the same area. Salvage surgery is regarded as the only curative option in those cases. In our study we analysed 3 patients, who presented with head and neck second cancer in the area of hypopharynx, within 10-25 years after primary radiotherapy due to oropharyngeal and laryngeal cancer. A total pharyngectomy with larynx preservation and bilateral neck dissection were performed in the first case and the radial forearm free flap (RFFF) was used for reconstruction of the pharynx. Second patient, due to perilaryngeal invasion in radiological images, underwent total pharyngolaryngectomy with selective bilateral cervical lymph nodes dissection and digestive track was restored also with RFFF. The third patient had previously undergone laryngectomy and after total pharyngectomy the free autologous jejunal flap (FAJF) was used for reconstruction. The main goal of reconstruction after salvage surgery due to hypopharyngeal cancer is to reconstruct the digestive tract. The other important aspect is to optimize the anatomy for voice rehabilitation and swallowing. Unfortunately, radiation and chemotherapy impair wound healing, which indicates increased risk of postoperative complications and makes salvage surgery results unpredictable.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 1; 33-39
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review of surgical techniques for the reconstruction of the maxillofacial region used in the Department of Maxillo-Facial Surgery in Rzeszów
Autorzy:
Frańczak, Jan
Pakla, Paweł
Brodowski, Robert
Stopyra, Wojciech
Burdzy, Danuta
Lewandowski, Bogumił
Powiązania:
https://bibliotekanauki.pl/articles/454921.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
reconstructive surgery
microsurgery
surgical flaps
cancer of head and neck
Opis:
Postoperative reconstruction of tissue loss within the head and neck after extensive resections due to malignant neoplasms or traumas has always been a challenge for maxillo-facial surgeons or ENT physicians. Due to the complex anatomical structure of the head and neck region, every patient requires an individual approach and there is no standard method of management appropriate for all patients. The number of patients treated for malignancy is increasing year by year. The possibility of performing extensive resections in the head and neck region are conditioned by appropriate reconstruction. Aim. The aim of the paper is to present the reconstructive methods used in the Clinical Department of Maxillofacial Surgery, F. Chopin Hospital No. 1 in Rzeszow. A short review of the most commonly used flaps is presented, taking into account their advantages, disadvantages and surgical technique in terms of their usefulness in daily clinical practice.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 3; 273-278
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention
Autorzy:
Kowalski, Andrzej
Olszewski, Jurek
Zielińska-Bliźniewska, Hanna
Powiązania:
https://bibliotekanauki.pl/articles/1397748.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
Head and Neck Cancer Prophylaxis Program
oral cavity
oropharynx cancer
risk factors
Opis:
Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 6; 24-31
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Report from the analysis of implementiation of 4th Head and Neck Cancer Awareness Week in Department of Otolaryngology in Międzyleski Hospital in Warsaw
Autorzy:
Dżaman, Karolina
Piskadło–Zborowska, Karolina
Pietniczka–Załęska, Mirosława
Powiązania:
https://bibliotekanauki.pl/articles/1398499.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
European Head and Neck Cancer Awareness Week
head and neck tumors
Opis:
Introduction: The aim of the study was to analyze the profile of patients who reported for free screening examinations during the 4th European Head and Neck Cancer Awareness Week to the Department of Otolaryngology, Miedzylesie Specialist Hospital, Warsaw, Poland. Material and methods: We enrolled 225 patients, aged 26-92 years (mean, 63 years). There were 149 women (66%) and 76 men (34%). All patients filled out a survey regarding risk factors of head and neck cancer (HNC), including symptoms and lifestyle characteristics. Subsequently, all participants underwent a complete laryngological examination. Results: Among the studied patients, we found the following lifestyle-related risk factors of HNC: tobacco use (22%), alcohol use more than 1 time per week (12%), oral sex (17%), multiple sexual partners (10%), rare dental checkups (24%), and dental prostheses (45%). The most frequent symptoms that prompted the patients to report for screening exams were as follows: chronic hoarseness (64%), xerostomia (39%), dysphagia (37%), nasal congestion (6%), and neck tumor (5%). Further imaging studies were ordered in 15 patients (7%), fiberoscopy in 25 (11%), and lesion excision in 18 (8%). Among the studied patients, 17 were referred for further oncological treatment, of whom 14 had benign tumors and 4 malignant tumors. Conclusions: The Head and Neck Cancer Awareness campaign increased the awareness of HNC, and it should systematically encompass people at increased risk. By implementing this program in our department, we were able to detect and initiate early treatment in 7.5% of the screened people. However, appropriate workup and treatment require funding and therefore systemic measures should be taken to enable a wide implementation of such screening programs.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 6; 35-39
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 37

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies