- Tytuł:
- Transport of organic anions by multidrug resistance-associated protein in the erythrocyte.
- Autorzy:
-
Rychlik, Błażej
Pułaski, Łukasz
Sokal, Adam
Soszyński, Mirosław
Bartosz, Grzegorz - Powiązania:
- https://bibliotekanauki.pl/articles/1044320.pdf
- Data publikacji:
- 2000
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
glutathione S-conjugates
erythrocyte
multidrug resistance-associated protein
glutathione
transport - Opis:
- The active transport of oxidized glutathione and glutathione S-conjugates has been demonstrated for the first time in erythrocytes and this cell remained the main subject of research on the "glutathione S-conjugate pump" for years. Further studies identified the "glutathione S-conjugate pump" as multidrug resistance-associated protein (MRP). Even though cells overexpressing MRP and isolated MRP provide useful information on MRP structure and function, the erythrocyte remains an interesting model cell for studies of MRP1 in its natural environment, including the substrate specificity and ATPase activity of the protein.
- Źródło:
-
Acta Biochimica Polonica; 2000, 47, 3; 763-772
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł