- Tytuł:
- The alterations in genetic apparatus of somatic and generative cells of the host caused by helminths metabolites
- Autorzy:
- Bekish, V J
- Powiązania:
- https://bibliotekanauki.pl/articles/838630.pdf
- Data publikacji:
- 2001
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
metabolite
alteration
mice
cell
helminth
host
generative cell
mouse
bone marrow
testicle
Ascaris suum
genetic apparatus
somatic cell
Hymenolepis nana
Toxocara canis - Opis:
- Alterations in the genetic apparatus of mice bone marrow cells and testicles caused by Hymenolepis nana, Ascaris suum and Toxocara canis metabolites have been investigated by means of micronuclear test application. The activity of spermatogenesis has been investigated at experimental hymenolepidosis, migrating ascariasis and toxocarosis with the use of ³H-timidine. Helminths metabolites have been established to exert a mutagenie effect on somatic cells of bone marrow, spermatogonies and also on the generative cells (spermatides) of helminths in invaded mice. The concurrent increase in micronucleus number in erythrocytes, spermatogonies and in spermatides (to a lesser degree) of invaded mice has been revealed. The decrease in spermatogenesis activity has been established in experimental hymenolepidosis, migrating ascariasis and toxocarosis in invaded mice.
- Źródło:
-
Annals of Parasitology; 2001, 47, 4
0043-5163 - Pojawia się w:
- Annals of Parasitology
- Dostawca treści:
- Biblioteka Nauki
Artykuł