Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "filaments" wg kryterium: Temat

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-8 z 8
    Tytuł:
    Effect of Solublising Aids on The Entrapment of Loratidine in Pre-Fabricated PVA Filaments Used for FDM Based 3D-Printing
    Autorzy:
    Mahmood, Faisal
    Hussain, Amjad
    Arshad, Muhammad Sohail
    Abbas, Nasir
    Irfan, Muhammad
    Qamar, Nadia
    Hussain, Fahad
    Ghori, Muhammad Usman
    Powiązania:
    https://bibliotekanauki.pl/articles/895332.pdf
    Data publikacji:
    2020-02-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    3D printing
    Plasticizers
    Fused deposition modelling (FDM)
    PVA filaments
    Solubilizers
    Opis:
    Low drug loading efficiency is the limiting factor in the use of pre-fabricated filaments for 3D printing of pharmaceuticals. The aim of present study was to modify the material properties of pre-fabricated filament by incorporating the suitable solubilizing aids in order to enhance the drug loading efficiency. Loratadine was loaded into PVA filaments by using solubilizers (Soluplus®, Sodium lauryl sulphate) and plasticizers (glycerin and Polyethylene glycol-400) and the printability of filaments was investigated. The treated filaments were characterized for morphology and diameter changes, drug content, FTIR and thermal properties and printed into tablets of suitable dimensions. The printed tablets were also characterized for drug assay and drug release. The results have shown that the surface of different drug loaded filaments become rough with almost no change in diameter hence, these filaments remained printable. However, there was 7 to 24 times enhancement in drug content of filaments treated with particularly those pretreated with glycerin and soaked in drug solution containing Soluplus. The printed tablets have also shown almost similar drug content as their precursor filaments and the release followed diffusion mechanism in most of the formulations. The study concludes that the treatment of PVA filament with solubilizer aids has significantly improved the drug loading entrapment without compromising the printability.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 1; 175-182
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polyurethanes as a Potential Medical-Grade Filament for Use in Fused Deposition Modeling 3D Printers – a Brief Review
    Poliuretany jako potencjalnefilamenty klasy medycznej do druku 3D w technologii Fused Deposition Modeling (FDM) – krótki przegląd literatury
    Autorzy:
    Przybytek, A.
    Gubańska, I.
    Kucińska-Lipka, J.
    Janik, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/234343.pdf
    Data publikacji:
    2018
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
    Tematy:
    medical-grade polyurethanes
    filaments
    Fused Deposition Modeling
    FDM
    3D printing
    medyczne poliuretany
    filamenty
    modelowanie osadzania stopionego
    drukowanie 3D
    Opis:
    The possibility of using 3D printing technology (3DP) in medical field is a kind of revolution in health care. This has contributed to a rapid growth in demand for 3D printers, whose systems and materials are adapted to strict medical requirements. In this paper, we reporta brief review of polyurethanes as a potential medical-grade filament for use in Fused Deposition Modeling (FDM) 3D printer technology. The advantages of polyurethanes as medical materials and the basic operating principles of FDM printers are presented. The review ofpresent solutions in the market and literature data confirms the large interest in 3D printing technologies for the production of advanced medical devices. In addition, it is shown that thermoplastic-elastomer polyurethanes may be an effective widespread class of material inthe market as thermoplastic filament for FDM 3D printers.
    Możliwość stosowania technologii druku 3D (3DP) do zastosowań w medycynie stanowi swego rodzaju rewolucję w służbie zdrowia. Przyczyniło się to do znaczącego wzrostu zapotrzebowania na nowe drukarki oraz materiały, które są dostosowane do wymagań medycznych. W artykule przedstawiono zalety materiałów poliuretanowych, które mogą znaleźć zastosowanie jako filamenty klasy medycznej do druku 3D w technologii Fused Deposition Modeling (FDM). Opisano również podstawowe zasady działania drukarek FDM. Przegląd dostępnych rozwiązań przemysłowych oraz doniesień literaturowych potwierdził słuszność stosowania technologii druku 3D do produkcji spersonalizowanych wyrobów medycznych, wskazując jednocześnie na niewystarczającą liczbę dostępnych certyfikowanych biomedycznych materiałów dedykowanych tej technologii.
    Źródło:
    Fibres & Textiles in Eastern Europe; 2018, 6 (132); 120-125
    1230-3666
    2300-7354
    Pojawia się w:
    Fibres & Textiles in Eastern Europe
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Thermoplastic elastomer filaments and their application in 3D printing
    Termoplastyczne włókna elastomerowe i ich zastosowanie w druku 3D
    Autorzy:
    Przybytek, A.
    Kucińska-Lipka, J.
    Janik, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/272636.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Inżynierii Materiałów Polimerowych i Barwników
    Tematy:
    3D printing
    flexible filaments
    thermoplastic elastomer
    TPE
    thermoplastic polyurethane
    TPU
    druk 3D
    włókna elastyczne
    elastomer termoplastyczny
    termoplastyczny poliuretan
    Opis:
    The paper provides an overview on the materials used in the 3D printing technology (the Polish and foreign market) with a particular focus on flexible filaments and their possible application in the industry. There are described the techniques of 3D printing and modern filaments available on the market. There is observed the increase of interest in the production of products from filaments based on thermoplastic elastomers (TPE), including the applications in the electronics and medicine, especially in tissue engineering. Ability to modify the physical and mechanical properties of thermoplastic elastomers, combined with their unique elastic and processability properties, opens new possibilities for engineers, designers and bio-engineers. The possibility to use new materials in 3D printing can contribute to faster development of research and accelerates implementation of innovative products.
    Praca stanowi przegląd dostępnych na rynku krajowym i zagranicznym materiałów używanych w technologii druku 3D. Szczególną uwagę poświęcono elastycznym włóknom (ang. flexible filaments) oraz ich potencjalnemu zastosowaniu w przemyśle. Przedstawiono i oceniono stosowane technologie druku 3D. Scharakteryzowano nowoczesne włókna kompozytowe, ich właściwości i zastosowanie. Opisano także najnowsze doniesienia literaturowe związane z otrzymywaniem nowoczesnych termoplastycznych elastomerów (TPE) do wykorzystania w technologii druku 3D. Na podstawie przeanalizowanych publikacji zauważono ogromny wzrost zainteresowania wykorzystaniem termoplastycznych poliuretanów (TPU) w przemyśle elektronicznym, medycznym oraz obuwniczym. Dostępne na rynku nowoczesne produkty wykonane przy użyciu drukarek 3D z wykorzystaniem TPU, potwierdzają te doniesienia. Interesujące jest wykorzystanie wodnych dyspersji TPU z możliwą kontrolą bioaktywności do zastosowań w inżynierii tkankowej. Dodatek do wodnych dyspersji TPU, biopolimerów lub poli(tlenku etylenu) (PEO) powoduje znaczny wzrost ich lepkości. Pozwala to na użycie tego materiału w drukarkach 3D w technologii niskotemperaturowego drukowania (LFDM). Możliwość kontrolowanej zmiany właściwości fizycznych i mechanicznych, wyjątkowa elastyczność, trwałość oraz łatwość przetwórstwa termoplastycznych elastomerów otwierają nowe możliwości wykorzystania druku 3D. Dzięki temu technologia ta przestaje być narzędziem jedynie do prototypowania – umożliwia ona drukowanie materiałów gotowych do użytku na skalę przemysłową.
    Źródło:
    Elastomery; 2016, 20, 4; 32-39
    1427-3519
    Pojawia się w:
    Elastomery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Recent measurements of soft X-ray emission from the DPF-1000U facility
    Autorzy:
    Surała, W.
    Sadowski, M. J.
    Paduch, M.
    Zielinska, E.
    Tomaszewski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/148171.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    plasma focus
    X-ray emission
    X-ray images
    gas puffing
    filaments
    hot spots
    Opis:
    Soft X-ray imaging is a very useful diagnostic technique in plasma-focus (PF) experiments. This paper reports results of four experimental sessions which were carried out at the DPF-1000U plasma-focus facility in 2013 and 2014. Over 200 discharges were performed at various experimental conditions. Measurements were taken using two X-ray pinhole cameras with a line of sight perpendicular to the z-axis, at different azimuthal angles (about 20° and 200°), and looking towards the centre of the PF-pinch column. They were equipped with diaphragms 1000 μm or 200–300 μm in diameter and coated with filters of 500 μm Al foil and 10 μm Be foil, respectively. Data on the neutron emission were collected with silver activation counters. For time-resolved measurements the use was made of four PIN diodes equipped with various fi lters and oriented towards the centre of the PF-column, in the direction perpendicular to the electrode axis. The recorded X-ray images revealed that when the additional gas-puff system is activated during the discharge, the stability of the discharge is improved. The data collected in these experiments confi rmed the appearance of a filamentary fi ne structure in the PF discharges. In the past years the formation of such fi laments was observed in many Z-pinch type experiments. Some of the recorded X-ray images have also revealed the appearance of the so-called hot- -spots, i.e. small plasma regions of a very intense X-ray emission. Such a phenomenon was observed before in many PF experiments, e.g. in the MAJA-PF device, but it has not been investigated so far in a large facility such as the DPF-1000U. The time-resolved measurements provided the evidence of a time lapse between the X-ray emission from plasma regions located at different distance from the anode surface. The formation of distinct ‘hot-spots’ in different instants of the DPF-1000U discharge was also observed.
    Źródło:
    Nukleonika; 2015, 60, 2; 303-308
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The impact of toothbrush filament design on gingival health during healing. A randomized, controlled, investigator-blinded clinical trial
    Autorzy:
    Kovalova, E.
    Novak, B.
    Klamarova, T.
    Eliasova, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2052459.pdf
    Data publikacji:
    2015
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    conical filaments
    toothbrush
    gingival health
    gingival abrasion
    healing
    Opis:
    Objectives. The primary objective of the study was to test toothbrushes with different types of filaments (conical vs. rounded) with respect to cause gingival abrasion after surgical intervention of wisdom teeth. A secondary objective was to evaluate the efficacy of plaque removal and the improvement of gingival conditions to alleviate wound healing and to avoid gingivitis. Methods. One hundred and seventy-three healthy subjects with surgical intervention of wisdom teeth participated in a randomized, single blind study and were randomly allocated to control group (standard ADA reference toothbrush) or test group (meridol® special toothbrush with conical filaments). Clinical examinations included gingival abrasion, plaque index and gingival index, and were conducted at baseline, 7 and 28 days. Results. For the gingival abrasion the mean number of lesions of all sizes was after 28 days significantly lower in the test group (p-value <0.001) compared to control group. Plaque index was not significantly different between the two groups in the last visit. At day 28 the gingival index was significantly lower in the test group (p=0.031) compared to control group. Conclusions. The toothbrush with conical filaments induced significantly less gingival abrasions than the standard ADA toothbrush and showed superior results in improving gingival health (gingival index). Both toothbrushes were comparable effective with respect to plaque removal. Clinical Relevance. Scientific rationale for study: Supra and sub-gingival biofilm leads to gingival inflammation. Post-surgical removal of the biofilm from gingival surfaces promotes healing after wisdom tooth extraction. Tooth brushing leads to gingival abrasion. Earlier investigations with toothbrushes having conical filaments suggest less gingival tissue damage. Principal findings: The results showed that the toothbrush with conical filaments caused significantly less gingival abrasions than the toothbrush with rounded filaments. Practical implications: Toothbrush filament design should be considered when choosing toothbrush for oral hygiene after oral surgery.
    Źródło:
    Health Problems of Civilization; 2015, 09, 1; 47-53
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The role of actin and microtubule networks in plasmid DNA intracellular trafficking
    Autorzy:
    Ondřej, Vladan
    Lukášová, Emilie
    Falk, Martin
    Kozubek, Stanislav
    Powiązania:
    https://bibliotekanauki.pl/articles/1041059.pdf
    Data publikacji:
    2007
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cytoplasmic trafficking
    microtubules
    plasmid DNA-lipid complexes
    actin filaments
    Opis:
    This work is focused on the function of the microtubule and actin networks in plasmid DNA transport during liposomal transfection. We observed strong binding of plasmid DNA-lipid complexes (lipoplexes) to both networks and directional long-range motion of these lipoplexes along the microtubules. Disruption of either of these networks led to the cessation of plasmid transport to the nucleus, a decreased mobility of plasmids, and accumulation of plasmid DNA in large aggregates at the cell periphery. Our findings show an indispensable but different role of both types of cytoskeleton, actin and microtubular, in the processes of gene delivery.
    Źródło:
    Acta Biochimica Polonica; 2007, 54, 3; 657-663
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Reconstitution of ventricular myosin with atrial light chains 1 improves its functional properties.
    Autorzy:
    Khalina, Yana
    Bartsch, Holger
    Petzhold, Daria
    Haase, Hannelore
    Podlubnaya, Zoya
    Shpagina, Mila
    Morano, Ingo
    Powiązania:
    https://bibliotekanauki.pl/articles/1041425.pdf
    Data publikacji:
    2005
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    myosin light chains
    cardiac myosin
    dilated cardiomyopathy
    myosin filaments
    reconstituted myosin
    actin-activated ATPase activity
    Opis:
    Atrial light chain 1 (ALC-1) is expressed in embryonic and hypertrophied human ventricles but not in normal adult human ventricles. We investigated the effects of recombinant human atrial light chains (hALC-1) on the structure and enzymatic activity of synthetic filaments of ventricular myosin. The endogenous ventricular myosin light chain 1 (VLC-1) was partially replaced by recombinant hALC-1 yielding hALC-1 levels of 12%, 24% and 42%. This reconstitution of ventricular myosin with hALC-1 did not change the length of synthetic myosin filaments but led to more rounded myosin heads in comparison with those of control filaments. Actin-activated ATPase activity of myosin, a parameter of functional activity of molecular motor, amounted to 79.5 nmol Pi/mg per min in control myosin filaments. Reconstitution with hALC-1 caused a profound increase of the actin-activated myosin ATPase activity in a dose dependent manner, for example, synthetic myosin filaments formed with 12%, 24% and 42% hALC-1 reconstituted myosin revealed the actin-activated ATPase activity increased by 18%, 26% and 36%, respectively, as compared to control. These results strongly suggest that in vivo expression of ALC-1 enhances ventricular myosin function, thereby contributing to cardiac compensation.
    Źródło:
    Acta Biochimica Polonica; 2005, 52, 2; 443-448
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Order-disorder structural transitions in synthetic filaments of fast and slow skeletal muscle myosins under relaxing and activating conditions.
    Autorzy:
    Podlubnaya, Zoya
    Malyshev, Sergey
    Nieznański, Krzysztof
    Stępkowski, Dariusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1044221.pdf
    Data publikacji:
    2000
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    method of slow skeletal muscle myosin preparation.
    Ca2+-induced structural transitions
    myosin filaments
    fast and slow skeletal muscle myosin
    Opis:
    In the previous study (Podlubnaya et al., 1999, J. Struc. Biol. 127, 1-15) Ca2+-induced reversible structural transitions in synthetic filaments of pure fast skeletal and cardiac muscle myosins were observed under rigor conditions (-Ca2+/+ Ca2+). In the present work these studies have been extended to new more order-producing conditions (presence of ATP in the absence of Ca2+) aimed at arresting the relaxed structure in synthetic filaments of both fast and slow skeletal muscle myosin. Filaments were formed from column-purified myosins (rabbit fast skeletal muscle and rabbit slow skeletal semimebranosus proprius muscle). In the presence of 0.1 mM free Ca2+, 3 mM Mg2+ and 2 mM ATP (activating conditions) these filaments had a spread structure with a random arrangement of myosin heads and subfragments 2 protruding from the filament backbone. Such a structure is indistinguishable from the filament structures observed previously for fast skeletal, cardiac (see reference cited above) and smooth (Podlubnaya et al., 1999, J. Muscle Res. Cell Motil. 20, 547-554) muscle myosins in the presence of 0.1 mM free Ca2+. In the absence of Ca2+ and in the presence of ATP (relaxing conditions) the filaments of both studied myosins revealed a compact ordered structure. The fast skeletal muscle myosin filaments exhibited an axial periodicity of about 14.5 nm and which was much more pronounced than under rigor conditions in the absence of Ca2+ (see the first reference cited). The slow skeletal muscle myosin filaments differ slightly in their appearance from those of fast muscle as they exhibit mainly an axial repeat of about 43 nm while the 14.5 nm repeat is visible only in some regions. This may be a result of a slightly different structural properties of slow skeletal muscle myosin. We conclude that, like other filaments of vertebrate myosins, slow skeletal muscle myosin filaments also undergo the Ca2+-induced structural order-disorder transitions. It is very likely that all vertebrate muscle myosins possess such a property.
    Źródło:
    Acta Biochimica Polonica; 2000, 47, 4; 1007-1017
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies