- Tytuł:
- Protection of cattle against bovine leukemia virus (BLV) infection could be attained by DNA vaccination
- Autorzy:
-
Brillowska, Anna
Dąbrowski, Sławomir
Rułka, Jan
Kubiś, Piotr
Buzała, Ewa
Kur, Józef - Powiązania:
- https://bibliotekanauki.pl/articles/1044457.pdf
- Data publikacji:
- 1999
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
DNA vaccine
env gene
expression plasmid
immunization - Opis:
- The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge (500 BLV-infected lymphocytes as an infectious dose).
- Źródło:
-
Acta Biochimica Polonica; 1999, 46, 4; 971-976
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł