- Tytuł:
- Substrate inhibition in lipase-catalysed transesterification of mandelic acid with vinyl acetate
- Autorzy:
-
Dąbkowska, K.
Pilarek, M.
Szewczyk, K. W. - Powiązania:
- https://bibliotekanauki.pl/articles/185294.pdf
- Data publikacji:
- 2012
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Tematy:
-
kinetic resolution
enantiomers
kinetic model
lipase
substrate inhibition
rezolucja kinetyczna
enancjomery
model kinetyczny
lipazy
inhibicja substratem - Opis:
- Kinetic resolution of (R)- and (S)-mandelic acid by its transesterification with vinyl acetate catalysed by Burholderia cepacia lipase has been studied. The influence of the initial substrate concentration on the kinetics of process has been investigated. A modified ping-pong bi-bi model of enzymatic transesterification of (S)-mandelic acid including substrate inhibition has been developed. The values of kinetic parameters of the model have been estimated. We have shown that the inhibition effect revealed over a certain threshold limit value of the initial concentration of substrate.
- Źródło:
-
Chemical and Process Engineering; 2012, 33, 4; 539-546
0208-6425
2300-1925 - Pojawia się w:
- Chemical and Process Engineering
- Dostawca treści:
- Biblioteka Nauki
Artykuł