Skocz do pozycji: 1.

Tytuł:

Therapeutic options in the treatment of open angle glaucoma and their use in accordance with the latest guidelines

Autorzy:

Misiuk-Hojło, Marta
Tomczyk-Socha, Martyna

Powiązania:

https://bibliotekanauki.pl/articles/51789554.pdf

Data publikacji:

2024-03-31

Wydawca:

Medical Education

Tematy:

glaucoma
pharmacological therapy
glaucoma drugs
combined drugs

Opis:

Glaucoma is an optic neuropathy characterized by typical damage of the optic nerve with gradual atrophy of retinal ganglion cells and visual field defects. The goal of glaucoma therapy is to reduce intraocular pressure and reduce daily pressure fluctuations. Currently, in the treatment of primary open-angle glaucoma in Poland, we use four groups of drugs: β-adrenergic receptor antagonists, prostaglandin analogues, α-adrenergic receptor agonists and carbonic anhydrase inhibitors. First-line drugs, according to the guidelines of the Polish Ophthalmological Society, are prostaglandin analogues/prostamide. When considering the addition of a second drug to prostaglandins, brimonidine lowers intraocular pressure more strongly than dorzolamide or brinzolamide, similarly as timolol does. Drug containing two active substances are as effective as substances administered in two separate drops, therefore it is advantageous to use combined drug instead of using two different drugs.

Źródło:

OphthaTherapy; 2024, 11, 1; 7-13
2353-7175
2543-9987

Pojawia się w:

OphthaTherapy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

Monitoring risk behaviour in adolescent pupils regarding consumption of psychoactive substances

Autorzy:

Wojtyła-Buciora, Paulina
Klimberg, Aneta
Kapka-Skrzypczak, Lucyna Kapka-Skrzypczak
Diatczyk, Jarosław
Urbaniak, Monika
Ulatowska-Szostak, Ewa
Bołdowski, Tomasz
Wojtyła, Andrzej
Marcinkowski, Jerzy T.

Powiązania:

https://bibliotekanauki.pl/articles/989849.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

drugs/narcotics
designer drugs (dds)/legal highs
adolescents/youth

Opis:

Introduction. Taking psychoactive substances constitutes a significant problem for Public Health, particularly in preventing drug abuse and addiction. Objectives. To estimate the amount and incidence of drug consumption in middle and high school pupils, including the circumstances in which drug taking first started, and to determine pupils’ knowledge about the consequences of taking psychoactive substances and designer drugs (DDs). Materials and methods. A randomised study was conducted throughout Poland on 9,360 pupils attending middle school (junior high school) in 2009 and 7,971 pupils from middle and high school pupils in 2011. The survey consisted of a questionnaire devised by the Chief Sanitary Inspectorate (GIS) and the replies obtained were subject to the relevant statistical analyses. Results. Drug taking was found to have increased between 2009–2011, especially among those attending high school; proportionally rising from 4% – 11%. The numbers who had ever taken designer drugs were 3% for middle school pupils and 4% from high school. Conclusions. 1) Adolescent drug consumption has increased, particularly in those of older age and in boys. 2) Despite the only brief interval for which designer drugs were legal, they have gained high popularity among the young. 3) Adolescents have insufficient knowledge about the dangers of using DDs. 4) Faced with the growing threat of a dynamic designer drug market, appropriate counter-measures in education and prevention are therefore necessary.

Źródło:

Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

New applications of FeMOF as drug delivery system for theophylline

Autorzy:

Strzempek, W.
Gil, B.
Menaszek, E.

Powiązania:

https://bibliotekanauki.pl/articles/285613.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

theophylline
drugs
MOF

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 106
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Potential of electrospinning technique to drug delivery system

Autorzy:

Dzierzkowska, E.
Stodolak-Zych, E.

Powiązania:

https://bibliotekanauki.pl/articles/284071.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

electrospinning
drugs
fibers

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 119
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Halloysite nanotubes as potential carrier for gentamicin

Autorzy:

Stodolak-Zych, E.
Skóra, K.
Rapacz-Kmita, A.
Mikołajczyk, M.
Gajek, M.
Bućko, M. M.

Powiązania:

https://bibliotekanauki.pl/articles/284115.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

nanotubes
gentamicin
drugs

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 93
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Multi-parametric SPR – in vitro characterization method for biopharmaceuticals and drug delivery systems

Autorzy:

Sadowski, J. W.
Granqvist, N.
Jokinen, A.

Powiązania:

https://bibliotekanauki.pl/articles/285101.pdf

Data publikacji:

2016

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

drugs
SPR
biopharmaceuticals

Źródło:

Engineering of Biomaterials; 2016, 19, 138; 120
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Selenium containing hydroxyapatite granules as drug carriers for risedronate

Autorzy:

Kolmas, J.
Pajor, K.
Pajchel, Ł.
Olędzka, E.
Sobczak, M.

Powiązania:

https://bibliotekanauki.pl/articles/285367.pdf

Data publikacji:

2016

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

hydroxyapatite
drugs
biomaterials

Źródło:

Engineering of Biomaterials; 2016, 19, 138; 70
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Problem legalizacji narkotyków miękkich w Polsce na tle regulacji prawnych przyjętych w Republice Czeskiej oraz w Królestwie Niderlandów
The issue of legalizing soft drugs in Poland against the legal regulations adopted in the Czech Republic and in the Netherlands

Autorzy:

Fiedukowicz, Marcin

Powiązania:

https://bibliotekanauki.pl/articles/964942.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

drugs
criminalization
decriminalization
drugs possession
soft drugs
legalization
prohibition
narkotyki
kryminalizacja
dekryminalizacja
posiadanie narkotyków
narkotyki miękkie
legalizacja
prohibicja

Opis:

Celem niniejszej publikacji jest przybliżenie unormowań prawnych odnoszących się do problematyki legalizacji oraz dostępności narkotyków miękkich w Polsce. W oparciu o regulacje prawa międzynarodowego, a także najważniejsze akty prawa wewnątrzwspólnotowego wskazuje się na zasadnicze przyczyny, dla których depenalizacja zachowań polegających na posiadaniu bądź też wytwarzaniu tzw. soft drugs nie jest obecnie możliwa. Zestawienie przepisów karnych polskiej ustawy narkotykowej pozwala wytyczać pożądane kierunki zmian w polskim modelu prohibicyjnym. W tym kontekście autor prezentuje podstawowe założenia polityk antynarkotykowych przyjętych w Republice Czeskiej oraz w Królestwie Niderlandów, jako państw o mniej restrykcyjnym (radykalnym) podejściu do kwestii posiadania narkotyków. Podjęte rozważania pozwalają ostatecznie na sformułowanie odpowiedzi na pytanie: Czy zasadne jest zalegalizowanie chociażby tzw. „narkotyków miękkich”, czy też należy pozostawić obowiązujące unormowania prawne bez zmian, karząc zawsze i za każdy przejaw posiadania narkotyków i to bez względu na ich rodzaj?
The aim of this publication is to bring closer legal regulations referring to issues of legalization and availability of soft drugs in Poland. Basing on regulations of the international law as well as on the most important acts of the intra-Community law fundamental reasons are indicated for which depenalization of behaviours such as the possession or production of the so-called soft drugs is not at present possible. Comparing regulations of penalties of the Polish drug act allows setting necessary guidelines for changes to the Polish prohibition model. In this context the author is presenting fundamental assumptions of the anti-drug policies adopted in the Netherlands and Czech Republic as the states with a less restrictive (radical) approach to the issue of drug possession. The considerations undertaken allow finally formulating an answer to a question: Is it reasonable to legalize at least the so-called ‘soft drugs’ or should the binding legal regulations be maintained without changes, punishing always and for every manifestation of drug possession and irrespectively of a type of drugs?

Źródło:

Acta Universitatis Lodziensis. Folia Iuridica; 2016, 76
0208-6069
2450-2782

Pojawia się w:

Acta Universitatis Lodziensis. Folia Iuridica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

Correlation between relative rates of hospital treatment or death due to ischaemic heart disease (IHD) and of IHD-related medication among socio-occupational and economic activities groups in Denmark, 1996–2005

Autorzy:

Hannerz, Harald
Dalhoff, Kim
Burr, Hermann
Latza, Ute

Powiązania:

https://bibliotekanauki.pl/articles/2178871.pdf

Data publikacji:

2014-08-06

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

pccupational epidemiology
heart therapeutic drugs
anti-hypertensive drugs
lipid modifying agents

Opis:

Objective: The aim of the present work was to establish whether or not prescribed medication is a usable risk indicator for work‑related ischaemic heart disease (IHD), in Denmark. Material and Methods: Weighted Spearman rank correlation coefficients (rho) were used to evaluate the agreement between Standardised Hazard Ratios (SHR) for hospital treatment or death due to IHD and SHR for purchase of prescriptions for medicine that may prevent IHD from (re)occurring, among socio-occupational and economic activities groups in Denmark. The SHR were based on a 10-year prospective follow-up of 2 million people in Danish national registers 1996–2005. Results: We found approximately 7 times more cases of medicine usage (N = 411 651) than we did for hospital treatment or death (N = 55 684). The correlations between the 2 types of SHR were strong (rho = 0.94 for the socio-occupational groups; rho = 0.74 for the economic activities groups). We observed, however, one markedly contradictive result; the industrial group entitled ‘general practitioner, dentists etc.’ was associated both with significantly high rates of medicine usage (SHR = 1.15, 95% CI: 1.12–1.19) and significantly low rates of hospital treatment or death due to IHD (SHR = 0.80, 95% CI: 0.71–0.91). Conclusion: Apart from a few caveats, the strong correlations obtained in the present study signify that purchase of a prescription for IHD-related medication is a usable risk indicator for IHD in the working population of Denmark. The usage of medicine data in addition to or instead of the use of death or hospital data in epidemiological studies on work-related IHD risk will bring about a tremendous increase in statistical power.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2014, 27, 4; 536-546
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Chitosan based drug delivery systems

Autorzy:

Piegat, A
Goszczyńska, A.
Niemczyk, A.

Powiązania:

https://bibliotekanauki.pl/articles/285591.pdf

Data publikacji:

2016

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

drugs
polymeric materials
chitosan

Opis:

One of the research area in which polymeric materials are intensively explored, deals with the controlled drug delivery systems (DDSs), allowing for drugs distribution directly to the desired site of biological activity. The morphology of polymeric colloidal drug carriers can be described as a construction of a core-shell type. Depending on the chemical or physical bonds providing stability of those systems and the type of interactions between the drug and the polymer, among polymeric DDSs the following morphological structures can be distinguished: micelles, dendrimers, liposomes, niosomes, polymerosomes and micro- and nanocapsules [1]. The main advantages of those systems are the preparation of particles with desired size (diameter from nano to micrometers) during their synthesis / formation and high specific surface area, which can be modified by the appropriate chemical composition of the surface improving the efficiency of a drug delivery. Chitosan is biopolymer derived from chitin, that is characterised by biodegradability, biocompatibility, mucoadhesion and antimicrobial activity [2,3]. Taking into account the overall advantages of this polymer and the possibility of modification due to the accessible functional groups i.e. hydroxyl and amine, chemically modified chitosan is one of the most promising biomaterials for DDS. In order to obtain micelle structures by selfassemby in aqueous environment several hydrophobically modified chitosan derivatives, such as – stearic acid-modified chitosan [4], palmitic anhydridemodified chitosan [5], linolenic acid-modified chitosan [6], have been synthesized. The micelles prepared by these derivatives in the aqueous medium contain internal hydrophobic moieties as drug reservoir and external hydrophilic chitosan chains as surrounding shell. The above mentioned micellar systems allow encapsulation of hydrophobic antitumor drugs e.g. doxorubicin or paclitaxel due to the compatibility between the hydrophobic core and hydrophobic drug affecting the drug loading and regulate drug release. Another important group of chitosan based micro- and nanoparticles are those dedicated for gastric infection treatment. The use of chitosan in this specific application is mainly related with the mucoadhesive properties of chitosan resulted from the electrostatic interactions between its positively charged free amine groups and the negatively charged gastric mucins at the acidic stomach pH. Several problems such as high solubility of chitosan under stomach acidic conditions, low retention time and difficulty in crossing the mucus barrier have been observed in those systems [7]. Therefore various crosslinking methods e.g. with glutaraldehyde [8], genipin [9] or sodium triphosphate pentabasic (TPP) solution [10] were investigated in order to minimize these problems. The nanotechnological production of the polymeric drug carriers, as well as the disadvantages of already developed chitosan based drug delivery systems induce the NANOENCAP project concept on the development and characterization of new dendrimeric micelles polymeric systems, with rigidly defined chemical structure, allowing the encapsulation of several drugs and their controlled release, and thus forming the so-called multidrug therapy systems. To provide the biocompatibility of new polymeric materials the monomer / reactant with proven biocompatibility or naturally occurring in the human body are chosen. According to the assumptions of the project the amphiphilic character of the proposed multi-functional polymeric drug delivery systems is going to enable the encapsulation of at least two drugs, matching latest trends in the research on DDS models in multi-therapy. As an exemplary multi-drug therapy in this project, the combine therapy of peptic ulcer disease was chosen. In this work we would like to present the short review of chitosan based drug delivery systems and the concept of the project as well as preliminary studies on new chitosan derivatives and the possibility of synthesis new micellar structures.

Źródło:

Engineering of Biomaterials; 2016, 19, 138; 27
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

Carbon nanopowders in technology drug form

Autorzy:

Skibska, B.
Bodek, K. H.

Powiązania:

https://bibliotekanauki.pl/articles/285643.pdf

Data publikacji:

2016

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

carbon nanopowders
drugs
biotechnology

Źródło:

Engineering of Biomaterials; 2016, 19, 138; 81
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 12.

Tytuł:

Sonochemical synthesis of drug molecules nanoparticles: towards controlled drug release

Autorzy:

Chytrosz, P.
Golda-Cepa, M.
Kotarba, A.

Powiązania:

https://bibliotekanauki.pl/articles/286014.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

nanoparticles
drugs
sonochemical synthesis

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 69
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 13.

Tytuł:

Charakterystyka wpływu narkotyków na ośrodkowy układ nerwowy

Autorzy:

Panas, Krystyna Teresa

Powiązania:

https://bibliotekanauki.pl/articles/2140999.pdf

Data publikacji:

2011

Wydawca:

Instytut Studiów Międzynarodowych i Edukacji Humanum

Tematy:

drugs addiction
nervous system

Opis:

Article covers the issues: Substances opóźniająco the central nervous system Substances stimulating the central nervous system Substances that cause disturbances in the central nervous system Escape from the daily concerns and environmental impact

Źródło:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne; 2011, 2(7); 253-263
1898-8431

Pojawia się w:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Opinia prawna stanowiąca uzupełnienie opinii na temat obowiązku wprowadzenia przez Polskę do sprzedaży aptecznej bez recepty produktu leczniczego ellaOne
Legal opinion complementing the opinion on Poland’s obligation to allow sale in pharmacies of a medicinal product ellaOne without prescription

Autorzy:

Kondrat, Mariusz

Powiązania:

https://bibliotekanauki.pl/articles/2223418.pdf

Data publikacji:

2015

Wydawca:

Kancelaria Sejmu. Biuro Analiz Sejmowych

Tematy:

contraception
drugs
European Union

Opis:

The author provides an analysis of Poland’s obligations as a Member State of the European Union, relating to the implementation of Community law in so far as it concerns Ellaone contraceptive. He points out that Regulation 726/2004 does not regulate issues related to the marketing of medicinal products in a comprehensive manner. Directive 2001/83/EC of the European Parliament and of the Council, according to its Article 4 para. 4, does not affect the application of national legislation prohibiting or restricting the sale or use of medicinal products as contraceptives or abortifacients. In Poland, there is no legislation expressly establishing a ban or restrictions on marketing or application of this particular type of agents, and any possible national legislation introduced to implement the restrictions permitted under the Directive should not only aim at eliminating the effect of the decision of the European Commission amending marketing authorisation issued by a decision (2009) 4049 for “ellaOne – ulipristal acetate”, a medicinal product for human use, but should relate to this category of products.

Źródło:

Zeszyty Prawnicze BAS; 2015, 1(45); 100-106
1896-9852
2082-064X

Pojawia się w:

Zeszyty Prawnicze BAS

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

Liposomal drug delivery, a novel approach: PLARosomes.

Autorzy:

Kozubek, Arkadiusz
Gubernator, Jerzy
Przeworska, Ewa
Stasiuk, Maria

Powiązania:

https://bibliotekanauki.pl/articles/1044303.pdf

Data publikacji:

2000

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

drugs
liposomes
vesicles
amphiphiles

Opis:

Almost from the time of their rediscovery in the 60's and the demonstration of their entrapment potential, liposomal vesicles have drawn attention of researchers as potential carriers of various bioactive molecules that could be used for therapeutic applications in humans and animals. Several commercial liposome-based drugs have already been discovered, registered and introduced with great success on the pharmaceutical market. However, further studies, focusing on the elaboration of more efficient and stable amphiphile-based vesicular (or non-viral) drug carriers are still under investigation. In this review we present the achievements of our group in this field. We have discovered that natural amphiphilic dihydroxyphenols and their semisynthetic derivatives are promising additives to liposomal lipid compositions. The presence of these compounds in lipid composition enhances liposomal drug encapsulation, reduces the amount of the lipid carrier necessary for efficient entrapment of anthracycline drugs by a factor of two, stabilizes liposomal formulation of the drug (both in suspension and in a lyophilized powder), does not influence liposomal fate in the blood circulation system and benefits from other biological activities of their resorcinolic lipid modifiers.

Źródło:

Acta Biochimica Polonica; 2000, 47, 3; 639-649
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Alginate/chitosan hybrid materials loaded with ciprofloxacin

Autorzy:

Kyzioł, A.
Mazgała, A.
Michna, J.
Regiel-Futyra, A.
Moreno, I.
Sebastian, V.
Irusta, S.

Powiązania:

https://bibliotekanauki.pl/articles/284972.pdf

Data publikacji:

2016

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

drugs
hybrid materials
biopolymers

Źródło:

Engineering of Biomaterials; 2016, 19, 138; 106
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 17.

Tytuł:

Porous hybrid materials as potential drug delivery systems

Autorzy:

Pajchel, Ł.
Szulkowska, A.
Kolmas, J.

Powiązania:

https://bibliotekanauki.pl/articles/283765.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

hybrid materials
drugs
composites

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 43
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 18.

Tytuł:

A comprehensive review on Primary gallbladder tuberculosis

Autorzy:

Gupta, Ashish
Gupta, Amit
Anjum, Rohik
Agrawal, Saumya
Mallik, Dhiraj

Powiązania:

https://bibliotekanauki.pl/articles/1392736.pdf

Data publikacji:

2018

Wydawca:

Index Copernicus International

Tematy:

gallbladder
Tuberculosis
Antitubercular drugs

Opis:

Tuberculosis (TB) is an infectious disease that can affect any organ system of the body. Abdominal TB can be gastrointestinal, lymph nodal, visceral or peritoneal. The gallbladder (GB) is rarely involved in abdominal TB as a primary organ. Extensive research literature on gallbladder TB is limited to case reports. There has been no review on this rare abdominal pathology. GB tuberculosis is a difficult diagnosis preoperatively. It is a rare differential among the more common gallbladder pathologies such as cholelithiasis, or a gallbladder malignancy. Typical histopathology of the resected specimen helps to establish this rare diagnosis. Subjecting every specimen to histopathological examination followed by medical treatment offers the chance of cure. Through this review, the authors attempt to provide an insight into this disease entity.

Źródło:

Polish Journal of Surgery; 2018, 90, 2; 10-12
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

Opinia na temat obowiązku wprowadzenia przez Polskę do sprzedaży aptecznej bez recepty produktu leczniczego ellaOne
Opinion on Poland’s obligation to allow sale in pharmacies of a medicinal product ellaOne without prescription

Autorzy:

Olejniczak, Dorota
Kuszel, Konrad

Powiązania:

https://bibliotekanauki.pl/articles/2223417.pdf

Data publikacji:

2015

Wydawca:

Kancelaria Sejmu. Biuro Analiz Sejmowych

Tematy:

contraception
drugs
European Union

Opis:

The opinion deals with the effects of the European Commission Implementing Decision whereby ellaOne is commercially available in all Member States without a prescription. The analysis leads to the conclusion that under the existing law, Poland is obliged to implement the decision of the Executive Committee and the medicinal product ellaOne should be available over-the-counter. Nevertheless, Polish legislature may decide to exclude or restrict the sale or use of medicinal products as contraceptives or abortifacients. Therefore, it is permissible to adopt a regulation to prohibit the sale of ellaOne or adopt provisions specifying that it will be available in Poland only on prescription.

Źródło:

Zeszyty Prawnicze BAS; 2015, 1(45); 93-99
1896-9852
2082-064X

Pojawia się w:

Zeszyty Prawnicze BAS

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 20.

Tytuł:

THE COMPREHENSIBILITY OF LEAFLETS ATTACHED TO OTC ANALGESICS – PILOT SURVEY OF OPINIONS IN POLAND

Autorzy:

Bułaś, Lucyna
Hansel, Justyna
Wajda, Anna
Dolińska, Barbara
Drozd, Mariola

Powiązania:

https://bibliotekanauki.pl/articles/895603.pdf

Data publikacji:

2019-12-29

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

OTC analgesics
leaflet attached to the drugs
source of information about OTC drugs

Opis:

The aim of the study was to present the opinions on the leaflets attached to the packages of Over-the-counter (OTC) analgesics, taking into account the place of purchase and the usefulness of the information contained in the leaflet. The survey was conducted in Poland at the turn of February/March 2016 and June/July 2017. The authors constructed an original questionnaire consisting of 24 questions, both open and closed type. The survey was addressed to adults. In total 303 respondents were surveyed. Student t-test and Pearson’s chi-squared test were applied to determine differences between statistics, p < 0.05 was assumed as statistically significant. The respondents indicated a pharmacy as the main place of purchasing OTC analgesics. Most of the respondents declared that they read the leaflet attached to the package, and the font size used is large enough and legible. However, if it is difficult to read the information contained in it, and the majority of patients do not turn to the doctor or pharmacist for advice. The obtained results confirm that patients purchase and use drugs with increasing awareness. The study found that patients do not always understand drug information leaflets, and they do not always turn to professionals for counseling. The information contained in leaflets should be presented in a way that is clear, concise, and easily understandable to patients. It appears that the implementation of pharmaceutical care would greatly improve the safety of pharmacotherapy, including OTC non-steroidal anti-inflammatory drugs (NSAIDs).

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1099-1106
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 21.

Tytuł:

Utilisation of peptides against microbial infections – a review

Autorzy:

Mirski, T.
Niemcewicz, M.
Bartoszcze, M.
Gryko, R.
Michalski, A.

Powiązania:

https://bibliotekanauki.pl/articles/2081601.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

antimicrobial peptides
infections
drugs
therapy

Opis:

The emergence of resistance in microorganisms on a global scale has made it necessary to search for new antimicrobial factors. Antimicrobial peptides (AMPs) seem to meet these expectations. AMPs are produced by bacteria, viruses, plants, and animals, and may be considered as a new class of drugs intended for the prophylaxis and treatment of both systemic and topical infections. The aim of this study is to review the results of studies on the use of peptides to combat infections in vivo. Antimicrobial peptides may be applied topically and systemically. Among the peptides used topically, a very important area for their application is ophthalmology. AMPs in ophthalmology may be used mainly for the protection of contact lenses from ocular pathogens. Many AMPs are in clinical trials for application in the therapy of local infections. There may be mentioned such preparations as: pexiganan (magainin analogue), MX-226 (based on indolicidin), NEUPREX (isolated from human BPI (bactericidal/permeability-increasing) protein), IB-367 (variant of porcine protegrin), P113 (based on histatin), daptomycin, polymyxins, as well as peptidomimetics. In the combat against systemic infections are used such peptides as: P113D (modified P113 peptide containing D-amino acids), colistin, peptoids, and peptides containing non-typical amino acids or non-peptide elements. AMPs are also used as antiprotozoal, antifungal, antitoxic and immunostimulatory agents. The limitations in the use of peptides in the treatment of infections, such as susceptibility to proteolysis, and resistance of microorganisms to the peptides, are also discussed. AMPs are a promising strategy in the fight against microbial infections.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 205-210
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Self-Declaration of Religiousness and This Variable’s Connections with Indications of Psychoactive Substance Use: Data from Empirical Studies (N=2273)

Autorzy:

Jedynak, Witold
Motyka, Marek A.

Powiązania:

https://bibliotekanauki.pl/articles/2036275.pdf

Data publikacji:

2018

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL

Tematy:

religiousness
morality
youth
drugs
addiction

Opis:

A steady increase in the use of intoxicants is being confirmed by empirical studies. One of the factors conducive to drug initiation is the rejection of moral norms associated with religious beliefs. The article presents the relations established between the youth’s declared religiousness and their statements on psychoactive drugs and using them. The data were collected through questionnaire surveys carried out on a randomly selected sample of high school students from the Podkarpackie region (n = 2273). The research results suggest that the process of secularisation and relativisation observed among the youth, particularly in the sphere of morality, may weaken critical attitudes towards psychoactive substances, both those legally allowed and those prohibited by law. Moreover, the links between the declared religiousness and such variables as: time spent on the Internet, acquaintances who are drug users, being raised by a single parent or both parents as well as the frequency of conversations between respondents and their parents were established. The connections between these variables are statistically significant, so it can be concluded that these distinguished variables influence the diversity in religiousness stated by participants and consequently the liberalisation of the youth’s attitudes towards drugs.

Źródło:

Roczniki Teologiczne; 2018, 65, 10 English Online Version; 141-163
2353-7272

Pojawia się w:

Roczniki Teologiczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

Comparative analysis of porous polymeric membranes as drug carriers

Autorzy:

Stodolak-Zych, E.
Mikołajczyk, M.
Rapacz-Kmita, A.

Powiązania:

https://bibliotekanauki.pl/articles/285554.pdf

Data publikacji:

2017

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

polymeric membranes
drugs carriers
polymers

Źródło:

Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 53
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 24.

Tytuł:

Drug - eluting bioresorbable vascular stents manufactured by microinjection moulding

Autorzy:

Dobrzyński, P.
Sobota, M.
Włodarczyk, J.
Stoiko, M.
Pastusiak, M.
Kasperczyk, J.
Milewski, K.
Krauze, A.

Powiązania:

https://bibliotekanauki.pl/articles/284470.pdf

Data publikacji:

2018

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

vascular stents
bioresorbable stent
drugs

Źródło:

Engineering of Biomaterials; 2018, 21, 148; 33
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

Boosters – a Phenomenon and Threats

Autorzy:

Jędrzejko, Mariusz
Netczuk-Gwoździewicz, Marzena

Powiązania:

https://bibliotekanauki.pl/articles/1861554.pdf

Data publikacji:

2016

Wydawca:

Wyższa Szkoła Bezpieczeństwa Publicznego i Indywidualnego Apeiron w Krakowie

Tematy:

boosters
drugs
psychoactive substances
poisoning

Opis:

the article is an analysis of the issue of drugs consumption, in the historical context, and concentrates on the synthetic drugs production that lasts for the last decades. authors mainly focus on the most present topic – the boosters: their impact on health (intoxication), distribution and production. they consider measures taken by authorities to fight this phenomenon, as well as show its partial efficiency due to changes in boosters production (flexible changes of consistence) and distribution (foreign platforms use).

Źródło:

Security Dimensions; 2016, 17(17); 99-113
2353-7000

Pojawia się w:

Security Dimensions

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 26.

Tytuł:

Metody przemycania narkotyków oraz sposoby ich rozpoznawania
Drug smuggling techniques and methods of detection

Autorzy:

Lewkowicz, A.

Powiązania:

https://bibliotekanauki.pl/articles/348215.pdf

Data publikacji:

2011

Wydawca:

Akademia Wojsk Lądowych imienia generała Tadeusza Kościuszki

Tematy:

narkotyki
przemytnictwo
transport
drugs
smuggling

Opis:

Narkotyki to współcześnie jedno z najpoważniejszych zagrożeń bezpieczeństwa wewnętrznego państw jak i światowym problemem zdrowotnym w walce od uniezależnienia od narkotyków oraz przestępczości narkotykowej. Polska ze względu na centralne położenie w Europie stała się krajem tranzytowym dla narkotyków przerzucanych z Bliskiego i Dalekiego Wschodu. Współczesne dochody z przemytu narkotyków przeznaczane są na pomnażanie zasobów finansowych organizacji przestępczych. Pieniądze te stanowią źródło do dalszego jeszcze większego pomnażania ich do innych zabronionych celów niezgodnych z prawem.
Organised crime in the form of drug smuggling and trafficking poses a serious threat to public safety. Drug addiction also constitutes a global health hazard.

Źródło:

Zeszyty Naukowe / Wyższa Szkoła Oficerska Wojsk Lądowych im. gen. T. Kościuszki; 2011, 4; 99-108
1731-8157

Pojawia się w:

Zeszyty Naukowe / Wyższa Szkoła Oficerska Wojsk Lądowych im. gen. T. Kościuszki

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 27.

Tytuł:

Counterfeited drugs – the economic impact

Autorzy:

Sichel, Ricardo Luiz

Powiązania:

https://bibliotekanauki.pl/articles/581450.pdf

Data publikacji:

2017

Wydawca:

Wydawnictwo Uniwersytetu Ekonomicznego we Wrocławiu

Tematy:

counterfeited drugs
medicaments
economic impact

Opis:

The problem of counterfeited medicines causes expenditures for the health institutions and public authorities, especially when public health service is concerned. It also causes an expressive loss for the public budget, because of less taxes paid or jobs lost, which has as consequence the payment of welfare money. Moreover, it is also a huge net of illegal activities that finance other forms of illicit activities, such as terrorism, drugs, etc. The paper analyses the economic impact of the trade of illegal products from the perspective of brands which are recognized by consumers and in the context of social interest and problems of public health that are related to the use of inadequate products or medicaments which contained substances that damage the health. It is concluded that the administrative measures that have to be undertaken cannot be limited to the national authorities but should be the result of international cooperation.

Źródło:

Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu; 2017, 474; 203-212
1899-3192

Pojawia się w:

Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 28.

Tytuł:

Uwarunkowania liberalizacji stanowisk wobec narkotyków oraz ich zażywania zidentyfikowane w środowisku szkolnym – dane z badań
Reasons for the Liberalization of Attitudes Towards Drugs and their Use Identified in the School Environment – Research Data

Autorzy:

Motyka, Marek A.

Powiązania:

https://bibliotekanauki.pl/articles/916450.pdf

Data publikacji:

2019-12-15

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

youth
school environment
alcohol
drugs

Opis:

Over the past few decades, researchers of drug addiction have drawn attention to the unprecedenteddynamics in the positions on drugs and a growing number of people who admit to the use of suchsubstances for hedonistic and recreational purposes. An intensification of drug addiction led to theidentification of a large number of drug-related problems which occur on individual, social and globallevels. The last decade has abounded in seemingly uncontrollable, numerous events linked mainly to the spread of “legal highs”. These events included: legal trade in those products in Poland, two waves of numerous deaths associated with their use, the extremely unscrupulous distribution of “legal highs”through websites, and particularly the liberalisation of attitudes towards those new designer drugs. The considerable importance in creating positions in favour of drug use should also be attributed to the popularity of marijuana, increasingly gaining a status of a recreational drug. This paper discusses the current reasons why the youth begin to use drugs as identified in the school environment. The research focused on obtaining reliable data allowing to diagnose the phenomenon of drug use by the young people in Podkarpacie Province and to determine factors contributing to drug initiation among this segment of population. In the quantitative research, the empirical data were collected through a specially designed questionnaire from a random sample of young people from 27 secondary schools in Podkarpacie Province (n=2237). Within the sample, 712 students (31%) admitted to using drugs. The most important educational factors for promoting psychoactive substances are low involvement in education and frequent school absences. Drugs are more commonly used by older students. The research material presented in this article can be successfully used by practitioners in the field, including sociologists, educators and psychologists, and by institutions active in social prevention. It can also form the starting point for further explorations of this important social phenomenon.

Źródło:

Studia Edukacyjne; 2019, 55; 223-244
1233-6688

Pojawia się w:

Studia Edukacyjne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 29.

Tytuł:

Drug use, smoking, alcohol abuse and assertiveness of medical students from Poland and Belarus

Autorzy:

Kułak-Bejda, A.
Waszkiewicz, N.
Shpakau, A.
Bejda, G.
Dróżdż-Kubicka, E.

Powiązania:

https://bibliotekanauki.pl/articles/1918791.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Smoking
drugs
alcohol
medical students

Opis:

Introduction: Human health is largely determined by factors such as human behavior and style of life. Purpose: To evaluate selected patterns of behavior of medical students, such as smoking, alcohol abuse, drug use, and their assertiveness. Materials and methods: The study included 338 students from Bialystok, Poland, and 339 from Grodno, Belarus. The original questionnaire, Fasterström's Nicotine Addiction Test, Michigan Alcoholism Screening Test, Drug Use Problem Test, and Assertiveness Test according to Grębski were all used. Results: In both groups, the level of cigarette dependence was low, with 10% of the students from Poland and 15% from Belarus being habitual cigarette smokers. No significant differences were found in the frequency of alcohol consumption between Polish (57%) and Belarusian (52%) students. Of the respondents, 3.3% from Poland and 1.5% from Belarus met the criteria of alcohol dependence according to the MAST test. There were no statistically significant differences in the frequency of drug use between the Polish (1.5%) and Belarusian (1.8%) students. The average level of assertiveness was 16.2 for Polish students and 15.4 for Belarusian students, which was a significant difference. Conclusions: These results indicate similar percentages of Polish and Belarusian students smoke cigarettes, drink alcohol, and use drugs. In addition, Polish students were more assertive than Belarusian students.

Źródło:

Progress in Health Sciences; 2018, 8(2); 62-69
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Syndrome of inappropriate secretion of ADH in the course of chemotherapy for anaplastic large T-cell lymphoma of the lung

Autorzy:

Kade, Grzegorz
Michalak, Maciej
Straszyńska, Aleksandra
Moczulski, Dariusz
Hałka, Janusz
Spaleniak, Sebastian

Powiązania:

https://bibliotekanauki.pl/articles/2159011.pdf

Data publikacji:

2022-06-30

Wydawca:

Medical Education

Tematy:

SIADH
hyponatremia
lymphoma
antineoplastic drugs

Opis:

The present study reports the case of a 40-year-old patient who presented SIADH syndrome due to anaplastic large T-cell lymphoma and antineoplastic drugs.

Źródło:

OncoReview; 2022, 12, 2; 50-53
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

A comprehensive review of primary gall bladder tuberculosis

Autorzy:

Gupta, Ashish
Gupta, Amit
Anjum, Rohik
Agrawal, Saumya
Mallik, Dhiraj

Powiązania:

https://bibliotekanauki.pl/articles/1392422.pdf

Data publikacji:

2018

Wydawca:

Index Copernicus International

Tematy:

Gall bladder
Tuberculosis
Antitubercular drugs

Opis:

Tuberculosis (TB) is an infectious disease that can involve any organ system of the body. Abdominal TB can be gastrointestinal, lymph-nodal, visceral or peritoneal. Gall bladder (GB) is rarely involved as a primary organ in abdominal TB. On extensive research, the literature on gall bladder TB is limited to case reports. There has been no review on this rare abdominal pathology. The GB tuberculosis is difficult to diagnose preoperatively. It is a rare differential among the more common gall bladder pathologies like cholelithiasis, or a gall bladder malignancy. Standard histopathology of a resected specimen helps in this rare diagnosis. Subjecting every specimen to histopathological examination followed by medical treatment offers a chance to cure. Through this review the authors have tried to provide an insight into this entity.

Źródło:

Polish Journal of Surgery; 2018, 90, 4; 52-54
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

Zaburzenia wydzielania prolaktyny w trakcie stosowania leków psychotropowych innych niż leki przeciwpsychotyczne
Disturbances of prolactin secreting during treatment with psychotropic drugs other than antipsychotics

Autorzy:

Barszcz, Zbigniew
Rabe-Jabłońska, Jolanta

Powiązania:

https://bibliotekanauki.pl/articles/945566.pdf

Data publikacji:

2007

Wydawca:

Medical Communications

Tematy:

antidepressant drugs
benzodiazepins
benzodiazepiny
hiperprolaktynemia
hyperprolactinaemia
leki normotymiczne
leki przeciwdepresyjne
normothymic drugs
prolactin
prolaktyna

Opis:

The aim of this paper is to present current views on disorders of pituitary prolactin secretion during treatment with psychotropic drugs other than antipsychotic preparations. This issue was hitherto only rarely addressed to in the literature. While association between prolactin secretion and use of antipsychotic drugs was the subject of several methodologically correct studies, our knowledge on correlations of prolactin secretion disorders and administration of antidepressants, normothymics or sedatives stems mainly from studies encompassing small groups of patients or from anecdotal case reports. Modest number of publications concerning this issue may indicate that this problem either rarely occurs in everyday clinical practice or is inadequately diagnosed by clinicians and investigators. It appears, that psychotropic drugs other than antipsychotics rarely cause significant disorders of prolactin secretion and rarely lead to clinically significant hyperprolactinaemia. However, administration of many antidepressants (both tricyclic antidepressant and selective inhibitors of reuptake of serotonin) and some benzodiazepins, may induce increased pituitary prolactin secretion, which may result in clinical signs of hyperprolactinaemia. Few published studies indicate that normothymic drugs not only do not cause hyperprolactinaemia, but may even decrease its secretion.
Celem pracy jest przedstawienie wiedzy na temat zaburzeń wydzielania prolaktyny przez przysadkę w trakcie stosowania leków psychotropowych innych niż leki przeciwpsychotyczne. Kwestia ta była dotychczas bardzo rzadko opisywana w literaturze. O ile związki między wydzielaniem prolaktyny a stosowaniem leków przeciwpsychotycznych były przedmiotem licznych metodologicznie poprawnych badań, o tyle wiedza na temat związków między zaburzeniami wydzielania prolaktyny a stosowaniem leków przeciwdepresyjnych, normotymicznych czy uspokajających pochodzi przede wszystkim z badań prowadzonych na niewielkich grupach pacjentów lub z opisów pojedynczych przypadków. Niewielka liczba publikacji na ten temat może świadczyć o tym, że jest to problem rzadko spotykany w codziennej praktyce lekarskiej lub niedostatecznie rozpoznawany przez lekarzy i badaczy. Wydaje się, że leki psychotropowe inne niż leki przeciwpsychotyczne rzadko są przyczyną istotnych zaburzeń wydzielania prolaktyny, rzadko też powodują istotną klinicznie hiperprolaktynemię. Jednak w trakcie stosowania wielu leków przeciwdepresyjnych (zarówno z grupy trójpierścieniowych leków przeciwdepresyjnych, jak i z grupy selektywnych inhibitorów wychwytu zwrotnego serotoniny) oraz niektórych benzodiazepin może dochodzić do zwiększania wydzielania PRL przez przysadkę, co może manifestować się objawami klinicznymi hiperprolaktynemii. Z opublikowanych, choć nielicznych badań wynika, że leki normotymiczne nie powodują hiperprolaktynemii, przeciwnie – w trakcie ich stosowania może dochodzić do zmniejszania wydzielania prolaktyny.

Źródło:

Psychiatria i Psychologia Kliniczna; 2007, 7, 2; 103-107
1644-6313
2451-0645

Pojawia się w:

Psychiatria i Psychologia Kliniczna

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

Przeciwdziałanie sprzedaży dopalaczy – refleksje na tle ustaleń kontroli NIK
Preventing Sale of Designer Drugs – Reflections on the Basis of NIK’s Audit Findings

Autorzy:

Kujawiński, Radosław

Powiązania:

https://bibliotekanauki.pl/articles/416846.pdf

Data publikacji:

2017-08

Wydawca:

Najwyższa Izba Kontroli

Tematy:

designer drugs
counter sales
psychoactive substances
placing designer drugs on the market
drug addiction

Opis:

As a result of the development of designer drugs market and its negative consequences, the administration started fighting against their sale. The objective of the audit conducted by NIK was to examine how the responsible state bodies met their obligations in the area, and especially – whether their activities were effective. In relation to some of the issues identified as a result of the audit, we can talk about the expansion of the designer drugs market, since the conditions in which state bodies operate have been changing rapidly. This is especially related to administrative fines for placing designer drugs on the market, and the opportunity to subject activities related to the sale of these products to the law as it stands (de lege lata) criminal responsibility.

Źródło:

Kontrola Państwowa; 2017, 62, 4 (375); 62-76
0452-5027

Pojawia się w:

Kontrola Państwowa

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

Właściwości i oznaczanie substancji o działaniu psychoaktywnym
Properties and detection of ‘designer drugs’

Autorzy:

Jakubowska, I.
Choma, J.

Powiązania:

https://bibliotekanauki.pl/articles/210107.pdf

Data publikacji:

2013

Wydawca:

Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego

Tematy:

substancje o działaniu psychoaktywnym
właściwości substancji
metody analizy
designer drugs
drugs properties
analytical methods

Opis:

W artykule opisano substancje o działaniu psychoaktywnym działające na ośrodkowy układ nerwowy. Są to związki lub też mieszaniny związków syntetycznych (m.in. BZP - N benzylopiperazyna, mefedron, JWH-018 (naftalen-1-yl-(1-pentyloindol-3-yl)metanon), TFMPP - trifluorometylofenylo-piperazyna) oraz naturalne mieszanki zioł i roślin (np. szałwia wieszcza, kratom, muchomor czerwony, kava-kava itp.). Przedstawiono ich działanie i wpływ na ludzi zażywających je sporadycznie oraz regularnie. Ponadto opisano niebezpieczeństwa związane z zażywaniem tych środków. Przedstawiono przykładowe metody analizy. W tym celu wykorzystywana jest chromatografia cienkowarstwowa, jako metoda przygotowawcza połączona zwykle z ekstrakcją i stosowana zazwyczaj do oczyszczenia próbek. Przytoczono przykłady zastosowania chromatografii gazowej i cieczowej, jako głównych metod analizy substancji o działaniu psychoaktywnym.
The paper describes psychoactive substances acting on the central nervous system, commonly referred to as designer drugs. Designer drugs are compounds or mixtures of synthetic compounds (e.g. BZP - N-benzylpiperazine, mephedrone, JWH-018 (naphthalen-1-yl-(1-pentyloindol-3-yl)-methanone), TFMPP -trifluoromethylpiperazine) and natural blend of herbs and plants (e.g. sage poet, kratom, fly agaric, kava-kava, etc.). Their effects are presented, the impact on the people using them occasionally or regularly describes the hazards associated with the use of these funds. Analysis methods, based mainly on chromatographic methods, are also presented. Thin-layer chromatography, as a preparatory method, usually combined with extraction is used for samples purification. Application of gas chromatography and liquid chromatography as main methods of analysis is shown.

Źródło:

Biuletyn Wojskowej Akademii Technicznej; 2013, 62, 2; 123-143
1234-5865

Pojawia się w:

Biuletyn Wojskowej Akademii Technicznej

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

Aspekty etyczno-prawne legalizacji marihuany i innych narkotyków miękkich
Ethical and legal aspects of the legalization of marijuana and other soft drugs

Autorzy:

Kobyliński, Andrzej

Powiązania:

https://bibliotekanauki.pl/articles/470445.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie

Tematy:

narkotyki
marihuana
liście konopi
legalizacja narkotyków
godność człowieka
narkomania
narkotyki miękkie
drugs
marijuana
cannabis leaves
legalization of drugs
human dignity
drug addiction
soft drugs

Opis:

The main purpose of this article is to present the most important ethical and legal aspects of the legalization of marijuana and other soft drugs. The dispute over the legalization of access to the usage of drugs is an elevation to the point of moral revolution, which is currently engaged on a global scale. Over the past decade there has been strong shift in public opinion in many countries in favor of drug policy reform. Arguments about the prohibition of drugs and over drug policy reform are subjects of considerable controversy. The problem of legal access to drugs is a very complex interdisciplinary issue which requires a reliable diagnosis on the borderline of ethics, medicine, philosophy, law, sociology and political philosophy. The ethical evaluation of the usage of drug and distribution should always precede the adoption of specific measures of a legal nature.
Głównym celem artykułu jest prezentacja najważniejszych aspektów etycznych i prawnych legalizacji marihuany i innych narkotyków miękkich. Spór o legalizację dostępu do narkotyków jest przejawem rewolucji moralnej, która dokonuje się obecnie w wymiarze globalnym. W ostatnim dziesięcioleciu nastąpiło w wielu krajach silne przesunięcie nastrojów opinii publicznej na korzyść reformy polityki narkotykowej. Argumenty związane z zakazem dostępu do narkotyków i reformą polityki narkotykowej są obecnie przedmiotem poważnych kontrowersji. Problem prawnego dostępu do narkotyków stanowi bardzo złożoną kwestię interdyscyplinarną, która wymaga rzetelnej diagnozy z pogranicza etyki, medycyny, filozofii prawa, socjologii i filozofii politycznej. Etyczna ocena stosowania narkotyków i ich dystrybucji powinna zawsze poprzedzać przyjęcie określonych rozwiązań o charakterze prawnym.

Źródło:

Studia Ecologiae et Bioethicae; 2017, 15, 3; 69-81
1733-1218

Pojawia się w:

Studia Ecologiae et Bioethicae

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Chemiczne aspekty celowanej terapii przeciwnowotworowej II. Połączenia nośnik -lek
Chemical aspects of targeted anticancer therapy II . Bond of carrier to drug

Autorzy:

Werengowska, K. M.
Wiśniewski, M.
Terzyk, A.P.
Gurtowska, N.
Drewa, T. A.
Olkowska, J.

Powiązania:

https://bibliotekanauki.pl/articles/172570.pdf

Data publikacji:

2012

Wydawca:

Polskie Towarzystwo Chemiczne

Tematy:

nanonośniki leków
leki przeciwnowotworowe
wiązania kowalencyjne
adsorpcja
nanocarriers of drugs
anticancer drugs
covalent bonds
adsorption

Opis:

Traditional anticancer therapy is usually low effective. Popular and common drugs applied in anticancer therapy are characterized by low solubility and nonspecific biodistribution in an organism. The chemotherapy kills not only cancer but also healthy cells [4]. Building of modern drug delivery systems based on nanocarriers is a new method of anticancer treatment. The present study is directed towards nanomaterials (as carbon nanotubes, liposomes, polymeric micelles) as modern drug carriers. Thus, we characterized mechanisms of actions of traditional chemotherapeutics: paclitaxel, cisplatin and doxorubicin (Figs. 3–5) [1, 15, 21]. The purpose of this study is a description of the bioconjugation of drug-nanocarrier. Chemotherapeutics can be connected to external or internal surfaces of nanocarriers (Fig. 6) [6]. We described two main methods of drug delivery from internal space of nanocarriers: nanoextraction and nanocondensation (Fig. 7) [32]. The type of drug-carrier bonding can be covalent or noncovalent. We report recent advances in the field showing the formation of esters (Figs. 10–11) [28, 29, 53, 54], acethylhydrazone (Fig. 12) [55–61], amides [62–64], and disulfides groups [12, 65]. These reactions depend on functional groups in structures of drugs and require suitable modification of nanocarrier surfaces. In practice, the functionalization of nanocarrier surface is associated with the covering with polymers including PE G, HPMA, PG and PL GA [3]. Adsorption is the most popular process of bonding chemotherapeutic and nanomaterials (Fig. 13) [66]. Special attention is paid to electrostatic interaction between drugs: paclitaxel [74], cisplatin [59, 76, 77], doxorubicin [67–73] and nanocarriers: carbon nanotubes and/or polymeric micells. By application of modern anticancer therapy, drugs are preserved from lysosomal degradation and to fast reaction in biological environment. Finally, nanocarriers improve adsorption of drug and increase concentration of drug only in cancer tissues [6, 7].

Źródło:

Wiadomości Chemiczne; 2012, 66, 7-8; 637-670
0043-5104
2300-0295

Pojawia się w:

Wiadomości Chemiczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

Severe atopic dermatitis in children: therapeutic dilemmas
Atopowe zapalenie skóry o ciężkim przebiegu u dzieci: dylematy terapeutyczne

Autorzy:

Lis-Święty, Anna
Milewska-Wróbel, Dorota

Powiązania:

https://bibliotekanauki.pl/articles/1034806.pdf

Data publikacji:

2018

Wydawca:

Medical Communications

Tematy:

adherence
atopic dermatitis
immunosuppressive drugs
therapy

Opis:

Atopic dermatitis is the most common skin disorder diagnosed in early childhood. Some children do not experience a relief of symptoms as they get older, and severe atopic dermatitis may develop, with manifestations including widespread skin lesions and unremitting itching. The disease is both physically and emotionally disabling, and significantly compromises the patient’s quality of life. Indications to intensify therapy include resistance to topical treatment and multidrug resistance. However, in many cases non-adherence to the treatment regimen, including inadequate skin care techniques, contribute to the development of severe or refractory atopic dermatitis. Persistent eczematous lesions may be a result of exacerbating environmental factors, secondary infection, and hypersensitivity reactions to topical treatments or other allergens. Wet-wrap treatment with topical corticosteroids, narrow-band UVB phototherapy and systemic immunosuppressive drugs, such as cyclosporine A, methotrexate, mycophenolate mofetil and azathioprine, are recommended for the treatment of severe atopic dermatitis in children. However, there are no evidence-based guidelines for using these agents. Systemic corticosteroids should be avoided, but they can be used for a short period of time for the immediate relief of acute flares before introducing other therapies. Patients need a holistic approach including education and modern biopsychosocial techniques. Paediatric studies are currently under way to test the safety and tolerability of dupilumab which was approved by the US Food and Drug Administration in 2017 for the treatment of adults with moderate-to-severe atopic dermatitis.
Atopowe zapalenie skóry jest najczęstszym schorzeniem skóry rozpoznawanym we wczesnym dzieciństwie. U części dzieci objawy nie łagodnieją w miarę dorastania, lecz rozwija się atopowe zapalenie skóry o ciężkim przebiegu z uogólnionymi zmianami skórnymi, uporczywym świądem; choroba przyczynia się do cierpienia fizycznego i psychicznego, znacząco pogarszając jakość życia. Sygnałem do intensyfikacji terapii powinna być oporność na leczenie zewnętrzne i wielolekowość. Jednak w wielu przypadkach przyczyną ciężkiego i opornego na terapię atopowego zapalenia skóry jest niedostosowanie się do zaleceń terapeutycznych (non-adherence), w tym nieprawidłowa pielęgnacja skóry. Uporczywość zmian wypryskowych może być także skutkiem narażenia na środowiskowe czynniki drażniące, wtórnej infekcji, reakcji nadwrażliwości na leki zewnętrzne czy inne alergeny. W ciężkim atopowym zapaleniu skóry u dzieci zaleca się stosowanie mokrych opatrunków z kortykosteroidami miejscowymi, fototerapii światłem wąskopasmowym UVB, ogólnoustrojowych leków immunosupresyjnych, takich jak cyklosporyna A, metotreksat, mykofenolan mofetylu i azatiopryna. Brak jest wytycznych opartych na dowodach naukowych dotyczących leczenia tymi lekami. Należy unikać kortykosteroidów ogólnych, ale można zastosować krótkotrwałą terapię w celu szybkiego opanowania dużych zaostrzeń przed wdrożeniem innych form leczenia. Pacjenci wymagają podejścia holistycznego, obejmującego edukację i stosowanie nowoczesnych technik biopsychospołecznych. W populacji pediatrycznej obecnie prowadzone są badania kliniczne oceniające bezpieczeństwo i tolerancję dupilumabu, leku biologicznego zaaprobowanego w 2017 roku przez amerykańską Agencję ds. Żywności i Leków w leczeniu umiarkowanego i ciężkiego atopowego zapalenia skóry u dorosłych.

Źródło:

Pediatria i Medycyna Rodzinna; 2018, 14, 4; 376-380
1734-1531
2451-0742

Pojawia się w:

Pediatria i Medycyna Rodzinna

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 38.

Tytuł:

Narkotyczna odyseja z rozkładem społecznym w tle – „Ślepnąc od świateł” Jakuba Żulczyka
Narcotic Odyssey with Social Decay in the Background: “Ślepnąc od świateł” by Jakub Żulczyk

Autorzy:

Piechota, Dariusz

Powiązania:

https://bibliotekanauki.pl/articles/1520297.pdf

Data publikacji:

2018-12-20

Wydawca:

Uniwersytet w Białymstoku. Wydawnictwo Uniwersytetu w Białymstoku

Tematy:

novel
narcissistic society
drugs
consumerism
space

Opis:

The article interprets Ślepnąc od świateł [Blind from the Lights] as a postmodern environmental novel which shows the life of residents in a large metropolis, entangled in constant consumption. The author reads the story as a continuation of the nineteenth century novel about a social decay. He proves that the depicted society, delighted with consumer culture, wastes its opportunities for development. As a result of the breakdown of social ties and constant work, urbanites suffer from permanent loneliness. The disillusionment is alsointensified by the disappearance of spirituality.. The crisis of authority and social antagonisms further undermine the integrity and the sense of coherencein the self. But Żulczyk’s characters fail to reflect on life, which the author of the article sees as the sign of immaturity.

Źródło:

Białostockie Studia Literaturoznawcze; 2018, 13; 219-232
2082-9701
2720-0078

Pojawia się w:

Białostockie Studia Literaturoznawcze

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 39.

Tytuł:

HIV and other STI public prevention campaigns: Vain endeavours to break risky new trends in view of blending sex and drugs

Autorzy:

Dennin, R.H.

Powiązania:

https://bibliotekanauki.pl/articles/1917733.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

HIV
prevention concepts
barriers
psychotropic drugs

Opis:

Although at the global level the incidence of HIV has declined there are contrary trends gaining momentum. Unimpressed by public prevention campaigns certain groups belonging to the ‘at-risk' population are engaging in risky sexual behaviour and concomitant misuse of illicit drugs thereby potentiating the odds of spreading HIV and other sexually transmitted infections (STIs). The blending of drug misuse with substantial risky sexual behaviour increases those risks and creates an almost inseparable complexity. Group-sex settings of this kind are partly organised via national and international social networks. Those people engaged in this modern trend mostly present with various health impairments thereafter, such as unconsciousness or confusion, often rendering them unable to adhere to combined antiretroviral therapy (cART) if they are HIV-infected. These people staunchly refuse to cooperate with prevention messages. Thereby public prevention efforts to curb the spread of HIV are largely wasted. But it is not just the individual’s issue; if developments of this kind are not contained serious challenges with HIV and other STIs might arise for these communities

Źródło:

Progress in Health Sciences; 2016, 6(1); 158-164
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 40.

Tytuł:

Illicit drug use and Romanian adolescents. Parental protective factors
Nielegalne zażywanie narkotyków a młodociani Rumuni. Rodzicielskie czynniki ochronne

Autorzy:

Bărbat, Aurora Carmen

Powiązania:

https://bibliotekanauki.pl/articles/475387.pdf

Data publikacji:

2012

Wydawca:

Uniwersytet Opolski. Redakcja Wydawnictw Wydziału Teologicznego

Tematy:

adolescence
illicit drugs
protective factors
parents

Opis:

The present study used the „CORT 2004 Questionnaire Regarding Risk Behavior for Health in Young People” for an epidemiological survey on 2908 high school students of the urban area of Timis County, western Romania. The aim of this study is to analyze the magnitude of the illicit drug use of Romanian adolescents and to delineate the parental protective factors inside the family.

Źródło:

Family Forum; 2012, 2; 107-117
2084-1698

Pojawia się w:

Family Forum

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Dextromethorphan recreational use and poisoning – the social and psychological background

Autorzy:

Koziarska-Rościszewska, Małgorzata
Piątek, Aleksandra
Kobza-Sindlewska, Katarzyna
Krakowiak, Michał
Winnicka, Renata
Krakowiak, Anna

Powiązania:

https://bibliotekanauki.pl/articles/552647.pdf

Data publikacji:

2018

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

substance addiction
dextromethorphan
poisoning
recreational drugs.

Źródło:

Family Medicine & Primary Care Review; 2018, 2; 139-143
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 42.

Tytuł:

Rozkosze immunizacji – biopolityka substancji psychoaktywnych

Autorzy:

Gulik, Michał

Powiązania:

https://bibliotekanauki.pl/articles/636819.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego

Tematy:

designer drugs, agency, materialism, biopolitics, posthumanism

Opis:

The article is an attempt to analyse the emergent practices around designer drugs in the perspective of Roberto Esposito’s biopolitics. New psychoactive substances are understood as technologies that – at the same time – support and subvert the logics of immunization, reestablishing the relationship between subject and object. The author juxtaposes post-Foucaultian and post-Lacanian theories of drug addiction as two possible ways of understanding the realtion between the drug and its user, both failing to account for the agency of the object itself. The excessive nature of designer drugs makes them immune to legal procedures, but also at the same time, reveals the shortcommings of critical discourse analysis. The author emphasizes the need to incorporate the accomplishments of new materialism and object-oriented philosophy into the realm of cultural studies analysis. Following Dunne’s design theory, he describes new ways of knowledge production in designer drugs communities, and examines them in the context of biohacking and bio-DIY communities. The article is aimed at establishing the biopolitical theory of drugs, that provides a better understanding for contemporary media practices around designer drugs.

Źródło:

Przegląd Kulturoznawczy; 2014, 2(20)
1895-975X
2084-3860

Pojawia się w:

Przegląd Kulturoznawczy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 43.

Tytuł:

Preparation of scutellarin loaded TPGS polymeric micelles and evaluation of its pharmacokinetics and pharmacodynamics effects in rats

Autorzy:

Zou, Liu
Xiong, Shujuan
Deng, Xiangping
Liu, Juan
Xiong, Runde
Wang, Zhe
Cao, Xuan
Chen, Yanming
Guo, Yu
Tang, Guotao

Powiązania:

https://bibliotekanauki.pl/articles/895637.pdf

Data publikacji:

2018-12-31

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

scutellarin
TPGS
polymeric micelles
antithrombotic drugs

Opis:

To improve the clinical effect of scutellarin by extending the action time in vivo, scutellarin loaded polymeric micelles were developed by D-alpha tocopherol polyethylene glycol 1000 succinate (Scu/TPGS). Scu/TPGS were prepared using film solvent diffusion methods and characterized on the basis of their particle size, zeta potential, and drug encapsulation efficiency. Dynamic dialysis was used to study the release behavior of the polymeric micelles in vitro. Its pharmacokinetic characteristics and antithrombotic efficacy were studied by intravenous injection in rats. The results showed that Scu/TPGS were spherical, 20.09±2.62 nm in size and a slow release in vitro. The pharmacokinetic parameter T1/2 of Scu/TPGS was 762.12±46.56 min compared with commercial injection of 59.30±10.67 min (p<0.05). At the 1 mg/kg dose, the thrombolysis effect of micellar group was stronger than that of the commercial group (p<0.05). In conclusion, TPGS polymer micelles provided a valid strategy in chemotherapy for cerebrovascular diseases with poor water solubility and poor lipid solubility drugs such as scutellarin.

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1305-1312
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 44.

Tytuł:

Controversial advertising of medicines. A comparison between Poland and the United States

Autorzy:

Makowska, Marta

Powiązania:

https://bibliotekanauki.pl/articles/653027.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

pharmaceutical industry
advertisement
drugs
law
ethics

Opis:

For many years, the subject of aggressive marketing campaigns conducted by pharmaceutical companies has been raised in Poland. Drug ads are everywhere, on television, the radio, magazines and on the Internet. Therefore, it is extremely important is to ensure both their legal and ethical dimension. This article will present the differences between direct-to-consumer advertising of medicines in Poland and in the US. The dissimilarities result mainly from differences in legislation. In Poland, the law is much stricter than in the US. For example, in the United States companies are allowed to advertise prescription drugs directly to patients. In the whole of the European Union, and thus in Poland, it is strictly prohibited. The article will also present other regulations existing in Poland and in the United States and it will compare them. It will offer examples of violations of the law and ethics in the advertising of medicine in both countries. Lastly, it will briefly outline the negative consequences of unacceptable pharmaceutical marketing.

Źródło:

Annales. Etyka w Życiu Gospodarczym; 2018, 21, 5; 67-79
1899-2226
2353-4869

Pojawia się w:

Annales. Etyka w Życiu Gospodarczym

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 45.

Tytuł:

THE EUROPEAN MONITORING CENTRE FOR DRUGS AND DRUG ADDICTION - SELECTED SYSTEM-WIDE ISSUES AND ACTIVITIES

Autorzy:

Woch, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/915934.pdf

Data publikacji:

2018

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II

Tematy:

EU agency
drugs
Reitox
European Union

Opis:

The issue of drugs is an important problem for the European citizens and it poses a serious threat to safety and health of the European society. This is mainly due to the fact that one of the basic features characterizing the problem of drugs is its changeable and dynamic nature. Furthermore, the drug-related phenomena haveno borders, they exist everywhere where people live and affect all social classes. The European Union is one of the international organizations which, both by its own activities and the efforts of the member states, attempts to prevent and fight the adverse effects associated with drug abuse. The implementation of such a goal is possible thanks to the activities of the agency responsible for the holistic study of the problem of drugs and drug addiction and for popularization of the obtained information among the EU institutions, Member States and other organizations. The purpose of the article is to present the activities of the European Monitoring Centre for Drugs and Drug Addiction, whose role is to provide factual, objective, reliable and comparable information of the European standard on drugs and drug addiction as well as their effects both on the European Union itself andthe member states.

Źródło:

Review of European and Comparative Law; 2018, 34, 3; 41-57
2545-384X

Pojawia się w:

Review of European and Comparative Law

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 46.

Tytuł:

The problem of usage of drugs without prescriptions by the youth

Autorzy:

Szefczyk-Polowczyk, L.
Zygmunt, A.
Respondek, M.
Wengel, K.

Powiązania:

https://bibliotekanauki.pl/articles/2052446.pdf

Data publikacji:

2015

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

non-prescription drugs
self-treatment
OTC

Opis:

Introduction. Self-treatment, defined as application of drugs without prescription without consulting your doctor has become a common phenomenon. Easy access to this group of pharmaceutical. advertising campaigns and lack of awareness of adverse effects as a result of incorrect application makes drugs without prescription the medications which have become our first choice. The aim of the study is to assess the problem of the use of over the counter (OTC) drugs by young people living in the Silesian Voivodeship. Material and methods. The study included 180 persons from the Silesian voivodeship at the age of 18-30. The research tool was an author’s, anonymous questionnaire. The questions included within it concerned, among others: frequency, form and side effects of drugs applied without prescription. Results. Despite the fact that the majority of respondents (57%) assess their health state as good, the overwhelming number of people (91%) report applying medications without a prescription. The most popular OTC pharmaceutical products include painkillers and vitamins. One in five respondents (20%) admits that he or she consumes more medication than it is recommended in the package leaflet. Conclusions. Very good and good health state declared by the respondents does not exclude accepting their medication without prescription. In case of treatment of intermittent or mild symptoms, the use of medications without a prescription – saves patient’s time and unburdens health care system. This phenomenon, however, is a challenge for the public health sector. Actions must be undertaken which are aimed at raising consumers-patients’ awareness regarding the dangers posed by improper use of OTC drugs.

Źródło:

Health Problems of Civilization; 2015, 09, 1; 5-10
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 47.

Tytuł:

Procedural and non-procedural activities to reveal and secure drug substances

Autorzy:

Theuss, Patryk

Powiązania:

https://bibliotekanauki.pl/articles/45450973.pdf

Data publikacji:

2023-08-23

Wydawca:

Akademia Policji w Szczytnie

Tematy:

search
body search
drugs
forfeiture
evidence

Opis:

Combating drug crime is one of the most important challenges faced by law enforcement agencies in the modern world. The infamous popularity of prohibited substances, in particular amphetamine and marijuana, is due to its availability and reasonable price. Eliminating the indicated threat requires such diligent operational work from the law enforcement authorities and the comprehensive use of legal tools provided by the legislator. Taking appropriate steps, both procedural and non-procedural, leads to a factual conduct of criminal proceedings in the in rem and ad personam phase. In the presented article, the author analyzed the current legal status in terms of possible procedural and non-trial activities aimed at disclosing and securing prohibited substances. An important element of this publication is also an indication of activities aimed at collecting comprehensive evidence in accordance with the principle of material truth, which is a constitutive principle of criminal procedure. The conducted analysis leads to the conclusion that in global terms, combating drug crime is a measurable benefit not only in legal but also social, economic and sociological terms.

Źródło:

Przegląd Policyjny; 2023, 150(2); 365-375
0867-5708

Pojawia się w:

Przegląd Policyjny

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 48.

Tytuł:

Dopalacze – „legalne narkotyki” – substancje zagrażające życiu i zdrowiu – postawa administracji publicznej – zwalczanie czy kontrola?
Designer Drugs – “Legal Drugs” – Substances that Threaten Life and Health – the Attitude of Public Administration – Fighting or Controlling?

Autorzy:

Stasiak, Jarosław
Matyjek, Sebastian Konrad

Powiązania:

https://bibliotekanauki.pl/articles/50358888.pdf

Data publikacji:

2023

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

narkotyki
dopalacze
polityka narkotykowa
prawo karne
administracja publiczna
drugs
designer drugs
drug policy
criminal law
public administration

Opis:

Zjawisko narkomanii jest problemem globalnym, a walka z nim tradycyjnymi metodami opartymi na polityce zero tolerancji wydaje się być skazana na porażkę, czego przykładem są narkotyki projektowane, które miały być legalnymi analogami narkotyków konwencjonalnych. Celem niniejszej pracy jest próba odpowiedzi na pytanie, jak skutecznymi sposobami dysponuje państwo w walce z nowymi substancjami psychoaktywnymi, potocznie nazywanymi dopalaczami. Z treści pracy dowiadujemy się czym są dopalacze i jak ustawodawca pozycjonuje je pośród innych substancji narkotycznych, oraz jakimi metodami prowadzi z nimi walkę. Autorzy dokonują oceny skuteczności działania zaordynowanych przez ustawodawcę rozwiązań prawnych na gruncie prawa prywatnego i publicznego. Skutkiem powyższej oceny są postulaty konwalidacyjne kończące pracę.
The phenomenon of drug addiction is a global problem, and combating it with traditional methods based on a zero-tolerance policy seems doomed to failure, as exemplified by designer drugs, which were supposed to be legal analogues of conventional drugs. The aim of this study is to try to answer the question of how effective the state has in the fight against new psychoactive substances, commonly known as legal highs. From the content of the work, we learn what legal highs are and how the legislator positions them among other narcotic substances and what methods it uses to fight them. The authors evaluate the effectiveness of the legal solutions ordered by the legislator under private and public law. The result of the above assessment are the postulates of validation ending the work.

Źródło:

Acta Universitatis Lodziensis. Folia Iuridica; 2023, Numer specjalny: W trosce o godność, życie i zdrowie człowieka – zagadnienia administracyjnoprawne; 315-323
0208-6069
2450-2782

Pojawia się w:

Acta Universitatis Lodziensis. Folia Iuridica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 49.

Tytuł:

Insect natural products as potential source for alternative medicines - A Review

Autorzy:

Roy, Spandita
Saha, Sumana
Pal, Partha

Powiązania:

https://bibliotekanauki.pl/articles/1193952.pdf

Data publikacji:

2015

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Insects
alternative medicine
medicinal drugs
natural products

Opis:

Developments in bioengineering natural products from insects with potential use in modern medicines as well as in utilisation of insects as models for studying essential mammalian processes such as immune responses to pathogens are discussed in this review. The significant recent advances in developing insect derived natural products as potential new medicinal drugs and the use of medicinal plants for the treatment of human diseases has long been practised since the beginning of human civilization. To date, insects have been relatively neglected as sources of modern drugs although they have provided valuable natural products, including honey and silk, for at least 4-7000 years. The use of insect derived products as an alternative medicinal source is an exciting and rapidly expanding new field since insects are hugely variable and have a high biodiversity index. Insects products, such as silk and honey, have already been utilised commercially for thousands of years and extracts of insects used to produce for use in folk medicine around the world, nowadays several other insect products such as venoms which insects use for prey capture and defences, are also used to produce new medicinal drugs which are capable of fighting against a number of diseases like arthritis, inflammation, several cancers, neurological diseases and AIDS too. In the present decade the increasing price of biochemical medicines for the treatment of certain deadly diseases like cancer, AIDS etc is creating a huge economical burden to the common people in the developing countries like India. The search for alternative cost effective and easily available medicines for combating the upcoming diseases is an utmost need in the present decade. The emergence of this kind of alternative medicinal sources like that from the adult insects as well as from their different life history stages or their secretions which are available in plenty in the nature will open up new vistas in the recent researches based on development of medicinal drugs for human diseases.

Źródło:

World Scientific News; 2015, 19; 69-83
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 50.

Tytuł:

To treat or not to treat drug-refractory epilepsy by the ketogenic diet? That is the question

Autorzy:

Ułamek-Kozioł, Marzena
Pluta, Ryszard
Bogucka-Kocka, Anna
Czuczwar, Stanisław J.

Powiązania:

https://bibliotekanauki.pl/articles/989609.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

ketogenic diet
ketones
acetone
epilepsy
antiepileptic drugs

Opis:

Epilepsy is a serious neurologic disorder worldwide which affects about 1% of the population (ca. 50 million people), the highest prevalence occurring in both children and elderly. Apart from idiopathic forms, etiology of the disease involves multiple brain risk factors – the most frequent being cerebrovascular diseases, tumours and traumatic injuries. Several treatment options exist, including, for instance, pharmacotherapy, vagal nerve stimulation or epilepsy surgery. In spite of treatment, about 30% of patients with epilepsy still have seizures and become drug-refractory. This is why other treatment options may be recommended, and ketogenic diet seems a last-chance method, especially in children and adolescents with epilepsy. The diet contains high amounts of fat and low carbohydrates with vitamin supplementation. The elevated concentrations of ketones induced by the diet may result in inhibition of the synaptic activity of glutamate, the mammalian target of the rapamycin pathway, and activation of adenosine triphosphate-sensitive potassium channels. One of the main ketones is acetone, shown to increase the seizure threshold and potentiate the anticonvulsant activity of some antiepileptic drugs. The clinical effectiveness of the ketogenic diet has been confirmed in a number of clinical trials carried out mainly on children. A wider use of the ketogenic diet may be limited by the number of early adverse effects (gastrointestinal distress, acidosis, hypoglycaemia, dehydration and lethargy), and late adverse effects (hyperuricaemia, hyperlipidaemia, kidney stones, easy bruising, and decreases in height and weight). Recently, data are available on the negative impact of the ketogenic diet on the qualitative characteristics of lipoprotein subfractions which points to the atherogenic fenotype as a new side-effect. In conclusion, future research directed to the proper identification of patients (in terms of age, epilepsy type and duration, recommended antiepileptic drugs) is necessary to answer the title question.

Źródło:

Annals of Agricultural and Environmental Medicine; 2016, 23, 4
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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