Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "cytokine" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 23
Tytuł:
Origin of circulating acute phase cytokines: modified proteins may trigger il-6 production by macrophages. Preliminary report
Autorzy:
Koj, A
Guzdek, A.
Potempa, J.
Korzus, E.
Travis, J.
Powiązania:
https://bibliotekanauki.pl/articles/68989.pdf
Data publikacji:
1994
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
interleukin 6
macrophage
acute phase cytokine
cytokine
modified protein
glycated albumin
fibrinogen degradation product
modified serpin
Źródło:
Journal of Physiology and Pharmacology; 1994, 45, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Central single and chronic administration of morphine stimulates corticosterone and interleukin 9(IL)-6 in adjuvant-induced arthritis
Autorzy:
Zubelewicz, B.
Muc-Wierzgon, M.
Harbuz, M.S.
Brodziak, A.
Powiązania:
https://bibliotekanauki.pl/articles/69429.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
interleukin 6
arthritis
cytokine
corticosterone
morphine
central nervous system
neuroendocrine change
rat
hypothalamic-pituitary-adrenal axis
immune response
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 4,2
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Differential responses of hematopoietic and non-hematopoietic cells to anti-inflammatory cytokines: IL-4, IL-13 and IL-10
Autorzy:
Guzdek, A.
Stalinska, K.
Guzik, K.
Koj, A.
Powiązania:
https://bibliotekanauki.pl/articles/69534.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
non-hematopoietic cell
macrophage
interleukin 10
blood
hepatoma
antiinflammatory cytokine
in vitro
hematopoietic cell
interleukin 4
man
tumour necrosis factor-alpha
cytokine
interleukin 13
monocyte
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relation between expression of TNF alpha, iNOS, VEGF mRNA and development of heart failure after experimental myocardial infarction in rats
Autorzy:
Heba, G.
Krzeminski, T.
Porc, M.
Grzyb, J.
Dembinska-Kiec, A.
Powiązania:
https://bibliotekanauki.pl/articles/69900.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
nitric oxide synthase
tumour necrosis factor-alpha
cytokine
ischaemic myocardium
mRNA
thoracotomy
growth factor
rat
myocardial infarction
vascular endothelial growth factor
Źródło:
Journal of Physiology and Pharmacology; 2001, 52, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of p38 mitogen-activated protein kinase in the healing of gastric ulcers in rats
Autorzy:
Kabayashi, N.
Kataoka, T.
Ono, A.
Tsukimi, Y.
Okabe, S.
Powiązania:
https://bibliotekanauki.pl/articles/69658.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
ulcer
gastric ulcer
p38 kinase
cytokine
nitric oxide
angiogenesis
p38 mitogen-activated protein kinase
acetic acid
healing
rat
Źródło:
Journal of Physiology and Pharmacology; 2001, 52, 2
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interleukin-6 biology is coordinated by membrane bound and soluble receptors.
Autorzy:
Rose-John, Stefan
Powiązania:
https://bibliotekanauki.pl/articles/1043433.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
inflammation
cytokine
sgp130Fc fusion protein
gp130
cytokine receptor
soluble receptor
Opis:
Cytokine receptors exist in membrane bound and soluble form. Both forms bind their ligands with comparable affinity. While most soluble receptors are antagonists in that they compete for the ligands with their membrane counterparts, some soluble receptors are agonists. In this case, the complex of ligand and soluble receptor binds on target cells to a second receptor subunit and initiates signal transduction. Soluble receptors of the IL-6 family of cytokines are agonists. In vivo, the IL-6/soluble IL-6R complex stimulates several types of target cells not stimulated by IL-6 alone, since they do not express the membrane bound IL-6R. This process has been named transsignaling. We have shown that in several chronic inflammatory diseases like chronic inflammatory bowl disease, peritonitis and rheumatoid arthritis, transsignaling via the soluble IL-6R complexed to IL-6 is a crucial point in the transition from the acute to the chronic state of the disease. The mechanism by which the IL-6/ soluble IL-6R complex regulates the inflammatory state is discussed.
Źródło:
Acta Biochimica Polonica; 2003, 50, 3; 603-611
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma membrane rafts and chaperones in cytokine/ STAT signaling.
Autorzy:
Sehgal, Pravin
Powiązania:
https://bibliotekanauki.pl/articles/1043429.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytokine receptors
chaperones
fever
heat shock protein 90 (HSP90)
signal transducers and activators of transciption (STATs)
caveolin
lipid rafts
Opis:
We and others have recently obtained data suggesting that cytokine-STAT signaling in many different cell-types is a chaperoned pathway initiated at the level of specialized plasma membrane microdomains called "rafts" (the "raft-STAT signaling hypothesis"). These findings are of broad significance in that all cytokines and growth factors initiate signaling in target cells by interacting with respective cell-surface receptors. The new data suggest that raft microdomains represent the units of function at the cell-surface through which ligand-stimulated STAT signaling is initiated. Moreover, recent evidence shows the involvement of chaperone proteins in regulating the STAT signaling pathway. These chaperones include the human homolog of the tumorous imaginal disc 1 protein (hTid1) which associates with Janus kinase 2 (JAK2) at the level of the plasma membrane, heat shock protein 90 (HSP90) which associates with STAT3 and STAT1 proteins in caveolin-1-containing raft and cytoplasmic complexes, and glucose regulated protein 58 (GRP58/ER-60/ERp57), a thiol dependent protein-disulfide isomerase, found in association with STAT3 "statosome" complexes in the cytosol and in the raft fraction. We suggest a function of the HSP90 chaperone system in preserving IL-6/STAT3 signaling in liver cells in the context of fever. The identification and function of protein partners associated with specific STAT species in rafts and in cytosolic complexes, and in the efficient departure of cytokine-activated STATs from the cytosolic face of rafts towards the cell nucleus are now areas of active investigation.
Źródło:
Acta Biochimica Polonica; 2003, 50, 3; 583-594
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hookworm infections in human and laboratory animals - differences and similarities in immune responses
Autorzy:
Długosz, E.
Powiązania:
https://bibliotekanauki.pl/articles/2146399.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
laboratory animal
infection
man
cytokine
eosinophil
similarity
difference
hookworm
inflammation
antibody
immune response
Źródło:
Wiadomości Parazytologiczne; 2005, 51, 3; 219-225
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hookworm infections in human and laboratory animals - differences and similarities in immune responses
Autorzy:
Dlugosz, E
Powiązania:
https://bibliotekanauki.pl/articles/837842.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
laboratory animal
infection
man
cytokine
eosinophil
similarity
difference
hookworm
inflammation
antibody
immune response
Źródło:
Annals of Parasitology; 2005, 51, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bradykinin-related peptides up-regulate the expression of kinin B1 and B2 receptor genes in human promonocytic cell line U937
Autorzy:
Guevara-Lora, Ibeth
Florkowska, Magdalena
Kozik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1040550.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
inflammation
cytokine
kinin receptors
macrophage
kinins
Opis:
Kinins, universal mediators of inflammation, are recognized by two kinds of receptors, B1 and B2, which have been found to be expressed in numerous cell types of several species. However, the knowledge of the regulation of these receptors in leukocytes is still not satisfactory. In the current work, we have demonstrated a constitutive production of B2 receptor mRNA in the human promonocyte U937 cells and its two-fold augmentation after cell differentiation with retinoic acid and phorbol ester. Bradykinin and des-Arg10-kallidin induced the expression of both B2 and B1 receptors in cells before and after differentiation. Generally, the undifferentiated cells were more susceptible to bradykinin-dependent induction of kinin receptors (increases by approximately 250% and 200% for B2 and B1 receptors, respectively). The induction, by approx. 200%, of B1 receptor by des-Arg10-kallidin was detected on both mRNA and protein levels. In addition, an unexpected strong induction of B2 receptor by this compound was observed in the retinoic acid- and phorbol ester-differentiated cells (by 150% and 200%, respectively) that suggests a possible autoregulation of kinin receptors by own agonists during the inflammatory state. On the other hand, a strong enhancement of the expression of both receptors by interleukin 1β, especially in the phorbol ester-differentiated cells, indicates the involvement of kinin receptors in the propagation of the inflammatory processes.
Źródło:
Acta Biochimica Polonica; 2009, 56, 3; 515-522
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cathelicidin LL-37, granzymes, TGF-beta1 and cytokines levels in induced sputum from farmers with and without COPD
Autorzy:
Golec, M
Reichel, C.
Mackiewicz, B.
Skorska, C.
Curzytek, K.
Lemieszek, M.
Dutkiewicz, J.
Gora, A.
Ziesche, R.
Boltuc, J.
Sodolska, K.
Milanowski, J.
Spiewak, R.
Powiązania:
https://bibliotekanauki.pl/articles/49729.pdf
Data publikacji:
2009
Wydawca:
Instytut Medycyny Wsi
Tematy:
cathelicidin LL-37
peptide
chronic obstructive pulmonary disease
COPD zob.chronic obstructive pulmonary disease
sputum
farmer
human disease
organic dust
ELISA test
spirometric value
sputum sample
dust exposure
cytokine
lipopolysaccharide
Źródło:
Annals of Agricultural and Environmental Medicine; 2009, 16, 2; 289-297
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Do changes in iron metabolism contribute to the acceleration of the atherosclerosis process?
Autorzy:
Formanowicz, D.
Powiązania:
https://bibliotekanauki.pl/articles/80735.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
acceleration
atherosclerosis
cholesterol
chronic disease
coronary heart disease
inflammation
iron metabolism
lipid peroxidation
nitric oxide
oxidative stress
proinflammatory cytokine
risk factor
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Obesity and iron metabolism
Autorzy:
Zekanowska, E.
Boinska, J.
Giemza-Kucharska, P.
Kwapisz, J.
Powiązania:
https://bibliotekanauki.pl/articles/80448.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
adipocyte
adipose tissue
body fat
body mass index
child
endocrine organ
harmful effect
hepcidin
interleukin 1
interleukin 6
iron deficiency
iron homeostasis
iron metabolism
obesity
overweight
proinflammatory cytokine
tumour necrosis factor-alpha
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Occupational exposure to 50 Hz magnetic fields does not alter responses of inflammatory genes and activation of splenic lymphocytes in mice
Autorzy:
Luo, Xue
Jia, Shujie
Li, Renyan
Gao, Peng
Zhang, Yanwen
Powiązania:
https://bibliotekanauki.pl/articles/2177064.pdf
Data publikacji:
2015-09-24
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
mice
magnetic fields
inflammation
spleen
lymphocytes
cytokine
Opis:
Objectives The objective of the present study was to observe the effects of 50 Hz magnetic fields (MFs) on the immune function of splenic lymphocytes in mice. Material and Methods Twenty male Kunming mice (6 weeks old), weighing 18– 25 g, were randomly divided into sham exposure (N = 10) and 500 μT MFs (N = 10) groups. The mice in the MFs group were exposed to 500 μT MFs for 8 h daily (5 days/week) for up to 60 days. In vitro study was carried out to examine the effects of 50 Hz MFs on the expression of inflammatory factor genes and a cluster of differentiation 69 (CD69) in mouse prime splenic lymphocytes activated by para-Methoxyamphetamine (PMA) and ionomycin. In the in vitro experiments, lymphocytes were isolated from the spleen of 10 healthy Kunming mice, the cells were cultured in the Roswell Park Memorial Institute 1640 medium (RPMI-1640) and exposed to 0 μT, 250 μT, 500 μT, or 1 mT MFs in an incubator under 5% carbon dioxide (CO₂) at 37°C for 6 h. The levels of interleukin-2 (IL-2), IL-4, interferon-gamma (IFN-γ), GATA binding protein 3 (GATA-3) and T cell-specific T-box transcription factor (T-bet) were assessed by the real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR), respectively. The expression of CD69 was checked using the flow cytometry. Results Under our experimental conditions, body weight of the mice exposed to occupational, extremely low frequency- electromagnetic fields (ELF-EMFs) significantly decreased on day 20 and day 30. There were no significant changes observed in vivo in spleen weight, splenic coefficient, splenic histology profile and cytokine production in spleen tissues. Our in vitro experiments showed that 50 Hz MFs had no effect on the expression of these genes and CD69 to primary splenic cells. Conclusions In conclusion, under the applied experimental conditions, occupational exposure to 50 Hz magnetic field did not alter responses of inflammatory genes and activation of splenic lymphocytes in mice, except for body weight.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2016, 29, 2; 277-291
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 23

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies