- Tytuł:
- Merkel cell carcinoma
- Autorzy:
-
Markiewicz, Jarosław
Dziewirski, Wirginiusz - Powiązania:
- https://bibliotekanauki.pl/articles/1065725.pdf
- Data publikacji:
- 2014
- Wydawca:
- Medical Education
- Tematy:
-
Merkel cell carcinoma
cutaneous neuroendocrine carcinoma
therapy - Opis:
- Merkel cell carcinoma (MCC) is a rare cutaneous malignancy, with aggressive behaviour. The discovery of MCC polyomavirus (MCPyV) provided a major insight into pathogenesis of MCC, as MCPyV is present in most MCC tumours. The primary treatment of locoregional MCC is surgery, and sentinel lymph node biopsy should be performed in all cases at clinical stage I-II. Adjuvant radiotherapy decreases disease recurrences in stage I-III of the disease. Chemotherapy is primarily used for palliation and provides overall response rates of approximately 70%; however, the disease often recurs within a few months. All cases of MCC should be managed in an experienced multidisciplinary setting.
- Źródło:
-
OncoReview; 2014, 4, 3; A121-125
2450-6125 - Pojawia się w:
- OncoReview
- Dostawca treści:
- Biblioteka Nauki
Artykuł