Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "creatine kinase" wg kryterium: Temat

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-5 z 5
    Tytuł:
    The effect of hip dysplasia on some biochemical parameters, oxidative stress factors and hematocrit levels in dogs
    Autorzy:
    Polat, E.
    Han, M.C.
    Kaya, E.
    Yilmaz, S.
    Kayapinar, S.D.
    Coskun, S.
    Yildirim, A.
    Can, U.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087150.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    alkaline phosphatase
    hematocrit
    hip dysplasia
    creatine kinase
    oxidative stress
    Źródło:
    Polish Journal of Veterinary Sciences; 2021, 24, 4; 473-478
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Metabolic control analysis of integrated energy metabolism in permeabilized cardiomyocytes - experimental study
    Autorzy:
    Tepp, Kersti
    Timohhina, Natalja
    Chekulayev, Vladimir
    Shevchuk, Igor
    Kaambre, Tuuli
    Saks, Valdur
    Powiązania:
    https://bibliotekanauki.pl/articles/1040302.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cardiomyocytes
    creatine kinase
    metabolic control analysis
    respiration
    mitochondria
    Opis:
    The main focus of this research was to apply Metabolic Control Analysis to quantitative investigation of the regulation of respiration by components of the Mitochondrial Interactosome (MI, a supercomplex consisting of ATP Synthasome, mitochondrial creatine kinase (MtCK), voltage dependent anion channel (VDAC), and tubulin) in permeabilized cardiomyocytes. Flux control coefficients (FCC) were measured using two protocols: 1) with direct ADP activation, and 2) with MtCK activation by creatine (Cr) in the presence of ATP and pyruvate kinase-phosphoenolpyruvate system. The results show that the metabolic control is much stronger in the latter case: the sum of the measured FCC is 2.7 versus 0.74 (ADP activation). This is consistent with previous data showing recycling of ADP and ATP inside the MI due to the functional coupling between MtCK and ANT and limited permeability of VDAC for these compounds, PCr being the major energy carrier between the mitochondria and ATPases. In physiological conditions, when the MI is activated, the key sites of regulation of respiration in mitochondria are MtCK (FCC = 0.93), adenine nucleotide translocase ANT (FCC = 0.95) and CoQ cytochrome c oxidoreductase (FCC = 0.4). These results show clearly that under the physiological conditions the energy transfer from mitochondria to the cytoplasm is regulated by the MI supercomplex and is very sensitive to metabolic signals.
    Źródło:
    Acta Biochimica Polonica; 2010, 57, 4; 421-430
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis.
    Autorzy:
    Vyssokikh, Mikhail
    Brdiczka, Dieter
    Powiązania:
    https://bibliotekanauki.pl/articles/1043614.pdf
    Data publikacji:
    2003
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cytochrome c
    hexokinase
    free energy
    creatine kinase
    permeability transition pore
    Bax
    Opis:
    The outer mitochondrial membrane pore (VDAC) changes its structure either voltage-dependently in artificial membranes or physiologically by interaction with the adenine nucleotide translocase (ANT) in the c-conformation. This interaction creates contact sites and leads in addition to a specific organisation of cytochrome c in the VDAC-ANT complexes. The VDAC structure that is specific for contact sites generates a signal at the surface for several proteins in the cytosol to bind with high capacity, such as hexokinase, glycerol kinase and Bax. If the VDAC binding site is not occupied by hexokinase, the VDAC-ANT complex has two critical qualities: firstly, Bax gets access to cytochrome c and secondly the ANT is set in its c-conformation that easily changes conformation into an unspecific channel (uniporter) causing permeability transition. Activity of bound hexokinase protects against both, it hinders Bax binding and employs the ANT as anti-porter. The octamer of mitochondrial creatine kinase binds to VDAC from the inner surface of the outer membrane. This firstly restrains interaction between VDAC and ANT and secondly changes the VDAC structure into low affinity for hexokinase and Bax. Cytochrome c in the creatine kinase complex will be differently organised, not accessible to Bax and the ANT is run as anti-porter by the active creatine kinase octamer. However, when, for example, free radicals cause dissociation of the octamer, VDAC interacts with the ANT with the same results as described above: Bax-dependent cytochrome c release and risk of permeability transition pore opening.
    Źródło:
    Acta Biochimica Polonica; 2003, 50, 2; 389-404
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the effectiveness of training on a machine with a variable-cam
    Autorzy:
    Urbanik, C.
    Staniszewski, M.
    Mastalerz, A.
    Karczewska, M.
    Lutosławska, G.
    Iwańska, D.
    Madej, A.
    Ostrowska, E.
    Gwarek, L.
    Tkaczyk, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/307428.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    resistance training
    elbow flexors
    variable-cam
    creatine kinase
    trening
    łokieć
    mięśnie
    kreatyna
    kinaza
    Opis:
    The aim of the study was to assess the effectiveness of the training of elbow flexors through the use of 2 machines, one of which was equipped with a disc plate of constant radius, the other one with a variable-cam having a radius adjustable to muscle strength. The experiment included 45 men divided into 3 equal groups: training group A (variable-cam), training group B (circle), and control group C. The training lasted for 8 weeks, 3 times a week. In order to control the effects, the values of peak torque and power of the flexor muscles of the elbow were isokinetically measured for the angular velocities of 30°/s and 60°/s. Also taken were anthropometric measurements of the arm and the creatine kinase (CK) activity in the blood plasma. As a result of the training, significant increases of biomechanical values were noted only in group A: power increased over 20%, the peak torque over 14%. After the training, significant increases of arm circumference in the relaxed position were noted in group A (17 mm), as well as in group B (11 mm). Also, some changes in CK activity were observed between Monday and Friday in a training week. On the basis of the experimental measurements, it may be ascertained that training elbow flexor muscles on a machine with a variable-cam is more efficient for increases in strength and power, as well as for some anthropometric parameters, than training on a machine with a disc plate.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2013, 15, 4; 93-102
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Slaughter value, meat quality, creatine kinase activity and cortisol levels in the blood serum of growing-finishing pigs slaughtered immediately after transport and after a rest period
    Autorzy:
    Smiecinska, K.
    Denaburski, J.
    Sobotka, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/32050.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    slaughter value
    meat quality
    creatine kinase
    activity
    cortisol level
    blood serum
    growing-finishing animal
    pig
    animal transport
    cortisol
    physiological parameter
    Opis:
    The experimental materials comprised 44 hybrid [ (♀Polish Large White x Polish Landrace) x ♂Duroc] growing-finishing pigs. The animals were randomly divided into two groups: 24 pigs were slaughtered immediately after transport and 20 pigs were slaughtered after a 24-hour rest period in the lairage. The meat content of pork carcasses, carcass dressing percentage, the proximate chemical composition, physicochemical and sensory properties of meat and shear force values were determined. Serum creatine kinase activity and cortisol levels were determined in blood samples collected before transport and during carcass bleeding. Pigs slaughtered immediately after transport, compared with those slaughtered after a 24-hour rest period, were characterized by a higher meat content of the carcass and a higher carcass dressing percentage. Pre-slaughter handling had no effect on pork quality. The incidence of normal-quality meat, partially PSE (pale, soft, exudative) meat and PSE meat was similar in both groups. Chemical analysis showed that the content of dry matter, total protein, fat and minerals in meat was comparable in both groups. As regards the functional properties of the pork, samples from the carcasses of pigs that had rested before slaughter had a higher contribution of the red color component. Meat from pigs slaughtered immediately after transport had more desirable sensory properties. Pre-slaughter resting had a significant effect on those analyzed physiological parameters which were found to be good indicators of pre-slaughter stress. Serum creatine kinase activity and cortisol levels were higher in blood samples collected after transport (during carcass bleeding) than in samples collected before transport, pointing to a strong stress response of animals to pre-slaughter treatment. The decrease in serum cortisol levels in blood samples collected during bleeding from the carcasses of pigs slaughtered after a 24-hour rest period, compared with samples collected from animals slaughtered immediately after transport, suggests that rest before slaughter alleviated stress induced by pre-slaughter handling operations.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies