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Wyszukujesz frazę "congenital" wg kryterium: Temat


Tytuł:
Evaluation of the surgical treatment for congenital blepharoptosis using Mustarde’s modified method
Autorzy:
Iljin, Aleksandra
Zieliński, Andrzej
Lewandowicz, Edward
Antoszewski, Bogusław
Zieliński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1394152.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
congenital blepharoptosis
surgical treatment
Opis:
The aim of the study was evaluation of the results of surgical treatment of congenital blepharoptosis (CBP) using Mustarde’s modified method. Material and methods. Between 2005-2014 forty eight children with CBP underwent surgical correction of CBP by Mustarde’s modified method. Basing on the results of ophthalmic and orthoptic examination, and standard measurements, we estimated postoperative difference in the position and symmetry of the upper eyelids, and postoperative complications in our patients. Results. Very good results were obtained in all cases with mild, in 89.5% with moderate, and in 85.7% with severe unilateral CBP after correction by Mustarde’s modified method. Lagophthalmos was seen in 6.25%, and undercorrection in 12.5% of cases. Conclusions. 1. Mustarde’s modified method allows for obtaining very good functional and aesthetic results in CBP patients. 2. Mustarde’s modified method is a valuable supplemental surgical technique in CBP, and contributes to a low rate and small range of lagophthalmos.
Źródło:
Polish Journal of Surgery; 2016, 88, 3; 155-159
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of Adriblastin and Bleomycin on Wistar rat mothers and fetus development
Autorzy:
Sęk-Mastej, Anna
Galiniak, Sabina
Krawczyk-Marć, Izabela
Balawender, Krzysztof
Szymczak, Artur
Kaniewski, Maciej
Leksa, Natalia
Biesiadecki, Marek
Orkisz, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/454733.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
pregnancy
foetus
congenital defect
teratogen
Opis:
Introduction. Gestation is a very sensitive time both to mother and child. Any substance, factor, or environmental condition disturbing homeostasis may cause congenital defects, anomalies or even death. Teratology evaluates those potential factors and their influence. Also, medicinal products used during pregnancy may be teratogenic. Adriblastin, also known as Doxorubicin, and Bleomycin are widely used cytostatic drugs in oncology. Aim. Aim of this study was to evaluate the embryotoxic effects of Doxorubicin and Bleomycin in an animal model. Materials and methods. Fertilised Wistar rat females were given each drug intraperitoneally between the 8th and 15th gestation day, and compared to control group receiving placebo (distilled water, 0.9% NaCl). Another group received acetyl salicylic acid, as a model, well known teratogen. Changes in mothers’ weight from baseline, implantation of embryos, any discrepancies in mothers wombs and health as well as defects in fetuses were evaluated and compared. Fetus skeletons were stained by Dowson’s method to visualise bone defects. Results and conclusion. Both Adriblastin and Bleomycin were teratogenic, producing significantly more embryo absorptions, and fetal defects compared to placebo. The effects of the two cytostatics were similar to the model teratogen acetyl salicylic acid.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 2; 85-91
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bochdalek hernia in an adult female with intrathoracic left kidney and splenic flexure of the colon: a rare case report with literature review
Autorzy:
Kumar, Navin
Gupta, Amit
Rajput, Deepak
Powiązania:
https://bibliotekanauki.pl/articles/1391786.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
congenital diaphragmatic hernia
diaphragmatic hernia
Opis:
Congenital diaphragmatic hernia (CDH) is extremely rare in adults. Bochdalek hernia (BH) is the most common one among all congenital diaphragmatic hernias. This is due to incomplete fusion of pleuroperitoneal folds during early fetal development. It remains asymptomatic in many adults. It usually occurs on the left side and is common in males (62%). Open or laparoscopic surgical repair is the treatment of choice. We reported on a rare case of BH in an adult female with intra-thoracic left kidney and splenic flexure of the colon, who presented with non-specific abdominal symptoms. Key message: BH in adults is usually present with vague abdominal symptoms. We advocate the use of the CECT scan of the abdomen in the management of all cases with non-specific abdominal symptoms.
Źródło:
Polish Journal of Surgery; 2020, 92, 2; 60-63
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Intrauterine fetal surgery
Autorzy:
Barbachowska, Aleksandra
Baliś, Mikołaj
Krzanik, Klaudia
Zamłyński, Mateusz
Bodzek, Piotr
Olejek, Anita
Powiązania:
https://bibliotekanauki.pl/articles/1179515.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
congenital disorders
fetoscopy
perinatology
prenatal diagnosis
Opis:
The progress made in the past few years in prenatal medicine has led to the development of new diagnostic and surgical techniques that are used to treat congenital disorders during pregnancy. This stride also raises ethical questions, including the borderline between innovative treatment and experimental surgery. Surgical interventions on the fetus may be performed by amniotic shunting, open fetal surgery or fetoscopy. The choice of the method depends on the type of malformation. Intrauterine surgery is possible in selected cases e.g. congenital cystic adenomatoid malformation, diaphragmatic hernia, hydrocephalus, myelomeningocele, feto-fetal transfusion syndrome and others. The indications for fetal intervention are: the risk of fetal death, significant developmental disorders or the chance for reducing the disability. Both, amniotic shunting and fetoscopy, are performed by gynecologists, whereas open fetal surgeries require cooperation between gynecologists, pediatric surgeons and other medical specialists. Parents are informed about congenital defects, prognosis and treatment possibilities. Afterwards they discuss the treatment plan with doctors. Prenatal procedures are still relatively rare and require long-term observation, refinement in surgical techniques and guidelines for postoperative care. Current research focuses on gene therapy and use of stem cells in developmental defects treatment.
Źródło:
World Scientific News; 2017, 76; 5-15
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paternal occupational exposures and the risk of congenital malformations — A case-control study
Autorzy:
El-Helaly, Mohamed
Abdel-Elah, Kamal
Haussein, Ayman
Shalaby, Hend
Powiązania:
https://bibliotekanauki.pl/articles/2185358.pdf
Data publikacji:
2011-06-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
paternal
occupational exposure
congenital malformation
risk
Opis:
Objectives: This study examined the association between certain paternal occupational exposures during the periconceptional period and the risk of congenital malformations. Materials and Methods: A case-control study was carried out from December 2009 to April 2010; on 242 congenital malformation cases and 270 controls. Paternal occupational exposure to certain workplace hazards was assessed by a detailed questionnaire to evaluate the occupational exposure for both fathers and mothers including pesticides, solvents, welding fumes, lead, working with video display terminals (VDTs) and computer monitors. In addition, the questionnaire assessed the presence of other risk factors such as consanguinity, smoking and history of any maternal diseases during the pregnancy with the child. Results: The results revealed that the odds of having a child with congenital malformation was higher (P < 0.01) if the father was occupationally exposed to pesticides (OR: 3.42, 95% CI: 1.97-5.92), solvents (OR: 5.63, 95% CI: 2.77-11.42), or welding fumes (OR: 2.98, 0.99-8.54) during the periconceptional period. However, consanguinity (OR: 1.91, 95% CI: 1.25-2.92) was a risk factor of developing congenital malformations among offspring. Conclusion: Control of workplace exposures and adherence to threshold limit values of those hazards should be adopted to minimize the risk of developing congenital malformations among offspring.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2011, 24, 2; 218-227
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical treatment in children with otosclerosis and congenital stapes fixation: our experience and outcome
Autorzy:
Sobolewska, Aleksandra
Clarós, Pedro
Powiązania:
https://bibliotekanauki.pl/articles/1397795.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
stapedotomy
stapes surgery
congenital stapes fixation
congenital stapes ankylosis
juvenile otosclerosis
children
pediatric stapes surgery
Opis:
Aim: To evaluate outcomes of stapes surgery in children with congenital stapes fixation and juvenile otosclerosis. Methods: A retrospective chart review was performed from 1987 to 2013 to identify patients under 18 years old who underwent a stapes surgery. Patients' age, gender, pre- and postoperative audiograms, intraoperative findings including aetiology of stapes fixation, prosthesis type, and complications were analysed. Results: 18 children (6 - 17 years old), all with bilateral conductive hearing loss were identified and 34 stapes surgeries were performed (two patients underwent surgery only on one side). The cause of fixation included juvenile otosclerosis in 88% and congenital stapes fixation in 12%. The mean pre-operative air-bone gap (ABG) was 36,24 dB (SD: 10,86) compared to a postoperative mean ABG of 7,74 (SD: 3,3) (p < 0.000). The profound sensorineural hearing loss was not observed in long-term follow-up. Conclusions: Paediatric stapes surgery has comparable results to stapedectomy in adults regardless of the cause of stapes fixation; however, the better hearing outcome was observed for cases of juvenile otosclerosis rather than congenital stapes fixation.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 2; 23-28
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Morphometric and cytological disturbances of pancreatic islets evoked by congenital portosystemic shunt in dogs
Autorzy:
Frymus, J.
Trębacz, P.
Sobczak-Filipiak, M.
Czopowicz, M.
Galanty, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087140.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
congenital portosystemic shunt
dogs
pancreatic islets
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 4; 465-471
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical treatment of a nasal dermoid cyst: open rhinoplasty
Autorzy:
Yurochko, Fedir
Olashyn, Vasyl
Kopanska, Dzvenyslava
Powiązania:
https://bibliotekanauki.pl/articles/1399458.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
congenital nasal masses
dermoid cyst
open rhinoplasty
Opis:
Introduction: Dermoid cysts (or dermoids) are benign tumors which belong to choristoma group (teratoma). Nasal dermoid cysts (NDCs) are the most common congenital defect of the nasal midline. The diagnosis is usually established at an early age - mainly by the age of 3. Due to late diagnosis and/or delay of surgical treatment, facial deformities, recurrent infections (festering of cysts or subcutaneous infections), nasal blockage or intracranial complications may occur. Case report: This paper presents a clinical case of a 7-year-old boy admitted to the ENT department of the Lviv Regional Children’s Clinical Hospital „OHMATDYT” with symptoms of ongoing pain, swelling and caseous discharge from the fistulous tract on the nasal bridge. Diagnostic MRI showed a bone-shaped structure in the subcutaneous tissue of the nasal bridge. After evaluation, the dermoid cyst was successfully treated surgically with open rhinoplasty. No complaints were reported during the 2-year post-operative period. Conclusions: NDC is a subcutaneous cyst, which derives from the ectoderm and mesoderm. In addition to clinical signs, the radiological imaging methods – CT and MRI – are crucial for NDC diagnosis. The effective method of NDC treatment is radical surgical resection.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 2; 49-53
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency – management and differentiation in adults
Autorzy:
Nowak, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1066263.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
21-hydroxylase
androgens
congenital adrenal hyperplasia
glucocorticosteroids
Opis:
Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is one of the most common autosomal recessive hereditary diseases. The lack of cortisol synthesis leads to excessive stimulation of the adrenal glands by adrenocorticotropic hormone (ACTH). Moreover the impairment of cortisol synthesis results in adrenal hyperplasia and excessive androgen synthesis. Congenital adrenal hyperplasia is characterised by a considerable correlation between the genotype and the phenotype with the type of CYP21A2 gene mutation affecting the severity of 21-hydroxylase deficiency. The clinical manifestations of congenital adrenal hyperplasia in adults result from adrenocortical insufficiency, hyperandrogenism, and the adverse effects of glucocorticosteroids, which are used for the treatment of the syndrome. Non-classic congenital adrenal hyperplasia may sometimes have no clinical manifestation. Patients with classic congenital adrenal hyperplasia experience a wide variety of symptoms, including obesity, hypertension, hyperinsulinaemia, insulin resistance, and hyperleptinaemia. These abnormalities, the same as glucocorticosteroid treatment, promote the development of other diseases, such as metabolic syndrome, diabetes mellulitis, cardiovascular diseases and psychosocial problems. Moreover glucocorticosteroids treatment increases risk of osteoporosis and dermatological disorders. The maladies are more often seen in patients suffering from congenital adrenal hyperplasia syndrome than in the general population. Patients suffering from congenital adrenal hyperplasia require systematic evaluation of biochemical parameters (17-hydroxyprogesterone and androstendion) the same as clinical parameters (body mass index, waist circumference, glucose, lipids, blood pressure). Medical care for patients suffering from congenital adrenal hyperplasia should be provided by reference centres. Patients require cooperation between an endocrinologist, diabetologist, gynaecologist, andrologist, urologist, sexuologist and psychologist.
Źródło:
World Scientific News; 2019, 130; 71-81
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Congenital cholesteatomas
Autorzy:
Narożny, Waldemar
Kuczkowski, Jerzy
Stankiewicz, Czesław
Powiązania:
https://bibliotekanauki.pl/articles/1401793.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
congenital cholesteatoma
middle ear
etiology
treatment
overview
Opis:
Congenital cholesteatoma is a rare ear disorder. The most common presentation is a pearly and white mass, visible with an intact tympanic membrane in individuals with no previous history of ear discharge, ear surgery or perforation of tympanic membrane. Based on a careful overview of literature, authors of this article present: the most probable theories of the cause of development of congenital cholesteatoma, diagnostic criteria of congenital cholesteatoma, its most common clinical symptoms, preoperative studies, methods of surgical treatments and goals of postoperative proceedings. Furthermore, authors present a comparison of histological, molecular and clinical features of congenital and acquired cholesteatomas.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2015, 4, 2; 78-83
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Non-invasive assessment of haemodynamic parameters in patients after Fontan procedure
Autorzy:
Gutknecht, P.
Kwiatkowska, J.
Wałdoch, A.
Siebert, K.
Siebert, J.
Powiązania:
https://bibliotekanauki.pl/articles/2085957.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
congenital heart disease
Fontan circulation
impedance cardiography
haemodynamics
Opis:
Introduction and objective. Single ventricle anomaly is one of the complex congenital heart defects. A dependable non-invasive method of evaluation of Fontan circulation haemodynamics for early diagnosing unstable patients is hardly available in routine clinical practice. The aim of the study is non-invasive evaluation of the haemodynamic parameters in patients after Fontan operation. Materials and method. The study involved 11 participants (age 24.4±4.3 years) with functionally univentricular hearts after Fontan operation. Evaluation of haemodynamic parameters was performed in supine and sitting positions using the impedance cardiography method. Results. In comparative analysis, heart rate (70.1 vs.78.3 1/min; p=0.001), diastolic blood pressure (73.9 vs. 76.7 mm Hg; p=0.026), mean arterial blood pressure (84.5 vs. 88.0 mm Hg; p=0.013), systemic vascular resistance (1284.8 vs. 1334.9 dyn*s*cm-5; p=0.024), systemic vascular resistance index (2178.7 vs. 2272.8 dyn*s*cm-5*m2; p=0.018), pre-ejection period (124.2 vs. 136.2 ms; p=0.009), systolic time ratio (0.43 vs. 0.53; p=0.0001), and Zo (26.2 vs. 28.7 Ω; p<0.00001), were significantly higher in the sitting position. Stroke volume (75.4 vs. 68.5 ml; p=0.013), stroke index (42.7 vs. 39.0 ml*m-2; p=0.014), thoracic fluid content (38.5 vs. 35.4 1*kΩ-1; p=<0.00001), thoracic fluid content index (22.8 vs. 21.0 1*kΩ-1*m-2; p=<0.00001), and left-ventricular ejection time 291.1 vs. 260.1 ms; p=<0.00001, were significantly higher in the supine position. Conclusions. In patients after Fontan procedure, impedance cardiography can be a useful tool the assessment of shortterm haemodynamic changes provoked by postural changes. Its clinical value in patients with congenital heart defects should be further investigated.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 384-387
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Therapy of congenital glaucoma
Autorzy:
Grehn, Franz
Hoffmann, Esther
Powiązania:
https://bibliotekanauki.pl/articles/1927525.pdf
Data publikacji:
2020
Wydawca:
Medical Education
Tematy:
aphakic glaucoma
congenital glaucoma
goniotomy
trabeculotomy
tube implantation
Opis:
The primary therapy of all forms of primary and secondary congenital glaucoma is surgical. In the last few decades, the options for customized surgical approach to different types of childhood glaucoma have significantly developed. In particular, circumferential trabeculotomy has shown some superiority over conventional trabeculotomy and is now also used to treat secondary congenital glaucoma. Goniotomy is still a valid alternative. Tube implants in childhood glaucoma still need
Źródło:
OphthaTherapy; 2020, 7, 3; 232-238
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Congenital adrenal hyperplasia: clinical symptoms and diagnostic methods
Autorzy:
Podgórski, Rafał
Aebisher, David
Stompor, Monika
Podgórska, Dominika
Mazur, Artur
Powiązania:
https://bibliotekanauki.pl/articles/1038519.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Congenital Adrenal Hyperplasia
CAH
steroidogenesis
21-hydroxylase deficiency
Opis:
The aim of this paper is a straightforward presentation of the steroidogenesis process and the most common type of congenital adrenal hyperplasia (CAH) - 21-hydroxylase deficiency - as well as the analytical diagnostic methods that are used to recognize this disease. CAH is a family of common autosomal recessive disorders characterized by impaired adrenal cortisol biosynthesis with associated androgen excess due to a deficiency of one or more enzymes in the steroidogenesis process within the adrenal cortex. The most common and prototypical example of the CAH disorders group (90-95%) is caused by 21-hydroxylase deficiency. Less frequent types of CAH are 11β-hydroxylase deficiency (up to 8% of cases), 17α-hydroxylase deficiency, 3β-hydroxysteroid dehydrogenase deficiency, P450 oxidoreductase deficiency and StAR deficiencies. In the 21-hydroxylase and 11β-hydroxylase deficiency, only adrenal steroidogenesis is affected, whereas a defect in 3β-hydroxysteroid dehydrogenase or 17α-hydroxylase also involves gonadal steroid biosynthesis. Many countries have introduced newborn screening programs based on immunoassays measuring 17-hydroxyprogesterone from blood spots used for other neonatal screening tests which enable faster diagnosis and treatment of CAH. Currently, chromatographic techniques coupled with mass spectrometry are gaining popularity due to an increase in the reliability of the test results.
Źródło:
Acta Biochimica Polonica; 2018, 65, 1; 25-33
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Congenital incomplete bowel rotation: an exceptionally rare case of incomplete bowel rotation in an adult patient presenting with symptoms of gastrointestinal obstruction
Autorzy:
Rachel, Franciszek
Łapiński, Andrzej
Szczerba, Dariusz
Gutterch, Krystian
Powiązania:
https://bibliotekanauki.pl/articles/1393568.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
Congenital incomplete bowel rotation
obstruction
Ladd’s procedure
Opis:
The authors report a case of a 21-year-old patient with incomplete bowel rotation presenting with symptoms of chronic obstruction of the upper gastrointestinal tract and the diagnostic difficulties posed by the presented case. The decisive diagnostic examination consisted in an abdominal CT scan with contrast administration. The patient was successfully treated by means of Ladd's procedure.
Źródło:
Polish Journal of Surgery; 2017, 89, 3; 44-47
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of lumbosacral transitional vertebrae in dogs in Berlin
Autorzy:
Gong, H.
Slunsky, P.
Klass, L.G.
Brunnberg, L.
Powiązania:
https://bibliotekanauki.pl/articles/2087324.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
radiology
congenital disease
breed health
hip dysplasia
cauda equina
Źródło:
Polish Journal of Veterinary Sciences; 2020, 23, 2; 261-265
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł

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