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Tytuł:
Computer aided methods for stability analysis of 2D linear systems described by the first Fornasini-Marchesini model
Autorzy:
Ruszewski, A.
Busłowicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/384998.pdf
Data publikacji:
2014
Wydawca:
Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów
Tematy:
2D system
linear, discrete
stability
computational method
Opis:
Computer aided methods for investigation of the asymptotic stability of 2D discrete linear systems described by the first Fornasini-Marchesini model are given. The methods require computation of eigenvalues of complex matrices or values of complex functions. Effectiveness of the stability tests are demonstrated on numerical examples.
Źródło:
Journal of Automation Mobile Robotics and Intelligent Systems; 2014, 8, 2; 3-8
1897-8649
2080-2145
Pojawia się w:
Journal of Automation Mobile Robotics and Intelligent Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Guidelines for micro- and mesoscale computer modelling of fluid in flows in the soil-root system
Założenia dla modelowania komputerowego w mikro- i mezoskali przepływów płynów w systemie gleba-korzeń
Autorzy:
Vogelgesang, J.
Molenda, K.
Wacięga, M.
Powiązania:
https://bibliotekanauki.pl/articles/287033.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Inżynierii Rolniczej
Tematy:
przepływ
gleba
metoda obliczeniowa
model komputerowy
flow
soil
computational method
computer model
Opis:
Fluid flows in the soil, in the plant root zone, are linked with many phenomena, which may be considered in several scales. Interdisciplinary, complex knowledge explaining these phenomena in micro- and mesoscale may be effectively used in a computer model simulating the flow. The work constitutes a preliminary analysis of possibilities for implementation of this project. The researchers have pointed out promising computational methods (MD, SPH, LG), which are employed in similar problems. These methods are available in some flow-simulating applications, however they are not soil environment-oriented. Difficulties in adaptation are brought about by the number of phenomena, complicated material and geometrical structure of soil, and changes in this structure generated by flow. Model framework is planned to be based on three object groups: soil, fluids, plant roots. The model should be open, allowing to make extensions through introducing new components and modules, e.g. new soil constituents, and methods describing their behaviour in the aspect of flow.
Przepływy płynów w glebie, w strefie przykorzennej roślin, są związane z wieloma zjawiskami, które można rozpatrywać w kilku skalach. Interdyscyplinarna, złożona wiedza objaśniająca te zjawiska w mikro- i mezoskali może być efektywnie wykorzystana w modelu komputerowym symulującym przepływ. Praca jest wstępną analizą możliwości realizacji takiego projektu. Wskazano na obiecujące metody obliczeniowe (MD, SPH, LG), które są wykorzystywane w zbliżonych zagadnieniach. Metody te udostępnia kilka programów symulujących przepływ, niemniej nie są one ukierunkowane na środowisko glebowe. Trudności adaptacji wnosi liczba zjawisk, skomplikowana struktura materialna i geometryczna gleby, oraz zmiany tej struktury na skutek przepływu. Szkielet modelu zamierza się oprzeć o trzy grupy obiektów: glebę, płyny, korzenie roślin. Model powinien posiadać charakter otwarty, pozwalający na rozszerzenia przez wprowadzanie nowych komponentów i modułów, np. nowych składników gleby jak i metod opisujących ich zachowania w aspekcie przepływu.
Źródło:
Inżynieria Rolnicza; 2010, R. 14, nr 6, 6; 113-120
1429-7264
Pojawia się w:
Inżynieria Rolnicza
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Integration of experimental and computational methods for identifying geometric, thermal and diffusive properties of biomaterials
Autorzy:
Weres, J.
Kujawa, S.
Olek, W.
Czajkowski, L.
Powiązania:
https://bibliotekanauki.pl/articles/25176.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:
experimental method
computational method
identification
geometrical property
thermal property
diffusive property
biomaterial
heat transport
water transport
agro-food product
forest product
Źródło:
International Agrophysics; 2016, 30, 2
0236-8722
Pojawia się w:
International Agrophysics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Accumulative information enhancement in the self-organizing maps and its application to the analysis of mission statements
Autorzy:
Kitajima, R.
Kamimura, R.
Powiązania:
https://bibliotekanauki.pl/articles/91614.pdf
Data publikacji:
2015
Wydawca:
Społeczna Akademia Nauk w Łodzi. Polskie Towarzystwo Sieci Neuronowych
Tematy:
information
neural systems
computational method
artificial data set
mission
statement
informacja
systemy neuronowe
metoda obliczeniowa
zbiór danych
misja
komunikat
Opis:
This paper proposes a new information-theoretic method based on the information enhancement method to extract important input variables. The information enhancement method was developed to detect important components in neural systems. Previous methods have focused on the detection of only the most important components, and therefore have failed to fully incorporated the information contained in the components into learning processes. In addition, it has been observed that the information enhancement method cannot always extract input information from input patterns. Thus, in this paper a computational method is developed to accumulate information content in the process of information enhancement. The method was applied to an artificial data set and the analysis of mission statements. The results demonstrate that while we were able to explicitly extract the symmetric properties of the data from the artificial data set, only one main factor was able to be extracted from the mission statement, namely, “contribution to the society”. The companies with higher profits tend to have mission statements concerning the society. The results can be considered to be a first step toward the full clarification of the importance of mission statements in actual business activities.
Źródło:
Journal of Artificial Intelligence and Soft Computing Research; 2015, 5, 3; 161-176
2083-2567
2449-6499
Pojawia się w:
Journal of Artificial Intelligence and Soft Computing Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The impact of wheel spacing on allowable force applied to the axis of the agricultural vehicle
Wpływ rozstawu kół na dopuszczalną siłę obciążającą oś pojazdu rolniczego
Autorzy:
Nowowiejski, R.
Dawidowski, J. B.
Janicki, W.
Powiązania:
https://bibliotekanauki.pl/articles/93855.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Inżynierii Rolniczej
Tematy:
agricultural vehicle
twin-wheels
allowable axis load
twin-wheelbase
computational method
pojazd rolniczy
koło bliźniacze
dopuszczalne obciążenie osi
rozstaw kół bliźniaczych
metoda obliczeniowa
Opis:
The objective of the study was to develop computational methods for determination of the impact of the twin-wheels (their positioning along the axis) and soil conditions, specified by the stress concentration factor, on the limit values of the forces loading the axis of the agriculture vehicle, thus reducing the risk of excessive soil compaction. The formula of Boussinesqu (1885) supplemented by Fröhlich (1934) with the stress concentration factors was used. The values of the limit force were determined by adopting assumptions that wheels loaded soil surface in points and stress caused in soil should not exceed its agro-technical bearing capacity defined by the value of the limiting stress. The developed method allows setting the limit value of twin-wheelbase, at which the effect of adjoining force onto stress in soil semi-space fades away. This means that through a relatively small change of a wheelbase, it is possible to achieve more convenient conditions of load transfer on soil, in the context of the risk reduction of excessive soil compaction. The proposed method enables to construct diagrams for calculation of allowable axis load on the base of the known value of stress within the soil profile which determine its agro-technical capacity.
Celem pracy było opracowanie metody obliczeniowej do określania wpływu rozstawu kół bliźniaczych (ich rozsunięcia na osi) i warunków glebowych, określonych współczynnikiem koncentracji naprężenia, na wartości dopuszczalnych sił obciążających oś pojazdu rolniczego, zmniejszających ryzyko nadmiernego zagęszczania gleb. Wykorzystano przy tym formułę Boussinesqu (1885) uzupełnioną przez Fröhlicha o współczynniki koncentracji naprężenia (1934). Wartości sił dopuszczalnych wyznaczono przyjmując założenia punktowego obciążenia powierzchni gleby przez koła a wywołane nimi w glebie naprężenia nie powinny przekraczać jej agrotechnicznej nośności, określonej wartością naprężenia granicznego. Opracowana metoda pozwala wyznaczać graniczną wartość rozsunięcia kół bliźniaczych, przy której zanika wpływ siły sąsiadującej na naprężenia w półprzestrzeni glebowej. Oznacza to, że poprzez stosunkowo niewielką zmianę rozstawu możliwe jest osiąganie dogodniejszych warunków przenoszenia obciążenia na glebę, w kontekście ograniczania ryzyka nadmiernego zagęszczania gleby. Zaproponowana metoda umożliwia wykonanie nomogramów do określania dopuszczalnego obciążenia osi pojazdu na podstawie znajomości wartości naprężenia w glebie, wyznaczającego jej agrotechniczną nośność.
Źródło:
Agricultural Engineering; 2015, 19, 4; 91-100
2083-1587
Pojawia się w:
Agricultural Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zbrojenie konstrukcji betonowych niemetalicznymi prętami kompozytowymi FRP
Reinforcing concrete structures with non-metallic composite FRP bars
Autorzy:
Grygo, R.
Kosior-Kazberuk, M.
Powiązania:
https://bibliotekanauki.pl/articles/402765.pdf
Data publikacji:
2017
Wydawca:
Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:
pręt zbrojeniowy typu FRP
konstrukcja zbrojona
właściwości mechaniczne
badanie doświadczalne
metoda obliczeniowa
reinforcing bar type FRP
reinforced construction
mechanical properties
experimental study
computational method
Opis:
W artykule przedstawiono rodzaje, właściwości i metody określania cech mechanicznych zbrojeniowych prętów kompozytowych FRP. Na podstawie analizy wyników badania właściwości wytrzymałościowych prętów z włóknem szklanym GFRP i prętów z włóknem bazaltowym BFRP zaprezentowano metody określania gwarantowanej wytrzymałości na rozciąganie i gwarantowanego modułu sprężystości zbrojenia niemetalicznego według standardów ACI 440.1R oraz CSA-S807. Jako przykład procedury projektowania elementu betonowego zbrojonego prętami FRP omówiono metodę obliczania nośności na zginanie według ACI 440.1R. Do obliczeń wykorzystano wyniki badań właściwości mechanicznych prętów GFRP i BFRP.
The paper presents the sorts, properties and designing methods for structures with FRP bars. The methods to determine the guaranteed tensile strength and guaranteed modulus of elasticity according to the guidelines for non-metallic reinforcement ACI 440.1R and CSA-S807 were presented, based on the analysis of strength parameters test results of GFRP bars and BFRP bars. As an example, the procedure of calculating the flexural capacity of structure reinforced with FRP bars according to ACI 440.1R was discussed. The results of the mechanical properties tests of GFRP bars and BFRP bars were used for calculation.
Źródło:
Budownictwo i Inżynieria Środowiska; 2017, 8, 1; 21-28
2081-3279
Pojawia się w:
Budownictwo i Inżynieria Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Estimation of stochastic traffic capacity using extreme value theory and censoring: a case study in Salem, New Hampshire
Autorzy:
Laflamme, E. M.
Ossenbruggen, P. J.
Powiązania:
https://bibliotekanauki.pl/articles/224150.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
stochastic capacity
estimation of traffic
daily flow maxima
capacity distribution function
censoring
computational Bayesian method
przepustowość ruchu
szacowanie ruchu
metoda bayesowska
Opis:
In this work, we introduce a method of estimating stochastic freeway capacity using elements of both extreme value theory and survival analysis. First, we define capacity data, or estimates of the capacity of the roadway, as the daily maximum flow values. Then, under a survival analysis premise, we introduce censoring into our definition. That is, on days when flows are sufficiently high and congestion occurs, corresponding flow maxima are considered true estimates of capacity; otherwise, for those days that do not observe high flows or congestion, flow maxima are deemed censored observations and capacities must be higher than the observations. By extreme value theory, the collection of flow maxima (block maxima) can be appropriately approximated with a generalized extreme value (GEV) distribution. Because of small sample sizes and the presence of censoring, a Bayesian framework is pursued for model fitting and parameter estimation. To lend credence to our proposed methodology, the procedure is applied to real-world traffic stream data collected by the New Hampshire Department of Transportation (NHDOT) at a busy location on Interstate I-93 near Salem, New Hampshire. Data were collected over a period of 11 months and raw data were aggregated into 15-minute intervals. To assess our procedure, and to provide proof of concept, several validation procedures are presented. First, using distinct training and validation subsets of our data, the procedure yields accurate predictions of highway capacity. Next, our procedure is applied to a training set to yield random capacities which are then used to predict breakdown in the validation set. The frequency of these predicted breakdowns is found to be statistically similar to observed breakdowns observed in our validation set. Lastly, after comparing our methodology to other methods of stochastic capacity estimation, we find our procedure to be highly successful.
Źródło:
Archives of Transport; 2018, 48, 4; 61-75
0866-9546
2300-8830
Pojawia się w:
Archives of Transport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modeling of thermal contact through gap with the use of Finite Element Method
Autorzy:
Węgrzyn-Skrzypczak, E.
Skrzypczak, T.
Powiązania:
https://bibliotekanauki.pl/articles/122945.pdf
Data publikacji:
2015
Wydawca:
Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
Tematy:
computational mechanics
thermal contact problem
finite element method
Opis:
In the paper the mathematical and numerical descriptions of the general case of thermal contact between two flat bodies are presented. The numerical model of the problem is based on the Finite Element Method (FEM). Variable width of the contact gap between interacting bodies is considered. The model allows the use of independent spatial discretization of the contacting components, which means that the edges of the finite elements lying on the both sides of the contact gap need not be matched. The algorithm of treatment of the fourth kind boundary condition is described in details.
Źródło:
Journal of Applied Mathematics and Computational Mechanics; 2015, 14, 4; 145-152
2299-9965
Pojawia się w:
Journal of Applied Mathematics and Computational Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review of Lattice Boltzmann Method Applied to Computational Aeroacoustics
Autorzy:
Shao, Weidong
Li, Jun
Powiązania:
https://bibliotekanauki.pl/articles/177111.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
lattice Boltzmann method
computational aeroacoustics
dispersion
dissipation
perfectly matched layers
discontinuous Galerkin method
Opis:
This paper presents the research studies carried out on the application of lattice Boltzmann method (LBM) to computational aeroacoustics (CAA). The Navier-Stokes equation-based solver faces the difficulty of computational efficiency when it has to satisfy the high-order of accuracy and spectral resolution. LBM shows its capabilities in direct and indirect noise computations with superior space-time resolution. The combination of LBM with turbulence models also work very well for practical engineering machinery noise. The hybrid LBM decouples the discretization of physical space from the discretization of moment space, resulting in flexible mesh and adjustable time-marching. Moreover, new solving strategies and acoustic models are developed to further promote the application of LBM to CAA.
Źródło:
Archives of Acoustics; 2019, 44, 2; 215-238
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Numerical simulations of arteries with an adaptive finite element method
Autorzy:
Fuksa, A. K.
Rachowicz, W.
Powiązania:
https://bibliotekanauki.pl/articles/280674.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
computational biomechanics
finite element method
adaptivity
error estimation
finite deformation
Opis:
This paper presents applications of the adaptive FEM in computational biomechanics. The study involves finite deformation of artery walls built of layers of elastic, nearly incompressible (rubber-like) materials. The models are reinforced with nearly inextensible collagen fibres stretched along the directions close to the circumferential direction. A Total Lagrangian technique based on the displacement-pressure formulation is presented. Residual error estimates and finite element mesh adaptation strategies are developed. The procedures are illustrated for solutions of arteries under various load considerations.
Źródło:
Journal of Theoretical and Applied Mechanics; 2014, 52, 4; 917-925
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Internal stresses in PVD coated tool composites
Autorzy:
Śliwa, A.
Mikuła, J.
Gołombek, K.
Kwaśny, W.
Pakuła, D.
Powiązania:
https://bibliotekanauki.pl/articles/355303.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
analysis and modelling
computational materials science
finite element method
stresses
coatings PVD
Opis:
The aim of work is the investigation of the internal stresses in PVD coated metal matrix composites (MMC). Sintered MMC substrate is composed of the matrix with the chemical composition corresponding to the high-speed steel, reinforced with the TiC type hard carbide phase. Functionally graded composition of MMC providing of high ductility characteristic of steel in the core zone as well as high hardness characteristic of cemented carbides in the surface zone. Internal stresses were determined with use of finite element method in ANSYS environment. The reason of undertaking the work is necessity of develop the research of internal stresses, occurring in the coating, as well as in the adhesion zone of coating and substrate, which makes it possible to draw valuable conclusions concerning engineering process of the advisable structure and chemical composition of coatings. The investigations were carried out on cutting tools models containing defined zones differing in chemical composition. Modelled materials were characteristic of chemical composition corresponding to the high-speed steel at the core, reinforced with the TiC type hard carbide phase with the growing fraction of these phases in the outward direction from the core to the surface, additionally coated with (Ti,Al)N or Ti(C.N) functionally graded PVD coatings. Results of determined internal stresses were compared with the results calculated using experimental X-ray sin2ψ method. It was demonstrated, that the presented model meets the initial criteria, which gives ground to the assumption about its utility for determining the stresses in coatings as well as in functionally graded sintered materials. The results of computer simulations correlate with the experimental results.
Źródło:
Archives of Metallurgy and Materials; 2016, 61, 3; 1371-1378
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A novel hybrid iterative method for applied mathematical models with time-efficiency
Autorzy:
Jamali, Khalid
Solangi, Muhammad Anwar
Qureshi, Sania
Powiązania:
https://bibliotekanauki.pl/articles/2202025.pdf
Data publikacji:
2022
Wydawca:
Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
Tematy:
nonlinear equation
computational order
efficiency index
convergence order
Newton’s method
równanie nieliniowe
Opis:
Non-linear phenomena appear in many fields of engineering and science. Research on numerical methods is continually extending with the improvement of the latest computing tools. In today’s computational field, one requires maximum achievement in a minimum amount of time. Therefore, there is a need to modify the Newton-type method to achieve higher-order convergence to solve non-linear equations. While the modified methods are expected to be higher-order convergent, the minor computational information and the maximum time efficiency are also important factors. We propose a three-step hybrid iterative method having a non-linear nature. Per iteration, the method requires three function evaluations and three first-order derivatives. The method is theoretically proven to be tenth-order convergent. The mathematical results of the proposed strategy to solve models from fluid dynamics, electric field, and real gases demonstrated better performance. In light of error analysis, computational productivity, and CPU times, the proposed method’s performance is compared to the famous Newton and a recently proposed tenth-order method.
Źródło:
Journal of Applied Mathematics and Computational Mechanics; 2022, 21, 3; 19--29
2299-9965
Pojawia się w:
Journal of Applied Mathematics and Computational Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pseudospectral approximation compared with control volume formulation and finite differences- some test cases
Autorzy:
Tyliszczak, A.
Bogusławski, A.
Powiązania:
https://bibliotekanauki.pl/articles/1953944.pdf
Data publikacji:
2000
Wydawca:
Politechnika Gdańska
Tematy:
computational fluid dynamics CFD
CFD
spectral methods
pseudospectral method
supersonic flows
driven cavity
Opis:
The paper presents comparison of the pseudospectral method with low-order approximation for two test cases. The first test case is quasi one-dimensional supersonic flow through converging-diverging nozzle for which exact solution exists. The comparison of the error of pseudospectral approximation and upwind finite-differences using Steger-Warming flux splitting method shows high accuracy of the pseudospectral method even for few collocation points. The same conclusion is formulated for the second test case, namely incompressible flow in two-dimensional driven cavity solved by control volume formulation with modified QUICK upwinding scheme and SIMPLEC algorithm for pressure correction. As usually conclusions concerning accuracy of numerical methods are flow case dependent, but the two examples shown give some idea about the accuracy and resolution of spectral approximation versus standard CFD schemes.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2000, 4, 2; 193-202
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Low voltage modular circuit breakers: FEM employment for modelling of arc chambers
Autorzy:
Kolimas, Ł.
Łapczyński, S.
Szulborski, M.
Świetlik, M.
Powiązania:
https://bibliotekanauki.pl/articles/201038.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
miniature circuit breaker
finite element method (FEM)
computational fluid dynamics (CFD)
arc chambers
Opis:
FEM (finite element method) is an essential and powerful numerical method that can explicitly optimize the design process of electrical devices. In this paper, the employment of FEM tools such as SolidWorks, COMSOL and ANSYS is proposed in order to aid electrical apparatuses engineering and modeling – those are arc chambers of modular circuit breakers. Procured models of arc chambers have been undergoing simulations concerning heating, electric potential distribution, electric charge velocity and traverse paths. The data acquired has been juxta-positioned against experimental data procured in the Short-Circuit Laboratory, Warsaw University of Technology. The reflection of the theoretical approach was clearly noted in the experimental results. Mutual areas of the modeled element expressed the same physical properties and robustness errors when tested under specific conditions – faithfully reflecting those which were experimented with. Moreover, the physical phenomena essential for electrical engineering could be determined already at the model stage. This procedure proved highly valuable during designing/engineering work in terms of material economy.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2020, 68, 1; 61-70
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Recent advances in computational chemistry for identification of ligands for biological receptors: interdisciplinary aspects
Autorzy:
Todorov, M.
Powiązania:
https://bibliotekanauki.pl/articles/1715.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
computational chemistry
identification
ligand
biological receptor
nuclear receptor
human health
interdisciplinary aspect
QSAR method
Opis:
Background: Computational (in silico) methods, such as quantitative structure-activity relationships (QSARs) are already well recognized and used in many screening programs related to environmental, industrial and medical chemistry. The main idea of the QSAR is that there is a relationship between molecular structure and ultimate biological effect caused by a chemical compound. In this respect the approach could be used successfully for prediction of various biological endpoints caused by chemical compounds including receptor binding affinity. Aim of the study: In the current study the capabilities for structure-activity modelling incorporated in noncommercial software tool have been employed for investigating the binding effect of xenobiotics toward estrogen and human pregnane X receptor. Material and methods: The analysis was performed by making use of the non-commercial software platform QSAR Toolbox. This system allows application of a set of built-in models for different biological effects, and also allows incorporation of new models for other endpoints. Results: Two models have been applied for predicting the binding effect toward estrogen and human pregnane X receptors of a large number of chemicals collected in a single database of high practical concern. The results show that there are many chemicals which are able to bind the investigated receptors. Since those chemicals are encountered in the environment, they could be considered as potential threat for society. Conclusions: The obtained results could be used as initial step for further experimental testing of those chemicals in order to confirm their potential to harm biological systems in the body.
Źródło:
Medical Science Pulse; 2018, 12, 1
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 47

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