Temat: chronic ulcer - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Role of interleukin-4 in down-regulation of endothelin-1 during gastric ulcer healing: effect of sucralfate
Autorzy:: Slomiany, B.L.
Piotrowski, J.
Slomiany, A.
Powiązania:: https://bibliotekanauki.pl/articles/70539.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: chronic ulcer
gastric ulcer
interleukin 4
sucralfate
ulcer healing
tumour necrosis factor-alpha
gastric mucosa
endothelin-1
caspase-3
apoptosis
rat
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: The “biological chamber” method – use of autologous platelet-rich plasma (PRP) in the treatment of poorly healing lower-leg ulcers of venous origin
Autorzy:: Waniczek, Dariusz
Mikusek, Wojciech
Kamiński, Tomasz
Wesecki, Mariusz
Lorenc, Zbigniew
Cieślik-Bielecka, Agata
Powiązania:: https://bibliotekanauki.pl/articles/1395656.pdf
Data publikacji:: 2015-06-01
Wydawca:: Index Copernicus International
Tematy:: chronic lower-leg venous ulcer
autologous platelet-rich plasma
Opis:: Wound healing is a complex pathophysiological process, in which platelets play a crucial role. Platelet alpha-granules release growth factors to the wound bed; the factors are necessary in the healing process. In chronic wounds, such as poorly healing lower-leg ulcers of venous origin, there is decreased activity of multiple growth factors, so the concept of exogenous delivery of such factors seems a logical strategy. Platelet-rich plasma therapy in patients with lower-leg ulcers of venous origin combined with conventional treatment methods (previously ineffective in these patients) seems, based on our observation, an important adjunct leading to recovery. The aim of the study was to present an original method of autologous platelet-rich plasma application through the creation of a sort of “biological chamber” containing a concentrate of growth factors. Material and methods. The described therapy was implemented in 10 patients, who had been ineffectively treated for more than one year in the outpatient setting. Patients with exacerbation of inflammatory process, signs of wound infection and ankle brachial pressure index < 0.8 were excluded from the study. After the application of platelet-rich plasma, further treatment was continued with the use of moist therapy and compression therapy according to a uniform regimen. Results. Complete healing was achieved within 4-10 weeks from the beginning of the product administration in all patients. Conclusion. The presented method seems technically simple, effective and relatively inexpensive
Źródło:: Polish Journal of Surgery; 2015, 87, 6; 283-289
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki