Temat: chronic respiratory disease - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Nanomedicine - a boon for respiratory disease management
Autorzy:: Balasubramanian, D.
Lavanya, S.J.
Girigoswami, A.
Girigoswami, K.
Powiązania:: https://bibliotekanauki.pl/articles/24200620.pdf
Data publikacji:: 2023
Wydawca:: Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
Tematy:: nanomedicine
asthma
chronic obstructive pulmonary disease
cystic fibrosis
respiratory diseases
nanomedycyna
astma
przewlekła obturacyjna choroba płuc
mukowiscydoza
choroby układu oddechowego
Opis:: Purpose: Respiratory diseases affect the lungs and other parts of the respiratory system. The respiratory disease affects hundreds of millions of humans, and premature death is observed in nearly four million people yearly. The major cause of the increase in this disease is the increased level of air pollution and higher tobacco usage in public places. Design/methodology/approach: We have used the search engines PubMed and Google Scholar for the keywords Respiratory diseases, Nanomaterials, diagnosis, Nanomedicine, and Target drug delivery; recent and relevant articles are selected for reviewing this paper. Findings: Nanomedicine is a recent field of research that deals with monitoring, repairing, theragnosis, and development of human biological systems at the sub-atomic level, where we utilize engineered nanodevices and nanostructures. The conventional therapeutic strategies designed for respiratory diseases have limited solubility and bioavailability. Moreover, the robust effect of the drugs led to adverse side effects due to their high dose requirement. The local delivery of therapeutic Nanoparticles (NPs) or drug-loaded nano vehicles to the lung is a safe technique for managing various respiratory tract-related diseases like chronic obstructive pulmonary diseases, cystic fibrosis, lung cancer, tuberculosis, asthma, and infection. To overcome the difficulties of conventional treatment with antibiotics and anti-inflammatory drugs, nano-enabled drug delivery, nanoformulations of drugs as well as drug nanoencapsulation have been used recently. In this mini-review, we will discuss the importance and application of nanomedicine for diagnosis, treatment and clinical research involved in the different types of respiratory diseases. Practical implications: Nanomedicine provides an alternative delivery of drugs with the help of various nanocarriers, which enhances controlled drug delivery at the pulmonary region and can be used for treating and diagnosing respiratory diseases in vivo and in vitro studies. Further experiments followed by clinical examination are warranted to prove the potential application of nanomedicine in treating respiratory disease. Originality/value: This mini-review will help the readers and budding scientists apply new methods for developing highly efficient drugs with low side effects and improved targeted sites of action.
Źródło:: Archives of Materials Science and Engineering; 2023, 119, 2; 71--85
1897-2764
Pojawia się w:: Archives of Materials Science and Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Comorbidities and clinical outcomes of a lung cancer screening trial participants with chronic obstructive pulmonary disease in three-year follow-up
Autorzy:: Undrunas, Aleksandra
Bąk, Agata
Kasprzyk, Piotr
Dziedzic, Robert
Dziurda, Dominik
Rzyman, Witold
Gierlotka, Marek
Kuziemski, Krzysztof
Powiązania:: https://bibliotekanauki.pl/articles/25714585.pdf
Data publikacji:: 2022-10-03
Wydawca:: Gdański Uniwersytet Medyczny
Tematy:: chronic obstructive pulmonary disease
diagnostic radiology
oncology
lung cancer
respiratory tract
screening
Opis:: Background To improve the effectiveness of lung cancer screening using low-dose computed tomography (LDCT), the presence of smoking-related comorbidities that may significantly affect mortality in this group should be taken into account. Material and methods A questionnaire survey and spirometry tests were conducted in a group of 730 respondents as part of a lung cancer screening study between 2016 and 2018. People diagnosed with COPD underwent a three-year follow-up to assess the incidence of medical events. Results Our study confirmed that cardiovascular diseases (CVDs) were the most common comorbidities in patients who were diagnosed with COPD and participated in LDCT lung cancer screening. Among the CVDs, the most common were arterial hypertension (45.8%) and coronary artery disease (12.5%). Tobacco-related diseases (e.g. CVD, lung cancer, and exacerbations of COPD) were the leading causes of emergency department visits and hospitalizations. The number of visits due to COPD in specialized clinics more than doubled in the observed period. Conclusions Properly planned screening tests allow not only for the detection of the disease for which they were designed but also for the assessment of comorbidities. In patients undergoing lung cancer screening, it is justified to extend the diagnostics to include spirometry.
Źródło:: European Journal of Translational and Clinical Medicine; 2022, 5, 2; 24-30
2657-3148
2657-3156
Pojawia się w:: European Journal of Translational and Clinical Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
Autorzy:: Galiniak, S.
Aebisher, D.
Rachel, M.
Powiązania:: https://bibliotekanauki.pl/articles/2087917.pdf
Data publikacji:: 2020
Wydawca:: Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:: nitric oxide
smoking
respiratory diseases
chronic obstructive pulmonary disease
Opis:: Background: Measurement of fractional exhaled nitric oxide (FeNO) is a useful technique for detection of eosinophilic airway inflammation and assessment of efficiency of corticosteroid treatment in patents with respiratory disease. Generally studies agree that measurement of FeNO is a useful non-invasive biomarker in patients with chronic obstructive pulmonary disease (COPD), however, there are reports that do not confirm such a relationship between FeNO and COPD. Aim of the study: The main objective of this study was to investigate FeNO levels in Polish patients with COPD compared to healthy controls. As a secondary objective, we assessed the influence of smoking on FeNO levels in healthy patients, and patients with COPD. Material and methods: FeNO concentration was measured using an electrochemical analyzer in healthy nonsmokers (n=21), healthy smokers (n=25), and former smokers with COPD (n=30) and smokers with COPD (n=38). General characteristics, hematological variables and serum biochemical parameters were also obtained and analyzed using the Kruskal-Wallis test. Results: FeNO measurement revealed significantly reduced NO levels in healthy smokers compared to healthy non-smokers, former smokers with COPD and smokers with COPD (median [range]: 14 [6–17] vs. 21 [15–29], 25 [15–53], and 19 [11–32] ppb, respectively, p<0.001). Moreover, we found increased FeNO levels in ex-smokers with COPD compared with smokers with COPD (p<0.05). No associations between FeNO and other analyzed parameters were found. Conclusions: Levels of FeNO, measured by with an electrochemical analyzer, were elevated among patients with COPD compared to healthy non-smoking controls. Moreover, our study confirms that smoking results in a reduction in FeNO concentration in both healthy patients and patients with COPD.
Źródło:: Medical Science Pulse; 2020, 14, 2; 36-43
2544-1558
2544-1620
Pojawia się w:: Medical Science Pulse
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Methodologies of inspiratory muscle training techniques in obstructive lung diseases
Metodologie treningu mięśni wdechowych w chorobach obturacyjnych układu oddechowego
Autorzy:: Kaszuba, Marek
Śliwka, Agnieszka
Piliński, Rafał
Nowobilski, Roman
Wloch, Tomasz
Powiązania:: https://bibliotekanauki.pl/articles/1790967.pdf
Data publikacji:: 2019-03-29
Wydawca:: Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
Tematy:: inspiratory muscle training
respiratory muscle training
pulmonary rehabilitation
pulmonary disease
chronic obstructive
asthma
trening mięśni wdechowych
trening mięśni oddechowych
rehabilitacja pulmonologiczna
przewlekła obturacyjna choroba
płuc
astma
Opis:: Background: Inspiratory muscle training (IMT) is a non-pharmacological, non-invasive therapeutic method that can improve the quality of life in patients with obstructive lung diseases. The effectiveness of IMT may depends on the type of the device used in the training and the parameters of the training programme. Objectives: The aim of the review was to present different techniques and protocols of IMT used in patients with obstructive lung diseases. Methods: The MEDLINE and EMBASE were searched to identify the potentially eligible publications from the previous 5 years. The various protocols of IMT used in different studies were analysed and described in detail. Results: A database search identified 333 records, of which 22 were included into the final analysis. All of the finally analysed studies were conducted in patients with chronic obstructive pulmonary disease (COPD). The protocols of IMT used in the studies differed in the type of the device used, the duration of the training programme, the number and the duration of training sessions, the initial load, and the rate at which the load was changed during the training. Conclusions: IMT is used mainly in studies on patients with COPD and not with asthma. There is no one approved training programme for IMT. The most predominant type of IMT is a training with threshold loading. The most frequently used devices for IMT are POWERbreath and Threshold IMT. The protocols of IMT used in the studies are very diverse.
WSTĘP: Trening mięśni oddechowych (IMT) należy do niefarmakologicznych, nieinwazyjnych metod terapeutycznych, które mogą prowadzić do poprawy jakości życia pacjentów z chorobami układu oddechowego. Skuteczność IMT może zależeć od rodzaju urządzenia użytego do treningu oraz parametrów programu treningowego. CELE: Celem przeglądu było przedstawienie różnych technik i protokołów IMT stosowanych u pacjentów z obturacyjnymi chorobami płuc. METODY: W celu zidentyfikowania publikacji z ostatnich 5 lat potencjalnie kwalifikujących się do analizy przeszukano elektroniczne bazy MEDLINE i EMBASE. Szczegółowo przeanalizowano i opisano protokoły IMT stosowane w różnych pracach badawczych. WYNIKI: W efekcie wyszukiwania w bazie danych zidentyfikowano 333 rekordy, z których 23 zostały włączone do ostatecznej analizy. Wszystkie finalnie przeanalizowane badania zrealizowano u pacjentów z przewlekłą obturacyjną chorobą płuc (POChP). Protokoły IMT stosowane w badaniach różniły się rodzajem stosowanego urządzenia, czasem trwania programu treningowego, liczbą i czasem trwania sesji treningowych, początkowym obciążeniem oraz szybkością zmiany obciążenia podczas treningu. WNIOSKI: IMT jest ostatnio stosowany głównie w badaniach nad pacjentami z POChP, a nie z astmą. Nie istnieje jeden zatwierdzony program treningowy dla IMT. Najczęściej stosowanym rodzajem IMT jest trening z obciążeniem progowym. Najbardziej rozpowszechnionymi urządzeniami do IMT są POWERbreath i Threshold IMT. Protokoły IMT wykorzystywane w badaniach naukowych są bardzo zróżnicowane.
Źródło:: Medical Rehabilitation; 2018, 22(4); 49-57
1427-9622
1896-3250
Pojawia się w:: Medical Rehabilitation
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Chronic respiratory symptoms of poultry farmers and model-based estimates of long-term dust exposure
Autorzy:: Guillam, M.T.
Pedrono, G.
Le Bouquin, S.
Huneau, A.
Gaudon, J.
Leborgne, R.
Dewitte, J.D.
Segala, C.
Powiązania:: https://bibliotekanauki.pl/articles/51420.pdf
Data publikacji:: 2013
Wydawca:: Instytut Medycyny Wsi
Tematy:: chronic respiratory disease
poultry farm
farmer
long-term exposure
dust exposure
occupational exposure
respirable dust
task
environment monitoring
chronic bronchitis
bronchitis
human disease
occupational disease
Opis:: Objectives. The airborne contaminant exposure levels experienced by poultry farmers have raised concerns about the possible health hazards associated with them. Thus, a longitudinal project was instituted in France to monitor these exposures in poultry workers and to evaluate the long-term effect on health. Method. Sixty-three workers in two different poultry housing systems were included (33 from floor-based systems and 30 from cage-based systems). Personal dust concentrations (over 2 days) and activity patterns (over 14 days) were collected and then modeled to obtain average long-term estimates. Health data were collected by questionnaire. Results. The mean daily time spent in the cage system was more than 2 hours longer than in the floor system. Two main common tasks accounted for ~70% of this time. Dust concentrations were higher in the floor system than in the cage system. The concentrations for the 14 days of known activity patterns estimated using the statistical model agreed well with the measured values. Several chronic respiratory symptoms were significantly associated with the high levels of long-term exposure estimated by the model. The highest risk was for chronic bronchitis symptoms (>4-fold higher for exposures of 0.1 mg/m3 of respirable dust). Conclusion. The presented modeling strategy can be used to estimate the long-term average personal exposure to respirable dust, and to study the association between dust exposure and chronic respiratory symptoms. This population of workers will be followed-up in subsequent examinations (3 years later) to determine whether the predictive model is valid, and whether long-term dust exposure is related to the incidence of respiratory symptoms and changes in pulmonary functions.
Źródło:: Annals of Agricultural and Environmental Medicine; 2013, 20, 2
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki