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    Tytuł:
    Wpływ stężeń pyłów (PM1, PM2,5, PM10) w środowisku wewnątrz szkoły na wartości wskaźników spirometrycznych u dzieci
    Influence of PM1, PM2.5, PM10 Concentrations in Indoor School Environment on Spirometric Parameters in Schoolchildren
    Autorzy:
    Zwoździak, A.
    Sówka, I.
    Fortuna, M.
    Balińska-Miśkiewicz, W.
    Willak-Janc, E.
    Zwoździak, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1819205.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Koszalińska. Wydawnictwo Uczelniane
    Tematy:
    wskaźniki spirometryczne
    stężenie pyłów
    ambient air pollution
    lung-function
    cardiopulmonary mortality
    particulate matter
    children
    exposure
    association
    particles
    panel
    fine
    Opis:
    The influence of the aerosols particles on the lung function was investigated by the measurements of lung function parameters in children at secondary school located in the centre of city Wroclaw (south – west of Poland). Simultaneous daily indoor and outdoor measurements of PM1, PM2,5, PM10 have been conducted with the use of Harvard cascade impactors (MS&T Area Samplers). In the study 186 children age 13–14 yrs underwent repeated spirometry (Blue Spiro) at the same time of day, 5 times during the winter/spring (heating season) and 5 times in summer/autumn. Exposure to indoor fine particulate matter PM2,5 significantly worseness FEV1 in the lung function of secondary school children (Pearson correlation: median versus indoor PM2,5, r = -0,95; p < 0.05). Correlation of the lung function parameters with other particles PM1, PM10 measured indoor and outdoor were not statistically significant. PM2.5 measured outdoor was also not significantly correlated with lung function parameters. Considerable effort should be made to improve ambient air quality. Especially there is a need to measure and control the fine particulate matter PM2,5 in winter as it has the highest impact on lung function in children.
    Źródło:
    Rocznik Ochrona Środowiska; 2013, Tom 15, cz. 3; 2022-2038
    1506-218X
    Pojawia się w:
    Rocznik Ochrona Środowiska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical, biochemical and genetic risk factors for 30-day and 5-year mortality in 518 adult patients subjected to cardiopulmonary bypass during cardiac surgery - the INFLACOR study
    Autorzy:
    Kowalik, Maciej
    Lango, Romuald
    Siondalski, Piotr
    Chmara, Magdalena
    Brzeziński, Maciej
    Lewandowski, Krzysztof
    Jagielak, Dariusz
    Klapkowski, Andrzej
    Rogowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1038396.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cardiac surgery
    cardiopulmonary bypass
    30-day mortality
    5-year mortality
    ICAM1 rs5498
    ICAM-1
    renal replacement therapy.
    Opis:
    There is increasing evidence that genetic variability influences patients' early morbidity after cardiac surgery performed using cardiopulmonary bypass (CPB). The use of mortality as an outcome measure in cardiac surgical genetic association studies is rare. We publish the 30-day and 5-year survival analyses with focus on pre-, intra-, postoperative variables, biochemical parameters, and genetic variants in the INFLACOR (INFLAmmation in Cardiac OpeRations) cohort. In a prospectively recruited cohort of 518 adult Polish Caucasians, who underwent cardiac surgery in which CPB was used, the clinical data, biochemical parameters, IL-6, soluble ICAM-1, TNFα, soluble E-selectin, and 10 single nucleotide polymorphisms were evaluated for their association with 30-day and 5-year mortality. The 30-day mortality was associated with: pre-operative prothrombin international normalized ratio, intra-operative blood lactate, postoperative serum creatine phosphokinase, and acute kidney injury requiring renal replacement therapy (AKI-RRT) in logistic regression. Factors that determined the 5-year survival included: pre-operative NYHA class, history of peripheral artery disease and severe chronic obstructive pulmonary disease, intra-operative blood transfusion; and postoperative peripheral hypothermia, myocardial infarction, infection, and AKI-RRT in Cox regression. Serum levels of IL-6 and ICAM-1 measured three hours after the operation were associated with 30-day and 5-year mortality, respectively. The ICAM1 rs5498 was associated with 30-day and 5-year survival with borderline significance. Different risk factors determined the early (30-day) and late (5-year) survival after adult cardiac surgery in which cardiopulmonary bypass was used. Future genetic association studies in cardiac surgical patients should account for the identified chronic and perioperative risk factors.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 2; 241-250
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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