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Wyszukujesz frazę "brain-skull" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Mechanical properties of the brain–skull interface
Autorzy:
Mazumder, M. M. G.
Bunt, S.
Mostayed, M.
Joldes, G.
Day, R.
Hart, R.
Wittek, A.
Powiązania:
https://bibliotekanauki.pl/articles/307196.pdf
Data publikacji:
2013
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
biomechanics
brain-skull
interface
mechanical properties
FEM
biomechanika
metoda elementów skończonych
właściwości mechaniczne
Opis:
Knowledge of the mechanical properties of the brain-skull interface is important for surgery simulation and injury biomechanics. These properties are known only to a limited extent. In this study we conducted in situ indentation of the sheep brain, and proposed to derive the macroscopic mechanical properties of the brain–skull interface from the results of these experiments. To the best of our knowledge, this is the first ever analysis of this kind. When conducting in situ indentation of the brain, the reaction force on the indentor was measured. After the indentation, a cylindrical sample of the brain tissue was extracted and subjected to uniaxial compression test. A model of the brain indentation experiment was built in the Finite Element (FE) solver ABAQUSTM. In the model, the mechanical properties of the brain tissue were assigned as obtained from the uniaxial compression test and the brain-skull interface was modeled as linear springs. The interface stiffness (defined as sum of stiffnesses of the springs divided by the interface area) was varied to obtain good agreement between the calculated and experimentally measured indentor force–displacement relationship. Such agreement was found to occur for the brain-skull interface stiffness of 11.45 (mm [to -1]/ Nmm [to 2].). This allowed identification of the overall mechanical properties of the brain–skull interface.
Źródło:
Acta of Bioengineering and Biomechanics; 2013, 15, 2; 3-11
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A long clinical course with late distant metastases from follicular thyroid carcinoma
Autorzy:
Erok, Berrin
Harmancı, Kemal
Aksaray, Ferdi
Unlu, Nazmi Uğur
Aydın, Seckin
Powiązania:
https://bibliotekanauki.pl/articles/2040497.pdf
Data publikacji:
2021-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
follicular thyroid carcinoma
brain metastasis
skull metastasis
Opis:
Introduction. Follicular thyroid carcinoma (FTC) accounts for 10-20% of the differentiated thyroid carcinomas (DTCs), and it is the second most common thyroid malignancy after papillary thyroid carcinoma (PTC). FTC is typically more common in women and in older age group than PTC. Unlike PTC, FTC metastases late to the lymph nodes, with only up to 10-20% of the patients having nodal metastases at the time of diagnosis.On the other hand, distant metastasis via hematogenous spread is more likely in patients with FTC due to the invasion of blood vessels. Prognosis depends on the extent of the distant metastasis which drop 10-year survival significantly. Aim. Although DTCs have usually favorable prognosis, metastatic disease in these patients has a long clinical course. Cranial imaging in these patients should be performed during the follow-up after the treatment of FTC with thyroidectomy and RAI. Description of the case. We report a case of late onset but catastrophic hematogenous distant metastases beginning 8 years after the diagnosis & treatment of FTC and becommimg widespread during the following 10 years with a long clinical course in a 60 year old female patient. Conclusion. In the RAI refractory metastatic lesions SRS and surgical resections should be conserned as the first management approach to improve survival.
Źródło:
European Journal of Clinical and Experimental Medicine; 2021, 4; 347-351
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
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