- Tytuł:
- Sulodexide: A new model for treating the early stages of diabetic retinopathy
- Autorzy:
- Wylęgała, Adam
- Powiązania:
- https://bibliotekanauki.pl/articles/51789546.pdf
- Data publikacji:
- 2023-12-04
- Wydawca:
- Medical Education
- Tematy:
-
glycocalyx
hard exusdates
sulodexide
diabetic retinopathy
blood vessel protection - Opis:
- Glycocalyx is the surface layer of endothelial cells, it lines the blood vessels and provides a cellular barrier against damage. Sulodexide has a protective effect on the glycocalyx and allows it to be rebuilt, and has anti-inflammatory, antioxidant, anticoagulant, and lipid profile-enhancing properties. Diabetic retinopathy damages the glycocalyx and vascular endothelium in the retina. Sulodexide rebuilds the glycocalyx and increases the integrity of the blood-retinal barrier, thereby protecting the retinal vasculature retina from hyperglycemia-induced damage. Clinical studies have confirmed that in non-proliferative diabetic retinopathy, sulodexide improves visual acuity, reduces microaneurysms and hard exudates. Further in a study evaluating recurrent retinal vein thrombosis, sulodexide reduced the recurrence rate. Sulodexide is a safe and well-tolerated drug and may play an important role in the treatment of diabetic retinopathy, both in reducing symptoms and improving visual function.
- Źródło:
-
OphthaTherapy; 2023, 10, 4; 269-276
2353-7175
2543-9987 - Pojawia się w:
- OphthaTherapy
- Dostawca treści:
- Biblioteka Nauki
Artykuł