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Wyszukujesz frazę "bioactive composite" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Bioactivity of PLGA-gel-derived bioglass composites
Autorzy:
Łączka, M.
Maślanka, E.
Pawlik, J.
Dziadek, M.
Zagrajczuk, B.
Cholewa-Kowalska, K.
Powiązania:
https://bibliotekanauki.pl/articles/93122.pdf
Data publikacji:
2018
Wydawca:
Państwowa Wyższa Szkoła Zawodowa w Tarnowie
Tematy:
polymer-ceramic composite
bioactive property
kompozyt polimerowo-ceramiczny
właściwość bioaktywna
Opis:
A series of PLGA (poly L-lactide-co-glycolide) based composites modified with gel-derived glasses in the form of foils were obtained by solvent casting procedure. As a modifier, glass particles with different chemical compositions from the CaO–SiO2, CaO–P2O5–SiO2,and Al2O3–SiO2 systems were used. All glasses were synthesized by the sol-gel process. Evaluation of bioactive properties of obtained composites was made on the basis of surface changes occurring during contact with simulated body fluid. The changes of Ca, P and Si ions concentration in SBF after incubation of composites were also measured. The result showed that all composites with bioglasses (CaO–SiO2, CaO–P2O5–SiO2) exhibit formation of calcium phosphates layer after SBF test, however, kinetics of Ca, Si ion release and P uptake from SBF was dependent on bioglass chemical composition. The higher solubility, as well as faster consumption of phosphorus from SBF, was observed for materials from CaO–SiO2 (T1/PLGA, S1/PLGA) compared to composites with respective bioglass particles from the CaO–P2O5–SiO2(T2/PLGA, S2/PLGA). Our results showed that rate of Si and Ca release from the gel-derived glasses and P uptake from SBF are dependent on both: the concentration of respective ions in the materials and the presence of phosphates in their structure. For materials modified with gel-derived glasses from Al2O3–SiO2 system no significant surface changes during contact with SBF were observed, and it seems that their behavior in physiological solution indicate that they are bio-inert materials.
Źródło:
Science, Technology and Innovation; 2018, 3, 2; 27-34
2544-9125
Pojawia się w:
Science, Technology and Innovation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Preparation and preliminary in vivo studies of resorbable polymer modified with allogenic bone chips for guided bone regeneration and orthopedic implants
Autorzy:
Szaraniec, Barbara
Szponder, Tomasz
Gryń, Karol
Ambroziak, Maciej
Gut, Grzegorz
Koperski, Łukasz
Chłopek, Jan
Powiązania:
https://bibliotekanauki.pl/articles/2058395.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
bioactive composite
resorbable polymers
polylactide
GBR - guided bone regeneration
bone graft
BMP - bone morphogenetic proteins
osteofixation devices
kompozyty
bioaktywność
kości
regeneracja
Opis:
Composites made of resorbable polylactide modified with bone powder are part of the current search for implantable materials endowed with advantageous biomechanical functions, which make them suitable for orthopedics and traumatology applications. The bone additive containing active bone morphogenetic proteins (BMPs) and calcium phosphates introduced into the polymer matrix is to grant the implant with a biological activity. Subsequently, the resorbable matrix should get replaced with bone tissue. In order to avoid losing the osteoinductive properties of the designed material, it should be processed at low temperatures via physicochemical methods. This paper is devoted to the preparation and optimization of the composite production method suitable for biodegradable polymers and morphogenetic proteins along with the assessment of biocompatibility and biological properties of obtained materials. The tape-casting method was successfully applied. Resorbable polymer (medical poly-L-lactide, Purasorb PL38 by Purac) with 15 wt% of human bone powder (from tissue bank) were used to fabricate PLA-CP/BMPs composite implants. They were tested in in vivo studies that were performed in rabbit bone tissues. The results show a high biocompatibility of the material and good osteointegration with bone tissue.
Źródło:
Engineering of Biomaterials; 2021, 24, 162; 13--19
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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