- Tytuł:
- The effect of hydrazine derivatives of 3-formylchromones on angiogenic basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma cell line WM-115
- Autorzy:
-
Łazarenkow, Andrzej
Michalska, Marta
Mirowski, Marek
Słomiak, Krzysztof
Nawrot-Modranka, Jolanta - Powiązania:
- https://bibliotekanauki.pl/articles/1038629.pdf
- Data publikacji:
- 2017
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
angiogenesis
basic fibroblast growth factor
fibroblast growth factor receptor 1
human melanoma
hydrazone derivatives of benzo-γ-pyrones - Opis:
- The hydrazine derivatives of benzopyrones remain an unexplored group of chemical compounds. This preliminary study investigates the influence of A-5, CH-3 and K-2 derivatives at concentrations of 1, 10, 100 nM and 1 μM on selected biochemical factors of a melanoma cell line WM-115, with regard to their potential angiogenic properties. The studied compounds were found to influence cell proliferation, as well as total protein, bFGF and FGFR1 concentration.
- Źródło:
-
Acta Biochimica Polonica; 2017, 64, 3; 585-590
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł