Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "augmentation" wg kryterium: Temat


Tytuł:
AI empowered diagnosis of pemphigus: a machine learning approach for automated skin lesion detection
Diagnostyka pęcherzycy z wykorzystaniem sztucznej inteligencji: podejście oparte na uczeniu maszynowym do automatycznego wykrywania zmian skórnych
Autorzy:
Ahmed, Mamun
Islam, Salma Binta
Alif, Aftab Uddin
Islam, Mirajul
Saima, Sabrina Motin
Powiązania:
https://bibliotekanauki.pl/articles/27315458.pdf
Data publikacji:
2023
Wydawca:
Politechnika Lubelska. Wydawnictwo Politechniki Lubelskiej
Tematy:
pemphigus
blister
augmentation
CNN
pęcherzyca
pęcherze
augmentacja
Opis:
Pemphigus is a skin disease that can cause a serious damage to human skin. Pemphigus can result in other issues including painful patches and infected blisters, which can result in sepsis, weight loss, and starvation, all of which can be life-threatening, tooth decay and gum disease. Early prediction of Pemphigus may save us from fatal disease. Machine learning has the potential to offer a highly efficient approach for decision-making and precise forecasting. The healthcare sector is experiencing remarkable advancements through the utilization of machine learning techniques. Therefore, to identify Pemphigus using images, we suggested machine learning-based techniques. This proposed system uses a large dataset collected from various web sources to detect Pemphigus. Augmentation has been applied on our dataset using techniques such as zoom, flip, brightness, distortion, magnitude, height, width to enhance the breadth and variety of the dataset and improve model’s performance. Five popular machine learning algorithms has been employed to train and evaluate model, these are K-Nearest Neighbor (referred to as KNN), Decision Tree (DT), Logistic Regression (LR), Random Forest (RF), and Convolutional Neural Network (CNN). Our outcome indicate that the CNN based model outperformed the other algorithms by achieving accuracy of 93% whereas LR, KNN, RF and DT achieved accuracies of 78%, 70%, 85% and 75% respectively.
Pęcherzyca to choroba skóry, która może powodować poważne uszkodzenia ludzkiej skóry. Pęcherzyca może powodować inne problemy, w tym bolesne plamy i zakażone pęcherze, które mogą skutkować sepsą, utratą masy ciała i łaknienia, co może zagrażać życiu, próchnicą zębów i chorób dziąseł. Wczesne wykrycie pęcherzycy może uchronić przed śmiertelną chorobą. Uczenie maszynowe może zaoferować wysoce efektywne podejście do podejmowania decyzji i precyzyjnego prognozowania. Sektor opieki zdrowotnej doświadcza niezwykłych postępów dzięki wykorzystaniu technik uczenia maszynowego. Dlatego do identyfikacji pęcherzycy za pomocą obrazów zaproponowano techniki oparte na uczeniu maszynowym. Proponowany system wykorzystuje duży zbiór danych zebranych z różnych źródeł internetowych do wykrywania pęcherzycy. W zbiorze danych zastosowano augmentację przy użyciu technik takich jak powiększanie, odwracanie, zmiana jasności, zniekształcenie, zmiana wielkości, wysokość i szerokości, aby zwiększyć zakres i różnorodność zbioru danych oraz poprawić wydajność modelu. Do uczenia i oceny modelu wykorzystano pięć popularnych algorytmów uczenia maszynowego, są to: K-Nearest Neighbor (określany jako KNN), drzewo decyzyjne (DT), regresja logistyczna (LR), las losowy (RF) i konwolucyjną sieć neuronowa (CNN). Uzyskane wyniki wskazują, że model oparty na CNN był lepszy od innych algorytmów, osiągając dokładność na poziomie 93%, podczas gdy LR, KNN, RF i DT osiągnęły dokładność odpowiednio 78%, 70%, 85% i 75%.
Źródło:
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska; 2023, 13, 4; 21--26
2083-0157
2391-6761
Pojawia się w:
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
GNSS for an Aviation
Autorzy:
Grzegorzewski, M.
Cwiklak, J.
Jafernik, H.
Fellner, A.
Powiązania:
https://bibliotekanauki.pl/articles/117124.pdf
Data publikacji:
2008
Wydawca:
Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
Tematy:
Global Navigation Satellite System (GNSS)
Air Navigation
Aviation, Global Positioning System (GPS)
Aircraft-Based Augmentation System (ABAS)
satellite based augmentation system (SBAS)
Ground-Based Augmentation System (GBAS)
EGNOS
Opis:
In Polish aviation on-board GPS units are used for enroute procedures mainly. The use of GNSS for approach and landing procedures requires overcoming a lot of obstructions, including both organizational and technical ones. The paper presents information connecting with GNSS implementation in aviation.
Źródło:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2008, 2, 4; 345-350
2083-6473
2083-6481
Pojawia się w:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Arterial stiffness can predict cardiorespiratory fitness in type 2 diabetic patients?
Autorzy:
Italiano Monteiro, Clara
Polaquini Simões, Rodrigo
Domingues Heubel, Alessandro
Donisete da Silva, Claudio
Ricci, Paula Angélica
Petronilho, Ariane
Borghi-Silva, Audrey
Gonçalves Mendes, Renata
Powiązania:
https://bibliotekanauki.pl/articles/2049182.pdf
Data publikacji:
2022-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
augmentation index
cardiorespiratory fitness
type 2 diabetes
Opis:
Introduction and aim. Arterial stiffness (AS) has been associated with reduced cardiorespiratory fitness (CRF). The aim of this study was to verify if there is a relationship between augmentations index (AIx), as an index for AS assessment, and CRF in individuals with type 2 Diabetes Mellitus (T2DM). Material and methods. Observational cross-sectional study including 32 individuals diagnosed with T2DM who performed two evaluations: 1. Arterial stiffness assessment using SphygmoCor and 2. CRF throughout a cardiopulmonary exercise test on a treadmill ergometer. Oxycon Mobile® device was used to obtain oxygen uptake consumption at peak (V˙O2peak); oxygen uptake efficiency slope (OUES) determined by linear regression in reason of the logarithmic transformation of the ventilation and V˙O2 obtained every minute of exercise test. Statistical analysis comprised Pearson’s Correlation and linear regression analysis performed in SigmaPlot. Results. There was a significant correlation between AS and CRF: AIx and OUES; AIx@75 and; OUES. In linear regression, AIx was determinant for V˙O2peak and OUES – AIx and; AIx@75 and V˙O2peak. Conclusion. AS was associated with CRF in individuals with T2DM. These results contribute to the body of evidence linking arterial functional properties to CRF and suggests greater attention for this important index.
Źródło:
European Journal of Clinical and Experimental Medicine; 2022, 1; 28-35
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Music as Water: The Functions of Music from a Utilitarian Perspective
Autorzy:
Maloney, Liam
Powiązania:
https://bibliotekanauki.pl/articles/632595.pdf
Data publikacji:
2017
Wydawca:
Projekt Avant
Tematy:
augmentation
functions
goal
listeningof music
regulation
resource
utilitarian
Opis:
The rapid increase of technologically enhanced listening platforms gives listeners access to music with ever-increasing ease and ubiquity, giving rise to the suggestion that we should now conceptualize music as a resource similar to water; something that is utilized to achieve everyday goals. This paper proposes that music is a utilitarian resource employed by listeners to augment cognitive, emotional, behavioral, and physiological aspects of the self. To better explore these notions this paper examines the potential role of the “functions of music,” first espoused by Alan P. Merriam in 1964. Merriam suggested music has a situational use and an underlying function (music’s ability to alter the self through listening). The research presented here asserts that listeners interact with specific musical materials to achieve or orientate themselves towards contextually-rooted goals. Reinforcing Tia DeNora’s suggestion that music is a “technology of the self” this research presents the results of a 41 publication meta-analysis exploring the possible functions of music. The resultant Aggregate Thematic Functions Framework (ATF framework) identifies 45 possible utilitarian functions of music, spread across five domains of action. The framework also proposes a meta-domain and an emotional sub-domain
Źródło:
Avant; 2017, 8
2082-6710
Pojawia się w:
Avant
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mixup (sample pairing) can improve the performance of deep segmentation networks
Autorzy:
Isaksson, Lars J.
Summers, Paul
Raimondi, Sara
Gandini, Sara
Bhalerao, Abhir
Marvaso, Giulia
Petralia, Giuseppe
Pepa, Matteo
Jereczek-Fossa, Barbara A.
Powiązania:
https://bibliotekanauki.pl/articles/2147117.pdf
Data publikacji:
2022
Wydawca:
Społeczna Akademia Nauk w Łodzi. Polskie Towarzystwo Sieci Neuronowych
Tematy:
magnetic resonance imaging
segmentation
prostate
data augmentation
mixup
Opis:
Researchers address the generalization problem of deep image processing networks mainly through extensive use of data augmentation techniques such as random flips, rotations, and deformations. A data augmentation technique called mixup, which constructs virtual training samples from convex combinations of inputs, was recently proposed for deep classification networks. The algorithm contributed to increased performance on classification in a variety of datasets, but so far has not been evaluated for image segmentation tasks. In this paper, we tested whether the mixup algorithm can improve the generalization performance of deep segmentation networks for medical image data. We trained a standard U-net architecture to segment the prostate in 100 T2-weighted 3D magnetic resonance images from prostate cancer patients, and compared the results with and without mixup in terms of Dice similarity coefficient and mean surface distance from a reference segmentation made by an experienced radiologist. Our results suggest that mixup offers a statistically significant boost in performance compared to non-mixup training, leading to up to 1.9% increase in Dice and a 10.9% decrease in surface distance. The mixup algorithm may thus offer an important aid for medical image segmentation applications, which are typically limited by severe data scarcity.
Źródło:
Journal of Artificial Intelligence and Soft Computing Research; 2022, 12, 1; 29--39
2083-2567
2449-6499
Pojawia się w:
Journal of Artificial Intelligence and Soft Computing Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Psychological Considerations of Body Image and Self-esteem as Correlates of Augmentation Mammoplasty and Breast Cancer in Women
Autorzy:
Schlebusch, L.
van Oers, H.
Powiązania:
https://bibliotekanauki.pl/articles/1065393.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Body image
augmentation mammoplasty
breast cancer
self-esteem
stress
Opis:
Female breasts have been admired for a variety of reasons throughout the ages. This can influence a preoccupation with breast size. As a result, augmentation mammoplasty (AM) has become a sought-after elective cosmetic procedure, especially in western culture. Research has confirmed the psychological benefits of AM, but it has also shown that some women with a self-perceived inadequate breast size who request AM can present with psychological problems. Likewise, authorities agree that the diagnosis of breast cancer which remains one of the most frequently diagnosed cancers among women worldwide, can have an adverse effect on women psychologically, and that the number of patients who live with the psychological sequelae of both the disease and its treatment continue to rise. Several factors relate to psychological distress in women coping with these issues. In particular, self-esteem and body image-related problems faced by women can add a burden to their psychological well-being. This article reviews some of these issues and psychological treatment options to enhance women’s adjustment in this regard.
Źródło:
World Scientific News; 2019, 132; 52-64
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Radiological changes in maxillary sinus morphology after lateral sinus floor augmentation
Autorzy:
Shpachynskyi, Oleksandr
Didkovskij, Viacheslav
Kopchak, Andrii
Powiązania:
https://bibliotekanauki.pl/articles/1397272.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
computed tomography
implantation
lateral sinus floor augmentation
membrane thickness
Opis:
Background: Restoration of the masticatory function in patients with edentulous posterior maxilla is often challenging due to the severe atrophy of the alveolar ridges and proximity of the maxillary sinus, resulting in insufficient bone quantity for implant-supported dentures. Aim: The purpose of this study was to analyze the changes in Schneiderian membrane thickness after lateral sinus floor augmentation (LSFA) using cone beam computed tomography (CBCT). Material and methods: WLSFA procedures using different bone grafting materials were performed in 87 patients, operated on in two clinical institutions from 2016 to 2018. CBCT examination was performed in all patients before the LSFA procedure, at 1 month after surgery, and after 6 months, before implant placement or loading. Results: Minor r adiological changes in mucous membrane morphology were observed preoperatively in 17.1% of patients. Postoperative CBCT in the early postsurgical period demonstrated that the number of intact non-specific sinuses decreased significantly, i.e. from 86.7% to 26.7%. The number of cases with local hypertrophia of the mucous membrane increased from 20.3% to 26.7%. Mucosal thickening was observed in 41.7% vs 7.5%. The number of intact sinuses increased to 57.8%. The number of cases with local membrane hypertrophia also increased – to 37.4%. The number of cases with mucosal thickening or fluid accumulation decreased significantly to 11.8 and 5.3% respectively. In 2 cases the development of chronic sinusitis required secondary surgeries. Conclusion: The present retrospective study revealed that minor radiological changes in the morphology of the maxillary sinus mucosa were observed preoperatively in 17.1% of patients who underwent LSFA procedures. In the early and late postoperative period their frequency increased to 68.5% and 47.1%, respectively. However, the clinical signs of sinusitis developed only in 19.26% of patients. No significant correlations were found between the frequency and severity of postoperative radiological changes and residual bone height, sinus anatomy, initial state of the mucous membrane and type of the grafting material.
Źródło:
Polish Journal of Otolaryngology; 2021, 75, 2; 34-41
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Defect Detection Using Deep Learning-Based YOLOv3 in Cross-Sectional Image of Additive Manufacturing
Autorzy:
Choi, Byungjoo
Choi, Yongjun
Lee, Moon-Gu
Kim, Jung-Sub
Lee, Sang-Won
Jeon, Yongho
Powiązania:
https://bibliotekanauki.pl/articles/2048889.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
additive manufacturing
deposition defect
data augmentation
YOLOv3
object detection
Opis:
Deposition defects like porosity, crack and lack of fusion in additive manufacturing process is a major obstacle to commercialization of the process. Thus, metallurgical microscopy analysis has been mainly conducted to optimize process conditions by detecting and investigating the defects. However, these defect detection methods indicate a deviation from the operator’s experience. In this study, artificial intelligence based YOLOv3 of object detection algorithm was applied to avoid the human dependency. The algorithm aims to automatically find and label the defects. To enable the aim, 80 training images and 20 verification images were prepared, and they were amplified into 640 training images and 160 verification images using augmentation algorithm of rotation, movement and scale down, randomly. To evaluate the performance of the algorithm, total loss was derived as the sum of localization loss, confidence loss, and classification loss. In the training process, the total loss was 8.672 for the initial 100 sample images. However, the total loss was reduced to 5.841 after training with additional 800 images. For the verification of the proposed method, new defect images were input and then the mean Average Precision (mAP) in terms of precision and recall was 0.3795. Therefore, the detection performance with high accuracy can be applied to industry for avoiding human errors.
Źródło:
Archives of Metallurgy and Materials; 2021, 66, 4; 1037-1041
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Office-based vocal fold augmentation with calcium hydroxylapatite: long-term results
Autorzy:
Sielska-Badurek, Ewelina
Sobol, Maria
Jędra, Katarzyna
Rzepakowska, Anna
Osuch-Wójcikiewicz, Ewa
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1398487.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
vocal fold augmentation
injection laryngoplasty
Calcium hydroxylapatyte
long-term results
Opis:
Aim: We assessed long-term outcomes of vocal fold augmentation with calcium hydroxylapatyte performed under local anesthesia. Material and methods: We enrolled 17 patients with glottic insuf ficiency due to unilateral laryngeal paralysis or insuf ficiency of internal laryngeal muscles (10 women, 17 men; mean age, 57.6±17.7 years; median age, 61 years; age range, 32-83 years). All patients underwent laryngeal augmentation under local anesthesia, through the oral cavity, with calcium hydroxylapatite (Radiesse) injected laterally to the vocal folds, unilaterally or bilaterally. We assessed voice quality before laryngeal augmentation and at 3 and 12 months. To that end, we performed videolaryngostroboscopy, perceptual assessment of voice, acoustic analyses, and aerodynamic assessments; moreover, participants completed the Voice-Related Quality of Life (VRQoL) questionnaire. Results: Af ter 3 months, we observed a statistically significant improvement on the perceptual assessment of voice with regard to the G and A parameters, and good outcomes were also observed at 12 months. On the acoustic analyses, MDVP_Jitt, MDVP_Shim, and MDVP_NHR improved to 2.5, 5, and 0.1, respectively, at 3 months, and to 1.9, 3.6, and 0.1, respectively, at 12 months. MPTa was prolonged to 12.2s and 11.9s at 3 and 12 months, respectively. Voice intensity improved from 67dB(A) before augmentation to 68dB(A) and 71dB(A) at 3 and 12 months, respectively. VRQoL scores improved to 19.5 and 20 at 3 and 12 months, respectively. Discussion: Laryngeal augmentation with calcium hydroxylapatite performed under local anesthesia is associated with good long-term outcomes.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 5; 5-11
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
O augmentatywach w języku łowieckim
Augmentatives in a hunting lexis
Autorzy:
Malczewska, Beata
Powiązania:
https://bibliotekanauki.pl/articles/2109921.pdf
Data publikacji:
2018-12-30
Wydawca:
Uniwersytet w Białymstoku. Wydawnictwo Uniwersytetu w Białymstoku
Tematy:
LSPs
Hunting technolect
word-formation
affectively marked derivation
affixes
augmentation
Opis:
The attempt is made towards compiling and classifying derivatives formed on the basis of nouns, adjectives and verbs according to morphological criteria. Additionally, the derived units subject to analysis are required to contain augmentative, both augmentative and pejorative, as well as ironical and downgrading formatives. The analysis is conducted with the aid of data drawn from interviews and short narratives delivered by hunters (both web-based and available in paper form). Handbooks and dictionaries of hunting lexis and practice were precious tools accordingly. Polish language is demonstrated to boast a large number of modifying derivatives that have an expressive value. Not only is this specialized technical lexis used to convey information in straightforward communicative circumstances. Above all, its significance lies in enabling users to share experience, exchange opinions and get rid of emotions. In point of fact, both individual and collectively performed acts of hunting are emotion-laden. That is why, aside from features inherent in every kind of specialized code (economy, precision and highly routinized manners of encoding), a bundle of peculiar features are found in hunting lexis: a significant degree of subjectivity that becomes most obvious in an extensive use made of affectively marked derivation.
Źródło:
Białostockie Archiwum Językowe; 2018, 18; 163-180
1641-6961
Pojawia się w:
Białostockie Archiwum Językowe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modeling of Ionospheric Delay for SBAS Using Spherical Harmonics Functions
Autorzy:
Han, D.
Yun, H.
Kee, C.
Powiązania:
https://bibliotekanauki.pl/articles/116620.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
Tematy:
Consequences of Delays
Ionospheric Delay
satellite based augmentation system (SBAS)
Opis:
In SBAS (satellite‐based augmentation system), it is important to estimate ionospheric delay accurately to guarantee userʹs accuracy and integrity. Grid based ionospheric models are generally used to estimate ionospheric delay for SBAS. In grid based model, SBAS broadcasts vertical ionospheric delays at the grid point, and users get their ionospheric delay by interpolating those values. Ionospheric model based on spherical harmonics function is another method to estimate ionospheric delay. This is a function based approach and spherical harmonics function is a 2‐D fourier series, containing the product of latitude dependent associated Legendre functions and the sum of the longitude dependent sine and cosine terms. Using ionospheric delay measurements, coefficients for each spherical harmonics functions are estimated. If these coefficients are known, user can reconstruct ionospheric delay. In this paper, we consider the spherical harmonics based model and propose a ionospheric delay estimation strategy for SBAS that can be used to mitigate ionospheric delay estimation error, especially in storm condition. First, coefficients are estimated under initial order and degree. Then residual errors for each measurement are modeled by higher order and degree terms, then coefficients for these terms are estimated. Because SBAS message capacity is limited, in normal condition, initial order terms are only used to estimate ionospheric delay. If ionospheric storm is detected and there is need to mitigate the error, higher order terms are also used and error can be decreased. To compare the accuracy of spherical harmonics based model with grid based model, some post‐processing test results are presented. Raw observation data is obtained from RINEX format and the root mean square(RMS) and max value of residual errors are presented.
Źródło:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2013, 7, 2; 205-209
2083-6473
2083-6481
Pojawia się w:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Numerical study of car radiator using dimple roughness and nanofluid
Autorzy:
Thapa, Robin Kumar
Bisht, Vijay Singh
Bhandari, Prabhakar
Rawat, Kamal Singh
Powiązania:
https://bibliotekanauki.pl/articles/2134933.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
heat transfer
augmentation
nanofluid
pumping power
car radiator
artificial roughness
Opis:
Thermal augmentation in flat tube of car radiator using different nanofluids has been performed more often, but use of artificial roughness has been seldom done. Artificial roughness in the form of dimple is used in the present research work. Present study shows the impact of dimple shaped roughness and nanofluid (Al2O3/pure water) on the performance of car radiator. The pitch of dimples is kept at 15 mm (constant) for all the studies performed. The Reynolds number of the flow is selected in the turbulent regime ranging from 9350 to 23 000 and the concentration of the nanofluid is taken in the range of 0.1–1%. It has been found that the heat transfer rate has improved significantly in dimpled radiator tube on the expense of pumping power. Furthermore, the heat transfer rate also increases with increase in nanoparticle concentration from 0.1% to 1.0%. The highest heat transfer enhancement of 79% is observed at Reynolds number 9350, while least enhancement of 18% is observed for Reynolds number of 23 000.
Źródło:
Archives of Thermodynamics; 2022, 43, 3; 125--140
1231-0956
2083-6023
Pojawia się w:
Archives of Thermodynamics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zmiana nasilenia objawów pozytywnych, negatywnych oraz psychopatologii ogólnej (PANSS) u chorych na schizofrenię po 6 tygodniach augmentacji terapii lekami przeciwpsychotycznymi – glicyną lub donepezilem
Change of severity of positive, negative symptoms and general psychopathology (PANSS) in schizophrenics after 6 weeks augmentation of antipsychotics therapy with glicyne or donepezil
Autorzy:
Rabe-Jabłońska, Jolanta
Strzelecki, Dominik
Powiązania:
https://bibliotekanauki.pl/articles/945670.pdf
Data publikacji:
2005
Wydawca:
Medical Communications
Tematy:
antipsychotics therapy
augmentacja
augmentation
donepezil
glicyna
glycine
leczenie przeciwpsychotyczne
schizofrenia
schizophrenia
Opis:
In aetiopathogenesis of schizophrenia the key role is played by dopaminergic, but also serotoninergic, glutamatergic systems as well as cholinergic neurons. Donepezil is a mixed inhibitor of acetylcholinesterase, selectively inhibiting acetylcholinesterase. A review of the studies, in which donepezil was used for augmentation of antipsychotic treatment does not provide explicit information on the effects of such procedures within a change of scores on PANSS. Pursuant to the assumptions of hypoglutamatergic hypothesis of schizophrenia, the transmission was stimulated within this system. To its stimulation through NMDA receptor among others glycine was used, i.e. prevalent amino acid of the simplest structure, the basic transmitter of glycinergic neurons counted among class I – neurotransmitters, additionally functioning as a coagonist and modulator, also within the glutamatergic system. In 2005 a meta-analysis of studies appeared, from which it results that glycine and D-serine significantly decrease the severity of negative symptoms. The study was aimed at establishing whether or not adjunctive glycine or donepezil applied for 6 weeks with antipsychotic treatment statistically significantly affect a change in the severity of positive symptoms, negative symptoms, general psychopathology in patients at a stable period of the disease. Subjected to the study was a group of 62 patients aged 18-55 years, suffering from paranoidal schizophrenia (DSM-IV) at the mental condition stabilised for at least half a year, without a change in the type and dose of antipsychotic drug at that time. The following methods were used: 1) confirmation of stabilisation of the mental condition and stable pharmacotherapy for the required period according to analysis of medical documentation, interview and evaluation of the current status; 2) augmentation of the hitherto applied antipsychotic treatment by adding donepezil or glycine and 3) evaluation of the severity of negative symptoms, positive symptoms and general psychopathology (PANSS) before and after 6 week augmentation by donepezil or glycine and occurrence of adverse symptoms. Results: Statistically significant differences were obtained after 6 weeks in a group treated with antipsychotic drugs and glycine (primarily within negative symptoms and general psychopathology, less within positive symptoms), whereas in the group additionally treated with donepezil no such differences were found.
W etiopatogenezie schizofrenii kluczową rolę odgrywa układ dopaminergiczny, ale swój udział mają także układ serotoninergiczny i glutaminianergiczny oraz neurony cholinergiczne. Donepezil jest mieszanym inhibitorem acetylocholinesterazy selektywnie hamującym raczej acetylocholinesterazę. Przegląd badań, w których do augmentacji leczenia przeciwpsychotycznego stosowano donepezil, nie dostarcza jasnych informacji na temat efektów takiego postępowania w zakresie zmiany punktacji w podskalach PANSS. Zgodnie z założeniami hipoglutaminianergicznej hipotezy schizofrenii stymulowano transmisję w obrębie tego układu. Do jego pobudzenia poprzez receptor NMDA stosowano m.in. glicynę – aminokwas o najprostszej budowie i szerokim rozpowszechnieniu, podstawowy przekaźnik neuronów glicynergicznych, zaliczany do klasy I neurotransmiterów, pełniący ponadto funkcję koagonisty i modulatora, m.in. w obrębie układu glutaminianergicznego. W 2005 r. ukazała się metaanaliza badań, z której wynika, że glicyna i D-seryna istotnie zmniejszają nasilenie objawów negatywnych. Celem badania było ustalenie, czy dołączenie przez okres 6 tygodni glicyny lub donepezilu do dotychczasowego leczenia przeciwpsychotycznego w sposób istotny statystycznie wpływa na zmianę nasilenia objawów pozytywnych, negatywnych, ogólnej psychopatologii u pacjentów w stabilnym okresie choroby. Badaniu poddano grupę 62 osób w wieku 18-55 lat, chorych na schizofrenię paranoidalną (DSM-IV), w stanie psychicznym ustabilizowanym od co najmniej pół roku, bez zmiany w tym czasie rodzaju i dawki leku przeciwpsychotycznego. Zastosowano następujące metody: 1) potwierdzenie stabilizacji stanu psychicznego oraz stałej farmakoterapii przez wymagany okres na podstawie analizy dokumentacji medycznej, wywiadu i oceny aktualnego stanu; 2) augmentacja dotychczasowego leczenia przeciwpsychotycznego przez dodanie donepezilu lub glicyny oraz 3) ocena nasilenia objawów negatywnych, pozytywnych i psychopatologii ogólnej (PANSS) przed i po 6 tygodniach augmentacji donepezilem lub glicyną i występowania objawów niepożądanych. Wyniki: Istotne statystycznie różnice uzyskano po 6 tygodniach w grupie leczonych lekami przeciwpsychotycznymi oraz glicyną (przede wszystkim w zakresie objawów negatywnych i psychopatologii ogólnej, mniejsze w zakresie objawów pozytywnych), natomiast w grupie leczonej dodatkowo donepezilem nie stwierdzono takich różnic.
Źródło:
Psychiatria i Psychologia Kliniczna; 2005, 5, 4; 178-189
1644-6313
2451-0645
Pojawia się w:
Psychiatria i Psychologia Kliniczna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Massive inflammatory reaction following the removal of a ruptured silicone implant masking the invasive breast cancer – case report and literature review
Autorzy:
Nowaczyk, Piotr
Budnicka, Aleksandra
Wichtowski, Mateusz
Kurzawa, Paweł
Murawa, Dawid
Powiązania:
https://bibliotekanauki.pl/articles/1394062.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
breast augmentation
breast implants
breast implant rupture
silicone granuloma
breast cancer
Opis:
This paper presents a case of a patient with invasive ductal breast cancer following breast augmentation. Following breast implants rupture in March 2013 the breast implants have been removed – histopathological examination revealed leaked silicone with inflammatory infiltration, without evidence of cancerous lesions. Diagnostic imaging revealed multiple encapsulated silicone particles and clusters of post-inflammatory macrocalcifications in both breasts. In January 2014 the patient presented with symptoms of massive inflammation of the left breast. Following surgical consultation the patient had undergone radical left-sided mastectomy with lymphadenectomy. Postoperative histopathological examination revealed a multifocal advanced invasive ductal cancer G3 pT3pN3a (vascular invasion, metastases in 11 of 12 examined axillary lymph nodes). Following surgery the patient was qualified for further treatment – chemotherapy, radiotherapy, hormone therapy. The discussion includes a review of literature on the risk evaluation of co-occurrence of breast cancers in women with silicone breast implants and presents diagnostic challenges of breast cancer in this patient group.
Źródło:
Polish Journal of Surgery; 2016, 88, 1; 41-47
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Towards textual data augmentation for neural networks: synonyms and maximum loss
Autorzy:
Jungiewicz, Michał
Smywiński-Pohl, Aleksander
Powiązania:
https://bibliotekanauki.pl/articles/305750.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
deep learning
data augmentation
neural networks
natural language processing
sentence classification
Opis:
Data augmentation is one of the ways to deal with labeled data scarcity and overfitting. Both of these problems are crucial for modern deep-learning algorithms, which require massive amounts of data. The problem is better explored in the context of image analysis than for text; this work is a step forward to help close this gap. We propose a method for augmenting textual data when training convolutional neural networks for sentence classification. The augmentation is based on the substitution of words using a thesaurus as well as Princeton University's WordNet. Our method improves upon the baseline in most of the cases. In terms of accuracy, the best of the variants is 1.2% (pp.) better than the baseline.
Źródło:
Computer Science; 2019, 20 (1); 57-83
1508-2806
2300-7036
Pojawia się w:
Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies