Temat: atrophy - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl: a case report
Autorzy:: Borkowska, Anna
Jankowska, Agnieszka
Szlagatys-Sidorkiewicz, Agnieszka
Sztangierska, Beata
Liberek, Anna
Plata-Nazar, Katarzyna
Kamińska, Barbara
Powiązania:: https://bibliotekanauki.pl/articles/1039156.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: Spinal muscular atrophy
diabetes mellitus
children
Opis:: The spinal muscular atrophy is a rare autosomal recessive genetic disease characterized by the progressive loss of muscular strength. In its natural course the disease leads to death. Diabetes mellitus type 1 is an autoimmune metabolic disorder characterized by the disturbed insulin synthesis. This is a case report of an 8-year-old girl suffering from Werdnig Hoffman disease in whom DM1 was diagnosed. The unspecific clinical manifestation and diagnostic difficulties are presented in this paper. To the authors' knowledge, this is the first publication concerning the co-existence of these two medical conditions.
Źródło:: Acta Biochimica Polonica; 2015, 62, 1; 167-168
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Comparative study of bioresorbable membranes „Collapan” and „Collost” for the prevention of lower jaw atrophy
Autorzy:: Pohodenko-Chudakova, I.
Maksimovich, K.
Powiązania:: https://bibliotekanauki.pl/articles/284482.pdf
Data publikacji:: 2017
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: bioresorbable membrane
alveolar bone atrophy
Collost
Collapan
Opis:: Prevention of the alveolar bone atrophy represents one of the urgent problems in oral and maxillofacial surgery. The aim of the study was comparative evaluation of two osteoplastic bioresorbable membranes: “Collapan” made of collagen type II, hydroxyapatite and gentamycin sulphate, and “Collost” made of collagen type I for prevention of the mandible atrophy. 42 male patients aged from 45 to 70 years were involved in the clinical trial. Group 1, which was the reference group, included 20 individuals, in whom “Collapan” membrane was implanted to prevent atrophy of the alveolar bone. Group 2 included 22 patients, in whom “Collost” membrane with the same purpose was used. Clinical efficacy was assessed by analysis of the number of complications in the postoperative period. The level of the alveolar bone atrophy was assessed at the long-term follow-up (after 1 year) based on the parameters of the mandibular bone tissue determined by cone-beam computed tomography. In the postoperative period in the group 1 there were revealed 6 (14%) cases of infectious-inflammatory complications – alveolitis, 2 (5%) of them were revealed after the third molar atypical removal and 4 (9%) after a complicated extraction of the tooth. In group 2 – 2 (5%) complications were reviled: 1 (2.5%) - alveolitis and 1 (2.5%) - forced tooth extraction. The use of the “Collost” membrane allowed maintaining the height of the alveolar bone in patients during the observation period. The results obtained in the trial allow us to conclude that the use of the osteoplastic bioresorbable membrane “Collost” is most appropriate for prevention of the alveolar part of the lower jaw atrophy.
Źródło:: Engineering of Biomaterials; 2017, 20, 142; 7-10
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: Detection of IL-1β, IL-6 and TNF-αin Sprague-Dawely rats’ atrophic thymus induced by lipopolysaccharide
Autorzy:: Zhong, Y.B.
Zhang, X.L.
Lv, M.Y.
Hu, X.F.
Li, Y.
Powiązania:: https://bibliotekanauki.pl/articles/2087664.pdf
Data publikacji:: 2018
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: lipopolysaccharide
pro-inflammatory cytokines
thymus atrophy
rat
Źródło:: Polish Journal of Veterinary Sciences; 2018, 21, 3; 589-597
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: Hyperglycemia induced C2C12 myoblast cell cycle arrest and skeletal muscle atrophy by modulating sirtuins gene expression in rats
Autorzy:: Surinlert, P.
Thitiphatphuvanon, T.
Khimmaktong, W.
Pholpramool, C.
Tipbunjong, C.
Powiązania:: https://bibliotekanauki.pl/articles/2087134.pdf
Data publikacji:: 2021
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: diabetic mellitus
hyperglycemia
muscle atrophy
sirtuins
skeletal muscle
Źródło:: Polish Journal of Veterinary Sciences; 2021, 24, 4; 563-572
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 5.

Tytuł:: Monitoring and evaluation of muscle atrophy: a much needed step in critically ill COVID-19 patients
Autorzy:: Kumar, Amarjeet
Kumar, Abhyuday
Kumar, Neeraj
Kumar, Ajeet
Sinha, Chandni
Kumari, Poonam
Singh, Veena
Powiązania:: https://bibliotekanauki.pl/articles/29432087.pdf
Data publikacji:: 2021-03
Wydawca:: Towarzystwo Pomocy Doraźnej
Tematy:: COVID-ARDS
elderly
immobilization
muscle atrophy
noninvasive ventilation
Opis:: INTRODUCTION: Elderly COVID-19 patients admitted to the intensive care unit (ICU) are at high risk of an inflammatory syndrome, hypercatabolic reaction, malnutrition, and physical immobilization. This may result in loss of muscle mass and pulmonary infection leading to prolonged ventilatory support. Factors responsible for muscle mass loss in ICU are (1) microcirculatory disturbances, (2) presence of systemic inflammatory response syndrome (SIRS), (3) sepsis (4) drugs (corticoids, neuromuscular blockers) having inhibitory activity on the nervous system, neuromuscular junction and muscle itself. Mechanism of muscle atrophy in critically ill elderly patients include an imbalance between protein synthesis and degradation. Interventions to manage muscle atrophy for the patients admitted to ICU is also extrapolated to mechanically ventilated COVID-ARDS patients. PURPOSE: Early recognition of factors contributing to intensive care unit acquired weakness (ICUAW) in COVID-19 patients, inflammation, high catabolic phase, steroid use, and paralysis. The potential interventions to target these specific mechanisms and ameliorate muscle dysfunction in COVID-19 patients. CONCLUSIONS:Intensive care unit acquired weakness (ICUAW) in critically ill COVID-19 patients is due to severity of illness, co-morbidities, muscle unloading, or ICU treatments, a systemic reaction circulating within the body, or combinations therein. Furthermore, the availability of a culture model of ICUAW could facilitate in expediting the diagnosis of ICUAW and fast track the discovery of putative treatments. We recommend NIV or HFNC ventilation or early weaning from invasive mechanical ventilation in critically ill COVID-19 elderly patients.
Źródło:: Critical Care Innovations; 2021, 4, 1; 30-43
2545-2533
Pojawia się w:: Critical Care Innovations
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 6.

Tytuł:: Repair of the peripheral nerve gap with epineural sheath conduit to prevent muscle denervation atrophy in the diabetic rat model
Autorzy:: Łukaszuk, Mirosław
Kwiecień, Grzegorz
Madajka, Maria
Uygur, Safak
Drews, Michał
Siemionow, Maria
Powiązania:: https://bibliotekanauki.pl/articles/1396247.pdf
Data publikacji:: 2013-07-01
Wydawca:: Index Copernicus International
Tematy:: muscle denervation atrophy
peripheral nerve repair
diabetes
animal model
Opis:: Muscle denervation atrophy is a result of lower motor neuron injury, thus an early restitution of muscle stimulation is essential in prevention of atrophic changes. The aim of the study was to evaluate the new application of naturally occurring epineural sheath conduit in repair of the peripheral nerve gap to prevent development of muscle denervation atrophy. Material and methods. We used the model of 20 mm sciatic nerve gap, resulting in denervation atrophy of the gastrocnemius muscle in the diabetic rats (DM type 2, n=42, Zucker Diabetic Fatty strain). We applied the epineural sheath conduit created from the autologous sciatic nerve for gap repair. Muscle atrophy was assessed with the Gastrocnemius Muscle Index (GMI) and microscopic muscle morphometry (mean fiber area) at 6 and 12 postoperative week. Muscle regeneration in the experimental group was compared to the gold-standard technique of autologous nerve grafting for the repair of created nerve gap. Results. The GMI evaluation revealed comparable muscle mass restoration in groups with nerve repair using both epineural sheath and standard autologous nerve grafting (reaching 28 and 35% of contralateral muscle mass at 12 postoperative week, respectively, p=0.1), and significantly better restoration when compared to the negative control group (no repair, 20%, p<0.01). Micromorphometry confirmed significantly larger area of the regenerated muscle fibers in groups with both nerve grafting and epineural sheath conduit repair (reaching for both ca. 42% of the non-operated side), when compared to severe atrophic outcome when no nerve repair was performed (14% of the control fiber area, p<0.0001). The effectiveness of epineural conduit technique in muscle mass restoration was observed between 6 and 12 weeks after nerve repair - when gastrocnemius muscle mass increased by 12%. Conclusions. Peripheral nerve gap repair with naturally occurring epineural sheath conduit is effective in prevention of muscle denervation atrophy. This method is applicable in diabetic model conditions, showing results of regeneration which are comparable to the autologous nerve graft repair
Źródło:: Polish Journal of Surgery; 2013, 85, 7; 387-394
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 7.

Tytuł:: Zanik wieloukładowy typu C (MSA-C) – aspekty kliniczne i radiologiczne, opis przypadku
Clinical and radiological features of multiple system atrophy type C. Case report
Autorzy:: Węglewski, Arkadiusz
Juryńczyk, Jacek
Ślusarek, Izabela
Powiązania:: https://bibliotekanauki.pl/articles/1061185.pdf
Data publikacji:: 2006
Wydawca:: Medical Communications
Tematy:: autonomic failure
cerebellar atrophy
magnetic resonance
multiple system atrophy
orthostatic hypotension
rezonans magnetyczny
zanik móżdżku
zanik wieloukładowy
niewydolność autonomiczna
hipotonia ortostatyczna
Opis:: Multiple system atrophy (MSA) is a relatively rare degenerative disease of the central nervous system. The prevalence of MSA is about 2-4/100,000. The disease is included to synucleinopathies. The most characteristic neuropathological findings in MSA is argyrophilic glial cytoplasmatic inclusions in oligodendroglia which is composed of α-synuclein and ubiquitin. At present two main forms of the MSA are known: MSA-P and MSA-C. Symptoms of parkinsonism with rigidity and bradykinesia are more typical in MSA-P. Cerebellar signs are more characteristic for MSA-C. Severe autonomic failure, initially or during further clinical course stwierin MSA-P and MSA-C is present in most patients. The main symptoms of autonomic failure are orthostatic hypotension, urinary and less commonly fecal incontinence, impotence. In 1998 consensus on the diagnosis of MSA was established. The authors described a case of 61-year-old woman with 3 years of symptoms of cerebellar dysfunction followed by Parkinson’s syndrome and autonomic failure. MRI of the brain revealed severe atrophy of the cerebellum and brain stem, and “hot cross bun sign” in pons. Tilt-test confirmed orthostatic hypotension. Treatment with L-dopa and midodrin was moderately effective. The authors described problems of diagnostics, especially role of MRI, and actual problems of epidemiology, pathogenesis and treatment of MSA.
Zanik wieloukładowy (MSA) jest rzadką chorobą zwyrodnieniową ośrodkowego układu nerwowego. Występuje z częstością ocenianą na 2-4/100.000 i zaliczany jest do synukleinopatii. Najbardziej charakterystyczną cechę neuropatologiczną stanowi obecność srebrnochłonnych wtrętów cytoplazmatycznych w komórkach oligodendrogleju, zawierających α-synukleinę i ubikwitynę. Obecnie wyróżnia się dwie główne formy MSA: MSA-P i MSA-C. W MSA-P dominują objawy parkinsonizmu, głównie sztywność, spowolnienie, a w MSA-C – objawy uszkodzenia móżdżku. W obu formach typowe są nasilone objawy dysfunkcji układu autonomicznego, głównie hipotonia ortostatyczna, zaburzenia zwieraczy oraz impotencja. W 1998 roku ustalono kryteria diagnostyczne MSA. Autorzy przedstawiają przypadek 61-letniej chorej z mniej więcej 3-letnim wywiadem zespołu móżdżkowego, do którego dołączyły się następnie objawy autonomiczne i parkinsonowskie. Badanie MR głowy ujawniło charakterystyczne dla formy MSA-C dużego stopnia zanik móżdżku, pnia mózgu oraz objaw „krzyża” w moście. Test pionizacyjny wskazał na ciężką hipotonię ortostatyczną. Leczenie L-dopą w umiarkowany sposób zmniejszyło nasilenie zespołu parkinsowskiego, a midodrinem – hipotonii ortostatycznej. Autorzy omawiają problemy diagnostyki MSA, ze szczególnym uwzględnieniem roli badania MR, oraz przedstawiają aktualny stan wiedzy na temat patogenezy, epidemiologii i terapii MSA.
Źródło:: Aktualności Neurologiczne; 2006, 6, 1; 48-53
1641-9227
2451-0696
Pojawia się w:: Aktualności Neurologiczne
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 8.

Tytuł:: Can olive oil prevent distal colon mucosal atrophy caused by disuse in rats with colostomy? An experimental animal study
Autorzy:: Atıcı, Ahmet
Demir, Emel
Gürsoy, Didar
Çelikkaya, Mehmet
Akçora, Bülent
Powiązania:: https://bibliotekanauki.pl/articles/1391554.pdf
Data publikacji:: 2021
Wydawca:: Index Copernicus International
Tematy:: children
distal colon mucosal atrophy caused by disuse
olive oil
Opis:: Aim: This study aims to investigate the effects of pure olive oil on mucosal atrophy of the distal colon in rats. Material and methods: The study included 28 male albino Wistar rats weighing 300–350 g. A total of 28 animals were randomly allocated to four groups: group 1: control group (n = 6); group 2: ostomy group (n = 6); group 3: ostomy + saline group (n = 8); group 4: ostomy + olive oil group (n = 8). By definition, group 1 did not undergo any procedure. The same surgical procedure was performed for groups 2, 3, and 4 as described below. In all animals from these groups, a two-centimeter-long mid-line incision was made and the colon was divided into 5 cm sections, measured from the distal colon to the caecum. Proximal and distal stomas were created 2 cm apart in the midline with the use of single-layer interrupted sutures. All rats were kept under close daily observation until they were terminated postoperatively after the 1st month. Animals from group 2 did not undergo any additional procedures, while those fromgroups 3 and 4 were given 2 mL of saline and olive oil twice a day, respectively. At the end of the 1st month, the rats were re-operated through the same approach. Biopsies were taken from the proximal and distal stomas of all rats in the same manner for further histopathological analysis. Results: Group 1 showed no significant differences in terms of mucosal thickness, muscular thickness, wall thickness or colonic lumen diameter between the proximal and distal segments of the colon. Although there were significant differences between the proximal and distal colostomies for each parameter in groups 2, 3, and 4, the mucosal thickness, muscular thickness, wall thickness, and colonic lumen diameter differences for proximal and distal ostomies were very small in group 4 when compared to groups 2 and 3. Conclusion: The administration of pure olive oil through the distal colon before colostomy closure may reduce the difference in diameter between the proximal and distal intestinal segments. As a result, a more straightforward surgical procedure may be achieved.
Źródło:: Polish Journal of Surgery; 2021, 93, 4; 35-40
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 9.

Tytuł:: The application of High-Speed camera (HS), acoustic analysis and Voice Handicap Index (VHI) questionnaire in diagnosis of voice disorders in elderly men
Autorzy:: Kosztyła-Hojna, Bożena
Zdrojkowski, Maciej
Duchnowska, Emilia
Powiązania:: https://bibliotekanauki.pl/articles/1397805.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: acoustic voice analysis
HSDI
hypofunctional dysphonia
presbyphonia
vocal fold atrophy
Opis:: Objective: The process of ageing begins after 60 years of age and is referred to as presbyphonia (Vox senium). The causes include functional or organic voice disorders, often coexisting with dry upper respiratory tract infection. Introduction: The aim of the study is the use of high-speed camera and acoustic voice analysis in diagnostics of the clinical form of presbyphonia. M aterials and methods: The study included a group of 50 men, non-smokers, age from 51 to 72, who do not use their voice professionally. High-Speed Digital Imaging and HS camera have been used, allowing evaluation of real vibrations of vocal folds, along with acoustic voice analysis using a software by DiagNova Technologies. Results: VHI questionnaire has been used for self-assessment of voice disability. Visualizations of the larynx enabled recognition of hypofunctional dysphonia or atrophy of vocal folds that cause voice disorders. This was confirmed by parameters of voice acoustic evaluation: F0, NHR, narrowband spectrography. The pathological value of NHR and the presence of nonharmonic components in the range of high frequency levels indicated glottal insufficiency, recorded with the visualization technique of the larynx by HS camera. A significant shortening of maximum phonation time in relation to the control group has also been recorded. Discussion: The objective examination of voice pathology is crucial in diagnosis and rehabilitation, however, subjective assessment of the patient is important in the scope of the procedure used. The patient’s subjective self-rating assessment (VHI) confirmed the sense of voice disorders in elderly men, indicating the need for rapid and accurate clinical diagnosis.
Źródło:: Polish Journal of Otolaryngology; 2019, 73, 5; 25-30
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 10.

Tytuł:: Traumatic “TERSON SYNDROME PLUS”: Pneumocephalocele with optic atrophy
Autorzy:: Chowdhury, Sanjoy
Srivastava, Madhumita
Chowdhury, Nilanjan
Powiązania:: https://bibliotekanauki.pl/articles/2037682.pdf
Data publikacji:: 2020-06-30
Wydawca:: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:: optic atrophy
sub retinal
subarachnoid hemorrhage
sub hyaloid
Terson syndrome plus
Opis:: Introduction. Terson Syndrome is subarachnoid hemorrhage (SAH) with sub retinal hemorrhage flowing through channel. Reduced vision in such fresh case is due to hemorrhage itself, blocking macula/other photo receptors in the long run macular cellophane retinopathy which causes profound visual loss. SAH causes neurological problems which can become a risk factor for evacuating blood from vitreous. Hypertension is commonest cause to cause Terson Syndrome, but trauma is also devastating cause as it can lead to irreversible visual consequences like total loss of perception of light or blindness. Aim. Here we describe a case of Terson Syndrome plus disease features SAH in frontal lobe. Description of the case. When there is traumatic pneumocephalocele, it gives space to blood to imbibe towards bony optic canal and form hematoma around nerve sheath which causes compression around the same and leads to optic atrophy. Optic nerve can be injured by direct traumatic dissection during road traffic accidents (RTA), but even without that blood may accumulate around optic nerve and in turn leads to formation of hematoma and subsequently pressure induced optic atrophy. Moreover, blood can slowly travel to sub hyaloid space/sub retinal space (beneath internal limiting membrane or sub ILM) with probable gliosis covering typical boat shaped blood as seen in this case. This sub ILM hemorrhage or gliosis may have resolved through three injections of Triamcinolone in the orbital floor (OFTA) near apex, but optic atrophy snatches vision. This protocol was followed to treat traumatic compressive (peri optic hematoma) optic neuropathy and traumatic retinopathy associated with sub hyaloid hemorrhage. Conclusion. Diagnosis of Terson syndrome plus disease was established by addressing all features on computed tomography (CT) scan and magnetic resonance imaging (MRI). Plus, features include pneumocephalus, optic nerve sheath hematoma, optic atrophy and gliosis over sub-hyaloid hemorrhage, typical boat shaped. The part of hemorrhage still endured as seen on optical coherence topography, but vision was lost by virtue of optic atrophy. OCT shows clot in sub hyaloid space
Źródło:: European Journal of Clinical and Experimental Medicine; 2020, 2; 116-120
2544-2406
2544-1361
Pojawia się w:: European Journal of Clinical and Experimental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "atrophy" wg kryterium: Temat

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język