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    Wyświetlanie 1-10 z 10
    Tytuł:
    The evaluation of adhesion between electrospun collagen layers and different titanium substrates
    Autorzy:
    Sedlacek, R.
    Suchy, T.
    Supova, M.
    Sucharda, Z.
    Kuzma, J.
    Horny, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/285558.pdf
    Data publikacji:
    2016
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    antibiotic treatment
    collagen layers
    titanium alloys
    Źródło:
    Engineering of Biomaterials; 2016, 19, 138; 16
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Current status of Helicobacter pylori associated human gastric cancer and the therapeutic approaches – A Review
    Autorzy:
    Pal, Partha
    Powiązania:
    https://bibliotekanauki.pl/articles/1189965.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Helicobacter pylori
    Gastric carcinoma
    Peptic ulcers
    Antibiotic treatment
    Opis:
    In the recent years one of the common causes of cancer related deaths in humans is associated with the development of gastric carcinoma leading to gastric cancer. It had long before reported that the potent agent that is intimately related with the gastric cancer is the infection of the bacterium Helicobacter pylori (H. pylori). H. pylori infection in humans is characterised by the development of acute peptic ulcers which creates a lots of gastroenterological symptoms. Co-existence of H. pylori in the human gastric environment is well adapted by the pathogen by evading the immune responses of the host. Gastric biopsy in patients suffering from H. pylori infection reported the development of gastric lesions having the chance to proceed towards development gastric cancer. Recently it was reported that eradication of the H. pylori colonization is not possible even after continued current antibiotic treatment over long periods and even combined regimes are unsuccessful.Moreover alterations of the genetic background of the host gastric cells were also reported along with infection of H. pylori, the primary concern for the evolution of the genetically transformed cells which is the hallmark for the development of malignancy. Clinical studies have reported the limited efficacy in decreasing the incidence of gastric carcinoma even after the eradication therapy has been completed for the bacterial colonization. Research based on the biopsy specimens obtained from conventional gastric endoscopy of affected patients has revealed some genetic or epigenetic alterations in the gastric mucosa. The cause of concern to human life lies in the fact that the number of sporadic cases of primary or metachronous gastric carcinoma has increased after successful eradication.The purpose of the present review is to assess the current status of the research based on the concept of development of gastric carcinoma in association with H. pylori infection in humans and to throw some light in the remedial measures against the pathogen which is a chronic burden in the well-being of the human society.
    Źródło:
    World Scientific News; 2016, 52; 162-180
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acute sinusitis in daily clinical practice
    Autorzy:
    Arcimowicz, Magdalena
    Powiązania:
    https://bibliotekanauki.pl/articles/23211721.pdf
    Data publikacji:
    2021-08-26
    Wydawca:
    Index Copernicus International
    Tematy:
    acute bacterial sinusitis
    acute post-viral sinusitis
    acute sinusitis
    antibiotic treatment
    cold
    diagnostics
    epidemiology
    EPOS
    integrated care pathways
    intranasal corticosteroids
    phytotherapy
    rhinosinusitis
    treatment
    Opis:
    Understanding the appropriate use of diagnostics and treatment in acute rhinosinusitis is of immense importance given the high prevalence of this disease in the general population. The ability to differentiate between the principal phenotypes of acute sinusitis, namely acute viral infection (cold), acute post-viral sinusitis and acute bacterial sinusitis, determines the future management and is fundamental to providing rational therapeutic recommendations – especially as regards antibiotic treatment, which is very often overused in acute sinusitis even though bacterial phenotypes only account for 0.5–2% of all cases of the disease. The latest therapeutic recommendations contained in the EPOS2020 position paper introduce a system based on integrated care pathways (ICPs), which comprise pharmacy-supported self-care and e-health as the first level, followed by primary care as the second, with specialist care being reserved for patients who develop a more severe course of the disease, have suspected complications or suffer from recurrent acute sinusitis. Management of acute sinusitis is primarily based on symptomatic treatment modalities, with phytotherapeutic support, as well as on antiinflammatory treatment, while antibiotic therapy is used in very specific and limited indications. Complications are relatively rare in acute sinusitis and they are not considered to be associated with antibiotic intake. Considering the high prevalence of acute forms of sinusitis, their significant impact on quality of life and high direct and indirect costs of treatment, the right diagnosis and management, without unnecessary escalation of therapy, can substantially translate into a number of public health benefits.
    Źródło:
    Polish Journal of Otolaryngology; 2021, 75, 4; 40-50
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevalence of Beta Lactamases Genes in Sewage and Sludge Treated in Mechanical-Biological Wastewater Treatment Plants
    Autorzy:
    Zieliński, Wiktor
    Buta, Martyna
    Hubeny, Jakub
    Korzeniewska, Ewa
    Harnisz, Monika
    Nowrotek, Monika
    Płaza, Grażyna
    Powiązania:
    https://bibliotekanauki.pl/articles/124493.pdf
    Data publikacji:
    2019
    Wydawca:
    Polskie Towarzystwo Inżynierii Ekologicznej
    Tematy:
    WWTP
    beta-lactamases
    wastewater treatment
    antibiotic resistance genes
    Opis:
    Wastewater treatment plants (WWTPs) are a very important link in the spread of antibiotic resistance genes to the environment and the formation of antibiotic-resistant microorganisms. The mechanical and biological methods of wastewater treatment in WWTPs do not completely remove the resistance genes from sewage. The genes responsible for extended-spectrum beta-lactamases (ESBLs) are very common in the family Enterobacteriaceae that colonize the human digestive tract and are abundant in wastewater. The aim of this study was to analyze the prevalence of genes encoding beta-lactamases in the wastewater and sludge samples collected from two WWTPs in the Polish regions of Warmia and Silesia and from the river water upstream and downstream from the WWTPs. The wastewater samples were passed through polycarbonate membrane filters, whereas the sludge samples were homogenized, and genomic DNA was extracted. The blaTEM, blaOXA and blaSHV genes were detected by means of standard PCR. The most prevalent gene was blaTEM which occurred in all samples, including the treated wastewater. The blaOXA gene was also frequently detected in all samples from the WWTP in Silesia. The blaSHV gene was least prevalent in the tested samples. These results indicate that wastewater is a hotspot for resistant bacteria. Beta-lactamase genes are not eliminated through the mechanical-biological wastewater treatment methods, and they can spread to other environments, thus increasing the pool of antibiotic resistance genes around the world and creating epidemiological risks.
    Źródło:
    Journal of Ecological Engineering; 2019, 20, 9; 80-86
    2299-8993
    Pojawia się w:
    Journal of Ecological Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Damage of Facial Soft Tissues as a Result of Being Bitten by a Dog
    Autorzy:
    Zielińska-Kaźmierska, Bogna
    Wieczerzak, Leszek
    Kozioł, Agnieszka
    Majkowska, Karolina
    Arkuszewski, Piotr
    Manowska, Bogusława
    Powiązania:
    https://bibliotekanauki.pl/articles/1395792.pdf
    Data publikacji:
    2014-08-01
    Wydawca:
    Index Copernicus International
    Tematy:
    wound bitten
    dog
    antibiotic prophylaxis
    treatment of wounds
    Opis:
    Being bitten by a dog can have serious health effects. That is why, never underestimate even the smallest soft tissue injuries inflicted by aggressive animals. This incident may have an impact on the further condition of a patient. From our first aid will also depend the aesthetic and functional effect of the scar on the face. We should pay attention to the use of antibiotic prophylaxis. The aim of the study was to perform the analysis of the soft tissue bitten injuries made by dogs in patients treated in the years 2004‑2009 in the Clinic of Cranio-Maxillo-Facial and Oncological Surgery in Łódź. The most frequent attacked areas were analyzed in the cases of single and multiple face wounds. The dependence of the dog attacks and the alcohol consumption by the victims. The use of an early antibiotic prophylaxis and the number of the infectious complications. Material and methods. The material studied is a group of 26 patients, including 17 women and 9 men. In the majority patients were older than 20 years old. Results. The analysis of our data shows that most of the victims were aged 19-30 and 51-60 years. 14 patients have been mutilated on one area of the face, the remaining patients at least two areas. Most injuries underwent upper or lower lip. In all cases, the initial supply has been applied to the wounds. Antibiotic prophylaxis was used in 23 patients. In one of the other three cases, patient who have not been applied to the prevention of complications in the form of phlegmon face. Half of the attack dogs have been known to the victims. All patients had implemented prevention of tetanus, or held-to-date vaccinations. In eight cases, patients reported that at the time of the event they were under the influence of alcohol. Conclusions. Primary supply of bitten wounds of face at the moment seems to be the standard. In our study, in cases where patients has been treated with an antibiotic, there was no case of infection in the wound. Late complication in the form of phlegmon occurred in one patient who had not used prophylaxis. As the most of the authors note lower lip is the most vulnerable for the bite in the case of adult people. Analysis of our data is consistent with these reports. It has also been found that people under the influence of alcohol are often attacked by unknown dogs.
    Źródło:
    Polish Journal of Surgery; 2014, 86, 8; 364-369
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of the BIOLOG system for characterization of Serratia marcescens ss marcescens isolated from onsite wastewater technology (OSWT)
    Autorzy:
    Chojniak, Joanna
    Jałowiecki, Łukasz
    Dorgeloh, Elmar
    Hegedusova, Berta
    Ejhed, Helene
    Magnér, Jörgen
    Płaza, Grażyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1038922.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    onsite wastewater treatment
    Biolog system
    Serratia spp.
    antibiotic resistance
    Opis:
    The scope of this study was to apply the Biolog system to identify and characterize a Serratia strain isolated from the surface of black plastic pieces which constitute the fluidized bed filter (onsite wastewater technology, OSWT). The preliminary isolation of the strain was done in the medium with tetracycline at a 16 mg/l concentration. To characterize the isolated strain, the following Biolog methods were applied: (1) EcoPlates microplates for evaluation of physiological profiling, (2) GEN III OmniLog® ID System for identification of the isolate, and (3) phenotypic microarrays (PM) technology for evaluation of sensitivity to antibiotics (PM11 and PM12). Results were recorded using the original OmniLog® software. The Serratia strain was identified as Serratia marcescens ss marcescens with similarity index 0.569. The same identification was obtained by the 16S rDNA analysis. PM analysis showed an enhancement of phenotype (resistance or growth) of this strain to 35 antibiotics. The loss of phenotype (sensitivity or non-growth) was observed only for 5 antibiotics: lomefloxacin (0.4 µg/ml), enoxacin (0.9 µg/ml), nalidixic acid (18.0 µg/ml), paromomycin (25.0 µg/ml) and novobiocin (1100 µg/ml). This study acknowledges that the methods proposed by the Biolog system allow correct and complete identification and characterization of the microbes isolated from different environments. Phenotypic microarrays could be successfully used as a new tool for identification of the multi-antibiotic resistance of bacteria and for determination of the minimal inhibition concentrations (MIC).
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 4; 799-805
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effects of season and processing technology on the abundance of antibiotic resistance genes in air samples from municipal wastewater treatment and waste management plants
    Autorzy:
    Osińska, Adriana
    Jachimowicz, Piotr
    Niestępski, Sebastian
    Harnisz, Monika
    Korzeniewska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/2032941.pdf
    Data publikacji:
    2021
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    municipal wastewater
    antibiotic resistance
    wastewater treatment plant
    rRNA
    ścieki komunalne
    odporność na antybiotyki
    oczyszczalnia ścieków
    Opis:
    This study aimed to perform a qualitative and a quantitative assessment of the prevalence of genes encoding resistance to beta-lactam, tetracycline, and chloramphenicol antibiotics in samples of DNA isolated from air in a municipal wastewater treatment plant (WWTP) and a municipal waste management plant (WMP). Air samples were collected in the mechanical (MP) and biological (BP) processing units of WWTP and WMP in winter and spring. The samples of air were collected by impingement into PBS solution and subsequently, DNA was isolated. The prevalence of the 16S rRNA gene and ARGs was determined by PCR, and the most abundant ARGs were quantified by qPCR. The highest diversity of the analyzed ARGs was noted in air samples collected in the mechanical processing units of the WWTP (winter) and the WMP (spring). The copy of ARGs varied between treatment units and seasons. ARGs were most abundant in air samples collected in spring in the MP units of both the WWTP and the WMP. The study demonstrated that ARGs are ubiquitous in the air in both WWTPs and WMPs. The presence of ARGs in the air can exert a negative impact on the health of plant employees.
    Źródło:
    Environment Protection Engineering; 2021, 47, 1; 101-114
    0324-8828
    Pojawia się w:
    Environment Protection Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Strategies for Helicobacter pylori eradication in 1995: A review of international and Belgian experience
    Autorzy:
    Deltenre, M
    Jonas, C.
    Otero, J.
    Cozzoli, A.
    Denis, P.
    Burette, A.
    De Koster, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/69033.pdf
    Data publikacji:
    1996
    Wydawca:
    Polskie Towarzystwo Fizjologiczne
    Tematy:
    macrolide
    bacterial resistance
    in vivo
    in vitro
    Helicobacter pylori
    omeprazole
    peptic ulcer
    gastric milieu
    acid secretion
    treatment
    antibiotic
    microorganism
    gastroduodenal disorder
    stomach
    amoxicillin
    eradication
    Źródło:
    Journal of Physiology and Pharmacology; 1996, 47, 1
    0867-5910
    Pojawia się w:
    Journal of Physiology and Pharmacology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Czy mamy skuteczny lek w leczeniu bakteryjnych zakażeń górnych dróg oddechowych o mnogiej lokalizacji?
    Is there a cure for bacterial infections of the upper respiratory tract with multiple locations?
    Autorzy:
    Makowska, Magdalena
    Sybilski, Adam J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1033121.pdf
    Data publikacji:
    2014
    Wydawca:
    Medical Communications
    Tematy:
    amoxicillin with clavulanic acid
    children
    rational antibiotic therapy
    treatment
    upper respiratory tract infections
    infekcje górnych dróg oddechowych
    racjonalna antybiotykoterapia
    amoksycylina z kwasem klawulanowym
    leczenie
    dzieci
    Opis:
    Upper respiratory tract infections (often with multiple locations) are a common problem, especially in the GP’s office. These infections account for about 50–60% of all community-acquired infections and are the most common cause of fever in infants and young children. Most are viral infections. Bacterial factors are S. pneumoniae, H. influenzae and M. catarrhalis. The basic procedure is a detailed medical anamnesis, a careful examination and determination of the likely aetiology of the infection. The decision to empirically treat the infection is generally based on the initial differential diagnosis, without the need for a microbiological examination. In case of a viral infection, a symptomatic treatment is sufficient. In the case of suspected bacterial aetiology, is bacteriological confirmation is not suitable, but empirical antibiotic therapy should be implemented. Physicians must pay attention particularly to compliance. Without compliance the treatment generally fails. Currently, physicians have antibiotics (such as amoxicillin with clavulanic acid) which in terms of efficiency and safety are almost ideal drugs. Among the features of an ideal antibiotics we may find: spectrum of effect covering the most common pathogens, efficiency, bioavailability, multiple dosage form, safety, availability and a low cost of treatment. In case of complications or failure of the therapy the exact aetiology should be determined (bacteriological, virological, mycological examination) and hospitalisation should be considered. Following and respecting such scheme of behaviour may contribute to a faster and more efficient treatment of the upper respiratory tract infections, decrease the number of complications, which is equally important, and reduce direct and indirect costs of the therapy.
    Infekcje górnych dróg oddechowych (nierzadko z mnogą lokalizacją) są częstym problemem, zwłaszcza w gabinecie lekarza rodzinnego. Infekcje te stanowią około 50–60% wszystkich zakażeń pozaszpitalnych, będąc główną przyczyną gorączki u niemowląt i małych dzieci. Zazwyczaj są to infekcje wirusowe, z bakteryjnych czynników przeważają S. pneumoniae, H. influenzae oraz M. catarrhalis. Podstawowym postępowaniem jest szczegółowa analiza wywiadu, dokładne badanie przedmiotowe pacjenta i ustalenie prawdopodobnej etiologii infekcji. Decyzja o wdrożeniu leczenia z reguły bazuje na wstępnym różnicowym rozpoznaniu – nie ma konieczności wykonywania dokładnego badania mikrobiologicznego. W przypadku zakażenia wirusowego wskazane i wystarczające jest leczenie objawowe. W razie podejrzenia etiologii bakteryjnej (na co wskazują charakterystyczne objawy podmiotowe i przedmiotowe lub ewentualne badania laboratoryjne) nie jest wskazane potwierdzanie bakteriologiczne, należy natomiast wdrożyć antybiotykoterapię empiryczną. Lekarz musi zwrócić szczególną uwagę na przestrzeganie przez pacjenta zaleceń lekarskich (compliance) – jego brak jest najczęstszą przyczyną niepowodzenia terapii. Obecnie lekarze dysponują antybiotykami (np. amoksycylina z kwasem klawulanowym), które pod względem skuteczności i bezpieczeństwa są lekami niemal idealnymi. Spośród właściwości idealnego antybiotyku należy wymienić: spektrum działania obejmujące najczęstsze patogeny, skuteczność, dobrą biodostępność, wiele postaci leku, bezpieczeństwo, dostępność i niskie koszty leczenia. W przypadku wystąpienia powikłań lub niepowodzenia terapii trzeba ustalić dokładną etiologię (badanie bakteriologiczne, wirusologiczne, mikologiczne) oraz rozważyć leczenie w warunkach szpitalnych. Przestrzeganie takiego schematu postępowania może przyczynić się do szybszej i skuteczniejszej terapii infekcji górnych dróg oddechowych, zmniejszenia liczby powikłań oraz redukcji kosztów bezpośrednich i pośrednich choroby.
    Źródło:
    Pediatria i Medycyna Rodzinna; 2014, 10, 2; 128-136
    1734-1531
    2451-0742
    Pojawia się w:
    Pediatria i Medycyna Rodzinna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Srebro jako alternatywa dla antybiotyków i leków przeciwwirusowych – nowe potencjalne wykorzystanie
    Autorzy:
    Hudemowicz, Piotr
    Pawłowska, Marta
    Łuszczyna, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/2078921.pdf
    Data publikacji:
    2022-07-01
    Wydawca:
    Wydawnictwo Naukowe Medyk sp. z o.o.
    Tematy:
    infekcje bakteryjne
    infekcje wirusowe
    SARS-CoV-2
    antybiotykooporność
    srebro nanocząsteczkowe
    srebro koloidowe
    srebro TIAB
    leczenie ran
    ginekologia
    okulistyka
    stomatologia
    bacterial infections
    viral infections
    antibiotic resistance
    nanoparticle silver
    colloidal
    silver
    TIAB silver
    wound treatment
    gynecology
    ophthalmology
    dentistry
    Opis:
    Infekcje bakteryjne i wirusowe stwarzają rosnący problem zdrowotny, co spowodowane jest w dużej mierze narastającą wśród populacji antybiotykoopornością i ograniczoną skutecznością leków przeciwwirusowych. Badania nowych form srebra opartych na technologiach nanocząsteczkowych, poza znanymi właściwościami antybakteryjnymi, potwierdziły również skuteczność przeciwwirusową. Nanocząsteczki srebra nie tylko działają na wiele bakterii i grzybów, ale również wykazują potencjał przeciw wirusom takim jak: zespół nabytej odporności (HIV), wirus zapalenia wątroby typu A i B, wirus opryszczki pospolitej (HSV), półpasiec, wirus grypy A/H1N1, wirus RSV oraz szereg koronawirusów czy wirus małpiej ospy. Nowoczesne formy srebra są coraz częściej wykorzystywane w produktach mających na celu eliminację groźnych dla zdrowia infekcji.
    Bacterial and viral infections pose a growing health problem, which is largely due to the increasing antibiotic resistance and limited effectiveness of antiviral drugs among the population. Research on new forms of silver based on nanoparticle technologies, in addition to the known antibacterial properties, also confirmed the antiviral effectiveness. Silver nanoparticles not only act against a number of bacteria and fungi, but also show potential against viruses such as: acquired immune syndrome (HIV), hepatitis A and B virus, herpes simplex virus (HSV), herpes zoster virus, influenza A / H1N1 virus, RSV and a number of coronaviruses and the monkey pox virus. Modern forms of silver are more and more often used in products aimed at eliminating infections that are dangerous to health.
    Źródło:
    Lek w Polsce; 2022, 372, 05; 11-16
    2353-8597
    Pojawia się w:
    Lek w Polsce
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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