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Wyszukujesz frazę "aging," wg kryterium: Temat


Tytuł:
Tocopherols in food rations of selected populations of the Wielkopolska Region. IV. Aged people
Autorzy:
Duda, G.
Powiązania:
https://bibliotekanauki.pl/articles/1371701.pdf
Data publikacji:
1993
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
health
man
food ration
aging
human nutrition
daily food ration
Wielkopolska region
tocopherol
population
Źródło:
Polish Journal of Food and Nutrition Sciences; 1993, 02, 2; 69-76
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wplyw wieku chronologicznego bulw matecznych ziemniaka na plonowanie odmian o zroznicowanym tempie fizjologicznego starzenia sie
Autorzy:
Rykaczewska, K
Powiązania:
https://bibliotekanauki.pl/articles/835335.pdf
Data publikacji:
1995
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
bulwy mateczne
wiek chronologiczny
tempo fizjologicznego starzenia
ziemniaki
starzenie sie roslin
plonowanie
odmiany roslin
mother tuber
chronological age
potato
plant aging
yielding
plant cultivar
Źródło:
Ziemniak Polski; 1995, 2; 31-34
1425-4263
Pojawia się w:
Ziemniak Polski
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wplyw wieku fizjologicznego bulw matecznych ziemniaka na rozwoj i plon odmian o zroznicowanym tempie fizjologicznego starzenia sie
Autorzy:
Rykaczewska, K
Powiązania:
https://bibliotekanauki.pl/articles/835786.pdf
Data publikacji:
1995
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
wiek fizjologiczny
bulwy mateczne
tempo fizjologicznego starzenia
rozwoj roslin
ziemniaki
plony
starzenie sie roslin
odmiany roslin
physiological age
mother tuber
plant development
potato
yield
plant aging
plant cultivar
Źródło:
Ziemniak Polski; 1995, 2; 35-44
1425-4263
Pojawia się w:
Ziemniak Polski
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characteristic properties of generalized order statistics from exponential distributions
Autorzy:
Kamps, Udo
Gather, Ursula
Powiązania:
https://bibliotekanauki.pl/articles/1339111.pdf
Data publikacji:
1997
Wydawca:
Polska Akademia Nauk. Instytut Matematyczny PAN
Tematy:
aging properties
generalized order statistics
exponential distribution
spacings
characterization
Opis:
Exponential distributions are characterized by distributional properties of generalized order statistics. These characterizations include known results for ordinary order statistics and record values as particular cases.
Źródło:
Applicationes Mathematicae; 1996-1997, 24, 4; 383-391
1233-7234
Pojawia się w:
Applicationes Mathematicae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Age dependent changes of insulin receptors in rat tissues
Autorzy:
Torlinska, T.
Mackowiak, P.
Nogowski, L.
Hryniewiecki, T.
Witmanowski, H.
Perz, M.
Madry, E.
Nowak, K.M.
Powiązania:
https://bibliotekanauki.pl/articles/69323.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
plasma membrane
hyperglycemia
hyperinsulinemia
aging
heart
insulin receptor
liver
rat
tissue
skeletal muscle
hormone
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 4,2
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Age-related alteration of poly(ADP-ribose) polymerase activity in different parts of the brain.
Autorzy:
Strosznajder, Joanna
Jęśko, Henryk
Strosznajder, Robert
Powiązania:
https://bibliotekanauki.pl/articles/1044356.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
PARP
aging
brain
Opis:
Poly(ADP-ribose) polymerase (PARP) is a conserved enzyme involved in the regulation of DNA repair and genome stability. The role of PARP during aging is not well known. In this study PARP activity was investigated in nuclear fractions from hippocampus, cerebellum, and cerebral cortex of adult (4 months), old adult (14 months) and aged (24-27 months) rats. Concomitantly, the free radical evoked lipid peroxidation was estimated as thiobarbituric acid reactive substances (TBARS). The specific activity of PARP in adult brain was about 25, 21 and 16 pmol/mg protein per min in hippocampus, cerebellum and cerebral cortex, respectively. The enzyme activity was higher in all investigated parts of the brain of old adults. In aged animals PARP activity was lower in hippocampus by about 50%, and was unchanged in cerebral cortex and in cerebellum comparing to adult rats. The concentration of TBARS was the same in all parts of the brain and remained unchanged during aging. There is no direct correlation between PARP activity and free radical evoked lipid peroxidation during brain aging. The lowered enzyme activity in aged hippocampus may decrease DNA repair capacity which subsequently may be responsible for the higher vulnerability of hippocampal neurons to different toxic insults.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 331-337
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aging and longevity genes.
Autorzy:
Jazwinski, S
Powiązania:
https://bibliotekanauki.pl/articles/1044350.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
longevity genes
Opis:
The genetics of aging has made substantial strides in the past decade. This progress has been confined primarily to model organisms, such as filamentous fungi, yeast, nematodes, fruit flies, and mice, in which some thirty-five genes that determine life span have been cloned. These genes encode a wide array of cellular functions, indicating that there must be multiple mechanisms of aging. Nevertheless, some generalizations are already beginning to emerge. It is now clear that there are at least four broad physiological processes that play a role in aging: metabolic control, resistance to stress, gene dysregulation, and genetic stability. The first two of these at least are common themes that connect aging in yeast, nematodes, and fruit flies, and this convergence extends to caloric restriction, which postpones senescence and increases life span in rodents. Many of the human homologs of the longevity genes found in model organisms have been identified. This will lead to their use as candidate human longevity genes in population genetic studies. The urgency for such studies is great: The population is graying, and this research holds the promise of improvement in the quality of the later years of life.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 269-279
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Barwa modelowego, surowo-dojrzewajacego produktu miesnego
Autorzy:
Klossowska, B M
Olkiewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/826253.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Technologów Żywności
Tematy:
barwa
peklowanie
stabilnosc barwy
azotan sodu
dojrzewanie miesa
czas dojrzewania
swiatlo
mieso
colour
pickling process
colour stability
sodium nitrate
meat aging
ripening time
light
meat
Opis:
Badano wpływ czasu dojrzewania, ilości dodanego azotanu oraz czasu naświetlania na barwę modelowego, surowo-dojrzewającego produktu mięsnego. Wyznaczono, przy użyciu aparatu Minolta CR- 300, współrzędne barwy L* a* b* C* i H°. W celu oceny trwałości barwy wyliczono wartości ∆E*. Zastosowane współrzędne dobrze opisywały zmiany barwy produktu surowo-dojrzewającego. Produkt po 3 miesiącach dojrzewania charakteryzował się najbardziej intensywną czerwoną barwą z najmniejszym przesunięciem odcienia w kierunku żółtej części spektrum. Zróżnicowane ilości dodanego azotanu nie wywarły istotnego wpływu na parametry barwy. Trwałość barwy produktów po 3 i 7 miesiącach dojrzewania była lepsza niż po 1 miesiącu. Uzyskane wyniki potwierdzają zaobserwowany wcześniej problem pogarszania się barwy peklowanych produktów mięsnych pod wpływem światła.
Effect of the ripening period, the amount of added nitrate and time of light exposure on the colour characteristics of model dry-cured meat product was study. Colour coordinates: L* (lightness), a* (redness), b* (yellowness), C* (chroma) and H° (hue) were determined using a Minolta CR-300. Colour stability was expressed as ∆E* values. The used colour coordinates were very useful for describing the colour changes of model dry-cured meat product. The product after 3 months of ripening showed the highest redness with the slightest shifting the hue toward the yellow part of the spectrum. The amount of added nitrate did not have significant influence on differentiation of all colour parameters. The colour stability in the model products after 3 and 7 months of ripening was better than after 1 month. The results obtained in this study confirmed existing problem with discoloration of cured meat displayed in light.
Źródło:
Żywność Nauka Technologia Jakość; 2000, 07, 1; 56-64
1425-6959
Pojawia się w:
Żywność Nauka Technologia Jakość
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Does senile impairment of cholinergic system in rats concern only disturbances in cholinergic phenotype or the progressive degeneration of neuronal cell bodies?
Autorzy:
Niewiadomska, Grażyna
Wyrzykowska, Jolanta
Chechłacz, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1044354.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cholinergic neurons morphology and phenotype
aging
nerve growth factor
plasticity
basal forebrain
Opis:
The trophic effect of continuous intraventricular infusion of nerve growth factor (NGF) on morphology of the basal forebrain (BF) cholinergic neurons was tested in 4- and 28-month-old male Wistar rats. All studies were conducted using behaviorally uncharacterized animals from the same breeding colony. Immunohistochemical procedure for choline acetyltransferase (ChAT) and p75NTR receptor has been applied to identify cholinergic cells in the structures of basal forebrain (BF). Using a quantitative image analyzer, morphometric and densitometric parameters of ChAT- and p75NTR-positive cells were measured immediately after cessation of NGF infusion. In 28-month-old non-treated rats the number of intensively ChAT-positive cells in all forebrain structures was reduced by 50-70% as compared with young animals. The remaining ChAT-positive cells appeared shrunken and the neuropil staining was markedly reduced. In contrast, the same neurons when stained for p75NTR were numerous and distinctly visible with perfect morphology. Analysis of Nissl stained sections also showed that 28-month-old rats did not display significant losses of neuronal cell bodies. NGF restored the number of intensely stained ChAT-positive cells to about 90% of that for young controls and caused a significant increase in size of those cells in 28-month-old rats as compared with the control, age-matched group. NGF did not influence the morphology of p75NTR-positive neurons, which were well labeled, irrespective of treatment and age of the rats. In 4-month-old rats, NGF infusion decreased the intensity of both ChAT and p75NTR immunostaining. These data provide some evidence for preservation of BF cholinergic neurons from atrophy during aging and indicate that senile impairment of the cholinergic system in rats concerns decrease in ChAT-protein expression rather than an acute degeneration of neuronal cell bodies. Treatment with NGF resulted in restoration of cholinergic phenotype in the BF neurons of aged rats. However, the present study also rises issue of possible detrimental effects of NGF in young normal animals.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 313-330
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of aging on UVC-induced apoptosis of rat splenocytes.
Autorzy:
Radziszewska, Ewa
Piwocka, Katarzyna
Bielak-Żmijewska, Anna
Skierski, Janusz
Sikora, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1044357.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
transcription factors
apoptosis
splenocytes
Opis:
UVC-induced apoptotic symptoms such as morphological changes, DNA fragmentation, Bcl-2 and Bax protein expression were examined in primary splenocyte cultures from young (3 months) and old (24 months) rats. The activities of AP-1 and CRE transcription factors in UVC-irradiated splenocytes were also assessed. At 24 h after UVC irradiation 40% of cells derived from young rats were found to be apoptotic, which was twice as much as in splenocytes from old rats. Apoptosis in cells from old rats did not give typical symptoms like a "DNA ladder" and Bcl-2 protein downregulation, in contrast to splenocytes from young rats. No AP-1 transcription factor activity was found in UVC-irradiated splenocytes from old animals and only a trace activity in splenocytes from young animals. This indicates that, UVC-induced apoptosis in rat splenocytes is practically AP-1 independent and that cells from old rats are less sensitive to UVC irradiation than splenocytes from young rats.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 339-347
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.
Autorzy:
Strosznajder, Joanna
Jęśko, Henryk
Strosznajder, Robert
Powiązania:
https://bibliotekanauki.pl/articles/1044342.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
amyloid
poly(ADP-ribose) polymerase
hippocampus
neurotoxicity
Opis:
It is suggested that the fibrillar amyloid beta peptide (Aβ) in brain plays a direct role in neurodegeneration in Alzheimer's disease, probably through activation of reactive oxygen species formation. Free radicals and numerous neurotoxins elicit DNA damage that subsequently activates poly(ADP-ribose) polymerase (PARP, EC 2.4.2.30). In this study the effect of neurotoxic fragment (25-35) of full length Aβ peptide on PARP activity in adult and aged rat hippocampus was investigated. In adult (4 month old) rat hippocampus the Aβ 25-35 peptide significantly enhanced PARP activity by about 80% but had no effect on PARP activity in cerebral cortex and in hippocampus from aged (24-27 month old) rats. The effect of Aβ peptide was reduced by half by the nitric oxide synthase inhibitor N-nitro-L-arginine. Stimulation of glutamate receptor(s) itself enhanced PARP activity by about 80% in adult hippocampus. However, Aβ 25-35 did not exert any additional stimulatory effect. These results indicate that Aβ, through NO and probably other free radicals, induces activation of DNA bound PARP activity exclusively in adult but not in aged hippocampus.
Źródło:
Acta Biochimica Polonica; 2000, 47, 3; 847-854
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of stress on the life span of the yeast Saccharomyces cerevisiae.
Autorzy:
Święciło, Agata
Krawiec, Zdzisława
Wawryn, Jarosław
Bartosz, Grzegorz
Biliński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1044359.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
osmotic stress
superoxide dismutase
catalase
Saccharomyces cerevisiae
heat shock
oxidative stress
Opis:
A correlation is known to exist in yeast and other organisms between the cellular resistance to stress and the life span. The aim of this study was to examine whether stress treatment does affect the generative life span of yeast cells. Both heat shock (38°C, 30 min) and osmotic stress (0.3 M NaCl, 1 h) applied cyclically were found to increase the mean and maximum life span of Saccharomyces cerevisiae. Both effects were more pronounced in superoxide dismutase-deficient yeast strains (up to 50% prolongation of mean life span and up to 30% prolongation of maximum life span) than in their wild-type counterparts. These data point to the importance of the antioxidant barrier in the stress-induced prolongation of yeast life span.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 355-364
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effects of galactosamine on UTP levels in the livers of young, adult and old rats.
Autorzy:
Kmieć, Zbigniew
Smoleński, Ryszard
Zych, Marek
Myśliwski, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1044358.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
liver
UTP
rat aging
galactosamine
nucleotides
Opis:
Galactosamine (GalN), a well-known hepatotoxin that depletes the cellular pool of uracil nucleotides, was previously shown to have greater impact on the inhibition of protein synthesis in hepatocytes of old rats as compared with young animals (Kmieć 1994, Ann. N.Y. Ac. Sci. 717, 216-225). In the present study we compared the effects of GalN on the nucleotide content (measured by ion-exchange HPLC) in the livers of young (4 months), adult (12 months), and old (24-26 months old) rats two hours after its intraperitoneal administration. UTP content of the livers of old control rats was significantly lower (by 28%) than that of young animals. GalN administration decreased the UTP content in the livers of young, adult and old rats by, respectively, 55%, 65% and 89%, and increased the content of UDP-sugars by 189%, 175% and 305%. The hepatic content of ATP, ADP, AMP, NAD, GTP except CTP did not differ significantly among the age groups of rats studied, and was not changed by GalN treatment. The content of CTP was significantly higher in old rats (P < 0.03) upon GalN treatment. The lower hepatic content of UTP may partially explain the increased sensitivity of hepatocytes and livers of old rats to the action of galactosamine, and possibly to other hepatotoxic compounds that decrease transcription in the liver.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 349-353
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A Prescriptive Exercise Program for Health Maintenance
Autorzy:
Yamashita, A.
Kawakami, M.
Inagaki, Y.
Ohkubo, T.
Powiązania:
https://bibliotekanauki.pl/articles/89896.pdf
Data publikacji:
2001
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
health maintenance
prescriptive exercise program
aging society
heart rate
relative metabolic rate
myoelectric potential
starsi pracownicy
fizjologia
praca mięśni
wydolność
zdolność fizyczna
metabolizm
Opis:
The aim of this study was to design a prescriptive exercise program for people of various age and fitness basing on the popular in Japan Radio Physical Fitness Exercise, a program based on an experimental approach. The evaluation indices used in the experiment were heart rate (HR), oxygen consumption, and electrical activity of the rectus femoris, latissimus dorsi, and trapezius muscles, which measured during various motion elements of the program performed at various rate. The results of this study enable to calculate equations for predicting HR during exercise from relative metabolic rate (RMR). The data on HR, RMR, and myoelectric potential presented in this study may be a basis for designing individual exercise programs for elderly people.
Źródło:
International Journal of Occupational Safety and Ergonomics; 2001, 7, 2; 195-209
1080-3548
Pojawia się w:
International Journal of Occupational Safety and Ergonomics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human mitochondria in health, disease, ageing and cancer
Autorzy:
Bartnik, E
Lorenc, A.
Mroczek, K.
Powiązania:
https://bibliotekanauki.pl/articles/2041927.pdf
Data publikacji:
2001
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
health
oxidative phosphorylation
disease
genetics
mitochondrion
man
human cell
aging
metabolic process
cancer
Źródło:
Journal of Applied Genetics; 2001, 42, 1; 65-71
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł

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