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Wyszukujesz frazę "age related diseases" wg kryterium: Temat


Wyświetlanie 1-3 z 3
Tytuł:
The rules of aging: are they universal? Is the yeast model relevant for gerontology?
Autorzy:
Bilinski, Tomasz
Zadrag-Tecza, Renata
Powiązania:
https://bibliotekanauki.pl/articles/1039193.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
age related diseases
longevity
yeast
Opis:
The success of experimental biology was possible due to the use of model organisms. It is believed that the mechanisms of aging have a universal character and they are conserved in a wide range of organisms. The explanation of these universal mechanisms by tracing survival curves of model organisms clearly suggests that death of individuals is a direct consequence of aging. Furthermore, the use of unicellular organisms like yeast Saccharomyces cerevisiae to explain the aging processes of multicellular organisms runs the risk of oversimplification. Aging is a very complex process and therefore in this paper we present arguments suggesting that some of these fundamental assumptions require a deep rethinking and verification.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 663-669
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oxidative damage to DNA and antioxidant status in aging and age-related diseases
Autorzy:
Olinski, Ryszard
Siomek, Agnieszka
Rozalski, Rafal
Gackowski, Daniel
Foksinski, Marek
Guz, Jolanta
Dziaman, Tomasz
Szpila, Anna
Tudek, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1041102.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ROS
aging
oxidative DNA damage
age-related diseases
BER
GO system
Opis:
Aging is a complex process involving morphologic and biochemical changes in single cells and in the whole organism. One of the most popular explanations of how aging occurs at the molecular level is the oxidative stress hypothesis. Oxidative stress leads in many cases to an age-dependent increase in the cellular level of oxidatively modified macromolecules including DNA, and it is this increase which has been linked to various pathological conditions, such as aging, carcinogenesis, neurodegenerative and cardiovascular diseases. It is, however, possible that a number of short-comings associated with gaps in our knowledge may be responsible for the failure to produce definite results when applied to understanding the role of DNA damage in aging and age-related diseases.
Źródło:
Acta Biochimica Polonica; 2007, 54, 1; 11-26
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Work Ability in Ageing Workers Suffering From Chronic Diseases
Autorzy:
Jędryka-Góral, A.
Bugajska, J.
Łastowiecka, E.
Najmiec, A.
Rell-Bakalarska, M.
Bownik, I.
Michalak, J. M.
Kochmański, M.
Powiązania:
https://bibliotekanauki.pl/articles/89939.pdf
Data publikacji:
2006
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
work ability
ageing
age-related diseases
chronic diseases
zdolność do pracy
starsi pracownicy
choroba zawodowa
starzenie się
choroby chroniczne
Opis:
The aim of this study was to investigate the work ability in ageing workers suffering from osteoarthritis (OA), coronary heart disease (CHD) or hypertension (H). One hundred and sixty-six OA and 355 CHD/H outpatients were evaluated. The Work Ability Index (WAI) served for work ability assessment. Patients’ results were compared with the results of a control group of 225 healthy young workers. Statistical analysis was performed with ANOVA tests. WAI in female and male CHD/H patients was higher than in OA patients (p < .01), better work ability was related to better education (p < .01), white-collar work (p < .01) and better recreation (p < .01); subjective work ability was determined mostly by the objective health status. The promotion of work ability among workers suffering from advanced age-related diseases should be closely related to the promotion of health. It is indicative to improve occupational education and skills, already at an early stage of a disease.
Źródło:
International Journal of Occupational Safety and Ergonomics; 2006, 12, 1; 17-30
1080-3548
Pojawia się w:
International Journal of Occupational Safety and Ergonomics
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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