- Tytuł:
- Current approaches to disentagle the mystery of knotted protein folding
- Autorzy:
-
Dabrowski-Tumanski, P.
Sklodowski, M.
Sulkowska, J. I. - Powiązania:
- https://bibliotekanauki.pl/articles/1938626.pdf
- Data publikacji:
- 2016
- Wydawca:
- Politechnika Gdańska
- Tematy:
-
knotted proteins
minimal contact map
YibK - Opis:
- The folding of knotted proteins remains a mystery both for theoreticians and experimentalists. Despite the development of new models, the driving force for self-tying remains elusive and the principle of minimal frustration cannot be reproduced in silico. In this paper we review different models used to understand protein self-knotting and suggest, how to improve the structure based model to observe efficient folding. Our preliminary results show, that including information about some amino acids properties, or reducing the set of physical contacts may be beneficial for modeling of the knotted protein folding.
- Źródło:
-
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2016, 20, 4; 361-372
1428-6394 - Pojawia się w:
- TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
- Dostawca treści:
- Biblioteka Nauki
Artykuł