- Tytuł:
- Assessment of substituent effects and antimicrobial activities of some 2ʹ,5ʹ-dimethyl phenyl chalcones
- Autorzy:
-
Joseph, S. J.
Kamalakkannan, D.
Arulkumaran, R.
Sakthinathan, S. P.
Suresh, R.
Sundararajan, R.
Vijayakumar, S.
Ranganathan, K.
Vanangamudi, G.
Thirunarayanan, G. - Powiązania:
- https://bibliotekanauki.pl/articles/412597.pdf
- Data publikacji:
- 2014
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
substituted styryl 2
5ʹ-dimethyl phenyl chalcones
UV spectra
IR spectra
NMR spectra
substituent effects
antimicrobial activities - Opis:
- Some 2ʹ,5ʹ-dimethyl phenyl chalcones have been synthesized by Crossed-Aldol condensation between 2,5-dimethyl acetophenone and various substituted benzaldehydes using catalytic amount of sodium hydroxide and ethanol. The yields of the chalcones are more than 93 %. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.
- Źródło:
-
International Letters of Chemistry, Physics and Astronomy; 2014, 5; 99-123
2299-3843 - Pojawia się w:
- International Letters of Chemistry, Physics and Astronomy
- Dostawca treści:
- Biblioteka Nauki
Artykuł