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Tytuł:
Antiparasitic drug-design strategy as an interdisciplinary process
Autorzy:
Boczon, K.
Powiązania:
https://bibliotekanauki.pl/articles/836476.pdf
Data publikacji:
1994
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Trichinella
Leishmania
drug
Trypanosoma
Protozoa
antiprotozoon drug
phosphoglicerate kinase
antiparasitic drug
Źródło:
Annals of Parasitology; 1994, 40, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antiparasitic drug-design strategy as an interdisciplinary process
Autorzy:
Boczoń, K.
Powiązania:
https://bibliotekanauki.pl/articles/2151472.pdf
Data publikacji:
1994
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Trichinella
Leishmania
drug
Trypanosoma
Protozoa
antiprotozoon drug
phosphoglicerate kinase
antiparasitic drug
Źródło:
Wiadomości Parazytologiczne; 1994, 40, 3; 313-314
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aqueous Extracts of Ginger (Zingiber officinale Roscoe) and Garlic (Allium satium L.) Bulbs: Phytochemical Screening and In vivo Antitrypanosomal Effect
Autorzy:
Adesola, Ridwan Olamilekan
Ogbole, Esther
Itodo, Akogmu Emmanuel
Salami, Oyiza
Abdulazeez, Modinat Dasola
Powiązania:
https://bibliotekanauki.pl/articles/1839427.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Ginger
Garlic
Parasitaemia
Phytochemical screening
Trypanosoma brucei brucei
Opis:
Aims: To evaluate the phytoconstituent and antitrypanosomal effects of aqueous extracts of Ginger and Garlic bulbs in mice experimentally infected with Trypanosoma brucei brucei. Design: A total of 30 adult male mice (weighing 25-40 g) were randomly grouped into six groups (I, II, III, IV, V, and VI) of 5 animals each. Five Groups (II-VI) were intraperitoneally injected with T. brucei brucei (5×105 cells/ml). Methods and Material: Aqueous extract of ginger and garlic bulbs were obtained using the procedure described by Wabo Pone and the extracts were subjected to phytochemical screening using the standard screening method of Silva. Also, each mice was inoculated with 0.1 ml of blood containing approximately 5×105 cells/ml as described by Herbert and Lumsden. Finally, the aqueous extracts were tested on the inoculated mice. Statistical analysis used: Data obtained were expressed as mean ± standard error of the mean (SEM), and subjected to one-way analysis of variance (ANOVA), SPSS 17.0 statistical software. p<0.05 was considered significant. Results: The aqueous extracts increased the survival time, packed cell volume, rectal temperature, and body weight (Ginger extract only) of mice infected with Trypanosoma brucei brucei. Phytochemical analysis revealed alkaloids, steroids, cardiac glycosides, phenol, and saponins in both Ginger and Garlic. Conclusions: Aqueous extracts of Ginger and Garlic bulbs do not have an anti-trypanosomal effect on Trypanosoma brucei brucei. Consequently, geographical location and time of collection of plants are factors that accept therapeutic on ginger and garlic on tryps and should be considered when testing the plants' efficacy on Trypanosoma brucei brucei.
Źródło:
World News of Natural Sciences; 2021, 37; 135-150
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Attempted Transmission of Trypanosoma evansi to Rats and Mice by Direct Ingestion of Contaminated Blood and via Engorged Ticks
Autorzy:
Vergne, Timothée
Kamyinkird, Ketsarin
Desquesnes, Marc
Jittapalapong, Sathaporn
Powiązania:
https://bibliotekanauki.pl/articles/763575.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Trypanosoma evansi, peroral transmission, rats, mice, ticks, Rhipicephalus sanguineus
Opis:
Trypanosoma evansi is a blood parasite principally transmitted by mechanical vectors (tabanids and stable flies) in large animals such as livestock. However, in other types of hosts, such as carnivores and rodents, oral transmission may be more important. In this experiment, attempts were made to infect rats and mice by the peroral route using infected blood, and ticks engorged on infected rats, in order to evaluate the potential role of ticks as passive vectors of trypanosomes. A strain of Trypanosoma evansi isolated from a cow in Thailand was grown in a rat and blood was collected at the peak of parasitaemia. In the first experiment, 5 rats and 5 mice were fed respectively with 1 ml and 0.5 ml of blood containing 107 Trypanosoma evansi/ml. In the second experiment, adult ticks belonging to the species Rhipicephalus sanguineus, which had fed on parasitaemic rats, were given as food to 3 healthy rats. For both experiments, the presence of parasites in the blood of the rats and mice was checked daily for 10 days, then every 2 days for the following 20 days. Within an average of 4.5 days post blood ingestion (from 4 to 5), 80% (CI95% 29–99) of the rats exhibited parasites by direct microscopic examination of the blood. Similarly, with an average of 4.7 days post ingestion (from 4 to 6), 60% (CI95% 15–95) of the mice exhibited blood parasites. After tick ingestion, no parasites were found in the blood of the rats fed with infected engorged ticks. Consequently, in this experiment, as in others, rats and mice appeared to be receptive by the oral route, but the possible role of ticks as a passive vector could not be demonstrated. Other models could be explored, involving the cattle tick (Rhipicephalus (Boophilus) microplus), to investigate the link from large to small animals.
Źródło:
Acta Protozoologica; 2011, 50, 2
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ekologiczne aspekty zarazenia nornicy rudej Clethrionomys glareolus Schreber, 1780] swidrowcem Trypanosoma [Herpetosoma] evotomys Hadven, 1912
Autorzy:
Karbowiak, G
Wita, I.
Powiązania:
https://bibliotekanauki.pl/articles/841003.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
pasozyty zwierzat
aspekty ekologiczne
parazytologia
nornica ruda
inwazja pasozytnicza
swidrowiec
Clethrionomys glareolus
Trypanosoma evotomys
Opis:
The studies were carried out in Kosewo Górne in the Mazurian District (North-East region of Poland), in September 1995, September 1996 and between May 1997 and June 1998 each month. The animals were trapped in live traps, and after study they were marked and released. The infection of trypanosomes was detected using microhaematocrit centrifugation technique and in blood smears. The intensity of infection had the range from 50 to 150000 individuals in 1ml of blood. The maximal prevalence of infection was in August and September and there were 45% and 38% of infected voles respectively. The infection was detected also in May 1998, in other months the prevalence had low level. There were no individuals of bank vole infected in succecding months. The females of bank vole are more often infected with trypanosomes than males.
Źródło:
Annals of Parasitology; 2001, 47, 4; 789-795
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ekologiczne aspekty zarażenia nornicy rudej Clethrionomys glareolus Schreber, 1780] świdrowcem Trypanosoma [Herpetosoma] evotomys Hadven, 1912
ECOLOGICAL ASPECTS OF INFECTION OF BANK VOLE CLETHRIONOMYS GLAREOLUS (SCHREBER, 1780) WITH TRYPANOSOMA (HERPETOSOMA) EVOTOMYS. HADWEN, 1912
Autorzy:
Karbowiak, G.
Wita, I.
Powiązania:
https://bibliotekanauki.pl/articles/2148219.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
pasozyty zwierzat
aspekty ekologiczne
parazytologia
nornica ruda
inwazja pasozytnicza
swidrowiec
Clethrionomys glareolus
Trypanosoma evotomys
Opis:
The studies were carried out in Kosewo Górne in the Mazurian District (North-East region of Poland), in September 1995, September 1996 and between May 1997 and June 1998 each month. The animals were trapped in live traps, and after study they were marked and released. The infection of trypanosomes was detected using microhaematocrit centrifugation technique and in blood smears. The intensity of infection had the range from 50 to 150000 individuals in 1ml of blood. The maximal prevalence of infection was in August and September and there were 45% and 38% of infected voles respectively. The infection was detected also in May 1998, in other months the prevalence had low level. There were no individuals of bank vole infected in succecding months. The females of bank vole are more often infected with trypanosomes than males.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 789-795
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Low seroprevalence of Trypanosoma cruzi infection and chronic chagasic cardiomyopathy in a region with abundance of triatomine vectors in Yucatan Peninsula of Mexico
Autorzy:
Monteon, V.
Solis-Oviedo, R.
Lopez, R.
Hernandez, O.
Tellez, C.A.
Powiązania:
https://bibliotekanauki.pl/articles/5865.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
seroprevalence
Trypanosoma cruzi
parasitic infection
chronic Chagas cardiomyopathy
Chagas disease
triatomine vector
Yucatan Peninsula
Mexico
Opis:
The Yucatan Peninsula of Mexico is endemic with Chagas disease. The main vector responsible for Trypanosoma cruzi transmission is Triatoma dimidiata which is abundant in domestic, peridomestic and sylvan cycles. The abundance of vectors favours T. cruzi transmission and is a high risk for developing chronic chagasic cardiomyopathy (CCC). In the past 10 years, little information was available on parasite seroprevalence and the prevalence of CCC in the Yucatan Peninsula. In the present work, we studied two Mayan communities with a high abundance of T. dimidiata and a random serial sample of 233 patients with an altered electrocardiogram or cardiac failure admitted to the Regional Hospital. A homemade enzyme-linked immunosorbent assay and indirect immunofluorescence standardized techniques were used to detect anti-T. cruzi IgG. In addition, Mayan volunteers were monitored by electrocardiography. In the Mayan communities, 4.8% (3/63) subjects were positive for T. cruzi antibodies none of them presented electrocardiographic alterations, however in seronegative subjects were detected right or left ventricle hypertrophy in 25% (16/63). A remarkable finding was that 90% of the Mayan population recognized the vector and 65% of them had experienced contact with triatomines bites. At the Regional Hospital 0.42% (1/233) were positive for T. cruzi antibodies showing compatible diagnosis with CCC; the most frequent pathology in this population was hypertension in 65% (151/233) and the less frequent was dilated myocardiopathy 6% (14/233). In conclusion, the prevalence of T. cruzi infection and CCC can be considered low in Yucatan, Mexico.
Źródło:
Annals of Parasitology; 2015, 61, 4
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przegląd współczesnych zagadnień protoparazytologicznych
A review of current problems in protoparasitology
Autorzy:
Kazubski, S.L.
Powiązania:
https://bibliotekanauki.pl/articles/839893.pdf
Data publikacji:
1988
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia
pasozyty
pierwotniaki
Protozoa
Trypanosoma
Cryptosporidium
Pneumocystis
Pneumocystis carinii
Myxosporidia
Microsporidia
problemy badawcze
badania parazytologiczne
Opis:
On the basis of literature data a review is given of some current problems associated with protozoan parasites. These are: occurrence of sexual process in trypanosomes, biology and taxonomy of Cryptosporidium with remarks on the grounds of coccidian system, incidence and life cycle of Pneumocystis carinii, new findings in the biology of Myxosporidia, the problem of Myxosoma cerebralis - Triactinomyxon, the phenomenon of endogeny in the development of myxosporidian plasmodia, alternative ways in the life cycle of Microsporidia. Changes in the "great systematics" of Protozoa - formation of the kingdom Protista and its implications for protoparasitology are also considered.
Źródło:
Annals of Parasitology; 1988, 34, 4-6
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przegląd współczesnych zagadnień protoparazytologicznych
A review of current problems in protoparasitology
Autorzy:
Kazubski, S.L.
Powiązania:
https://bibliotekanauki.pl/articles/2152666.pdf
Data publikacji:
1988
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia
pasozyty
pierwotniaki
Protozoa
Trypanosoma
Cryptosporidium
Pneumocystis
Pneumocystis carinii
Myxosporidia
Microsporidia
problemy badawcze
badania parazytologiczne
Opis:
On the basis of literature data a review is given of some current problems associated with protozoan parasites. These are: occurrence of sexual process in trypanosomes, biology and taxonomy of Cryptosporidium with remarks on the grounds of coccidian system, incidence and life cycle of Pneumocystis carinii, new findings in the biology of Myxosporidia, the problem of Myxosoma cerebralis - Triactinomyxon, the phenomenon of endogeny in the development of myxosporidian plasmodia, alternative ways in the life cycle of Microsporidia. Changes in the "great systematics" of Protozoa - formation of the kingdom Protista and its implications for protoparasitology are also considered.
Źródło:
Wiadomości Parazytologiczne; 1988, 34, 4-6; 450-458
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przypadki zarażenia szczurów wędrownych Rattus norvegicus [Berkenhout, 1769] świdrowcem Trypanosoma lewisi [Kent, 1880] Laveran i Mesnil, 1901, na terenie aglomeracji warszawskiej
THE CASES OF INFECTION OF BROWN RATS RA7TUS NORVEGICUS WITH TRYPANOSOMA LEWISI (KENT, 1880) LAVERAN I MESNIL, 1901, IN THE AREA OF WARSAW AGGLOMERATION
Autorzy:
Karbowiak, G.
Wita, I.
Powiązania:
https://bibliotekanauki.pl/articles/2147966.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
tereny miejskie
szczur wedrowny
parazytologia
Rattus norvegicus
pasozyty
inwazja pasozytnicza
swidrowiec
Warszawa
aglomeracje miejskie
Trypanosoma lewisi
Opis:
Two from three brown rats (Rattus norvegicus) catched in Milanówek near Warsaw, and one catched in the centre of Warsaw were infected with Trypanosoma lewisi. The morphometric features of trypanosomes were in accordance with the features of T. lewisi gived by other authors. This is first note about infection of free living rats with T. lewisi in Poland.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 3; 377-382
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przypadki zarazenia szczurow wedrownych Rattus norvegicus [Berkenhout, 1769] swidrowcem Trypanosoma lewisi [Kent, 1880] Laveran i Mesnil, 1901, na terenie aglomeracji warszawskiej
Autorzy:
Karbowiak, G
Wita, I.
Powiązania:
https://bibliotekanauki.pl/articles/839633.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
tereny miejskie
szczur wedrowny
parazytologia
Rattus norvegicus
pasozyty
inwazja pasozytnicza
swidrowiec
Warszawa
aglomeracje miejskie
Trypanosoma lewisi
Opis:
Two from three brown rats (Rattus norvegicus) catched in Milanówek near Warsaw, and one catched in the centre of Warsaw were infected with Trypanosoma lewisi. The morphometric features of trypanosomes were in accordance with the features of T. lewisi gived by other authors. This is first note about infection of free living rats with T. lewisi in Poland.
Źródło:
Annals of Parasitology; 2001, 47, 3; 377-382
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rola dopełniacza w odporności na zakażenia pierwotniakami
Autorzy:
Jankowski, S.
Powiązania:
https://bibliotekanauki.pl/articles/2148914.pdf
Data publikacji:
1997
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Naegleria fowleri
dopelniacze
odpornosc organizmow
bialko C
swidrowce
Toxoplasma gondii
mechanizmy obronne
Leishmania
opornosc na pasozyty
parazytologia
pierwotniaki
inwazja pasozytnicza
Trypanosoma cruzi
Entamoeba histolytica
Opis:
The scope of this work is the presentation of new theories concerning the role of complement (C) in the resistance of high organism to the infection caused by protozoa. The mechanisms protecting of Entamoeba histolytica, Leishmania spp., Trypanosoma cruzi, Toxoplasma gondii and Naegleria fowleri from the action of C are also described.
Źródło:
Wiadomości Parazytologiczne; 1997, 43, 4; 369-383
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rola dopelniacza w odpornosci na zakazenia pierwotniakami
Autorzy:
Jankowski, S
Powiązania:
https://bibliotekanauki.pl/articles/837137.pdf
Data publikacji:
1997
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Naegleria fowleri
dopelniacze
odpornosc organizmow
bialko C
swidrowce
Toxoplasma gondii
mechanizmy obronne
Leishmania
opornosc na pasozyty
parazytologia
pierwotniaki
inwazja pasozytnicza
Trypanosoma cruzi
Entamoeba histolytica
Opis:
The scope of this work is the presentation of new theories concerning the role of complement (C) in the resistance of high organism to the infection caused by protozoa. The mechanisms protecting of Entamoeba histolytica, Leishmania spp., Trypanosoma cruzi, Toxoplasma gondii and Naegleria fowleri from the action of C are also described.
Źródło:
Annals of Parasitology; 1997, 43, 4; 369-383
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selected host response reactions to fungal or parasite invasion
Autorzy:
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/840577.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
response reaction
parasite invasion
Trypanosoma
fungi
fungal invasion
Toxoplasma
Plasmodium
host
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selenocysteine in Trypanosoma evansi: Identification of the Genes selb, selc, seld, pstk, seltryp and the Selenophosphate Synthetase Protein
Autorzy:
Tavares, Kaio Cesar Simiano
Dambrós, Maria Gabriela Casagrande
Antunes, André Saraiva Leão
Danziato, Pietro Martin
Stoco, Patricia Hermes
Schlindwein, Aline Daiane
Moreira, Renato Simões
Miletti, Luiz Claudio
Powiązania:
https://bibliotekanauki.pl/articles/2041954.pdf
Data publikacji:
2021-08-05
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Trypanosoma evansi
selenocysteine
selB
selC
selD
PSTK
seltTRYP
Opis:
Selenoproteins have been described in all three domains of life and their function has been mainly associated with oxidative stress defense. Canonical elements required for selenoprotein production have been identified in members of the kinetoplastid group supporting the existence of a complete selenocysteine synthesis pathway in these organisms. Currently, nothing is known regarding the selenocysteine pathway in Trypanosoma evansi. In this study, we identified the expression of the elements selB, selC, selD, PSTK and selTRYP at the mRNA level in T. evansi. All translated proteins (selD, PSTK, selTRYP and selB) have the domains predicted and higher identity with Trypanosoma brucei. gambiense. The selenophosphate synthetase protein was localized in the cytoplasm. Our results support the existence of an active selenocysteine pathway in T. evansi.
Źródło:
Acta Protozoologica; 2021, 60; 21-29
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
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