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Wyszukujesz frazę "Parasitaemia" wg kryterium: Temat

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    Wyświetlanie 1-2 z 2
    Tytuł:
    Aqueous Extracts of Ginger (Zingiber officinale Roscoe) and Garlic (Allium satium L.) Bulbs: Phytochemical Screening and In vivo Antitrypanosomal Effect
    Autorzy:
    Adesola, Ridwan Olamilekan
    Ogbole, Esther
    Itodo, Akogmu Emmanuel
    Salami, Oyiza
    Abdulazeez, Modinat Dasola
    Powiązania:
    https://bibliotekanauki.pl/articles/1839427.pdf
    Data publikacji:
    2021
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Ginger
    Garlic
    Parasitaemia
    Phytochemical screening
    Trypanosoma brucei brucei
    Opis:
    Aims: To evaluate the phytoconstituent and antitrypanosomal effects of aqueous extracts of Ginger and Garlic bulbs in mice experimentally infected with Trypanosoma brucei brucei. Design: A total of 30 adult male mice (weighing 25-40 g) were randomly grouped into six groups (I, II, III, IV, V, and VI) of 5 animals each. Five Groups (II-VI) were intraperitoneally injected with T. brucei brucei (5×105 cells/ml). Methods and Material: Aqueous extract of ginger and garlic bulbs were obtained using the procedure described by Wabo Pone and the extracts were subjected to phytochemical screening using the standard screening method of Silva. Also, each mice was inoculated with 0.1 ml of blood containing approximately 5×105 cells/ml as described by Herbert and Lumsden. Finally, the aqueous extracts were tested on the inoculated mice. Statistical analysis used: Data obtained were expressed as mean ± standard error of the mean (SEM), and subjected to one-way analysis of variance (ANOVA), SPSS 17.0 statistical software. p<0.05 was considered significant. Results: The aqueous extracts increased the survival time, packed cell volume, rectal temperature, and body weight (Ginger extract only) of mice infected with Trypanosoma brucei brucei. Phytochemical analysis revealed alkaloids, steroids, cardiac glycosides, phenol, and saponins in both Ginger and Garlic. Conclusions: Aqueous extracts of Ginger and Garlic bulbs do not have an anti-trypanosomal effect on Trypanosoma brucei brucei. Consequently, geographical location and time of collection of plants are factors that accept therapeutic on ginger and garlic on tryps and should be considered when testing the plants' efficacy on Trypanosoma brucei brucei.
    Źródło:
    World News of Natural Sciences; 2021, 37; 135-150
    2543-5426
    Pojawia się w:
    World News of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Efficacy of Rectal Artesunate on Parasitaemia and Febrile Condition of Children of Ogun State, South-Western Nigeria
    Autorzy:
    Agbeyangi, O. A.
    Sam-Wobo, S. O.
    Ekpo, U. F.
    Akinloye, O. A.
    Mafiana, C. F.
    Powiązania:
    https://bibliotekanauki.pl/articles/1179244.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Children
    Efficacy
    Febrile Condition
    Malaria
    Ogun State
    Parasitaemia
    Pre-Referral
    Rectal Artesunates
    South-Western Nigeria
    Opis:
    Efficacy of Rectal Artesunate on parasitaemia and febrile condition of children was assessed in 905 children below the age of 5 years. Grid systematic method was employed in selecting sixteen study centres from 8 Local Government Areas of Ogun State. Ethical approvals were obtained in addition to interactive sessions with parents of the children and PHCs medical practitioners. Body weight and temperature were taken and drug was administered at a dose of 5 to 10mg/kg of the body weight per rectum at 0 hour, 24 hours and 48 hours. Efficacy of treatment was monitored by analysing blood samples taken at 0 hour, 24 hours and 48 hours for Malaria Parasites Count (MPC/µl), parasitized red blood cells (PRBC). Data obtained were analyzed using SPSS version 20 to assess association with p-value of < 0.05. A significant (p < 0.05) difference was observed between malaria parasites prevalence at 0 hour, 24 hours and 48 hours. Also a baseline mean malaria parasite density (MPC/µl) of 3,320/μl was observed at 0 hour and a reduction in mean MPC/µl of 1,230/μl and 420/μl at 24 hours and 48 hours respectively with a significant (p < 0.05) difference between MPC/µl at 0 hour, 24 hours and 48 hours. Baseline mean parasitized red blood cells (PRBC) of 4.2 % was observed at 0 hour with reduction in mean PRBC of 2.4 % and 1.1 % at 24 and 48 hours respectively with a significant (p < 0.05) difference between PRBC at 0 hour, 24 hours and 48 hours. Fever Subsidence Ratio between 0 hour, 24 hours and 48 hours were 1.4:1.1. Rectal artesunate is highly effective and well tolerated antimalarial suppository for pre-referral and parenteral therapy.
    Źródło:
    World Scientific News; 2017, 80; 116-142
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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