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    Wyświetlanie 1-5 z 5
    Tytuł:
    Early diagnosis and treatment of invasive aspergillosis as a main determinant of outcome - review of literature according to the presented case report
    Autorzy:
    Borys, Michał
    Piwowarczyk, Paweł
    Sysiak, Justyna
    Czuczwar, Mirosław
    Prystupa, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/988920.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    immunodeficiency
    invasive aspergillois
    icu
    galactomannan
    voriconazole
    Opis:
    Although. Aspergillus spp infection is not the major cause of morbidity in Intensive Care Units (ICUs), mortality among patients treated for it is tremendous. Moreover, invasive aspergillosis (IA) is an independent risk factor of hospital costs and length of stay. The prevalence of this disease is inversely correlated with the immunocompetence of individuals; for instance, the incidence of IA among patients with leukemia is estimated as high as 12.7%. Although there is a significant improvement in the antifungal armamentarium, the appropriate treatment is still being given too late, mostly because of late diagnosis. As well as the diagnosis, the criteria for recognition of IA constitute a challenge. Objective. The aim of this review, based on a case report, is to introduce the problem of poor diagnosis and treatment of IA, especially in the critical care settings. The presented scenario is an example which assists in showing the evidence-based medicine (EBM) approach to the treatment of fungal infections. Furthermore, to demonstrate the appropriate approach to diagnosis and treatment of invasive aspergillosis, the guidelines of The European Organization for Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG) are presented. Conclusions. According to presented literature, Galactomannan assay enables early diagnosis and remains a specific and sensitive tool to diagnose Asppergillosis, both in serum and BAL fluid. The guidelines recommend voriconazole as a first line treatment in IA. Failure to detect and implement proper antifungal treatment may lead to fatal consequences, as in the presented case.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Stabilizacja glikemii u pacjentów OIOM przy użyciu regulatora LQ
    Stabilization KU patient glycaemia with LQ controller
    Autorzy:
    Bauer, W.
    Płuciennik, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/276170.pdf
    Data publikacji:
    2011
    Wydawca:
    Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów
    Tematy:
    OIOM
    glikemia
    regulator LQR
    Python
    symulacja
    ICU
    ICU-MM
    simulation
    blood level of glucose
    LQ controller
    Opis:
    Artykuł poświęcony jest rozważaniom na temat sposobu automatycznej regulacji poziomu cukru we krwi pacjenta oddziału intensywnej opieki medycznej (OIOM). Opisano w nim model ICU-MM oraz proces projektowania regulatora LQ na podstawie modelu. Omówiono też dwa warianty sterowania systemem (za pomocą insuliny oraz glukozy z insuliną). Na koniec zaprezentowano aplikację wykonaną w języku Python umożliwiającą symulację glikemii pacjenta OIOM.
    This article is devoted to reflection about how to automatically control the blood sugar level of the ICU patient. It will describe ICU-MM model and process of designee LQ controller regulator which is based on this model. Two variants of control will be considered (using insulin and glucose with insulin). Finally an application for ICU blood glucose level patient simulation, implemented within Python environment, will be discussed.
    Źródło:
    Pomiary Automatyka Robotyka; 2011, 15, 4; 76-80
    1427-9126
    Pojawia się w:
    Pomiary Automatyka Robotyka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Applications of Cytosorb in clinical practice
    Autorzy:
    Kutnik, P.
    Borys, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2098563.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Critical care
    ICU
    haemadsorption
    blood purification
    Cytosorb
    Opis:
    Introduction and objective. Cytososorb is haemadsorption device approved in the European Union in 2011 for cytokine adsorption. Recently, in 2018, new indications for the device use have been added, including bilirubin and myoglobin removal. This study aimed to present the results of studies pertaining to Cytosorb use in clinical practice. In subsequent sections of this review, indications for Cytosorb therapy and clinical relevance of presented evidence are listed. State of knowledge. In clinical practice, Cytosorb has been reported as one of potential supportive therapies in patients with septic shock. There is evidence of significant reduction of interleukin 6 and vasopressors when Cytosorb is implemented. However, the decreased mortality after Cytosorb has yet to be reported. Besides cytokine adsorption, Cytosorb also collects drugs, a property that can have a beneficial effect on acute drug poisoning (anticoagulants). However, Cytosorb lowers the plasma concentration of some antibiotics which might affect the outcome of patients in septic shock. The haemadsorption device has also been researched in cardiac patients, and some reports suggest a reduced need for vasopressors and blood transfusions when therapy is installed during surgery. Other indications for Cytosorb are also reported, especially the effectiveness in decreasing bilirubin serum concentrations as treatment or bridge therapy, without affecting the albumins. Cytosorb might also be the last resort treatment in acquired haemophagocytic lymphohistiocytosis. Conclusions. The evidence supporting the use of CytoSorb remains elusive. There is lack of large prospective studies which could provide definitive answers about the place of Cytosorb in clinical practice. There are no reports of safety and feasibility issues in all presented studies.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2019, 13, 4; 162-166
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gastro-oesophageal cancer related malnutrition: a challenge case to manage
    Autorzy:
    Elzohry, Alaa Ali M.
    Mohammed, Khalid Fawzy
    Aly, Asmaa Mohamed
    Powiązania:
    https://bibliotekanauki.pl/articles/1062963.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Gastro
    ICU
    SOFA score
    esophageal cancer Hypoalbuminemia
    major cancer surgery
    Opis:
    Gastro-esophageal cancer is a very common malignant tumours arising from the digestive tract. Hypoalbuminemia and weight loss often result from malnourishment. Malnourished patients have a higher incidence of mortality and morbidity causing prolonged hospital stay. To discuss the incidence and effects of Gastro-esophageal cancer related malnutrition and demonstrate different methods to solve this problem. The current review revealed that malnutrition increases the risk of complications and duration of stay in hospital and ICU in GIT cancer patients, as such, accounts for burden on ICU budget.
    Źródło:
    World Scientific News; 2019, 124, 2; 183-192
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Applying Hunger Game Search (HGS) for selecting significant blood indicators for early prediction of ICU COVID-19 severity
    Autorzy:
    Sayed, Safynaz AbdEl-Fattah
    ElKorany, Abeer
    Sayed, Sabah
    Powiązania:
    https://bibliotekanauki.pl/articles/27312915.pdf
    Data publikacji:
    2023
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
    Tematy:
    ICU severity prediction
    COVID-19
    clinical blood tests
    Hunger Game search
    HGS
    optimization algorithm
    support vector machine
    SVM
    feature selection
    Opis:
    This paper introduces an early prognostic model for attempting to predict the severity of patients for ICU admission and detect the most significant features that affect the prediction process using clinical blood data. The proposed model predicts ICU admission for high-severity patients during the first two hours of hospital admission, which would help assist clinicians in decision-making and enable the efficient use of hospital resources. The Hunger Game search (HGS) meta-heuristic algorithm and a support vector machine (SVM) have been integrated to build the proposed prediction model. Furthermore, these have been used for selecting the most informative features from blood test data. Experiments have shown that using HGS for selecting features with the SVM classifier achieved excellent results as compared with four other meta-heuristic algorithms. The model that used the features that were selected by the HGS algorithm accomplished the topmost results (98.6 and 96.5%) for the best and mean accuracy, respectively, as compared to using all of the features that were selected by other popular optimization algorithms.
    Źródło:
    Computer Science; 2023, 24 (1); 113--136
    1508-2806
    2300-7036
    Pojawia się w:
    Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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