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Tytuł:
Factors affecting the course of Graves orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy
Autorzy:
Jagiełło-Korzeniowska, Agnieszka
Sokołowski, Andrzej
Hubalewska-Dydejczyk, Alicja
Romanowska-Dixon, Bożena
Bałdys-Waligórska, Agata
Powiązania:
https://bibliotekanauki.pl/articles/2159024.pdf
Data publikacji:
2022-05-19
Wydawca:
Medical Education
Tematy:
Graves' orbitopathy
Graves' disease
TRAb
NOSPECS
glucocorticoid treatment
orbital radiotherapy
Opis:
Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity. Aim: The aim of our study was to determine the factors affecting the activity and severity of Graves’ orbitopathy, as well as to identify the predictive factors of poor response to glucocorticoid treatment followed by orbital irradiation. Methods: We performed a prospective observational study of 214 patients with Graves’ orbitopathy who were divided into two groups depending on the treatment they had previously obtained for their Graves’ disease. They received i.v. methylprednisolone pulses followed by orbital radiotherapy. They were examined and had their TSH, TRAb and FT4 levels evaluated prior to treatment and after 1, 6 and 12 months. Results: A pre-treatment TRAb concentration higher by one unit (U/L) implied a mean increase in the relative risk of active orbitopathy by 4.7% (p = 0.0362). A TRAb concentration higher by one U/L 1 month after treatment implied a mean increase in the relative risk of moderate-to-severe and severe GO by 8.7% (p = 0.0167) 6 months after treatment. As regards poor response to treatment, patients with moderate-to-severe and severe Graves’ orbitopathy on admission carried a higher risk of being non-responders. Each point scored on the NOSPECS scale prior to treatment increased the relative risk of the patient being a non-responder by 30%. Conclusions: Patients with higher TRAb levels have a higher risk of active Graves’ orbitopathy and moderate-to-severe and severe Graves’ orbitopathy. Monitoring TRAb serum concentration in those patients is of great importance. Patients with more severe Graves’ orbitopathy carry a higher risk of being poor responders to immunosuppressive treatment. Therefore, careful monitoring of patients with Graves’ orbitopathy and their early referral to specialized centers is essential.
Źródło:
OphthaTherapy; 2022, 9, 2; 98-105
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Potrzeba rekonceptualizacji wczesnośredniowiecznych pochówków „wampirów” z ziem polskich
The need of reconceptualization of early medieval burials of ‘vampires’ from Poland
Autorzy:
Dec, Olga
Powiązania:
https://bibliotekanauki.pl/articles/1023719.pdf
Data publikacji:
2020-12-15
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
anti-vampire graves
Western Slavs
vampires
early Middle Ages
atypical graves
Opis:
The aim of the article is to outline the need to reconceptualized the early medieval burials of “vampires” from Poland. These burials are understood as the remains of the so-called “anti- vampire” practices resulting from the social perception of bad death. These, in turn, are recognized as a socio-religious phenomenon, the assumption of which was to postpone the evil actions of the ‘vampire’ by means of certain measures. Due to doubts about the term “vampire”, concerning both the linguistic sphere and the cultural and historical realities, it is suggested not to use it. The proposed alternative, more precise terms would therefore be the terms “returning dead” or “(un)dead”. Another issue raised is the setting of ‘anti-vampire’ burials in an atypical framework. “Anti-vampirical” burials meet the criteria of atypicality on a macro scale, however, it is possible to consider them typical, assuming that they functioned in the culture of Western Slavs in the early Middle Ages as belonging to a specific social group.
Źródło:
Folia Praehistorica Posnaniensia; 2020, 25; 63-70
0239-8524
2450-5846
Pojawia się w:
Folia Praehistorica Posnaniensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antropologia grobów ciałopalnych cmentarzyska Dziekanowice 22
The anthropology of cremation graves in the Dziekanowice 22 grave field
Autorzy:
Wrzesińska, Anna
Wrzesiński, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1887126.pdf
Data publikacji:
2021-11-08
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
Ostrów Lednicki
Dziekanowice site 22
early medieval grave field
skeletal graves
cremation graves
anthropological analysis
Opis:
The article presents the analyses and descriptions of two graves in the Dziekanowice grave field, site 22 (dated back to the late 10th – the late 13th centuries) located on the eastern coast of lake Lednica, approx. 90 m from the eastern bridge leading to Ostrów Lednicki. The isle hosts a hillfort regarded a seat of the then ruler, the sedes regni principales. Within the gord, in the second half of the 10th century, a complex of residential and sacral buildings was raised: a baptistery, a palas and a church. The burial rite as of the late 10th and the early 11th centuries, which appeared in what is now Poland’s territory, is typically associated with Christianity encroaching the area. The issues under discussion, which are not fully explained, include both the ways in which the dead were buried before skeletal burials were introduced and popularised, the methods used to promote the changes, acceptance thereof, the rate and the prevalence of the new mode of burying the dead. In the course of extended excavations in the Dziekanowice 22 grave field, 1,665 graves have been discovered with preserved bone material, among them two graves where cremated bodies were laid (cremation burial). The graves have been dated back to the early Middle Ages (the time of the grave field’s operation).
Źródło:
Slavia Antiqua: rocznik poświęcony starożytnościom słowiańskim; 2021, 62; 171-191
0080-9993
Pojawia się w:
Slavia Antiqua: rocznik poświęcony starożytnościom słowiańskim
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A new Roman Period burial ground of the Przeworsk culture from Pakoszówka (the Upper San River basin)
Autorzy:
Bulas, Jan
Kotowicz, Piotr N.
Okońska, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/2042453.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Carpathians
cremation graves
necropolis
weaponry
Wroczeń Mountain
Opis:
The article concerns the discovery of the new Przeworsk culture burial ground, which is only the second known burial site from the Upper San River basin, beside of necropolis located in Prusiek site 25. The site 33 in Pakoszówka was excavated completely during field works carried out between 2015 - 2018. During the excavations, a number of richly furnished burials were discovered, including extraordinary double warrior grave. Beside of graves where metal parts of weaponry were found, a few graves without rich inventory were discovered. The site is dated to the end of the Early Roman Period and the late Phase C1 of the Younger Roman Period. The burial ground in Pakoszówka corresponds well with the recent funeral finds from Rankovce located in Eastern Slovakia (Košice Region). Together with finds from the Upper Tisa River basin, it indicates migration of the Przeworsk culture population to the areas bordering the Roman Empire in this turbulent time and the special role it played in the events of the end of the second century A.D.
Źródło:
Acta Archaeologica Carpathica; 2019, 54; 91-106
0001-5229
2719-4841
Pojawia się w:
Acta Archaeologica Carpathica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cmentarzysko ludności kultury pucharów lejkowatych w Marianowie, pow. koniński, stan. 17
Autorzy:
Gorczyca, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/1024199.pdf
Data publikacji:
2015-01-01
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
Funnel Beaker culture
cremation
infant graves
Subneolithic
Opis:
The cemetery in Marianowo is the first non-megalithic burial site of the Funnel Beaker culture (hereinafter referred to as TRB from German Trichterbecherkultur), which has been recorded in eastern Wielkopolska. It is also the first one where biritual funeral rites have been adopted. Despite the poor evidence, it might be generally dated to the Classic Wiórek phase (III), and even to sub-phase IIIC of TRB. All six unearthed burials were of children, and the question of the reason why one of them was cremated provides a wide range of interpretative alternatives.
Źródło:
Folia Praehistorica Posnaniensia; 2015, 20; 153-179
0239-8524
2450-5846
Pojawia się w:
Folia Praehistorica Posnaniensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association analysis of vitamin D receptor gene polymorphisms with bone mineral density in young women with Graves disease
Autorzy:
Horst-Sikorska, Wanda
Ignaszak-Szczepaniak, Magdalena
Marcinkowska, Michalina
Kaczmarek, Marta
Stajgis, Malgorzata
Slomski, Ryszard
Powiązania:
https://bibliotekanauki.pl/articles/1040758.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Graves' disease
bone mineral density
VDR polymorphisms
Opis:
Graves' (GD) hyperthyroidism induces accelerated bone turnover that leads to decreased bone mineral density (BMD). The role of the VDR gene in predisposition to primary osteoporosis has been recognized. Recent studies show associations between the VDR gene polymorphisms and susceptibility to autoimmune diseases. Here we analyzed if VDR gene polymorphisms: BsmI, ApaI, TaqI, and FokI may predispose women with Graves' hyperthyroidism to BMD reduction or to disease development. The subjects were 75 premenopausal female Polish patients with GD and 163 healthy women. The genotyping was performed by the use of the restriction fragment length polymorphism analysis (RFLP). We studied the association of the VDR polymorphisms and their haplotypes with patients' BMD and also SNPs and haplotypes association with Graves' disease. We found a strong linkage disequilibrium for the BsmI, ApaI, and TaqI polymorphims that formed three most frequent haplotypes in Graves' women: baT (47.9%), BAt (34.9%), and bAT (16.4%). We did not show statistically significant association of analyzed VDR polymorphisms or haplotypes with decreased bone mineral density in Graves' patients. However, the presence of F allele had a weak tendency to be associated with Graves' disease (with OR=1.93; 95% CI: 0.97-3.84; p=0.058). In conclusion: VDR gene polymorphisms do not predict the risk of decreased BMD in Polish women with Graves'. It may be speculated that the F allele carriers of the VDR-FokI polymorphism are predisposed to Graves' disease development.
Źródło:
Acta Biochimica Polonica; 2008, 55, 2; 371-380
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Persistent hyperthyroidism in a patient after total thyroidectomy: the thyroid anatomy has implications for treatment
Autorzy:
Młodożeniec, Aleksandra
Gala-Błądzińska, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/2038197.pdf
Data publikacji:
2021-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
Grave’s disease
pyramidal lobe
scintigraphy
thyroidectomy
Opis:
Introduction. Grave’s disease (GD) can be treated using three modalities: anti-thyroid medications, radioactive iodine therapy (RAI), or surgery. If surgery is selected, total thyroidectomy is the procedure of choice. Patients with hyperthyroidism frequently have an enlarged thyroid gland, occasionally with a pyramidal lobe. Aim. We point the usefulness of thyroid scintigraphy, which provides valuable information regarding the thyroid anatomy. Description of the case. The manuscript presents a case report of 43-year-old woman with unstable Grave’s disease, who underwent thyroidectomy and developed persistent hyperthyroidism postoperatively. She was referred by an endocrinologist to a nuclear medicine outpatient clinic for RAI therapy. I-iodide scintigraphy revealed two foci with excessive tracer accumulation. One of the foci in the middle of the neck corresponded to the pyramidal lobe. Conclusion. The thyroid anatomy anomalies can lead to unnecessary implications for treatment. Identifying the pyramidal lobe preoperatively and removing it from patients requiring total thyroidectomy may decrease the recurrence rate of hyperthyroidism. Thyroid scintigraphy is a useful diagnostic tool to visualize the pyramidal lobe.
Źródło:
European Journal of Clinical and Experimental Medicine; 2021, 2; 186-188
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical treatment of thyroid orbitopathy
Autorzy:
Zabochnicki, Mateusz
Szaraniec, Wojciech
Pojda-Wilczek, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/24967053.pdf
Data publikacji:
2023-09-30
Wydawca:
Medical Education
Tematy:
thyroid orbitopathy
eye surgery
strabismus
Graves' Disease
Opis:
Thyroid Orbitopathy is manifestation of Grave’s Disease that affects eyes and orbital area. It occurs in the active and inactive phase, during which different signs are presented. When Thyroid Orbitopathy reaches its advanced phase it should be operated, to avoid complications like proptosis or optic nerve neuropathy. Usually, the first choice is orbital fat decompression. However, it is often not enough and bony decompression is necessary. Surgery of the strabismus is also crucial for patient’s quality of life. Its aim is to restore visual field as wide as it is possible. Last step in surgical interventions is eyelid correction to prevent keratopathy and improve esthetic aspects.
Źródło:
OphthaTherapy; 2023, 10, 3; 222-230
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chamber-Like Graves in the West of the Polatsk Principality. Possibilities of Interpretation in the Context of Eastern European Antiquities
Autorzy:
Plavinski, Mikalai
Powiązania:
https://bibliotekanauki.pl/articles/28408478.pdf
Data publikacji:
2022-12-07
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
funeral rite
chamber-like graves
Polatsk Principality
Opis:
The article is devoted to the study of the elite funeral rite of the western regions of the Polatsk Principality at the turn of the 2nd millennium AD. The main attention is paid to the identification of this category of burials with chamber-like graves. The issues of the emergence of a chamber-like funeral ritual in the west of the Polatsk land, the topography and chronology of chamber-like burials, and the origin and social status of the carriers of this tradition are considered.
Źródło:
Światowit; 2021, 60; 33-57
0082-044X
Pojawia się w:
Światowit
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Graves, Crypts and Parthian Weapons excavated from the Gravesites of Vestemin
Autorzy:
KARAMIAN, Gholamreza
FARROKH, Kaveh
KIAPI, Mohammad Fallah
LOJANDI, Hossein Nemati
Powiązania:
https://bibliotekanauki.pl/articles/517687.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach
Tematy:
Parthian Weapons
Vestemin
Iran
Crypts
Graves
military equipment
Opis:
The article describes a series of finds of Parthian military items in the graves and crypts of Vestemin in northern Iran. These findings are especially significant as they provide an array of discoveries of military equipment: swords, daggers, spearheads,arrowheads, armor and a possible helmet. This study obliges a revision of Winkelman’s observation that “few finds of weapons have been made inside Iran” with respect to Parthian military equipment. In an overall sense, these findings may prove to be as significant to the domain of Parthian military studies as the well-known site of Dura Europos. The excavations have also discovered a coin of Philip the Arab or his son from the earlySasanian era which has assisted the authors’ dating of the Vestemin site. The site of Vestemin is not exclusively a burial venue as the site also has defense works as well as a fortress dated the later Parthian era c. 1st century BCE to 3rd century CE).
Źródło:
Historia i Świat; 2018, 7; 35-70
2299-2464
Pojawia się w:
Historia i Świat
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stratyfikacja społeczna ludności prawobrzeżnego leśnostepowego Podnieprza okresu Scytii klasycznej (2. poł. VI–IV/III w. p.n.e.)
Social stratification of forest-steppe population of the right-bank of the Dnieper river during the classical Scythia (the second half of 6th–4th/3rd century BC)
Autorzy:
Burghardt, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/567537.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie
Tematy:
graves
social stratification
forest-steppe
classical Scythia
Scythians
Opis:
The article discusses the issue regarding the reconstruction of social structure of the early Scythian populations from the forest-steppe area of the Dnieper river, in the period between the second half of 6th–4th/3rd century BC, on the basis of funeral materials. As a result of the analysis of the most important elements of burial rites implemented by the discussed population groups, and based on records of ancient authors (The Histories by Herodotus), it has been established that the most valuable sources are the size and complexity of the funerary structure and covering embankment as well as quantitative and qualitative diversity of included inventory. The classification developed on the basis of 198 burials, by means of statistical inference methods, has led to the separation of several classes of graves that can be combined with different social strata. These layers included nomadic higher spheres (leaders of local communities, leaders of “military teams” and tribal aristocracy) and elites of local settled tribes, average members of the population divided into its wealthy representatives and the so-called “simple Scythians” and lower layers of (“the poor”) and people with limited rights (domestic slaves?).
Źródło:
Materiały i Sprawozdania Rzeszowskiego Ośrodka Archeologicznego; 2017, 38; 111-154
0137-5725
Pojawia się w:
Materiały i Sprawozdania Rzeszowskiego Ośrodka Archeologicznego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Early Makuria Research Project: Interim report on the excavation at el-Detti in 2014 and 2015 with Appendix: Metal objects from the el-Detti cemetery
Autorzy:
El-Tayeb, Mahmoud
Czyżewska-Zalewska, Ewa
Kowarska, Zofia
Lenarczyk, Szymon
Powiązania:
https://bibliotekanauki.pl/articles/1707710.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
el-Detti
tumuli
graves
Early Makuria
metal artifacts
Opis:
Burial structures and the assemblages found inside them at the site of el-Detti, about 13 km downstream from Karima and 7 km upstream from el-Zuma, were explored in 2014 and 2015 by a joint team from the Polish Centre of Mediterranean Archaeology University of Warsaw and the National Corporation for Antiquities and Museums of Sudan. The aim was to enable comparison with the excavated burials at el-Zuma, a nearby tumuli field explored by the Early Makuria Research Project in recent years. Special attention was paid to metal artifacts from the tombs (studied in the appendix), which contribute to a better understanding of the local social and cultural traditions. The focus of the Early Makuria Research Project on examining the mortuary customs at el-Detti has helped to identify the burial practices of Early Makurian society and to trace the spread of Early Makurian society over time.
Źródło:
Polish Archaeology in the Mediterranean; 2016, 25; 403-430
1234-5415
Pojawia się w:
Polish Archaeology in the Mediterranean
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Diversity of Weaponry in La Tene Culture Burials in Poland and Comments on the Non-burial Find of a Celtic Sword in Rzeszów
Autorzy:
Kieca, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/2085875.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie
Tematy:
Polska
La Tene Culture
graves
weapon
sword
Rzeszów
Opis:
The purpose of this work is to create a comprehensive summary of arms originating from Celtic warrior graves in Poland. The largest number of artefacts comes from La Tene culture cemeteries from Lower Silesia, in Sobocisko and Głownin. Individual warrior graves came from Podgaj, Smolec and Wiązow. Other examples of weaponry were found in the Kietrz cemetery in Upper Silesia, with Lesser Poland warrior graves from Iwanowice, Aleksandrowice, and Krakow-Witkowice. From Lesser Poland we also know of alleged graves from Krakow-Pleszow and Krakow-Wyciąże. Some comments about the non-burial find of a Celtic sword from Rzeszow will also be given. A fresh consideration of the source material has corrected the earlier interpretation and reinterpreted some aspects. A new detailed chronology will also be proposed. It will also present a very broad area of connections of Celts residing in Poland.
Źródło:
Analecta Archaeologica Ressoviensia; 2021, 16; 73-101
2084-4409
Pojawia się w:
Analecta Archaeologica Ressoviensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Graves disease, celiac disease and liver function abnormalities in a patient - clinical manifestation and diagnostic difficulties
Autorzy:
Góra-Gębka, Magdalena
Woźniak, Małgorzata
Cielecka-Kuszyk, Joanna
Korpal-Szczyrska, Maria
Sznurkowska, Katarzyna
Zagierski, Maciej
Jankowska, Irena
Plata-Nazar, Katarzyna
Kamińska, Barbara
Liberek, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1039288.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
autoimmune disease
Graves' disease
celiac disease
liver abnormalities
children
Opis:
Autoimmune diseases due to probable common pathogenesis tend to coexist in some patients. Complex clinical presentation with diverse timing of particular symptoms and sophisticated treatment with numerous side effects, may cause diagnostic difficulties, especially in children. The paper presents diagnostic difficulties and pitfalls in a child with Graves' disease, celiac disease and liver function abnormalities.
Źródło:
Acta Biochimica Polonica; 2014, 61, 2; 281-284
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Datowanie radiowęglowe grobów komorowych z wczesnośredniowiecznego cmentarzyska w Sowinkach (stan. 23a) w Wielkopolsce
Autorzy:
Krzyszowski, Andrzej
Błaszczyk, Dariusz
Powiązania:
https://bibliotekanauki.pl/articles/1023915.pdf
Data publikacji:
2016-12-15
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
burial archaeology
early medieval cemeteries
chamber graves
radiocarbon dating
Opis:
This paper presents and discusses the results of 14C dating of two chamber graves (no. 148 and 151) from the early medieval cemetery at Sowinki, site 23A (Wielkopolska).
Źródło:
Folia Praehistorica Posnaniensia; 2016, 21; 214-234
0239-8524
2450-5846
Pojawia się w:
Folia Praehistorica Posnaniensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 83

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