- Tytuł:
- Evaluation Of Antioxidant Defense In Patients With Colorectal Carcinoma
- Autorzy:
-
Malinowska, Katarzyna
Mik, Michał
Dziki, Łukasz
Dziki, Adam
Majsterek, Ireneusz - Powiązania:
- https://bibliotekanauki.pl/articles/1395675.pdf
- Data publikacji:
- 2015-07-01
- Wydawca:
- Index Copernicus International
- Tematy:
-
GPx
SOD
colon cancer - Opis:
- Cancers are among the most feared diseases of modern civilization. In Poland, colorectal cancer is one of the tumors with the worst prognosis. The ability to cure is primarily dependent on the stage of the disease at the time of diagnosis. The aim of the study was evaluate antioxidant response in patients with colorectal carcinoma. Material and methods. Twenty patients (14 men and 6 women) aged 61.9± 11.1 years with colorectal cancer were included in the study. Twenty healthy subjects (4 men and 16 women) aged 64 ± 15.3 years formed the control group. The erythrocyte activities of antioxidant enzymes, superoxide dismutase (SOD), and glutathione peroxidase (GPx), Results. A significant increase of GPx, and SOD (p < 0.05) were seen in patients compared to healthy controls. Conclusion. The results indicate that the tested antioxidant enzyme activity of glutathione peroxidase and superoxide dismutase is increased in patients diagnosed with colorectal cancer compared to the control group.
- Źródło:
-
Polish Journal of Surgery; 2015, 87, 7; 357-361
0032-373X
2299-2847 - Pojawia się w:
- Polish Journal of Surgery
- Dostawca treści:
- Biblioteka Nauki