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Tytuł:
Therapeutic potential of flavonoids used in traditional Chinese medicine – a comparative study of galangin, kaempferol, chrysin and fisetin
Potencjał terapeutyczny flawonoidów wykorzystywanych w tradycyjnej medycynie chińskiej – porównanie galanginy, kemferolu, chryzyny i fisetyny
Autorzy:
Sokal, Arkadiusz
Stocerz, Klaudia
Olczyk, Paweł
Kadela-Tomanek, Monika
Powiązania:
https://bibliotekanauki.pl/articles/27320982.pdf
Data publikacji:
2024-02-21
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
flavonoids
chrysin
galangin
kaempferol
fisetin
traditional Chinese medicine
flawonoidy
chryzyna
galangina
kemferol
fisetyna
tradycyjna medycyna chińska
Opis:
One of the branches of traditional Chinese medicine (TCM) is herbal medicine. In this paper, we focus on the biological activity of substances belonging to flavonoids and specific examples of their impact on various body systems. Flavonoids are a group of chemical compounds included in plant materials, honey, propolis or mushrooms used in TCM. Chrysin, galangin, kaempferol and fisetin are examples of flavonoids showing, among others, antioxidant, anti-inflammatory or antibacterial properties, which are the subject of various scientific studies aimed at examining their potential therapeutic effect.
Ziołolecznictwo stanowi jedną z głównych gałęzi tradycyjnej medycyny chińskiej (traditional Chinese medicine – TCM). W pracy skupiono się na aktywności biologicznej wybranych flawonoidów, a także konkretnych przykładach wpływu tych substancji na różne układy organizmu. Flawonoidy to grupa związków chemicznych zawartych w surowcach roślinnych, miodzie, propolisie czy grzybach stosowanych w TCM. Chryzyna, galangina, kemferol i fisetyna to przykłady flawonoidów wykazujących m.in. właściwości przeciwutleniające, przeciwzapalne czy przeciwbakteryjne. Właściwości te są przedmiotem wielu badań naukowych, mających na celu zbadanie ich potencjalnego działania terapeutycznego.
Źródło:
Annales Academiae Medicae Silesiensis; 2024, 78; 49-60
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Controlled drug delivery systems for improved efficacy and bioavailability of flavonoids
Autorzy:
Gopikrishna, A.
Girigoswami, A.
Girigoswami, K.
Powiązania:
https://bibliotekanauki.pl/articles/24200649.pdf
Data publikacji:
2023
Wydawca:
Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
Tematy:
flavonoids
controlled drug delivery system
pH-responsive
electro-responsive
NIR-responsive
flawonoidy
system kontrolowanego uwalniania leku
Opis:
Purpose In past decades, experiments have been done to find the properties of plant polyphenols and their protective role in various diseases. In the present study, a brief review has been done on flavonoids’ protective role in different diseases and controlled drug delivery systems that can be feasible for improving flavonoids’ bioavailability as well as their efficacy in the biological system. Design/methodology/approach Keywords searched in PubMed, and Google Scholar are “Flavones and cardiovascular diseases, flavones and neurodegenerative diseases, isoflavones and neurodegenerative diseases, Flavonoids and ageing, Flavonoids and diseases, total flavonoid content in vegetables, total flavonoid content in fruits, controlled drug delivery system and flavonoids” and the significant recent articles are selected for writing this review. Findings Flavonoids are active components present in plant products that have been found to exert several health benefits, especially in retarding the deleterious effects of CVD, cancer, ageing, diabetes, and neurodegenerative diseases. The different clinical studies have also supported the above notions, and in this commentary, we have highlighted some important findings in the field of flavonoid research. Even though it has various bioactive efficacy, most flavonoids have less bioavailability, requiring controlled drug delivery methods that can also improve flavonoids' bioavailability and stability. pH-, electro-, infrared radiation-, redox- responsive methods of controlled drug release systems are some of the valuable techniques for improving the rate of drug release and bioavailability at the targeted site. Research limitations/implications Research is warranted in this field for improving and developing various materials that can be utilized in the formation of scaffolds/polymers that improves drug loading and controlled drug release properties at the targeted site. Originality/value This review will help the readers to design new strategies in flavonoid research with the help of controlled drug release methods for increased bioavailability and rate of drug release/ controlled drug release.
Źródło:
Journal of Achievements in Materials and Manufacturing Engineering; 2023, 116, 2; 49--60
1734-8412
Pojawia się w:
Journal of Achievements in Materials and Manufacturing Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluating the Total Phenolic, Protein Contents, Antioxidant and Pharmacological Effects of Cynodon dactylon Extracts Against Escherichia coli and Staphylococcus aureus
Autorzy:
Ibrahim, Muhammad
Riaz, Moazama
Ali, Akbar
Shaheen, Musarat
ur Rahman, Shafiq
Aziz, Riffat
Alamri, Abdulhakeem S.
Alhomrani, Majid
Dablool, Anas S.
Alghamdi, Saad
Sameeh, Manal Y.
Tashkandi, Manal A.
Powiązania:
https://bibliotekanauki.pl/articles/27315658.pdf
Data publikacji:
2023
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
Cynodon dactylon
Anti-microbial
Flavonoids
Total Soluble Proteins
Peroxidase
Antioxidant
Super oxide Dismutase
Opis:
The study was aimed to characterize the antioxidant and anti-microbial activities of Cynodon dactylon with special reference on its precise biochemical analysis. Physiological analysis that total carotenoids content (0.3884 ± 0.0172 mg/g), total chlorophyll content (6.1460 ± 0.2915 mg/g), total phenolic contents (13.4703 ± 0.1494 mg/g), chlorophyll a (3.7708 ± 0.1528 mg/g, catalase (CAT) contents (40.2844 ± 0.1515 units/ mg), total anthocyanin contents (5.0166 ± 0.2966 g–1 FW) total soluble proteins (2.9916 ± 0.1734 mg/g) and total flavonoids content (TFC) (4.7863 ± 0.0442 μg/g) was found higher in the leaves of the Cynodon dactylon whereas, chlorophyll b (2.4881 ± 0.1326 mg/g) was found higher in the stem of Cynodon dactylon, while, peroxidase (POD) contents (81.8763 ± 4.6609 units/mg) and superoxidase dismutase (SOD) activity (80.4346 ± 5.9367 units/mg) was investigated higher in roots of Cynodon dactylon. The anti-microbial activity of Cynodon dactylon extracts was performed using a good diffusion technique against two microbial strains. Among all the plant extracts, the methanolic extracts showed a maximum inhibition zone (26.87 mm) against anti-bacterial strain Escherichia coli whereas n-hexane extract showed a maximum inhibition zone (17.88 mm) against anti-fungal strain Candida albicans. This study reported the antimicrobial activity of Cynodon dactylon against some common pathogens such as Staphylococcus aureus, Escherichia coli, and Candida albicans, which are highly associated with nosocomial infection. From the given results it is concluded that Cynodon dactylon could be exploited in pharmacology due to its antioxidant and anti-microbial properties.
Źródło:
Polish Journal of Chemical Technology; 2023, 25, 3; 110--119
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Liofilizowane owoce róży obniżają poziom kortyzolu u studentów po stresie egzaminacyjnym
Freeze-dried rose hips decrease cortisol levels in students after the stress of exams
Autorzy:
Kalemba-Drożdż, Małgorzata
Cierniak, Agnieszka
Grzywacz-Kisielewska, Agata
Powiązania:
https://bibliotekanauki.pl/articles/7453856.pdf
Data publikacji:
2023
Wydawca:
Krakowska Akademia im. Andrzeja Frycza Modrzewskiego
Tematy:
kortyzol
kortyzol w ślinie
stres
owoce róży
Rosa rugosa
stres egzaminacyjny
stresor
polifenole
flawonoidy
antocyjany
cortisol
salivary cortisol
stress
rosehips
examination stress
stressor
polyphenols
flavonoids
anthocyanins
Opis:
Wprowadzenie: Ekstrakty roślinne bogate w polifenole mogą modyfikować poziom stresu. Celem projektu było zbadanie, czy liofilizowane owoce róży (Rosa rugosa) przyjmowane doustnie przez studentów wpływają na poziom kortyzolu przed i po silnie stresującym egzaminie. Materiał i metody: Badanie o charakterze podwójnie ślepej próby objęło zdrowych ochotników rekrutowanych pośród studentów kierunków medycznych. Uczestnicy w grupie badanej przyjmowali kapsułki zawierające po 400 mg liofilizowanych mielonych owoców róży przez pięć kolejnych dni poprzedzających egzamin (stresor). W tym czasie grupa kontrolna przyjmowała placebo. Uczestnicy wypełnili ankietę dotyczącą ich płci, stylu życia, historii chorób, aktywności fizycznej, stosowanej diety, używek, leków i suplementów diety. Próbki śliny do oznaczenia poziomu kortyzolu zostały pobrane trzykrotnie: rano przed rozpoczęciem fazy eksperymentalnej, rano przed stresorem oraz godzinę po ustąpieniu stresora. Poziom kortyzolu w ślinie oznaczono metodą immunoenzymatyczną. Wyniki: Stwierdzono, że przyjmowanie liofilizowanych owoców róży przez pięć dni istotnie zmniejsza poziom kortyzolu u studentów po egzaminie w porównaniu z grupą przyjmującą placebo. Nie wykazano różnic w poziomie kortyzolu przed egzaminem niezależnie od przyjmowanego preparatu. Żaden inny analizowany czynnik nie wpływał na stężenie hormonu stresu u studentów. Wnioski: Liofilizowane owoce róży mogą pomagać w osłabieniu skutków stresu.
Introduction: Plant extracts rich in phenolic compounds may modify the stress level. The aim of this project is to investigate whether freeze-dried rosehips (Rosa rugosa), taken orally by students, affect cortisol concentration before and after a highly stressful exam. Materials and methods: The double-blind study included healthy volunteers recruited from medical and health sciences students. Participants in the study group took capsules containing 400 mg of freeze-dried ground rosehips for five consecutive days preceding the exam (stressor). At that time, the control group was taking a placebo (120 mg of glucose). Participants completed a questionnaire on their gender, lifestyle, medical history, physical activity, diet, stimulants, medications and dietary supplements. Saliva samples for determining the level of cortisol in saliva were taken three times: in the morning before the beginning of the experimental phase, in the morning before the stressor, and one hour after the stressor subsided. The level of cortisol in saliva was determined using ELISA. Results: It was found that taking freeze-dried rosehips for five days significantly reduced the level of cortisol in students after the exam compared to the placebo group. There were no differences in the level of cortisol before the exam, regardless of the preparation taken. No other analyzed factor influenced the concentration of the stress hormone in students. Conclusions: Freeze-dried rosehips can help reduce the effects of stress.
Źródło:
Państwo i Społeczeństwo; 2023, XXIII, 1; 83-97
1643-8299
2451-0858
Pojawia się w:
Państwo i Społeczeństwo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Metabolity wtórne – znaczenie w środowisku przyrodniczym i gospodarce człowieka
Secondary metabolites – importance in the natural environment and human economy
Autorzy:
Nowak, Dorota
Piekutin, Janina
Powiązania:
https://bibliotekanauki.pl/chapters/27317147.pdf
Data publikacji:
2023-07-19
Wydawca:
Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
Tematy:
metabolity wtórne
rośliny
grzyby
flawonoidy
alkaloidy
terpeny
mykotoksyny
biocydy
Trichoderma
secondary metabolites
plants
fungi
flavonoids
alkaloids
terpenes
mycotoxins
biocides
Opis:
Metabolity wtórne to bardzo różnorodna grupa związków chemicznych naturalnie produkowanych przez organizmy. Spełniają one funkcje sygnałów biochemicznych, które umożliwiają komunikację między organizmami. Te niskocząsteczkowe związki organiczne działają jako chemomediatory ekologiczne, pełniąc funkcje obronne, przywabiające, ułatwiające rozmnażania, a także regulacyjne. Metabolity wtórne produkowane są przez bakterie właściwe, promieniowce, grzyby, glony, a także zwierzęta. Poznanie budowy oraz właściwości biologicznych umożliwiło zastosowanie metabolitów wtórnych w produkcji ważnych leków, takich jak: antybiotyki, leki przeciwnowotworowe, przeciwbólowe, immunosupresyjne, obniżające poziom cholesterolu lub regulujące poziom cukru we krwi. Metabolity wtórne mogą być zastosowane także jako naturalne i mniej szkodliwe środki ochrony roślin zwalczające fitopatogeny. Wśród metabolitów wtórnych są również silnie działające związki toksyczne, jak np. mykotoksyny produkowane przez grzyby. W rozdziale dokonano przeglądu literatury na temat budowy, funkcji ekologicznych oraz znaczenia wybranych metabolitów wtórnych roślin oraz grzybów.
Secondary metabolites are a very diverse group of chemical compounds naturally produced by organisms. They perform functions of biochemical signals and enable communication between organisms. They are low-molecular organic compounds and act as ecological chemomediators. They perform defensive, attracting, facilitating reproduction, and regulatory functions. Secondary metabolites are produced by bacteria, actinomycetes, fungi, algae, as well as animals. Knowledge of the structure and biological properties has made it possible to use secondary metabolites in the production of important drugs such as antibiotics, anticancer drugs, painkillers, immunosuppressants, cholesterol-lowering or blood sugar-regulating drugs. Secondary metabolites can also be used as natural and less harmful plant protection products to combat phytopathogens. Among secondary metabolites are also potent toxic compounds such as: mycotoxins produced by fungi. This chapter reviews the literature on the structure, ecological functions and importance of selected secondary metabolites of plants and fungi.
Źródło:
Inżynieria środowiska i biotechnologia. Wyzwania i nowe technologie; 201-214
9788371939013
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chromatographic and mass spectrometric analysis of secondary metabolites of Deschampsia antarctica from Galindez Island, Argentine Islands
Autorzy:
Ivannikov, Roman
Anishchenko, Viktor
Kuzema, Pavlo
Stavinskaya, Oksana
Laguta, Iryna
Poronnik, Oksana
Parnikoza, Ivan
Powiązania:
https://bibliotekanauki.pl/articles/16538469.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
West Antarctic
antarctic hairgrass
polyphenolic antioxidants
flavonoids
luteolin derivatives
Opis:
The aim of this work was to study the polyphenolic composition of Deschampsia antarctica È. Desv. plants grown at natural conditions on different locations on the Galindez Island, Argentine Islands, the maritime Antarctic. The plants were collected during the summer season of the 26th Ukrainian Antarctic Expedition (2020–2022). The extracts of 21 plants were obtained and the composition of the extracts was analyzed by means of high-performance liquid chromatography and matrix-assisted laser desorption/ionization mass spectrometry. The antioxidant properties of the extracts were characterized using the DPPH (2,2-diphenyl-1-picrylhydrazyl) test. The extracts were found to contain large amount of polyphenolic compounds, with flavonoids and phenolic acids, as well as their derivatives, being the most common classes of the phenols. Using the HPLC data the content of various phenols in the plants was systematic studied. It has been found that in all plants the most abundant phenols are flavonoids/flavonoid derivatives (on average about 75% of total mass of phenols). Among the flavonoids, luteolin derivatives predominate (86–94% of the total mass of flavonoids), and, among luteolin derivatives, the main compounds are orientin, orientin 2"- O-β-arabinopyranoside and isoswertiajaponin 2"- O-β-arabinopyranoside (67–83% of the total mass of luteolin derivatives). It has been also found that all the extracts possess the high activity in inhibition of DPPH radicals and that the antioxidant activity of the extracts correlates with total content of phenols in the samples. Thus, Deschampsia antarctica É. Desv. plants are a valuable source of natural phenolic antioxidants, and the most common antioxidants in the extracts are orientin, orientin 2"- O-β-arabinopyranoside and isoswertiajaponin 2"- O-β-arabinopyranoside.
Źródło:
Polish Polar Research; 2022, 43, 4; 341-362
0138-0338
2081-8262
Pojawia się w:
Polish Polar Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plant secondary metabolites as defenses: A review
Autorzy:
Jusuf, Herlina
Elveny, Marischa
Azizova, Feruza
Shichiyakh, Rustem A.
Kulikov, Dmitriy
Al-Taee, Muataz M.
Atiyah, Karrar K.
Jalil, Abduladheem T.
Aravindhan, Surendar
Powiązania:
https://bibliotekanauki.pl/articles/2174280.pdf
Data publikacji:
2022
Wydawca:
Instytut Technologiczno-Przyrodniczy
Tematy:
alkaloids
flavonoids
phenolics
plant pathogens
secondary metabolites
Opis:
Plant secondary metabolites have a variety of functions, including mediating relationships between organisms, responding to environmental challenges, and protecting plants against infections, pests, and herbivores. In a similar way, through controlling plant metabolism, plant microbiomes take part in many of the aforementioned processes indirectly or directly. Researchers have discovered that plants may affect their microbiome by secreting a variety of metabolites, and that the microbiome could likewise affect the metabolome of the host plant. Pesticides are agrochemicals that are employed to safeguard humans and plants from numerous illnesses in urban green zones, public health initiatives, and agricultural fields. The careless use of chemical pesticides is destroying our ecology. As a result, it is necessary to investigate environmentally benign alternatives to pathogen management, such as plant-based metabolites. According to literature, plant metabolites have been shown to have the ability to battle plant pathogens. Phenolics, flavonoids, and alkaloids are a few of the secondary metabolites of plants that have been covered in this study.
Źródło:
Journal of Water and Land Development; 2022, 55; 206--211
1429-7426
2083-4535
Pojawia się w:
Journal of Water and Land Development
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bioaktywne metabolity gryki (Fagopyrum Mill.)
Bioactive matebolites of buckwheat (Fagopyrum Mill.)
Autorzy:
Zawadzka, Agnieszka
Kobus-Cisowska, Joanna
Stachowiak, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/2047813.pdf
Data publikacji:
2021-04-15
Wydawca:
Centrum Doradztwa Rolniczego w Brwinowie. Oddział w Poznaniu
Tematy:
uprawa
gryka
flawonoidy
rutyna
kwercetyna
emodyna
fagopiryna
breeding
buckwheat
flavonoids
rutin
quercetin
emodin
fagopyrin
Opis:
Gryka jest rośliną nie wymagającą specjalnych warunków glebowych i doskonale rośnie w trudnych warunkach środowiskowych, wykazując wysoką odporność na szkodniki i choroby. Gryka zwyczajna (Fagopyrum esculentum Moench) i gryka tatarka (Fagopyrum tataricum (L.) Gaertn.) są bogatym źródłem wielu składników odżywczych oraz związków bioaktywnych, m.in. takich jak rutyna, kwercetyna, emodyna, fagopiryna. Dzięki znaczącym ilościom tych związków gryka została zaliczona do związków, które mogą wpływać na zdrowie. Warunki uprawy odgrywają ważną rolę w kształtowaniu cech nasion gryki.
Buckwheat is a plant that does not require special soil conditions and grows perfectly in harsh environmental conditions, showing high resistance to pests and diseases. Buckwheat (Fagopyrum esculentum) and buckwheat (Fagopyrum tataricum) are rich sources of many nutrients and bioactive compounds, such as rutin, quercetin, emodin, phagopyrin, among others. Thanks to significant amounts of these compounds, buckwheat has been classified as one of the compounds which positively affect health. Growing conditions play an important role in shaping the characteristics of buckwheat seeds.
Źródło:
Zagadnienia Doradztwa Rolniczego; 2021, 103, 1; 58-66
1232-3578
2719-8901
Pojawia się w:
Zagadnienia Doradztwa Rolniczego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chemical composition and antioxidant activity of extracts from Moroccan fresh fava beans pods (Vicia Faba L.).
Autorzy:
Kalili, A.
Ouafi, R.E.
Aboukhalaf, A.
Naciri, K.
Tbatou, M.
Essaih, S.
Belahyan, A.
Belahsen, R.
Powiązania:
https://bibliotekanauki.pl/articles/2082861.pdf
Data publikacji:
2021
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
Vicia faba
chemical composition
antioxidant activity
total phenolics
flavonoids
mineral analysis
Opis:
Background. In Morocco, fava beans are widely used as a main meal or as an ingredient in various traditional recipes, in the form of fresh ripe seeds or dry seeds. In the past, the tender skin of bean pods was also used in certain specific dishes, thus diversifying the diet. However, the peels of the tender bean pods are currently less or not used and considered waste. In Moroccan, fava bean pods peels, traditionally used in food in the past, are today considered as waste. The valorization of fresh fava bean pods could revitalize the use of the specific dishes and diversify the diet. For this reason, the research aimed to assess the nutritional values and biological compounds of the whole fresh fava bean pods (Vicia faba L.). Objective. Evaluate the content of nutrients, total phenolic, flavonoids and tannin contents and antioxidant activity in different extracts of the tender pods of the fava bean (Vicia faba L.). Material and methods. The proximate composition and minerals were determined using AOAC methods. The total phenolic compounds by the Folin-Ciocalteu reagent, the total flavonoids were analyzed using aluminum chloride colorimetric method, the tannins by method of vanillin in an acidic medium and the antioxidant activity was evaluated by DPPH method. Results. The results show that the fresh fava bean pods have a moisture content of 87.31 ± 0.25%, ash 4.67 ± 1.03, and protein 29.11 ± 3.20 g/100 g. The legume samples also contain potassium (1946.8±4.61), phosphorus (483.8 ± 3.14), and calcium (399.6 ±2.25) mg/100 g of dry matter representing at last 40-50% of the RDI. The content of the different extracts of (Vicia faba L) varied from 49.5 to 594.4 mg GAE/ g for the total phenols, from 0.7 mg to 3.4 mg QE/g for flavonoids, and from 4.9 mg to 73.91 mg TAE/g dry weight for tannins. The evaluation of the antioxidant activity in the various extracts revealed a better activity in the methanolic extract (IC50=491.2 μg/mL) compared to others extracts: the MeOH/water extract (IC50=606.61 μg/mL), DCM/ MeOH extract (IC50 = 642.67 μg/mL) and DCM extract below of 50%. Conclusions. This study shows that fava bean pods, traditionally used in food, are rich in macro and micronutrients and bioactive substances, which demonstrates their potential contribution to human food and nutritional security.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2022, 73, 1; 79-86
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of Four-Week Intake of Blackthorn Flower Extract on Mice Tissue Antioxidant Status and Phenolic Content
Autorzy:
Balta, Vedran
Đikić, Domagoj
Crnić, Irena
Odeh, Dyna
Orsolic, Nada
Kmetič, Ivana
Murati, Teuta
Dragović Uzelac, Verica
Landeka Jurčević, Irena
Powiązania:
https://bibliotekanauki.pl/articles/1363304.pdf
Data publikacji:
2021
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
pharmacokinetic
flavan-3-ol
flavonoids
bioavailability
phenolic compounds
Prunus spinosa L
Opis:
The study examined the antioxidative physiological effects of phenolics from an ethanol-water extract of blackthorn flowers orally administrated to C57/BL6 mice for 28 days in daily doses of 25 mg of total phenolics/kg body weight. Contents of phenolics in the intestine, liver, and kidneys collected after 1, 7, 14, 21, and 28 days of extract administration were analyzed by UPLC-MS/MS method. In the same tissues, the antioxidative properties were determined as ferric reducing antioxidant power (FRAP), ABTS•+ scavenging activity, content of reduced glutathione (GSH), and activity of superoxide dismutase (SOD) and catalase (CAT). The lipid peroxidation in tissues was also evaluated by thiobarbituric acid reactive substances (TBARS) assay. The exposed mice (compared to the control ones) had a lower content of TBARS in all tissues mostly on the third/fourth week of daily consumption. SOD activity and GSH content increased on the 28th day in tissues. CAT activity was higher only in the liver after one week of consumption but remained unchanged in other organs throughout the experiment. Phenolic profiles were different in individual tissues. The most prominent increases compared to the control were determined for contents of 3-O-feruloylquinic acid, 4-O-p-coumaroylqiunic acid, kaempferol pentoside, and quercetin rhamnoside in the intestine; for ferulic acid and quercetin 3-O-rutinoside in the liver; and for quercetin 3-O-rutinoside, ferulic acid, and 4-O-p-coumaroylquinic acid in the kidneys. The screened phenolics with different distribution in tissues could be responsible for slight differences in the recorded antioxidative effects.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2020, 70, 4; 361-375
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Elicitation with Sodium Silicate and Iron Chelate Affects the Contents of Phenolic Compounds and Minerals in Buckwheat Sprouts
Autorzy:
Dębski, Henryk
Wiczkowski, Wiesław
Szawara-Nowak, Dorota
Horbowicz, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/1363275.pdf
Data publikacji:
2021
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
Fagopyrum esculentum
common buckwheat
flavonoids
phenolic acids
iron
silicon
Opis:
The study concerned the effect of elicitors on the contents of free flavonoids and phenolic acids, as well as their esters and glycosides, and contents of minerals in 7-day sprouts of common buckwheat. An aqueous solution containing a mixture of sodium silicate and Fe-EDTA (SIL-Fe) was compared with the same concentration of sodium silicate alone (SIL) and water (control). Phenolic compounds were analysed using an HPLC–MS/MS apparatus equipped with an ion-trap mass spectrometer, and analyses were conducted by multiple reaction monitoring of selected negative ions. The contents of macro- and microelements in sprouts were determined by the ICP-AES method, after sample mineralization in a mixture of HNO3 and H2O2. The study showed that SIL-Fe influenced the accumulation of individual phenolics in buckwheat sprouts in different ways. Among the major flavonoids in the buckwheat sprouts treated with SIL-Fe, the content of free forms and esters of (‒)-epicatechin and glycosides of quercetin as well as the total content of flavonoids decreased. Elicitation of buckwheat sprouts with SIL and SIL-Fe reduced the contents of calcium, potassium, copper, and zinc; however, the SIL-Fe treatment caused a 5-fold increase in iron content and a 2-fold increase in silicon content. The ratio of total flavonoids to the iron content of SIL-Fe-treated sprouts was 11.5, which was substantially lower than in the control, where it reached 64. The results of this study indicate that it is possible to produce buckwheat sprouts with a high content of flavonoids and fortified with iron, which may increase the availability of this element.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2021, 71, 1; 21-28
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the phenolic contents and antibacterial activity of different concentrations of Onosma chlorotricum Boiss
Autorzy:
Dousti, B.
Nabipor, F.
Powiązania:
https://bibliotekanauki.pl/articles/2096818.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
phenolic compounds
flavonoids
antibacterial activity
Onosma chlorotricum
Opis:
Because of side effects and increasing resistance to antibiotics, considerable attention hasbeen given to extract sand biologically active compounds isolated from medicinal plants. In the present study, phytochemical screening and antibacterial activities of different concentrations of various extracts of Onosma chlorotricum were evaluated and compared with those of vancomycin and amikacin. Total phenolic and flavonoid contents and the antibacterial activity of methanol, n-hexane, and aqueous extracts (5 mg/ml to 0.156 mg/ml final concentration) of O. chlorotricum against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli were evaluated using disc diffusion and microdilution methods. Total phenolic and flavonoid contents were determined according to the Folin-Ciocalteu and aluminum chloride colorimetric assays, respectively. The results showed that the total phenolic and flavonoid contents of these extracts ranged from 56.10 ± 0.13 to 74.12 ± 0.05 mg GAE/g dry extract and from 19.3 ± 0.6 to 23.20 ± 0.41 mg QE/g dry extract, respectively. The methanol extract with the highest phenolic and flavonoid content showed the highest antibacterial activity against all the tested bacterial strains, with the highest inhibition zone of 21 ± 0.7 mm and the lowest MIC and MBC values of 78.12 μg/ml for S. aureus. The antibacterial effects and the total phenolic content of O. chlorotricum were remarkable. The results suggest that the effects of methanol extract on wound healing could be tested in an animal model.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 4; 377-386
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phenolic and flavonoid contents in Deschampsia antarctica plants growing in nature and cultured in vitro
Autorzy:
Twardovska, Maryana
Konvalyuk, Iryna
Lystvan, Kateryna
Andreev, Igor
Parnikoza, Ivan
Kunakh, Viktor
Powiązania:
https://bibliotekanauki.pl/articles/2041756.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Antarctic
Deschampsia antarctica
in vitro plants
phenolic compounds
flavonoids
HPL Canalysis
Źródło:
Polish Polar Research; 2021, 42, 2; 97-116
0138-0338
2081-8262
Pojawia się w:
Polish Polar Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phenolic Contents and Antioxidant Activity of Extracts of Selected Fresh and Dried Herbal Materials
Autorzy:
Kozłowska, Mariola
Ścibisz, Iwona
Przybył, Jarosław
Ziarno, Małgorzata
Żbikowska, Anna
Majewska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1363258.pdf
Data publikacji:
2021
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
coriander
lovage
tarragon
Indian borage
total phenolics
phenolic acids
flavonoids
Opis:
Total phenolic content (TPC) and phenolic profiles of extracts of the aerial parts of coriander (Coriandrum sativum L.), lovage (Levisticum officinale Koch.), and tarragon (Artemisia dracunculus L.), and leaves of Indian borage (Plectranthus amboinicus) have been investigated. The extracts were prepared using 70% (v/v) ethanol and fresh or air-dried herbal material. Besides phenolic composition, DPPH• and ABTS•+ scavenging activity, and ferric-reducing antioxidant power (FRAP) were determined. The extracts from dried herbal materials exhibited higher TPC and more potent antioxidant activity than those from fresh counterparts. The highest TPC (146.77 g GAE/kg extract) and antioxidant activity (0.491, 0.643, and 0.396 mol TE/kg extract in DPPH, ABTS, and FRAP assays, respectively) were detected for the extract from dried leaves of Indian borage, while the lowest values were determined for the extract from fresh aerial parts of coriander. Five phenolic acids (rosmarinic, chlorogenic, caffeic, ferulic, and neochlorogenic acids) and four flavonoids ((+)-catechin, rutin, hyperoside, and astragalin) were identified in the samples. Only caffeic acid was present in all extracts. Its content in the extracts of dried tarragon and Indian borage was lower than in those of the fresh material. A significant correlation was found between antioxidant activity and the content of phenolic acids. Rutin was found to be the major flavonoid in most extracts. Based on the present study results, the possibility of using the extracts obtained from both fresh and air-dried herbs as potential components for functional food formulation can be considered in the future.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2021, 71, 3; 269-278
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Qualitative and quantitative evaluation of secondary metabolites of different plant extracts of Nothapodytes foetida (Wight) Sleumer an important endangered medicinal tree
Autorzy:
Bai, D. Sunitha
Suvarchala, V.
Pavani, Ch.
Chaithanya, G.
Spoorthi, V.
Shasthree, T.
Powiązania:
https://bibliotekanauki.pl/articles/1839343.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Camptothecin
phytochemicals
alkaloids
flavonoids
glycosides
tannins
phenols
triterpenoids
saponins
Nothapodytes foetida
Opis:
The present study of phytochemical screening has revealed valuable information about the chemical constituents of Nothapodytes foetida. Phytochemical analysis of leaves, stem, bark and root extracts of Nothapodytes foetida was performed using different solvent systems such as chloroform, butanol, hexane, methanol and acetonitrile for the presence of different phytochemicals with standard procedures. The phytochemical screening (both qualitative and quantitative) of variousplant extracts of Nothapodytes foetida revealed the presence of different phytoconstituents such as alkaloids, flavonoids, glycosides, tannins, phenols and triterpenoids. Among all the solvents tested, methanol, butanol and chloroform extract of leaf, stem, bark and root showed high concentration of all phytoconstituents compared to hexane and acetonitrile solvent extracts. The total quantity of secondary metabolites was evaluated by using the standard procedures and the line of regression and the regression coefficient estimated from the calibration curve of various standards. The highest quantity of phytoconstituent present in the plant extracts was identified to be alkaloids. The alkaloid content of leaf was evaluated to be 66.11±0.47, whereas stem possess 56.27±0.38, bark 59.02±0.17 and root 62.34±0.27 mg AE/gm of extracts and subsequent high amounts of phytoconstituents identified was flavonoids, tannins, phenols and saponins. Phytochemical screening of Nothapodytes foetidaused in the medical field for the design of new drugs.
Źródło:
World Scientific News; 2021, 162; 43-59
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 136

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