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Wyszukujesz frazę "FE65" wg kryterium: Temat


Wyświetlanie 1-9 z 9
Tytuł:
Chromatin acetylation, β-amyloid precursor protein and its binding partner FE65 in DNA double strand break repair
Autorzy:
Szumiel, Irena
Foray, Nicolas
Powiązania:
https://bibliotekanauki.pl/articles/1039940.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
chromatin acetylation
FE65
MOF acetyltransferase
DNA double strand break repair
β-amyloid precursor protein
Tip60 histone acetyltransferase
heterochromatin protein 1
Opis:
Among post-translational modifications of chromatin proteins taking place in DNA double strand break (DSB) repair, acetylation plays a prominent role. This review lists several facts and hypotheses concerning this process. Lack of acetyltransferase TIP60 (HIV-Tat interacting protein of 60 kDa) activity results in cells with defective DSB repair. The enzyme is present in the nucleus in a multimeric protein complex. TIP60 dependent activation of ATM (ataxia telangiectasia mutated kinase) is an early event in the response to DNA breakage. Other important acetylations are those of histones H4 and γH2AX. Correct reconstruction of the damaged site is critical for survival and prevention of genetic and epigenetic changes in the cell that may affect the function of its daughter cells. Recently, two proteins with previously unsuspected functions in DSB repair have been identified as active in this process: Alzheimer β-amyloid precursor protein (APP) and its binding partner FE65, β-amyloid precursor binding protein. Their participation in DSB repair in both neuronal and non-neuronal cells is related to acetylation carried out by the acetyltransferase complex. The same function is ascribed to heterochromatin protein 1 (HP1). So far, the relations (if any) between TIP60 activation by HP1 and by the FE65 complex remain unidentified.
Źródło:
Acta Biochimica Polonica; 2011, 58, 1; 11-18
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
SAW Delay Line for Vibration Sensors
Autorzy:
Filipiak, J.
Solarz, L.
Steczko, G.
Powiązania:
https://bibliotekanauki.pl/articles/1417951.pdf
Data publikacji:
2012-11
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
68.35.Iv
Opis:
The paper presents an analysis of surface acoustic wave delay line. The line consists of two simple interdigital transducers placed on a ST-cut quartz plate. Mid-band operation frequency of the line is 74 MHz. The line will be applied for surface acoustic wave vibration sensor. At the immovable end of the plate there are electric signal feeds to both transducers. This is the cause of increase in signal value going directly between the transducers and the cause of line losses. By means of equivalent electric model of interdigital transducer a loss analysis of the line has been made at 50 Ω load. The analysis allows to minimize line losses by matching the transducers to 50 Ω impedance. This has been practically achieved by a design of transducer geometry and configuration matching 50 Ω impedance, by means of inductance. An analysis of repeated operation characteristics of two interdigital transducers has been made. A signal going directly through capacitance between transducers and signals reflected from the edge of piezoelectric substrate have been presented. Results of theoretical analysis have been compared with experimental examinations.
Źródło:
Acta Physica Polonica A; 2012, 122, 5; 808-813
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Transversely Inhomogeneous Nonlinear Surface Ultrasonic Monopulses in Solid Film-Substrate System
Autorzy:
Tecpoyotl-Torres, M.
Vera-Dimas, G.
Grimalsky, V.
Koshevaya, S.
Powiązania:
https://bibliotekanauki.pl/articles/1364175.pdf
Data publikacji:
2014-05
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
42.65.Tg
62.50.Ef
Opis:
Excitation of nonlinear acoustic monopulses, or baseband waves, is theoretically analyzed. The monopulses have a wide spectrum up till the gigahertz range ≤ 1 GHz. The propagation of waves is along the interface between a solid film and a solid substrate. A quadratic elastic nonlinearity in both contacting media of the system is taken into account. The nonlinear dynamics of waves depends essentially on the thickness of the film. The transverse inhomogeneity of the wave profile in the interface plane and the wave diffraction are taken into account, too. The baseband waves are not true solitons and manifest as single shock-like pulses in the case of an excitation from initial long rectangular pulses. The transverse inhomogeneity affects the dynamics of the shocks, and there is a possibility to focus the nonlinear monopulses.
Źródło:
Acta Physica Polonica A; 2014, 125, 5; 1118-1125
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surface Acoustic Wave Vibration Sensor Electronic System
Autorzy:
Filipiak, J.
Solarz, L.
Steczko, G.
Powiązania:
https://bibliotekanauki.pl/articles/1493039.pdf
Data publikacji:
2011-10
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
68.35.Iv
Opis:
The paper presents surface acoustic wave vibration sensor electronic system. The system cooperates with surface acoustic wave delay line. The sensor has been designed for electronic warning systems. The sensor is a four-terminal network. In the system, there is a cascade connection of sensors by means of coaxial cable. Test signal and constant supply voltage are jointly sent between sensors. Separating the signals, their summation and amplification of test signal as well as matching the line to impedance 50 Ω are performed by surface acoustic wave vibration sensor electronic system. The electronic system devices and the making of them are discussed. System development of such a sensor is presented and its design is analysed. Experimental examination results of surface acoustic wave vibration sensor are presented. Parasitic effects occurring in vibration sensor electronic system operation connected with electromagnetic coupling and ground current coupling are discussed.
Źródło:
Acta Physica Polonica A; 2011, 120, 4; 598-603
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of Non-Steady Stage in SAW Gas Sensors with Semiconducting Sensor Layers
Autorzy:
Urbańczyk, M.
Hejczyk, T.
Powiązania:
https://bibliotekanauki.pl/articles/1493326.pdf
Data publikacji:
2011-10
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
07.07.Df
43.25.Fe
68.35.Iv
77.65.Dq
Opis:
The profile of the gas concentration in the sensor layer can be expressed as a polynomial function involving the diffusion coefficient $(D_{K})$, semiconductor film thickness (h), rate constant (k), gas concentration outside the semiconductor film $(C_{S})$. Before reaching a steady state of the concentration profile, its behavior depends on a few factors as the distance from the piezoelectric surface, the rate constant, the thickness of the layer and the diffusion constant and time. We are going to simulate temporary processes in the semiconductor sensor film in the surface acoustic wave gas sensor system and to describe the influence on relative changes of the surface acoustic wave velocity. The numerical results basing on the code written in Pyton, are described and analyzed.
Źródło:
Acta Physica Polonica A; 2011, 120, 4; 789-793
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Numerical Optimization of Structures SAW Gas Sensors
Autorzy:
Hejczyk, T.
Urbańczyk, M.
Powiązania:
https://bibliotekanauki.pl/articles/1399352.pdf
Data publikacji:
2013-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
68.35.Iv
07.07.Df
Opis:
This paper presents the results of the analysis of surface acoustic waves sensor equivalent model. They were the sensor response of the surface acoustic waves sensor in the steady state gas: $H_2$, $CO_2$, $NO_2$, $NH_3$, $C_nH_m$, $CO$. Thin layer of $WO_3$ has been used as a sensor layer. Impedance replacement of sensor layer, taking into account the profile of the concentration of gas molecules in the layer, has been implemented into the equation of Ingebrigtsen, which enabled us to obtain analytical expressions for the relative changes in surface wave velocity in the steady state. The results of the analysis show that there is an optimum thickness of layer sensor for which an acoustoelectric effect (change in the acoustic wave velocity) is the highest.
Źródło:
Acta Physica Polonica A; 2013, 124, 3; 432-435
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
$WO_3-Pd$ Structure in SAW Sensor for Hydrogen Detection
Autorzy:
Hejczyk, T.
Urbańczyk, M.
Powiązania:
https://bibliotekanauki.pl/articles/1493196.pdf
Data publikacji:
2011-10
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
68.35.Iv
07.07.Df
Opis:
In the paper a new sensor structure for surface acoustic wave gas system is presented. A bilayer structure $WO_3-Pd$ thin films may be useful for hydrogen detection in low concentration in air. A bilayer sensor structure of tungsten oxide $WO_3$ with a very thin catalytic film of palladium on the top has been studied for gas-sensing application at room temperature (about 25°C) in surface acoustic wave system. The bilayer structure of $WO_3$ layers with a thickness of about 50 nm, 100 nm and 150 nm was made onto a $LiNbO_3$ Y-cut Z-propagating substrate by means of the vacuum sublimation method using a special aluminum mask. The vapor source consisted of commercially available $WO_3$ powder (Fluka 99.9%) and molybdenum heater. The thin palladium (Pd) layer (about 10 nm) was made separately on each $WO_3$ layer by means of vapor deposition in high vacuum. There have been investigated three structures: 50 nm $WO_3$ + 10 nm Pd, 100 nm $WO_3$ + 10 nm Pd and 150 nm $WO_3$ + 10 nm Pd in three canal surface acoustic wave system with reference oscillator. Numerical results obtained by analysis of the surface acoustic wave gas sensor model have been compared with experimental results.
Źródło:
Acta Physica Polonica A; 2011, 120, 4; 616-620
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surface Acoustic Wave Vibration Sensors for Linear Electronic Warning Systems
Autorzy:
Filipiak, J.
Solarz, L.
Steczko, G.
Powiązania:
https://bibliotekanauki.pl/articles/1795794.pdf
Data publikacji:
2009-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
43.35.Pt
68.35.Iv
Opis:
The topic of the paper is analysis of feasibility of surface acoustic wave vibration sensors for linear electronic warning systems. In linear warning systems localisation of the object is realised by pointing out the sensors which detect vibrations caused by the object. The information sent out by the detector enables identification of the sensor and its state. The sensor contains surface acoustic wave delay line in four-terminal network. The delay line is formed at the surface of piezoelectric plate. The vibrations of the plate are caused by vibrations of the medium surrounding the sensor. The frequency of the input signal is equal to the working frequency of delay line. The phase of the output signal is shifted in comparison with the input signal. The frequency of the phase shift would be equal to the resonance frequency of the sensor plate. The change of the output signal amplitude would be proportional to the amplitude of plate vibrations. The measured amplitude and frequency of the output signal would be registered by simple electronic devices. The measurements give us knowledge which sensor vibrates and the intensity of these vibrations. Such sensors enable construction of the electronic warning system.
Źródło:
Acta Physica Polonica A; 2009, 116, 3; 302-306
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bilayer Structures of $NiO_{x}$ and Pd in Surface Acoustic Wave and Electrical Gas Sensor Systems
Autorzy:
Jakubik, W.
Urbańczyk, M.
Maciak, E.
Pustelny, T.
Powiązania:
https://bibliotekanauki.pl/articles/1795797.pdf
Data publikacji:
2009-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.25.Fe
77.65.Dq
43.35.Pt
68.35.Iv
07.07.Df
Opis:
A bilayer sensor structure of nickel oxide $NiO_x$ ( ≈ 60 nm) with a very thin film of palladium (Pd ≈ 18 nm) on the top, has been studied for gas-sensing application at relatively low temperatures of about 30°C and 60°C. The bilayer structure was obtained by rf sputtering and by vacuum deposition (first the $NiO_{x}$ and then the Pd film) onto a $LiNbO_{3}$ Y-cut Z-propagating substrate, making use of the surface acoustic wave method, and additionally (in the same technological processes) onto a glass substrate with a planar microelectrode array for simultaneous monitoring of the planar resistance of the layered structure. Such a bilayer structure was investigated in a low concentration range (from 50 ppm to 400 ppm in air) of nitrogen dioxide $(NO_{2})$, carbon monoxide (CO) and ammonia $(NH_{3})$ in a dry and wet air atmosphere and in a medium hydrogen concentration (1-2.5%) in dry air. The $NiO_{x}$ and Pd bilayer structure interact rather weakly with $NO_{2}$ molecules but with CO and $NH_{3}$ this interaction is much greater, especially at higher temperature ( ≈ 60°C). The hydrogen sensitivity is on the medium level, not exceeding 600 Hz (relative change in the differential frequency of ≈ 2.3%) at interaction temperature of 35°C.
Źródło:
Acta Physica Polonica A; 2009, 116, 3; 315-320
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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