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Wyszukujesz frazę "Drosophila" wg kryterium: Temat


Tytuł:
The spotted wing drosophila Drosophila suzukii (Matsumura, 1931) – monitoring and first records in Poland
Autorzy:
Labanowska, B.H.
Piotrowski, W.
Powiązania:
https://bibliotekanauki.pl/articles/2012.pdf
Data publikacji:
2015
Wydawca:
Instytut Ogrodnictwa
Tematy:
spotted wing
Drosophila
Drosophila suzukii
monitoring
Polska
identification
Źródło:
Journal of Horticultural Research; 2015, 23, 2
2300-5009
Pojawia się w:
Journal of Horticultural Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The toxic effect of aluminium and its supposable mechanism in Drosophila
Autorzy:
Kiss, A S
Kiss, I.
Csikkel-Szolnoki, A.
Powiązania:
https://bibliotekanauki.pl/articles/15648.pdf
Data publikacji:
2007
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
toxic effect
aluminium
magnesium
sodium
Drosophila
membrane rigidity
Drosophila melanogaster
toxicity mechanism
Opis:
During the early epoch of biological evolution, aluminium was not available for the primitive organisms because of the low solubility of aluminium compounds. This can explain why aluminium is toxic for the present-day living organisms. We studied the toxic effect of aluminium by feeding Drosophila melanogaster adults for 24 hrs. with a 1% sugar solution containing different concentrations of aluminium sulphate. The effect of magnesium chloride was also tested in combination with aluminium. After 24 hrs. we calculated the survival rate, and solubilised the flies in concentrated nitric acid in a microwave oven. The Al, Na, Mg and Zn content of the solubilised flies was measured with the ICP-AES method. We found no change in the Zn content while the Al and Mg content changed according to the treatment, and the Na content decreased significantly (20-30%) in all the cases. We suppose that the flies were mainly killed by the elevated sodium efflux resulting in a decreased intracellular pH. The cause of the elevated Na efflux could be the increased rigidity of the cell membrane caused by the aluminium. We discuss the experimental results and the supposable mechanism of toxicity.
Źródło:
Journal of Elementology; 2007, 12, 4; 281-285
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Definition of immunogenic carbohydrate epitopes.
Autorzy:
Paschinger, Katharina
Fabini, Gustáv
Schuster, David
Rendić, Dubravko
Wilson, Iain
Powiązania:
https://bibliotekanauki.pl/articles/1041365.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cross-reactivity
allergy
Caenorhabditis
plant
Drosophila
Opis:
Carbohydrates are known as sources of immunological cross-reactivity of allergenic significance. In celery and in cypress pollen, the major allergens Api g 5 and Cup a 1 are recognised by antisera raised against anti-horseradish peroxidase and by patients' IgE which apparently bind carbohydrate epitopes; mass spectrometric analysis of the tryptic peptides and of their N-glycans showed the presence of oligosaccharides carrying both xylose and core α1,3-fucose residues. Core α1,3-fucose residues are also a feature of invertebrates: genetic and biochemical studies on the fruitfly Drosophila melanogaster, the parasitic trematode Schistosoma mansoni and the nematode worm Caenorhabditis elegans indicate that these organisms possess core α1,3-fucosyltransferases. Various experiments have shown that fucosyltransferases from both fly and worm are responsible in vivo and in vitro for the synthesis of N-glycans which cross-react with anti-horseradish peroxidase; thus, we can consider these enzymes as useful tools in generating standard compounds for testing cross-reactive carbohydrate epitopes of allergenic interest.
Źródło:
Acta Biochimica Polonica; 2005, 52, 3; 629-632
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Healing Effect of Cimin Grape Against Toxic Effects of ZnOTiO₂ Nanocomposite
Autorzy:
Atici, T.
Altun Çolak, D.
Powiązania:
https://bibliotekanauki.pl/articles/1031677.pdf
Data publikacji:
2017-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
ZnOTiO₂
Drosophila melanogaster
Cimin Grape
Survival Rate
Offspring Number
Opis:
Today, occurrence of nanotechnology is making life easier, increasing the individual happiness and attracts attention to the benefits to be provided by it. As with any technology, nanotechnology also has risks, which are discussed here. In this study, toxic effects of ZnOTiO₂ nanocomposite on various growth parameters of Drosophila melanogaster and removal of these effects by Cimin grape ( Vitis vinifera L. ssp., Cimin) were investigated. For this purpose, assessment of the number of offspring and the survival rate were performed by feeding flies with ZnOTiO₂ (1 mg/ml) and Cimin grape seed and fruit extracts (5 and 10 mg/ml). In the first stage, larvae of the the same age were put into the medium of each application group and the adult individuals were recorded. In the second stage, in order to determine the number of offspring in all treatment groups, in a set of experiments the grape extracts and ZnOTiO₂ were only applied to the female members, while in another set of experiments, the grape extracts and ZnOTiO₂ were applied only to male members, belonging to the same application group. The total number of flies developed from the eggs laid during ten days of pair mating was counted. As a result, survival rate and the offspring number in the application groups, that were only exposed to ZnOTiO₂ were found to show a decline, compared with the other groups. At the same time, the values obtained from the groups, exposed to the ZnOTiO₂ and grape extracts together, were close to control group values. This result supports the healing effects of Cimin grape, which is abundant in Erzincan.
Źródło:
Acta Physica Polonica A; 2017, 132, 3; 919-921
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Functionality versus strength - has functional selection taken place in the case of the ecdysteroid receptor response element?
Autorzy:
Grad, Iwona
Kochman, Marian
Ożyhar, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1043745.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ultraspiracle
nuclear receptor
Drosophila
protein-DNA interaction
ecdysteroid receptor
20-hydroxyecdysone
Opis:
Nuclear receptors are ligand-dependent transcription factors responsible for controlling differentiation, growth and development of higher eukaryotes. Three amino acids within the recognition α-helix of the DNA-binding domain of the nuclear receptors constitute the so-called "P-box" which determines response element specificity. In the ultraspiracle (Usp) protein, which together with EcR forms the heterodimeric ecdysone receptor, the P-box residues are E19, G20 and G23. Substitution of E19, the most characteristic amino acid for estrogen receptor-like P-boxes, with alanine showed that the mutation did not appreciably alter the affinity of the wild-type Usp DNA-binding domain (UspDBDWT) for a probe containing natural ecdysone response element (hsp27wt). Since in many cases E19 contacts a G/C base pair in position -4, which is absent in hsp27wt, we analysed the interaction of UspDBDWT, E19A and other P-box region mutants with the hsp27wt derivative which contains a G/C instead of an T/A base pair in position -4. UspDBDWT exhibited higher affinity for this element than for hsp27wt. Moreover, a different interaction pattern of P-box region mutants was also observed. Thus we conclude that the E19 residue of UspDBD is not involved in any hsp27wt sequence-discerning contacts. However, substitution of the hsp27wt T/A base pair in position -4 with G/C generates target sequence with distinct functional characteristics and possibly with a new specificity. These results could serve as a basis for understanding the role of the presence of a T/A or G/C base-pair in the position -4 in the two types of ecdysone response elements found in nature.
Źródło:
Acta Biochimica Polonica; 2002, 49, 3; 747-756
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Drosophila melanogaster (Meigen, 1830): A Potential Model for Human Diseases
Autorzy:
Adesola, Ridwan Olamilekan
Lawal, Jadalhaq Taiwo
Oladele, Oluwatobi Emmanuel
Powiązania:
https://bibliotekanauki.pl/articles/1031442.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Drosophila melanogaster
Huntington’s disease
human diseases
neurodegenerative disease
spinocerebellar ataxia type 3
Opis:
Over some time, Drosophila melanogaster (Meigen, 1830), commonly called fruit fly, has been used as a model organism in both scientific and medical research. Drosophila in comparison with other mammalian species shares some basic features like physiological, biological, biochemical, and neurological resemblances which make them suitable for use for biomedical research. Fruit fly can be maintained efficiently at a reduced cost in the laboratory, and it is endorsed as an alternative model compared to other vertebrates. It is confirmed and documented that almost 75 % of human disease-causing genes have functional similarities in Drosophila. Nevertheless, the use of D. melanogaster as a model organism was not narrowed to genetic research only, but several experiments. The use of this organism as a model for human diseases has also led to findings like neurodegenerative diseases, Huntington’s disease, spinocerebellar ataxia type 3, cancer, cardiovascular, inflammation and infectious diseases, and metabolic disorders. The fly is used as an ideal model organism for neurodegenerative disease studies such as Alzheimer’s and Parkinson’s, which have become more predominant in today's aging population due to its complex nervous system which conserved neurological function, and the human disease-related loci. In this review, we presented and discussed Drosophila melanogaster as a model to study several human diseases.
Źródło:
World News of Natural Sciences; 2021, 36; 42-59
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rytmy biologiczne i mechanizm zegara okołodobowego w mózgu - nagroda Nobla 2017
Autorzy:
Bilska, B.
Doktor, B.
Pyza, E.
Powiązania:
https://bibliotekanauki.pl/articles/845341.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
fizjologia
medycyna
Nagroda Nobla 2017
rytmy biologiczne
zegar okolodobowy
melatonina
muszka owocowa
Drosophila melanogaster
Źródło:
Wszechświat; 2018, 119, 01-03
0043-9592
Pojawia się w:
Wszechświat
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The value of interdisciplinary research: lessons from the 2017 Nobel Prize in chronobiology
Autorzy:
Giebultowicz, J.M.
Powiązania:
https://bibliotekanauki.pl/articles/1666.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
interdisciplinary research
Nobel Prize
laureate
chronobiology
physiology
medicine
circadian rhythm
biological clock
Drosophila
human health
Opis:
Since 1901, the Nobel Prize has been awarded to scientists who have made the most important discoveries for the benefit of humanity. The 2017 Nobel Prize in Physiology or Medicine was awarded jointly to Jeffrey C. Hall, Michael Rosbash and Michael W. Young “for their discoveries of molecular mechanisms controlling the circadian rhythm.” It may be surprising to learn that those three scientists dedicated their entire careers to research on the fruit fly, Drosophila melanogaster. However, as their studies progressed, it became increasingly clear that the mechanism of the biological clock that they discovered in Drosophila is very similar to a timekeeping mechanism present in mammals, including humans. Through interdisciplinary work between scientists performing basic research on model organisms and doctors working in medical schools, we have learned over time that daily rhythms support human health while disruption of these rhythms is associated with a range of pathological disorders such as cardiovascular problems, metabolic, neurological, and many other diseases. This short review will highlight critical milestones on the way to understanding biological clocks, focusing on the roles played by the three Nobel Prize winners.
Źródło:
Medical Science Pulse; 2018, 12, 1
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Animal Dicer and plant Dicer-like proteins
Autorzy:
Tworak, A.
Urbanowicz, A.
Podkowinski, J.
Figlerowicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/80710.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
eukaryotic organism
RNA molecule
double stranded RNA
Dicer-like protein
biogenesis
Drosophila melanogaster
microRNA
small interfering RNA
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human genome sequenced: achievements and shortcomings in big science
Autorzy:
Blin, N
Powiązania:
https://bibliotekanauki.pl/articles/2041227.pdf
Data publikacji:
2001
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
science
worm
molecular genetics
fly
euchromatic genome
genome evolution
Drosophila
nucleotide
DNA
Caenorhabditis
human genome
genetic variation
Źródło:
Journal of Applied Genetics; 2001, 42, 4; 399-403
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mechanizm zegara biologicznego. Nagroda Nobla 2017 w dziedzinie fizjologii lub medycyny
Mechanism of circadian clock. The 2017 Nobel Prize in physiology or medicine
Autorzy:
Giebultowicz, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/1033710.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
biological clock
circadian rhythms
clock genes
Drosophila melanogaster
Nobel Prize
geny zegarowe
nagroda Nobla
rytmy okołodobowe
zegar biologiczny
Opis:
Since 1901, the Nobel Prize has been awarded to scientists who have made the most important discoveries for the benefit of humanity. The 2017 Nobel Prize in Physiology or Medicine was awarded jointly to Jeffrey C. Hall, Michael Rosbash and Michael W. Young “for their discoveries of molecular mechanisms controlling the circadian rhythm.” It may be surprising to learn that those three scientists dedicated their entire careers to research on the fruit fly, Drosophila melanogaster. However, as their studies progressed, it became increasingly clear that the mechanism of the biological clock that they discovered in Drosophila is very similar to a timekeeping mechanism present in mammals, including humans. Through interdisciplinary work between scientists performing basic research on model organisms and medical doctors, we have learned over time that daily rhythms support human health while disruption of these rhythms is associated with a range of pathological disorders such as cardiovascular problems, metabolic, neurological, and many other diseases. This short review highlights critical milestones on the way to understanding biological clocks, focusing on the roles played by the three Nobel Prize winners.
Od roku 1901 Nagroda Nobla jest przyznawana naukowcom za najważniejsze odkrycia służące dobru ludzkosci. Nagrodę Nobla w dziedzinie fizjologii lub medycyny w 2017 roku otrzymali trzej amerykańscy uczeni Jeffrey C. Hall, Michael Rosbash i Michael W. Young "za odkrycie mechanizmu molekularnego, który kontroluje rytmy okołodobowe". Może się to wydać zaskakujące, ale ci trzej nobliści poświęcili swoje kariery naukowe badaniom nad muszką owocową, Drosophila melanogaster. Jednak w miarę postępu ich badań stawało się coraz bardziej oczywiste, że mechanizm zegara biologicznego, odkryty u muszki Drosophila, jest bardzo podobny do zegara, który posiadają ssaki, łącznie z człowiekiem. Interdyscyplinarna współpraca między naukowcami prowadzącymi badania podstawowe na organizmach modelowych i lekarzami prowadzącymi badania kliniczne ujawniła istotną rolę rytmów dobowych w utrzymaniu zdrowia człowieka. Dlugotrwałe zakłócenie tych rytmów stanowi czynnik ryzyka wielu patologii, takich jak choroby serca, cukrzyca, otyłość czy choroby układu nerwowego. Artykuł krótko podsumowuje odkrycia, stanowiące kamienie milowe na drodze poznania mechanizmu zegara biologicznego, ze szczególnym uwzględnieniem roli trzech noblistów 2017 w tym procesie.
Źródło:
Kosmos; 2018, 67, 2; 245-249
0023-4249
Pojawia się w:
Kosmos
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Muszka - najlepszy przyjaciel neurobiologa
Autorzy:
Damulewicz, M
Powiązania:
https://bibliotekanauki.pl/articles/845396.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
owady
muszka owocowa
Drosophila melanogaster
organizmy modelowe
badania naukowe
chronobiologia
rytmy biologiczne
badania molekularne
badania genetyczne
badania neurofarmakologiczne
Źródło:
Wszechświat; 2010, 111, 04-06; 92-96
0043-9592
Pojawia się w:
Wszechświat
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Na początku było "white"
Autorzy:
Gorlich, A.
Gorska-Andrzejak, J.
Powiązania:
https://bibliotekanauki.pl/articles/846472.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
genetyka
historia nauki
organizmy modelowe
muszka owocowa
Drosophila melanogaster
mutacje
badania genetyczne
badania modelowe
biologia rozwoju
choroby neurodegeneracyjne
Źródło:
Wszechświat; 2013, 114, 04-06
0043-9592
Pojawia się w:
Wszechświat
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Jak "tyka" zegar biologiczny
Autorzy:
Gorska-Andrzejak, J.
Powiązania:
https://bibliotekanauki.pl/articles/856682.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
chronobiologia
rytmy biologiczne
rytmy okolodobowe
zegar biologiczny
mechanizm dzialania
muszka owocowa
Drosophila melanogaster
gen per
gen tim
sprzezenie zwrotne
ssaki
jadra nadskrzyzowaniowe
Źródło:
Wszechświat; 2011, 112, 04-06
0043-9592
Pojawia się w:
Wszechświat
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wykrywanie obecnosci zwiazkow rakotworczych w srodowisku ze szczegolnym uwzglednieniem testow na muszce owocowej [Drosophila melanogaster]
Autorzy:
Krogulski, A
Powiązania:
https://bibliotekanauki.pl/articles/877652.pdf
Data publikacji:
1992
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
Drosophila melanogaster
nowotwory
choroby czlowieka
muszka owocowa
mutagennosc
testy immunologiczne
genetyka zwierzat
substancje rakotworcze
cancer
human disease
fruit fly
mutagenicity
immunological test
animal genetics
carcinogenic substance
Opis:
Praca zawiera krótki przegląd metod wykrywania związków rakotwórczych w środowisku człowieka przy podkreśleniu zalet stosowania testu mutacji i rekombinacji u muszki owocowej - Drosophila melanogaster.
The increasing exposure of the human population to mutagen and carcinogenic substances necessitates research and introduction of methods for their detection. The diersity of these dangerous substances in the environment requires, the application of the chemical and biological tests. The latter allow testing of chemical mixtures of unknown composition. The advantages and limitations of short-term tests are presented. Among these the advantages of somatic mutation and recombination tests are described in more detail on Drosophila melanogaster. The subcellular structure, enzymes produced and the course of metabolic processes in Drosophila are similar as in man. It is possible, therefore, to detect the numerous mutagens undetectable in tests on bacteria. These test are relaitvely simple, not expensive and do not require expensive apparatus or preliminary activation of promuta- gens necessary in tests on bacteria.
Źródło:
Roczniki Państwowego Zakładu Higieny; 1992, 43, 3-4; 271-275
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł

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