- Tytuł:
- The influence of substrate composition on the physicochemical properties of hydrogels with chitosan
- Autorzy:
-
Szcześniak, Maria
Grimling, Bożena
Meler, Jan
Pluta, Janusz - Powiązania:
- https://bibliotekanauki.pl/articles/1034687.pdf
- Data publikacji:
- 2016
- Wydawca:
- Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
- Tematy:
-
Carbopl 934P
PVP
chitosane
hydrogels
pharmaceutical availability
rheological parameters - Opis:
- The aim of the study was to evaluate the effect of Carbopol 934 P and PVP K 90 on the rheological properties of chitosan gels. Hydrogels were prepared with hydrocortisone containing chitosan, Carbopl 934P, PVP, propylene glycol-1,2 or polyethyleneglycol 400 and glycerol. Addition of polymers had positive influence on the dispersion of hydrogels. The studied gels have thixotropic properties, their viscosity increases with the increase of the concentration of polymers. Increase of the content of polyvinylpyrrolidone K 90 and Carbopol 934 P increases the consistence, gels are more firm and cohesive. Gels with 5 % chitosane, 15% polyvinylpyrrolidone K 90 and Carbopol 934 P in the presence of additives have prolonged half release period of hydrocortisone.
- Źródło:
-
Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 187-191
1896-5644 - Pojawia się w:
- Progress on Chemistry and Application of Chitin and its Derivatives
- Dostawca treści:
- Biblioteka Nauki
Artykuł