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Tytuł:
Весь-человек Михаилa Пришвинa (на материале повести „Корабельная чаща”)
Autorzy:
Szubin, Roman
Powiązania:
https://bibliotekanauki.pl/articles/1022741.pdf
Data publikacji:
2019-08-08
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
all-man
hermeneutics
all-unity
Mikhail Prishvin
Vardan Hayrapetyan
Opis:
Article is devoted to studying a concept of all-unity, all-man (rus. всеединство, всечеловек) in the story The Ship Forest (Korabel’naya Chashcha) of the Russian writer Mikhail Prishvin. The idea of all-unity, of unity common to all mankind, peculiar to the Russian thought, has found expression in a symbol All-man (Весь-человек). The image-symbol is considered through a number of collective forms and personalities, its language form, conceptual filling, development of an image in the case of diaries of Prishvin is investigated. The author focuses on the problem of sectarianism in the Russian culture and radicalization of collective life at the beginning of the 20th century in the Bolshevism. As a method hermeneutical developments of Vardan Hayrapetyan in the field of the Russian folklore are applied. The symbol of the All-man corresponds to a mytheme of a first-man and with hermeneum the man of the world (the world person), embodying the archaic idea of rescue.
Źródło:
Studia Rossica Posnaniensia; 2019, 44, 1; 155-166
0081-6884
Pojawia się w:
Studia Rossica Posnaniensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA in pediatric leukemia patients
Autorzy:
Kodroń, Agata
Ghanim, Magda
Krawczyk, Katarzyna
Stelmaszczyk-Emmel, Anna
Tońska, Katarzyna
Demkow, Urszula
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1038705.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
pediatric ALL
mtDNA
chemotherapy
Opis:
Numerous studies of mitochondrial DNA (mtDNA) in cancer have shown differences between mtDNA sequences in tumor and normal tissue and at various stages of cancer treatment in the same patient. However, there is little data on acute lymphoblastic leukemia (ALL), the most common type of leukemia in children. In this study we compared mitochondrial sequence variation in the D-loop region and in 5 genes of mtDNA in bone marrow samples of 6 pediatric patients with ALL at various stages of therapy. We found several common polymorphisms and one variant at position 3688 whose level varied during leukemia treatment. Our results suggest that mitochondrial DNA mutations, whose levels change during patient treatment, could be potential biomarkers for monitoring treatment efficacy and disease progression.
Źródło:
Acta Biochimica Polonica; 2017, 64, 1; 183-187
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A Sokoban-type game and arc deletion within irregular digraphs of all sizes
Autorzy:
Dziechcińska-Halamoda, Zyta
Majcher, Zofia
Skupień, Zdzisław
Powiązania:
https://bibliotekanauki.pl/articles/743481.pdf
Data publikacji:
2007
Wydawca:
Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
Tematy:
irregular digraph
all sizes
Opis:
Digraphs in which ordered pairs of out- and in-degrees of vertices are mutually distinct are called irregular, see Gargano et al. [3]. Our investigations focus on the problem: what are possible sizes of irregular digraphs (oriented graphs) for a given order n? We show that those sizes in both cases make up integer intervals. The extremal sizes (the endpoints of these intervals) are found in [1,5]. In this paper we construct, with help of Sokoban-type game, n-vertex irregular oriented graphs (irregular digraphs) of all intermediate sizes.
Źródło:
Discussiones Mathematicae Graph Theory; 2007, 27, 3; 611-622
2083-5892
Pojawia się w:
Discussiones Mathematicae Graph Theory
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vitro activity of oxazaphosphorines in childhood acute leukemia: Preliminary report.
Autorzy:
Styczyński, Jan
Wysocki, Mariusz
Dębski, Robert
Balwierz, Walentyna
Rokicka-Milewska, Roma
Matysiak, Michał
Balcerska, Anna
Kowalczyk, Jerzy
Wachowiak, Jacek
Sońta-Jakimczyk, Danuta
Chybicka, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/1043830.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ALL
leukemia
sensitivity
glufosfamide
resistance
Opis:
Glufosfamide (β-D-glucosyl-ifosfamide mustard) is a new agent for cancer chemotherapy. Its pharmacology is similar to commonly used oxazaphosphorines, but it does not require activation by hepatic cytochrome P-450 and preclinically demonstrates lower nephrotoxicity and myelosuppression than ifosfamide. The aim of the study was a comparison of the drug resistance profiles of glufosfamide and other oxazaphosphorines in childhood acute leukemias. Leukemic cells, taken from children with ALL on diagnosis (n = 41), ALL on relapse (n = 12) and AML on diagnosis (n= 13) were analyzed by means of the MTT assay. The following drugs were tested: glufosfamide (GLU), 4-HOO-ifosfamide (IFO), 4-HOO-cyclophosphamide (CYC) and mafosfamide cyclohexylamine salt (MAF). In the group of initial ALL samples median cytotoxicity values for GLU, IFO, CYC and MAF were 15.5, 33.8, 15.7 and 7.8 μM, respectively. In comparison with initial ALL samples, the relative resistance for GLU and IFO in relapsed ALL samples was 1.9 (p = 0.049) and 1.3 (ns), and in initial AML samples 31 (p < 0.001) and 5 (p = 0.001), respectively. All oxazaphosphorines presented highly significant cross-resistance. Glufosfamide presented high activity against lymphoblasts both on diagnosis and on relapse.
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 221-225
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Design of all-optical time-division multiplexing scheme with the help of microring resonator
Autorzy:
Rakshit, J K
Roy, J N
Powiązania:
https://bibliotekanauki.pl/articles/173771.pdf
Data publikacji:
2014
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
all-optical multiplexing
all-optical signal processing
optical logic gate
optical time-division multiplexing (OTDM)
microring resonator
Opis:
Optical time-division multiplexing is a natural multiplexing technique leading to terabit/s transmission capacity for many services that will be found in near future optical telecommunication networks. In this paper we have conducted a theoretical study of all-optical time-division multiplexing switching using GaAs-AlGaAs based microring resonator together with performances characteristics. The proposed circuit is more compact, simple and will be helpful in designing all-optical telecommunication circuits in near future. Numerical simulation results confirming described methods are given in this paper.
Źródło:
Optica Applicata; 2014, 44, 1; 39-54
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Charakterystyka i częstość występowania koekspresji w ostrych białaczkach u dzieci
Characteristics and frequency of coexpression in acute lymphoblastic leukemia in children
Autorzy:
Kaufmann, Jolanta
Mazur, Bogdan
Szczepański, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1038745.pdf
Data publikacji:
2012
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
all
aml
koekspresja
immunofenotyp
coexpression
immunophenotypic profile
Opis:
INTRODUCTION Acute lymphoblastic leukemia (ALL) is the most common form of leukemia and makes about 80% of all developmental age leukemias, 70–80% of which come from B lymphocyte line and only 15–20% from T lymphocyte line. Acute myeloid leukemia (AML) makes up about 20% of all leukemias detected among children. Cytometric analysis of leukemic cells immunophenotype allows a precise determination of each cell line status, degree of maturity and occurrence of coexpression phenomenon. MATERIAL AND METHODS 275 cases of children with acute leukemia, diagnosed in the University Ward of Pediatrics and Hematology in Zabrze in the years 1995–2007. The material consisted of bone marrow or peripheral blood containing not less than 80% blast cells. The study applied the method of whole blood and marrow marking with the subsequent erythrocyte lysis. FITC, PerCP or PE fluorochrome-coupled antibodies were used and they were directed against CD1a, CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD13, CD14, CD15, CD19, CD20, CD22, CD33, CD34, CD117, HLA-DR, MPO, TdT. RE SULT S Patient group with acute leukemia includes 275 cases. The biggest group consists of patients with diagnosed acute precursor leukemia from B lymphocyte line – 70.55% while the number of cases with T-ALL (14.91%) and AML (14.55%) were similar. The most frequent coexpression belonged to the coexpression of determinants characteristic for the myeloid line: CD13, CD33, CD15, which were observed in 28.2% of cases among the studied ones. The coexpression of T lymphocyte line antigens was noticed only in individual cases and those were determinants CD1a, CD2, CD4, CD5, CD7 which occur in 4.5% of all cases of precursor leukemia from B lymphocyte line. In the group of leukemias from T lymphocyte line the coexpression from other cell lines was noticed in 26.8% of cases, most of which were about the expression of myeloid antigens: CD13, CD33, CD14. The coexpression of antigen CD19 was noticed only in 3 cases (7.3%). There was detected a small number of cases with children with AML where there were noticed antigens from other cell lines on leukemia cells. The coexpressions CD19, CD2 and CD4 were discovered.tion and to monitor remissions during treatment, and additionally, to find out a possible disease recurrence in bone marrow and CSF.
WSTĘP Ostra białaczka limfoblastyczna (acute lymphoblastic leukemia – ALL) jest najczęstszą postacią białaczki u dzieci i stanowi około 80% wszystkich białaczek wieku rozwojowego, z czego 70–80% pochodzi z linii limfocyta B, a jedynie 15–20% z linii limfocyta T. Ostra białaczka nielimfoblastyczna (acute myeloid lymphoblastic – AML) stanowi około 20% wszystkich białaczek wykrywanych u dzieci. Cytometryczna analiza immunofenotypu komórek białaczkowych pozwala określić przynależność do danej linii komórkowej oraz stopień dojrzałości, a także wykryć fenotypy nietypowe. Celem pracy było określenie częstości i rodzaju występowania koekspresji w ostrych białaczkach u dzieci. MATERIAŁ I METODY Przeanalizowano grupę 275 dzieci z ALL diagnozowanych w Klinice Pediatrii i Hematologii w Zabrzu w latach 1995–2007. Materiałem był szpik kostny lub krew obwodowa zawierająca nie mniej niż 80% komórek blastycznych. W badaniach zastosowano metodę znakowania pełnej krwi lub szpiku z lizą erytrocytów. Użyto przeciwciał sprzężonych z fl uorochromami FITC, PerCP lub PE skierowanych przeciwko antygenom: CD1a/ /CD2/CD3/CD4/CD5/CD7/CD8/CD10/CD13/CD14/CD15/CD19/ /CD20/CD22/CD33/CD34/CD117/HLA-DR/MPO/TdT. WYNIKI Największą grupę stanowią pacjenci z białaczką prekursorową z linii limfocyta B – 70,55%, zaś liczby przypadków z T-ALL (14,91%) i AML (14,55%) są do siebie zbliżone. Wśród B-ALL największy odsetek koekspresji dotyczył antygenów mieloidalnych: CD13+ (7,2% przypadków), CD33+ (w 7,7%), CD13+CD33+ (8,7%) oraz CD15+ (4,6%). Koekspresja antygenów z linii limfocyta T stanowi niewielki odsetek: CD7+ wykryto w 1,5% przypadków B-ALL, CD2+ w 1,5%, CD4+ w 0,5%, CD1a w 0,5% i CD5+ w 0,5%. W przypadku T-ALL koekspresje z innych linii komórkowych zanotowano w 26,8% przypadków, z czego większość dotyczyła antygenów mieloidalnych: CD13, CD33, CD14, zaś obecność CD19 wykryto jedynie w 3 przypadkach. Antygen CD13+ zanotowano w 7,3% przypadków T-ALL, CD13+CD33+ w 9,8%, CD14+ w 2,4%. W AML stwierdzono obecność koekspresji: CD19 w 3 (7,5%) przypadkach, CD2 w 5 (12,5%) oraz CD4 w 2 (5,0%) przypadkach. WNIOSKI Obecność nietypowych immunofenotypów, w tym występowanie antygenów z innych linii komórkowych na komórkach blastycznych, stanowi swoisty dla pacjenta marker diagnostyczny pozwalający monitorować osiąganie remisji w trakcie leczenia, identyfikować białaczkowe nacieczenie PMR.
Źródło:
Annales Academiae Medicae Silesiensis; 2012, 66, 3; 20-26
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Burial crypts in solid rock – a geophysical case study of a small church with a unique polychrome in Szydłów (S Poland)
Autorzy:
Zieliński, Artur
Łyskowski, Mikołaj
Mazurkiewicz, Ewelina
Lubarska, Kinga Wiktoria
Powiązania:
https://bibliotekanauki.pl/articles/184488.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
Szydłów
All Saints’ Church
GPR
wall polychrome
crypt
Opis:
Lesser Poland (Małopolska) is a historic region of Poland. The presented case study was undertaken in the All Saints’ Church in the town of Szydłów, in which conservation and restoration works were carried out to preserve Gothic wall paintings by identifying and eliminating the causes of their degradation, and these efforts were supported by geophysical surveying. The conducted studies constitute a step not only to determine the age of the construction of the Szydłów temple, but also to improve knowledge of medieval architecture and mural paintings in Lesser Poland. The geophysical research with application of GPR (Ground Penetrating Radar) helped to locate previously unknown structures under the temple floor. This survey indicated four, possibly connected, structural objects clearly visible in GPR profiles. Carried out works confirmed that anomalies visible on radargrams mark two crypts. This discovery of the hidden construction elements emphasizes and strengthens the earlier suppositions of the unique character of this temple.
Źródło:
Geology, Geophysics and Environment; 2019, 45, 2; 89-97
2299-8004
2353-0790
Pojawia się w:
Geology, Geophysics and Environment
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Platform one4all in implementating computer solutions in service oriented architecture
Autorzy:
Gąska, D.
Świć, A.
Powiązania:
https://bibliotekanauki.pl/articles/117858.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Promocji Wiedzy
Tematy:
platform one4all
Service-Oriented Architecture (SOA)
Opis:
The paper presents the foundations of building the systems of Service Oriented Architecture, SOA, their conception and influence on functioning of the whole enterprise. The newly presented platform one4all uses several computer products implementing as services for realization of the basic/fundamental business processes, communication and workflow management, project management, or the analysis of business activities.
Źródło:
Applied Computer Science; 2010, 6, 2; 95-106
1895-3735
Pojawia się w:
Applied Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Katyn Massacre – Basic Facts
Autorzy:
Komaniecka, Monika
Samsonowska, Krystyna
Szpytma, Mateusz
Zechenter, Anna
Powiązania:
https://bibliotekanauki.pl/articles/668509.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Papieski Jana Pawła II w Krakowie
Tematy:
Katyn massacre
Soviet policy
All-Union Communist Party (Bolsheviks)
Opis:
Katyn is a symbol of the criminal policy of the Soviet system against the Polish nation. The present study aims to demonstrate the basic facts of Katyn massacre – the execution of almost 22,000 people: Polish prisoners of war in Katyn, Kharkov, Kalinin (Tver) and also other Polish prisoners (soldiers and civilians), which took place in the spring of 1940 in different places of the Soviet Ukraine and Belarus republics based on the decision of the Soviet authorities, that is the Political Bureau of All-Union Communist Party (Bolsheviks) of March 5, 1940. This article refers not only to the massacre itself, but also its origin, historical processes and the lies accompanying Katyn massacre.
Źródło:
The Person and the Challenges. The Journal of Theology, Education, Canon Law and Social Studies Inspired by Pope John Paul II; 2013, 3, 2
2391-6559
2083-8018
Pojawia się w:
The Person and the Challenges. The Journal of Theology, Education, Canon Law and Social Studies Inspired by Pope John Paul II
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Platform one4all as Service Oriented Architecture (SOA) in implementing computer solutions
Autorzy:
Gąska, D.
Świć, A.
Powiązania:
https://bibliotekanauki.pl/articles/117850.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Promocji Wiedzy
Tematy:
Service-Oriented Architecture (SOA)
platform one4all
ERP
Opis:
The paper presents platform one4all uses several computer products implementing as services for realization of the basic/fundamental business processes, communication and workflow management, project management, or the analysis of business activities. The newly presented the foundations of building the systems of Service Oriented Architecture, SOA, their conception and influence on functioning of the whole enterprise.
Źródło:
Applied Computer Science; 2012, 8, 1; 64-76
1895-3735
Pojawia się w:
Applied Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł

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