- Tytuł:
- Encapsulation of chondrocytes in hydrogel systems effect of chitosan viscosity and microcapsule shape
- Autorzy:
-
Wasiak, I.
Ciach, T. - Powiązania:
- https://bibliotekanauki.pl/articles/185143.pdf
- Data publikacji:
- 2012
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Tematy:
-
microencapsulation
ACA microcapsule
Chondrocytes
mikrokapsułkowanie
mikrokapsułki ACA
chondrocyty - Opis:
- Alginate – chitosan – alginate multilayer hydrogel encapsulation systems were investigated for encapsulation of chondrocytes. Hydrogel is crosslinked due to ionic interaction between cationic chitosan and anionic alginate, and additionally by calcium ions. Two types of chitosan with molecular weight were investigated. Cells were encapsulated in two shape microcapsules, microbeads with diameter size 300 – 400 and 500 - 600 [mi]m and fibres with diameter 500 - 600 [mi]m. The work provides a detailed examination of the impact of the microencapsulation process on the growth of cells. The viability of chondrocytes can be influenced by the size of produced microcapsules, while the shape of microcapsules has no important significance on cell viability. The applied encapsulation methods do not contain harmful stages and create conducive conditions for cell growth. A possible application area of the developed system is dressing and regeneration of damaged joint cartilage.
- Źródło:
-
Chemical and Process Engineering; 2012, 33, 4; 529-538
0208-6425
2300-1925 - Pojawia się w:
- Chemical and Process Engineering
- Dostawca treści:
- Biblioteka Nauki
Artykuł