- Tytuł:
- Structural Changes of DPPC Bilayers Induced by Gemini Surfactant
- Autorzy:
-
Kida, W.
Kozak, M. - Powiązania:
- https://bibliotekanauki.pl/articles/1431597.pdf
- Data publikacji:
- 2012-04
- Wydawca:
- Polska Akademia Nauk. Instytut Fizyki PAN
- Tematy:
-
87.15.Zg
61.05.cf
87.64.km
87.16.dt - Opis:
- The phospholipid-gemini surfactant systems are promising agents for construction of lipoplexes for DNA delivery systems in gene therapy. In this work the influence of a gemini surfactant - 1,1'-(1,6-hexan)bis3-octyloxymethylimidazolium di-chloride) (IMI_Cl_C6_C8) on the structure and phase behaviour of aqueous suspensions of the fully hydrated phospholipid - 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) were characterised using small angle scattering of synchrotron radiation (SAXS), differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR). The surfactant studied caused a destabilisation of the lamellar phase typical of DPPC. Addition of the surfactant also shifted to lower temperatures and extended the range of the main phase transition
- Źródło:
-
Acta Physica Polonica A; 2012, 121, 4; 893-898
0587-4246
1898-794X - Pojawia się w:
- Acta Physica Polonica A
- Dostawca treści:
- Biblioteka Nauki
Artykuł