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    Wyświetlanie 1-4 z 4
    Tytuł:
    Development of an automation system for iodine-125 brachytherapy seed encapsulated by Nd:YAG laser welding
    Autorzy:
    Somessari, S. L.
    Feher, A.
    Sprenger, F. E.
    Rostelato, M. E. C. M.
    da Costa, F. E.
    Calvo, W. A. P.
    Powiązania:
    https://bibliotekanauki.pl/articles/147664.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    iodine-125 seeds
    prostate cancer
    brachytherapy
    Nd:YAG laser welding
    Opis:
    The aim of this work is to develop an automation system for iodine-125 radioactive seed production by Nd:YAG laser welding, which has been used successfully in low dose rate (LDR) brachytherapy treatment. This small seed consists of a welded titanium capsule, with 0.8 mm in diameter and 4.5 mm in length, containing iodine-125 adsorbed onto a silver rod. The iodine-125 seeds are implanted into the human prostate to irradiate the tumor for cancer treatment. Nowadays, the Radiation Technology Center, at Institute for Nuclear and Energy Research, Săo Paulo, Brazil (IPEN-CNEN/SP) imports and distributes 36,000 iodine-125 seeds per year, for the clinics and hospitals in the country. However, the Brazilian market potential is now over 8,000 iodine-125 seeds per month. The local production of these iodine-125 radioactive sources became a priority for the Institute, in order to reduce the price and the problems of prostate cancer management. It will permit to spread their use to a larger number of patients in Brazil. On the other hand, the industrial automation plays an important role for iodine-125 seeds in order to increase the productivity, with high quality and assurance, avoiding human factors, implementing and operating with good manufacturing practices (GMP). The technology consists of appliance electronic and electro-mechanical parts and components to control machines and processes. The automation system technology for iodine-125 seed production developed in this work was mainly assembled employing a programmable logic controller (PLC), a stepper motor, an Nd:YAG laser welding machine and a supervisory. The statistical repeatability of correctly encapsulated sealed sources with this automation system is greater than 95 per cent.
    Źródło:
    Nukleonika; 2011, 56, 4; 369-374
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Development of an irradiation system for a small size continuous run multipurpose gamma irradiator
    Autorzy:
    Calvo, W. A. P.
    Rela, P. R.
    Napolitano, C. M.
    Kodama, Y.
    Omi, N. M.
    da Costa, F.
    de Andrade e Silva, L. G.
    Powiązania:
    https://bibliotekanauki.pl/articles/148041.pdf
    Data publikacji:
    2009
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    multipurpose irradiator
    gamma irradiator
    compact irradiator
    cobalt-60 irradiator
    gamma facility
    Opis:
    The Radiation Technology Center from IPEN-CNEN/SP, Brazil, developed a revolutionary design and national technology, a small-sized continuous run and multipurpose industrial gamma irradiator, to be used as a demonstration facility for manufacturers and contract service companies, which need economical and logistical in-house irradiation system alternatives. Also, to be useful for supporting the local scientific community on development of products and process using gamma radiation, assisting the traditional and potential users on process validation, training and qualification of operators and radioprotection officers. The developed technology for this facility consists of a continuous tote box transport system, comprising a single concrete vault, where the automated transport system of products inside and outside of the irradiator utilizes a rotating door, integrated with the shielding, avoiding the traditional maze configuration. Covering 76 m2 of floor area, the irradiator design is a product overlap sources and the maximum capacity of cobalt-60 wet sources is 37 PBq. The performed qualification program of this multipurpose irradiator was based on AAMI/ISO 11137 standard, which recommends the inclusion of the following elements: installation and process qualification. The initial load of the multipurpose irradiator was 3.4 PBq with 13 cobalt-60 sources model C-188, supplied by MDS Nordion – Canada. For irradiator dose optimization, the source distribution was done using the software Cadgamma developed by IPEN-CNEN/SP. The polymethylmetacrylate (PMMA) dosimeter system, certified by the International Dose Assurance Service (IDAS) of the International Atomic Energy Agency (IAEA) was used for irradiator dose mapping. The economic analysis, performance concerning with dose uniformity and cobalt-60 utilization efficiency were calculated and compared with other commercial gamma irradiators available on the market.
    Źródło:
    Nukleonika; 2009, 54, 2; 93-97
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Simulation modelling of Vitória-Minas closed-loop rail network
    Modelagem de simulação do circuito fechado da ferrovia Vitória Á Minas
    Autorzy:
    Faria, C. H. F. de
    Cruz, M. M. da Costa
    Powiązania:
    https://bibliotekanauki.pl/articles/375477.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Śląska. Wydawnictwo Politechniki Śląskiej
    Tematy:
    railway
    simulation
    closed loop
    heavy haul
    transportation of iron ore
    rolling stock
    kolej żelazna
    symulacja
    pętla zamknięta
    transport rud żelaza
    tabor kolejowy
    Opis:
    This paper presents a closed loop simulation model that represents the mining logistics chain of the Vitória Minas Railway (VMR), Brazil. The simulator includes the loading process, circulation of loaded trains, unloading of ores for external and internal markets and the distribution of empty trains for new loads. General cargo and passengers trains are also included in the model, which, along with the queues formed in the circulation and the preventive and corrective maintenance of rolling stock, tracks and equipment, interfere with the transportation of iron ore. The primary objective of the iron ore transport is to meet the daily loading and unloading schedules and minimize queues by maximizing the operations at the loading and unloading points. The VMR simulator developed uses macro-mesoscopic approach with Monte Carlo simulation. To validate the simulator, we used actual data of the railway and compared with reality. We obtained a very good adhesion to the value of 2.9% for the validation scenario (Scenario 1) and 3.4% for the scenario with reducing the number of lots of wagons (Scenario 2). We concluded with this simulation that it is possible to reduce the number of GDE wagons without reducing the current level of productivity of the rail system.
    Este artigo apresenta o modelo de simulação do circuito fechado da rede logística de minério de ferro da ferrovia Vitória Á Minas (VMR), Brasil. O simulador inclui o processo de carregamento, circulação dos trens carregados, descarregamento para os mercados externos e internos e a distribuição dos trens vazios para novos carregamentos. Os trens de carga geral e de passageiros também foram incluídos no modelo, bem como suas filas de formação e as manutenções preventivas e corretivas do material rodante, que interferem no transporte do minério de ferro. O principal objetivo do transporte de minério de ferro é atender as programações de carregamento e descarregamento e minimizar as filas maximizando as operações nos pontos de carregamento e descarregamento. O simulador VMR desenvolvido utiliza uma abordagem macro-mesoscópica de simulação de Monte Carlo. Para validar o simulador, foi utilizado dados da ferrovia e comparado com a realidade. Obtivemos uma aderência muito de 2,9% para o cenário de validação (cenário 1) e 3,4% para o cenário com a redução do número de lotes de vagão (cenário 2). Concluímos que com esta simulação é possível reduz o número de lotes de vagões GDE sem reduzir a produtividade da ferrovia.
    Źródło:
    Transport Problems; 2015, T. 10, z. spec.; 125-139
    1896-0596
    2300-861X
    Pojawia się w:
    Transport Problems
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Seroprevalence of SARS-CoV-2 and assessment of epidemiologic determinants in Portuguese municipal workers
    Autorzy:
    Barros Ferreira, Nuno
    Pereira, Helena
    Pereira, Ana M.
    Azevedo, Luís F.
    Santos, Mariana
    Maranhão, Priscila
    Correia, Ricardo
    Fonseca, João A.
    Canedo, Paulo
    da Costa Pereira, Altamiro
    Sousa-Pinto, Bernardo
    Powiązania:
    https://bibliotekanauki.pl/articles/2084912.pdf
    Data publikacji:
    2022-06-08
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    SARS-CoV-2 infection
    COVID-19 pandemic
    COVID-19 virus
    COVID-19 serodiagnosis
    COVID-19 antibody testing
    SARS-CoV-2 infection serological testing
    Opis:
    ObjectivesTo assess the seroprevalence of SARS-CoV-2 antibodies in municipal employees of Northern Portugal during the first pandemic wave (May–June 2020) and its association with potentially related risk factors for infection.Material and MethodsThe authors assessed municipal employees of 2 cities in Northern Portugal, in whom serological tests to SARS-CoV-2 and an epidemiological survey were applied. The authors assessed the proportion of individuals presenting IgM and/or IgG antibodies to SARS-CoV-2, and evaluated the association between having positive serological test results, epidemiologic variables and clinical presentations. Reported symptoms were evaluated on their sensitivity, specificity, and predictive values.ResultsThe authors assessed 1696 employees, of whom 22.0% were firefighters, 10.4% were police officers, 10.3% were maintenance workers, and 8.1% were administrative assistants. The seroprevalence of SARS-CoV-2 infection was 2.9% (95% CI: 2.1–3.7%). Administrative assistants comprised the professional group with highest seroprevalence of SARS-CoV-2 (OR = 1.9 in the comparison with other occupational groups, 95% CI: 0.8–4.3, p = 0.126). The seroprevalence of SARS-CoV-2 infection among those who were in direct contact with COVID-19 patients in their professional activity was 3.9%, compared to 2.7% among those who were not in direct contact with such patients (OR = 1.5, 95% CI: 0.8–2.8, p = 0.222). The highest risk of infection was associated with the presence of a confirmed SARS-CoV-2 infection in the household (OR = 17.4, 95% CI: 8.3–36.8, p < 0.001). Living with a healthcare professional was not associated with a higher risk of infection (OR = 1.0, 95% CI: 0.4–2.5, p = 0.934). Anosmia/dysgeusia was the symptom with the highest positive predictive value (52.2%, 95% CI: 31.8–72.6, p < 0.001) and specificity (99.3%, 95% CI: 98.9–99.7, p < 0.001), while cough was the most prevalent symptom among SARS-CoV-2 seropositive participants (36%).ConclusionsThe authors observed a SARS-CoV-2 seroprevalence of 2.9% among assessed municipal employees. Anosmia/dysgeusia was the COVID-19 symptom which displayed the highest positive predictive value and specificity.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2022, 35, 3; 297-307
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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