Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "chang, yu" wg kryterium: Autor

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-13 z 13
    Tytuł:
    Artificial Intelligence on the Identification of Beiguan Music
    Autorzy:
    Chang, Yu-Hsin
    Yao, Shu-Nung
    Powiązania:
    https://bibliotekanauki.pl/articles/1945644.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    artificial neural network
    Beiguan music
    music information retrieval
    social tagging
    Opis:
    This research determines an identification system for the types of Beiguan music – a historical, non-classical music genre – by combining artificial neural network (ANN), social tagging, and music information retrieval (MIR). Based on the strategy of social tagging, the procedure of this research includes: evaluating the qualifying features of 48 Beiguan music recordings, quantifying 11 music indexes representing tempo and instrumental features, feeding these sets of quantized data into a three-layered ANN, and executing three rounds of testing, with each round containing 30 times of identification. The result of ANN testing reaches a satisfying correctness (97% overall) on classifying three types of Beiguan music. The purpose of this research is to provide a general attesting method, which can identify diversities within the selected non-classical music genre, Beiguan. The research also quantifies significant musical indexes, which can be effectively identified. The advantages of this method include improving data processing efficiency, fast MIR, and evoking possible musical connections from the high-relation result of statistical analyses.
    Źródło:
    Archives of Acoustics; 2021, 46, 3; 471-478
    0137-5075
    Pojawia się w:
    Archives of Acoustics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The critical trait of digital entrepreneur: mixed methods research
    Autorzy:
    Chuang, Li-Min
    Lee, Yu-Po
    Chang, Yu-Ju
    Powiązania:
    https://bibliotekanauki.pl/articles/2201960.pdf
    Data publikacji:
    2023
    Wydawca:
    Centrum Badań i Innowacji Pro-Akademia
    Tematy:
    digital entrepreneurship
    digital economy
    entrepreneurship
    entrepreneurs
    analytic hierarchy process
    AHP
    przedsiębiorczość cyfrowa
    gospodarka cyfrowa
    przedsiębiorczość
    przedsiębiorcy
    proces hierarchii analitycznej
    Opis:
    Pioneers of the digital era have invented a different business model and expanded the existence of the digital economy, and the digital entrepreneurship is the beginning of this digital revolution. To explore the key characteristics of digital entrepreneurs, this study is divided into two stages. The first stage conducted a literature review and case study to construct the characteristic elements of the entrepreneurship into a model of digital entrepreneurs. In the second stage, the relative weights of the key characteristics of digital entrepreneurs are understood through an analysis of the AHP questionnaire results. The results show that autonomy and selfdiscipline are keys among the main dimensions of the key characteristics of digital entrepreneurs' entrepreneurship; the secondary dimension of "action power" is key in the main dimension of "autonomy and self-discipline"; the secondary dimension of "business networks" is key in the main dimension of "social capital"; the secondary dimension of "insight" is key in the main dimension of "innovation and breakthrough"; the secondary dimension of "communication ability" is key in the main dimension of "leadership communication".
    Źródło:
    Acta Innovations; 2023, 46; 5--18
    2300-5599
    Pojawia się w:
    Acta Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dose-effect relationship on anti-inflammatory activity on LPS induced RAW 264.7 cells and antioxidant activity of rutin in vitro
    Autorzy:
    tian, chunlian
    guo, yuru
    chang, yu
    zhao, jihang
    cui, cancan
    liu, mingchun
    Powiązania:
    https://bibliotekanauki.pl/articles/895707.pdf
    Data publikacji:
    2019-06-28
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    antioxidant
    Anti-inflammatory
    lipopolysaccharide
    rutin
    dose-effect relationship
    Opis:
    Rutin, as a common flavonol glycoside, exists abundantly in many plants and exhibits various nutritional and pharmacological function. Current study focused on the dose-effect relationship of rutin on the anti-inflammatory and antioxidant activities in vitro against LPS-stimulated RAW 264.7 cells and free radicals or ferric-ion. This study evaluated the anti-inflammatory activity by observation cell morphological and determination of the content of NO, TNF-α, IL-1β and IL-6, and the phagocytic activity in LPS induced RAW 264.7 cells; and revealed the antioxidant activities via assay of DPPH radical scavenging capacity, ABTS radical scavenging capacity, and reducing power. The study indicated that 5, 10, 20, 50 and 100 μM of rutin all exhibited a better anti-inflammatory activity, in especial 50 and 100 μM. Meanwhile, it exerted a stronger antioxidant activities than BHT, and equivalent to VC at the same concentration. Combined, the results suggested that rutin will be a potential and important adjuvant in treatment of inflammatory diseases and oxidative stress.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 3; 511-522
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    ANTI-INFLAMMATORY ACTIVITY AND CYTOTOXICITY OF DIOSGENIN ON LIPOPOLYSACCHARIDES INDUCED RAW 264.7 CELLS
    Autorzy:
    ning, jing
    chang, yu
    wang, ruxia
    lan, zhiwei
    ru, qing
    liu, mingchun
    tian, chunlian
    Powiązania:
    https://bibliotekanauki.pl/articles/895615.pdf
    Data publikacji:
    2020-04-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    Diosgenin
    Anti-inflammatory
    lipopolysaccharides
    cytotoxicity
    phagocytosis ability  
    Opis:
    Diosgenin is a steroidal sapogenin compound, and possesses multiple biological activities including anti-inflammatory, anticancer, immunological regulation, and anti-aging. The current study focused on its anti-inflammatory activities and cytotoxicity by analysis of NO production, phagocytosis activity, secretion of TNF-α and IL-6 and cell viability in LPS-induced RAW 264.7 cells. An IC50 value of diosgenin of 2.8 μM was calculated for diosgenin by regression of cell viability from concentrations ranging from 0.01 to 25 μM; this indicated that 0.01, 0.02, 0.04 μM diosgenin could reduce phagocytic activity very significantly (p<0.01) in a dose-dependent manner with no cytotoxic effect on the LPS-induced RAW 264.7 cells. However, there was no significant effect on NO content and secretion of TNF-α and IL-6 after diosgenin treatment. The research revealed that low concentrations diosgenin can directly inhibit cells phagocytosis, with no effect on the release of inflammatory mediators and cytokines. This lays a foundation for screening for a safe dose in research and developent of derivatives and new formulation of diosgenin for its anti-inflammatory effect.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 313-317
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microstructure and Properties of Composite Produced by Vacuum Sintering of Vanadis 4 Extra Steel Powder with Tantalum Carbides and Following Heat Treatment
    Autorzy:
    Huang, Kuo-Tsung
    Chang, Shih-Hsien
    Chuang, Chan-Yu
    Powiązania:
    https://bibliotekanauki.pl/articles/353735.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    tantalum carbide
    Vanadis 4 Extra steel
    transverse rupture strength
    polarization resistance
    sub-zero heat treatment
    Opis:
    In this study, different amounts of tantalum carbide (TaC) powders (5, 10 and 15 wt.%) are added to Vanadis 4 Extra steel powders. The composite powders are sintered at 1260, 1280, 1300, 1320, 1340 and 1360°C for 1 h, respectively. The experimental results showed that good mechanical properties (hardness 79.7 HRA, TRS 2246 MPa) were obtained by the addition of 10% TaC sintered at 1320°C for 1 h. Furthermore, the optimal sintered V4ES/TaC (Vanadis 4 Extra steel / TaC) composites after sub-zero treatment possess the highest hardness (80.9 HRA) and transverse rupture strength (TRS) values (2445 MPa), as well as a better polarization resistance (658.99 Ω·cm2). After sub-zero treatment, the VC carbides decompose and re-precipitate refined VC carbides within the grains (VC carbides are formed in steel powder); moreover, the TaC particles are still uniformly distributed around the grain boundaries, which results in dispersion strengthening and precipitation hardening. The results clearly reveal that sub-zero heat treatment effectively improves the microstructure and strengthens the V4ES/TaC composite.
    Źródło:
    Archives of Metallurgy and Materials; 2020, 65, 2; 555-563
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of Y2O3 on Microstructure and Corrosion Properties of Laser Cladding Composite Coatings on 304 Stainless Steel Substrate
    Autorzy:
    Yu, Jinling
    Zhentai, Zheng
    Li, Shuai
    Guo, Donghui
    Chang, Liang
    Powiązania:
    https://bibliotekanauki.pl/articles/27313865.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    laser cladding
    Ni-based coatings
    electrochemical corrosion
    Opis:
    Ni625/WC composite coatings added with different amounts of Y2O3 were prepared on the surface of 304 stainless steels by laser cladding. This study focused on the microstructure characteristics, microhardness, and corrosion performances of Ni625/WC composite coatings. The results showed that Y2O3 can effectively improve the corrosion resistance of the composite coatings. The microstructure from the bottom to the surface of composite coatings consists of plane crystal, cellular crystal, columnar crystal and equiaxed crystal. The Y2O3 content of optimum composite coating was 1.0%. Its microhardness was three times that of matrix material. In addition, the corrosion current density of the composite coating was only 2% of Ni625/WC coating, which was attributed to the good properties of Y2O3 and appropriate Y2O3 refined microstructure.
    Źródło:
    Archives of Metallurgy and Materials; 2023, 68, 2; 447--453
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation of the Microstructure and Strengthening Mechanisms of Ti-6Cu-8Nb-xCr3C2 Alloy through Vacuum Sintering Process
    Autorzy:
    Chang, Shih-Hsien
    Weng, Chen-Yu
    Huang, Kuo-Tsung
    Liang, Cheng
    Powiązania:
    https://bibliotekanauki.pl/articles/2106558.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    vacuum sintering
    Ti-6Cu-8Nb-Cr3C2 alloy
    hardness
    transverse rupture strength
    EBSD
    Opis:
    This study mixes four different powders to produce Ti-6Cu-8Nb-xCr3C2 (x = 1, 3, and 5 mass%) alloys in three different proportions. The experimental results reveal that when 5 mass% Cr3C2 was added to the Ti-6Cu-8Nb alloys, the specimen possessed optimal mechanical properties after sintering at 1275°C for 1 h. The relative density reached 98.23%, hardness was enhanced to 67.8 HRA, and the transverse rupture strength (TRS) increased to 1821.2 MPa, respectively. The EBSD results show that the added Cr3C2 in situ decomposed into TiC and NbC during the sintering process, and the generated intermetallic compounds (Ti2Cu) were evenly dispersed in the Ti matrix. Furthermore, the reduced Cr atom acts as a β-phase stabilizing element and solid-solution in the Ti matrix. Consequently, the main strengthening mechanisms of the Ti-6Cu-8Nb-xCr3C2 alloys include dispersion strengthening, solid-solution strengthening, and precipitation hardening.
    Źródło:
    Archives of Metallurgy and Materials; 2022, 67, 3; 815--825
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation and calibration of thermal and salinity layering in surface water resources using Ce-Qual-W2 model
    Autorzy:
    Chen, Tzu-Chia
    Yu, Shu-Yan
    Wang, Chang-Ming
    Xie, Sen
    Barazandeh, Hanif
    Powiązania:
    https://bibliotekanauki.pl/articles/2048504.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Technologiczno-Przyrodniczy
    Tematy:
    Ce-Qual-W2 model
    salinity
    surface water
    thermal layering
    water quality modelling
    water resources
    Opis:
    In the discussion of water quality control, the first and most effective parameter that affects other variables and water quality parameters is the temperature situation and water temperature parameters that control many ecological and chemical processes in reservoirs. Additionally, one of the most important quality parameters studied in the quality of water resources of dams and reservoirs is the study of water quality in terms of salinity. The salinity of the reservoirs is primarily due to the rivers leading into them. The control of error in the reservoirs is always considered because the outlet water of the reservoirs, depending on the type of consumption, should always be standard in terms of salinity. Therefore, in this study, using the available statistics, the Ce-Qual-W2 two-dimensional model was used to simulate the heat and salinity layering of the Latyan Dam reservoir. The results showed that with warming and shifting from spring to late summer, the slope of temperature changes at depth increases and thermal layering intensifies, and a severe temperature difference occurs at depth. The results of sensitivity analysis also showed that by decreasing the wind shear coefficient (WSC), the reservoir water temperature increases, so that by increasing or decreasing the value of this coefficient by 0.4, the average water temperature by 0.56°C changes inversely, and the results also show that by increasing or decreasing the value of the shade coefficient by 0.85, the average water temperature changes by about 7.62°C, directly.
    Źródło:
    Journal of Water and Land Development; 2021, 51; 117-123
    1429-7426
    2083-4535
    Pojawia się w:
    Journal of Water and Land Development
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cooperative adaptive driving for platooning autonomous self driving based on edge computing
    Autorzy:
    Chang, Ben-Jye
    Hwang, Ren-Hung
    Tsai, Yueh-Lin
    Yu, Bo-Han
    Liang, Ying-Hsin
    Powiązania:
    https://bibliotekanauki.pl/articles/330778.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    mobile edge computing
    active safe driving
    cooperative platoon driving
    cooperative adaptive cruise control
    przetwarzanie mobilne
    bezpieczna jazda
    tempomat adaptacyjny
    Opis:
    Cooperative adaptive cruise control (CACC) for human and autonomous self-driving aims to achieve active safe driving that avoids vehicle accidents or traffic jam by exchanging the road traffic information (e.g., traffic flow, traffic density, velocity variation, etc.) among neighbor vehicles. However, in CACC, the butterfly effect is encountered while exhibiting asynchronous brakes that easily lead to backward shock-waves and are difficult to remove. Several critical issues should be addressed in CACC, including (i) difficulties with adaptive steering of the inter-vehicle distances among neighbor vehicles and the vehicle speed, (ii) the butterfly effect, (iii) unstable vehicle traffic flow, etc. To address the above issues in CACC, this paper proposes the mobile edge computing-based vehicular cloud of the cooperative adaptive driving (CAD) approach to avoid shock-waves efficiently in platoon driving. Numerical results demonstrate that the CAD approach outperforms the compared techniques in the number of shock-waves, average vehicle velocity, average travel time and time to collision (TTC). Additionally, the adaptive platoon length is determined according to the traffic information gathered from the global and local clouds.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2019, 29, 2; 213-225
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effort-reward imbalance and job strain index associated with health-related quality of life for civil servants in a national survey: the mediation effect of job support and over-commitment
    Autorzy:
    Tseng, Po-Chang
    Lin, Ping-Yi
    Liang, Wen-Miin
    Lin, Wen-Yu
    Kuo, Hsien-Wen
    Powiązania:
    https://bibliotekanauki.pl/articles/2085738.pdf
    Data publikacji:
    2022-08-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    job strain
    civil servants
    mediation analysis
    health-related quality of life
    effort-reward imbalance
    job support
    Opis:
    ObjectivesWork-related stress (WRS) is significantly associated with health-related quality of life (HRQoL), but the amounts of evidence on differences of effort-reward imbalance (ERI) and job strain index (JSI) remain sparse and have limited generalizability. Therefore, we aimed to assess the association between ERI and JSI with HRQoL and assess the mediation effect of social support (JS) and over-commitment (OC) on this association in Taiwan’s civil servants.Material and MethodsA cross-sectional national survey was given to registered civil servants in Taiwan – 20 046 civil servants from 647 institutions were enrolled using multistage stratified random cluster sampling. A web-questionnaire collected demographic information, job characteristics, and different indexes of ERI and job-control-demand-support (JCDS) models. Structural equation model (SEM) was used to examine the association between ERI and JSI with HRQoL, and the mediation effect of JS and OC on the associations.ResultsIn the ERI model, ERI and OC were consistently negatively associated with the mental component score (MCS) (r = –0.46 and r = –0.37) and physical component score (PCS) (r = –0.45 and r = –0.34), which were higher than job demand (r = –0.28 and r = –0.22) and JSI (r = –0.38 and r = –0.29). Using hierarchical multiple regression analyses, ERI was significantly correlated with MCS and PCS, which was consistently higher than JSI. The ERI and JSI were significantly correlated with MCS (β = –0.170 and β = –0.140) and PCS (β = –0.150 and β = –0.082) using SEM analysis, whereas ERI was considerably higher than in JSI. In addition, OC and JS mediated the association between The ERI and JSI with HRQoL.ConclusionsWe found the ERI index is significantly correlated with HRQoL superior to JSI, in particular among Taiwan civil servants. Further longitudinal studies are needed to determine the causality and spatiotemporal relation of these differences.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2022, 35, 4; 425-436
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and Theoretical Studies of a New Insensitive Explosive, 2’-Methyl-3-nitro-2’H-[1,3’-bi(1,2,4-triazole)]-5,5’-diamine
    Autorzy:
    Luo, J.
    Liu, Y.
    Wang, J.
    Chai, T.
    Yuan, J.
    Chang, S.
    Yu, Y.
    Jing, S.
    Ma, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/358633.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
    Tematy:
    insensitive explosive
    synthesis
    theoretical studies
    density functional theory
    new 1,2,4-triazole derivative
    Opis:
    A new insensitive energetic material 2’-methyl-3-nitro-2’H-[1,3’-bi(1,2,4-triazole)]-5,5’-diamine (1) was prepared by a three-step synthesis from commercially available chemicals. The energetic title compound was comprehensively characterized by various means, including FT-IR, multinuclear (1H, 13C, 14N) NMR spectroscopy, elemental analysis, HPLC and thermal analysis. The sensitivities of the synthesized material towards various external stimuli (impact, friction) were determined according to the BAM method. The optimized structure and related thermodynamic parameters were obtained at the DFT-B3LYP/6-31+G** theoretical level. The detonation properties of the material were also predicted according to the Kamlet-Jacobs formulae and the Monte-Carlo method. The results show that the density, heat of formation, detonation velocity, detonation pressure, impact sensitivity and purity were 1.83 g/cm3, 369 kJ/mol, 7.52 km/s, 25.4 GPa, 82.3 J and 97.7%, respectively. In addition, the compound was an insensitive high explosive which could meet the requirements of high energetic materials.
    Źródło:
    Central European Journal of Energetic Materials; 2017, 14, 2; 269-280
    1733-7178
    Pojawia się w:
    Central European Journal of Energetic Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Entry into vocational rehabilitation program following work-related hand injury: Potential candidates
    Autorzy:
    Chen, Yueh-Hsia
    Hsu, Chung-Yin
    Lien, Shwu-Huei
    Yu, Shu-Jung
    Chang, Jen-Mu
    Su, Shanq-Wen
    Chao, Yuan-Hung
    Powiązania:
    https://bibliotekanauki.pl/articles/2177083.pdf
    Data publikacji:
    2015-09-23
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    rehabilitation
    vocational
    return to work
    occupational injuries
    hand injuries
    Opis:
    Objectives This case-control study aimed to investigate the predictors of return to work (RTW) following work-related major forearm, wrist or hand injury at the preparation stage of return to work. Material and Methods A total of 80 clients were recruited and divided into 2 groups depending on their readiness of RTW. The groups were compared with each other with regard to their demographics, compensation status, hand injury severity, health perception, and time off work (TOW) using correlation coefficient. Predictors of RTW were measured by logistic regression analysis. Results There were no significant differences in demographics and the severity of hand injury between 2 groups. Self-perceived physical functioning (p = 0.04), vitality (p = 0.01), mental health (p = 0.03) and TOW (p = 0.001) were significantly different between Action group and Preparation group. With binary logistic regression analysis, self-perceived vitality (odds ratio (OR) = 1.041) and TOW (OR = 0.996) were shown to be strongly predictive of RTW at the preparation stage of return to work. Conclusions This study has shown that shorter TOW and better self-perceived vitality could predict early readiness for RTW after major work-related forearm, wrist or hand injury.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2016, 29, 1; 101-111
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ezetimibe prevents myocardial remodeling in an obese rat model by inhibiting inflammation
    Autorzy:
    Li, Xiao-Xing
    Zhao, Lang
    Chang, Ying
    Liu, Bao-Shan
    Xu, Feng
    Zhang, Cheng
    Ji, Xiao-Ping
    Chen, Yu-Guo
    Li, Chuan-Bao
    Powiązania:
    https://bibliotekanauki.pl/articles/1038380.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    obese
    inflammation
    remodeling
    ezetimibe
    IL-6
    Opis:
    Inflammation plays an important role in the development of many obesity-related diseases. This study aimed to investigate the effect of ezetimibe on inflammation and myocardial remodeling in obese rats. A rat model of obesity was established, and myocardial damage was examined by transmission electron microscopy and Masson staining. Twenty obese rats were divided into two groups (n=10): obese group and ezetimibe group. Ten SD rats were used as controls. Western blot was performed to monitor the expression of P-p38MAPK and interleukin (IL)-6. Immunohistochemical staining was used to monitor the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. In the obese rats group, we observed increased inflammatory factors and myocardial hypertrophy. In contrast, the ezetimibe group exhibited decreased expression of inflammatory factors and an improvement in myocardial remodeling compared to the obese group. Mechanistically, we found that ezetimibe decreased P-p38MAPK, IL-6, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 levels in the hearts of the obese rats. Taken together, these results indicate that ezetimibe may improve myocardial remodeling in obese rats by inhibiting inflammation.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 3; 465-470
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-13 z 13

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies