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Tytuł:
Preparation of scutellarin loaded TPGS polymeric micelles and evaluation of its pharmacokinetics and pharmacodynamics effects in rats
Autorzy:
Zou, Liu
Xiong, Shujuan
Deng, Xiangping
Liu, Juan
Xiong, Runde
Wang, Zhe
Cao, Xuan
Chen, Yanming
Guo, Yu
Tang, Guotao
Powiązania:
https://bibliotekanauki.pl/articles/895637.pdf
Data publikacji:
2018-12-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
scutellarin
TPGS
polymeric micelles
antithrombotic drugs
Opis:
To improve the clinical effect of scutellarin by extending the action time in vivo, scutellarin loaded polymeric micelles were developed by D-alpha tocopherol polyethylene glycol 1000 succinate (Scu/TPGS). Scu/TPGS were prepared using film solvent diffusion methods and characterized on the basis of their particle size, zeta potential, and drug encapsulation efficiency. Dynamic dialysis was used to study the release behavior of the polymeric micelles in vitro. Its pharmacokinetic characteristics and antithrombotic efficacy were studied by intravenous injection in rats. The results showed that Scu/TPGS were spherical, 20.09±2.62 nm in size and a slow release in vitro. The pharmacokinetic parameter T1/2 of Scu/TPGS was 762.12±46.56 min compared with commercial injection of 59.30±10.67 min (p<0.05). At the 1 mg/kg dose, the thrombolysis effect of micellar group was stronger than that of the commercial group (p<0.05). In conclusion, TPGS polymer micelles provided a valid strategy in chemotherapy for cerebrovascular diseases with poor water solubility and poor lipid solubility drugs such as scutellarin.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1305-1312
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Adsorption of lead ion on the hydrated rutile (110) surface: a DFT calculation study
Autorzy:
Zou, Heng
Cao, Qinbo
Chen, Xiumin
Liu, Dianwen
Powiązania:
https://bibliotekanauki.pl/articles/109829.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
rutile
hydrated surface
lead ion
adsorption
density functional theory
Opis:
The adsorption behavior of lead species on the hydrated rutile surface was investigated with inductively coupled plasma mass spectrometry (ICP-MS) measurements and density functional theory (DFT) calculations. ICP-MS experiments suggested that lead species can be readily absorbed by the rutile powder in water at pH 6.5. From the ICP-MS results and the species distribution of Pb2+, it was concluded that Pb2+ was the major lead species adsorbing at the rutile/water interface at the pH of 6.5. DFT calculation results indicated that Pb2+ could adsorb at four different sites on the surface. At each site, water molecules or OH groups were involved in the reaction with Pb2+. The water molecules/OH groups on the rutile surface play an important role during the adsorption of Pb2+ on the hydrated rutile surface.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 4; 951-959
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thermal performance analysis of manned airships in a thermally variable environment
Autorzy:
Shi, Hong
Liu, Meinan
Chen, Jiamin
Zou, Yitao
Powiązania:
https://bibliotekanauki.pl/articles/2173708.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
manned airship
thermal performance
nacelle
temperature difference
flight position
sterowiec załogowy
wydajność cieplna
gondola
różnica temperatur
pozycja lotu
Opis:
The safety and reliability of the manned airship depend to a considerable extent on its thermal performance. In this paper, heat balance equations are developed and solved in the C++ programming language. The temperature variation of the enclosure, gasbag, and nacelles of the manned airship is investigated. In addition, the effects of season, latitude, and orientation on the thermal performance of the manned airship and the airship nacelle are investigated. The results show that: (1) The average temperature difference of the nacelle surface at the same time is 25 K, while the maximum temperature difference in the nacelle is 29 K during the day, (2) the temperature distribution in the nacelle is similar in spring and autumn, with maximum temperature between 306 K and 309 K. The maximum temperature in the nacelle is between 300 K and 303 K in winter while the maximum temperature in the nacelles is between 309 K and 315 K in summer, (3) as the flight position of the manned airship changes from 20°N to 60°N, the average nacelle temperature varies slightly by about 1 K. However, as the latitude increases, the high- temperature region shifts from the bottom of the nacelle to the side of the nacelle, and (4) the temperature distribution of the upper envelope of the airship varies considerably with orientation. However, the average temperature of the nacelle is less impacted by orientation. These results are useful for understanding the thermal performance of manned airships.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2022, 70, 5; art. no. e143105
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Subsynchronous oscillation and its mitigation of VSC-MTDC with doubly-fed induction generator-based wind farm integration
Autorzy:
Su, Miaohong
Dong, Maiying
Liu, Kaiqi
Zou, Weiwei
Powiązania:
https://bibliotekanauki.pl/articles/1841370.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
doubly-fed induction generator
eigenvalue analysis
multi-channel variable-parameter subsynchronous damping controller
subsynchronous oscillation voltage source converter
multi-terminal direct current transmission system
Opis:
Wind power integration through the voltage source converter-based high-voltage direct current (VSC-HVDC) system will be a potential solution for delivering large-scalewind power to the “Three-North Regions” of China. However, the interaction between the doubly-fed induction generator (DFIG) and VSC-HVDC system may cause the risk of subsynchronous oscillation (SSO). This paper establishes a small-signal model of the VSC based multi-terminal direct current (VSC-MTDC) system with new energy access for the problem, and the influencing factors causing SSO are analyzed based on the eigen valueanalysis method. The theoretical analysis results show that the SSO in the system is related to the wind farm operating conditions, the rotor-side controller (RSC) of the DFIG and the interaction of the controller in the VSC-MTDC system. Then, the phase lag characteristicis obtained based on the signal test method, and a multi-channel variable-parameter subsynchronous damping controller (SSDC) is designed via selecting reasonable parameters.Finally, the correctness of the theoretical analysis and the effectiveness of the multi-channelvariable-parameter SSDC are verified based on time-domain simulation.
Źródło:
Archives of Electrical Engineering; 2021, 70, 1; 53-72
1427-4221
2300-2506
Pojawia się w:
Archives of Electrical Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Binding features of N-hexadecanoylglycine on two terminations of fluorapatite (001) surface and their effect on fluorapatite flotation
Autorzy:
Zou, Heng
Liu, Dianwen
Cao, Qinbo
Chen, Xiumin
Powiązania:
https://bibliotekanauki.pl/articles/1845208.pdf
Data publikacji:
2020
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
fluorapatite
adsorption
amino acid-based collector
density functional theory
Opis:
N-hexadecanoylglycine (C16Gly) is a newly synthesized collector, which can be used as an efficient collector for fluorapatite (FA) rather than for dolomite. To extend our knowledge regarding the C16Gly collector, the contact angle method was employed to understand the flotation selectivity of C16Gly in the FA and dolomite system. On the other hand, the possible binding models of C16Gly anion on Ca-rich and PO4-rich terminations of FA (001) surface were investigated with density functional theory calculations to reveal the interaction between the C16Gly and the FA surface. Results showed that C16Gly anion could interact with these two terminations to generate 12 low-energy configurations, including bidentate, tridentate and chelating binding models. The C16Gly anion preferred to adsorb onto the Ca-rich termination, which is caused by the weaker electrostatic repulsion force between the C16Gly anion and the PO4 groups on this termination. The adsorption of C16Gly on these terminations was more stable than that on the dolomite (104) surface, which is one of the reasons for the preferential flotation of FA from dolomite using C16Gly as a collector. These findings provide further insights into the selectivity of C16Gly during the flotation of FA and dolomite.
Źródło:
Physicochemical Problems of Mineral Processing; 2020, 56, 5; 949-959
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of cadmium stress on root tip cells and some physiological indexes in Allium cepa var. agrogarum L.
Autorzy:
Zou, J.
Yue, J.
Jiang, W.
Liu, D.
Powiązania:
https://bibliotekanauki.pl/articles/19550.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Allium cepa var. agrogarum L. seedlings grown in nutrient solution were subjected to increasing concentrations of Cd2+ (0, 1, 10, 100 μM). Variation in tolerance to cadmium toxicity was studied based on chromosome aberrations, nucleoli structure and reconstruction of root tip cells, Cd accumulation and mineral metabolism, lipid peroxidation, and changes in the antioxidative defense system (SOD, CAT, POD) in leaves and roots of the seedlings. Cd induced chromosome aberrations including C-mitoses, chromosome bridges, chromosome fragments and chromosome stickiness. Cd induced the production of some particles of argyrophilic proteins scattered in the nuclei and even extruded from the nucleoli into the cytoplasm after a high Cd concentration or prolonged Cd stress, and nucleolar reconstruction was inhibited. In Cd2+-treated Allium cepa var. agrogarum plants the metal was largely restricted to the roots; very little of it was transported to aerial parts. Adding Cd2+ to the nutrient solution affected mineral metabolism. For example, at 100 μM Cd it reduced the levels of Mn, Cu and Zn in roots, bulbs and leaves. Malondialdehyde content in roots and leaves increased with treatment time and increased concentration of Cd. Antioxidant enzymes appear to play a key role in resistance to Cd under stress conditions.
Źródło:
Acta Biologica Cracoviensia. Series Botanica; 2012, 54, 1
0001-5296
Pojawia się w:
Acta Biologica Cracoviensia. Series Botanica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Laser Welding of TA15 Titanium Alloy and Inconel 718 Dissimilar Metals
Autorzy:
An, Qi
Wu, Dongting
Liu, Peng
Zou, Yong
Powiązania:
https://bibliotekanauki.pl/articles/2174556.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
TA15 titanium alloy
Inconel 718 nickel-based alloy
laser welding
microstructure
tensile strength and fracture characteristic
Opis:
This paper studied the effect of laser welding technology on dissimilar metal welding joints of TA15 titanium alloy and Inconel 718 nickel-based alloy. The research results indicate that the laser welding of TA15 titanium alloy and Inconel 718 nickel-based alloy directly was difficult to form well, which due to the intermetallic compounds caused the joint brittle. When the pure Cu foil was used as the filling layer, the quality of the welding joints can be improved effectively. The experimental results also indicate that there were brittle intermetallic-compounds in the laser welding seam, and the laser power had an important influence on the performance and mechanical properties of the dissimilar metal joint. The maximum average tensile strength of the welding joint of 2300 W was increased to 252.32 MPa. Scanning electron microscope(SEM) results show that the fracture morphology was river pattern, a typical morphological of cleavage fracture, and the mode was brittle fracture.
Źródło:
Archives of Metallurgy and Materials; 2022, 67, 4; 1267--1276
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Die Wall Lubrication on High Velocity Compaction Behavior and Sintering Properties of Fe-Based PM Alloy
Autorzy:
Liu, Zili
Li, Dong
Liu, Xiqin
Li, Haohao
Huang, Xin
Tang, Zhihao
Zou, Yuwen
Powiązania:
https://bibliotekanauki.pl/articles/352101.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
high velocity compaction
die wall lubrication
green density
impact force
cold welding
Opis:
Fe-based PM alloy powder of Fe-2.5Ni-0.5Mo-2Cu-0.4C was pressed by high velocity compaction combined with die wall lubrication, and the effect of die wall lubrication on high velocity compaction behavior and sintering properties of the Fe-based PM alloy were studied. The results indicate that the impact force, green density, sintered density of samples increase with the augment of the impact velocity and die wall lubrication. Compared with that without die wall lubrication, the green density and sintered density of the sample with die wall lubrication are about 0.07-0.12 g/cm3 and 0.08~0.11 g/cm3 higher at the same impact velocity, respectively, while the ejection force of the die wall lubricated sample is much smaller, and reduced about 26%~36%. The green compact with die wall lubrication has much fewer porosity than that without die wall lubrication, and more mechanical bonding and cold welding regions are observed. The sintered samples mainly consists of gray pearlite and white ferrite, and more pearlite is observed in the sintered sample with die wall lubrication.
Źródło:
Archives of Metallurgy and Materials; 2020, 65, 2; 677-684
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Electromagnetic Wave Absorbing Properties of Cotton Fabric with Carbon Nanotubes Coating
Właściwości pochłaniania fal elektromagnetycznych tkaniny bawełnianej z powłoką z nanorurek węglowych
Autorzy:
Zou, Lihua
Shen, Jiahui
Xu, Zhenzhen
Ruan, Fangtao
Qiu, Yiping
Liu, Zhi
Powiązania:
https://bibliotekanauki.pl/articles/232586.pdf
Data publikacji:
2020
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
carbon nanotube
electromagnetic wave
absorbing
coating
cotton fabric
nanorurka węglowa
fala elektromagnetyczna
pochłanianie
powłoka
tkanina bawełniana
Opis:
In order to endow cotton fabric with the electromagnetic shielding property while preserving comfort and softness, carbon nanotubes (CNTs) were coated onto NaOH pretreated fabrics via a binder-free dip-coating approach. Scanning electron microscopy (SEM) and Infrared spectroscopy were utilised to investigate the surface morphology and modification of the CNT functionalised fabrics. The effects of the number of dip-coatings, the concentration of carbon nanotubes, and the impregnation temperature on electrical conductivity, electromagnetic (EM) shielding effectiveness (SE), and wave absorbing efficiency of cotton fabrics were evaluated, respectively. The SE value of the CNT functionalised cotton fabrics increased with the dip-coating time and reached 16.5 dB after CNT dip-coating ten times, which indicates that 97.76% of the electromagnetic wave was shielded. Meanwhile, by adding layers of stacking fabrics, the SE of CNT coated fabrics was further improved to 26.4 dB. The shielding mechanism was also studied by comparing its reflection and absorption behaviour, which demonstrates that 65.7% of the electromagnetic wave was absorbed.
Aby nadać tkaninie bawełnianej właściwości ekranowania elektromagnetycznego przy jednoczesnym zachowaniu komfortu i miękkości, najpierw zastosowano obróbkę tkaniny z zastosowaniem NaOH, a następnie nałożono na nią powłokę z nanorurek węglowych (CNT). Za pomocą skaningowej mikroskopii elektronowej (SEM) i spektroskopii w podczerwieni zbadano morfologię powierzchni tkanin funkcjonalizowanych CNT. Oceniono wpływ liczby powłok zanurzeniowych, stężenia nanorurek węglowych i temperatury impregnacji na przewodność elektryczną, skuteczność ekranowania elektromagnetycznego (EM) (SE) oraz efektywność pochłaniania fal przez tkaniny bawełniane. Stwierdzono, że wartość SE funkcjonalizowanych tkanin bawełnianych CNT wzrastała wraz z czasem powlekania zanurzeniowego i osiągnęła 16.5 dB po dziesięciokrotnym powlekaniu zanurzeniowym CNT, co wskazało, że 97.76% fali elektromagnetycznej było ekranowane. Poprzez dodanie warstw tkanin, współczynnik SE tkanin powlekanych CNT został dodatkowo poprawiony do 26,4 dB. Zbadano również mechanizm ekranowania, porównując jego właściwości odbijania oraz pochłaniania i stwierdzono, że 65.7% fali elektromagnetycznej zostało zaabsorbowane.
Źródło:
Fibres & Textiles in Eastern Europe; 2020, 5 (143); 82-90
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vitro co-stimulation of anti-tumor activity by soluble B7 molecules
Autorzy:
He, Wei
Hu, Zhong-Bo
Liu, Fang
Feng, Xian-Qi
Zou, Ping
Powiązania:
https://bibliotekanauki.pl/articles/1041178.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
immunotherapy
tumor escape
gene fusion
recombinant fusion proteins
Opis:
In order to investigate the anti-tumor activity of a soluble B7-1/immunoglobulin G fusion protein and explore an effective method to eliminate immune escape of tumor cells, a recombinant vector encoding this fusion protein was constructed and constitutively expressed in Chinese hamster ovary cells. After purification with protein G affinity chromatography, the soluble fusion protein was tested for bioactivity. Results showed that the fusion protein could significantly increase the density of B7-1 molecules on WEHI-3 cells, a mouse leukemia cell line. Through allogeneic mixed lymphocyte tumor cultures, it was demonstrated that, with the presence of the first signal, it could also significantly enhance T cell activation and killing activity against WEHI-3 cells and interleukin-2 secretion by activated mouse T lymphocytes. The conclusion can be drawn that the soluble B7-IgG fusion protein has a potent capacity to generate or enhance anti-tumor immune response in vitro, and its clinical value deserves further investigation.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 807-813
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An installation angle error calibration method in an Ultra-Short Baseline system based on a dual transponder
Autorzy:
Liu, Baoheng
Zhang, Xiaochuan
Jia, Shuyang
Zou, Sichen
Tian, Deyan
Da, Lianglong
Powiązania:
https://bibliotekanauki.pl/articles/32921617.pdf
Data publikacji:
2023
Wydawca:
Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Tematy:
USBL
installation angle error
misalignment calibration
numerical algorithm
hydrolocation
Opis:
The installation error of an acoustic transceiver array is one of the important error sources in an ultra-short baseline (USBL) system. In a USBL system with a positioning accuracy of 0.5%, an installation error angle of 1 will lead to a positioning error of 1.7% times the slant distance. In this paper, a dual transponder-based installation angle error calibration method for USBL is proposed. First, the positioning errors induced by various installation angles are deduced and analysed using the linear measurement of seafloor targets. Then, an iterative algorithm is proposed that estimates the rolling alignment error, pitching alignment error, and heading alignment error, in that order. The simulation and experienced results show that, after three iterations, the estimates of the three alignment errors can converge quickly, all of the estimates converge to within 0.001 and the estimated values are very close to the true values. The horizontal positioning error caused by the installation error angle can be reduced by nearly 75%. The method has good effectiveness and robustness, and can greatly improve the positioning accuracy of the USBL system.
Źródło:
Polish Maritime Research; 2023, 2; 121-129
1233-2585
Pojawia się w:
Polish Maritime Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simultaneous extraction of vanadium and chromium from vanadium slag using low-pressure liquid phase oxidation method
Autorzy:
Xia, J.-P.
Zheng, S.-L.
Wang, S.-N.
Liu, B.
Zou, X.
Powiązania:
https://bibliotekanauki.pl/articles/110818.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
vanadium slag
low pressure leaching
liquid phase oxidation
kinetics
Opis:
A low-pressure liquid oxidation method was proposed and proven to be effective to extract vanadium and chromium simultaneously from the vanadium slag in concentrated NaOH aqueous solutions. The effect of temperature, NaOH mass concentration, liquid-to-solid mass ratio, stirring speed and pressure on the extraction of vanadium and chromium in NaOH aqueous solutions were systematically investigated. Under the optimal reaction conditions (temperature of 473 K, liquid-to-solid mass ratio of 6:1, stirring speed of 700 rpm, NaOH mass concentration of 50%, pressure of 1 MPa and reaction time of 180 min), the vanadium and chromium recovery reached 95% and 90%, respectively. It was found that the reaction temperature and NaOH concentration were important factors for the extraction of vanadium and chromium. The kinetics of the decomposition of vanadium slag in concentrated NaOH aqueous under low pressure was analyzed using the shrinking core model, and the results indicated that the extraction of vanadium and chromium were both governed by the internal diffusion step, with apparent activation energies calculated to be 26.22 and 32.79 kJ/mol, respectively.
Źródło:
Physicochemical Problems of Mineral Processing; 2018, 54, 2; 609-619
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Numerical study on the dynamic response of a concrete filled steel tubular long column under axial impact by a rigid-body
Autorzy:
Qi, Han
Chen, Shuohui
Zou, Jianlei
Zhang, Huidi
Liu, Mengsha
Ju, Jinsan
Sang, Xiuxing
Powiązania:
https://bibliotekanauki.pl/articles/2055059.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
concrete filled steel tubular long column
rigid body
impact load
dynamic response
Opis:
In this study, refined finite element models of concrete filled steel tubular long columns with length diameter ratio (L/D) of 50 were established, and their dynamic responses under a rigid-body impact were explored. It is found that the form of impact load is only related to and can be predicted from the impact velocity of the rigid-body. The change of axial stress and strain with time is synchronous with that of the impact load. Furthermore, the variation characteristics of axial stress and strain with time are mainly related to the initial velocity of the rigid-body.
Źródło:
Journal of Theoretical and Applied Mechanics; 2021, 59, 4; 551--563
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Seepage process on weathered crust elution-deposited rare earth ores with ammonium carboxylate solution
Autorzy:
Zou, Hualiang
Zhang, Zhenyue
Chen, Zhuo
Liu, Defeng
Chai, Xiuwei
Zhang, Han
Chi, Ru-an
Powiązania:
https://bibliotekanauki.pl/articles/1449672.pdf
Data publikacji:
2020
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
permeability
weathered crust elution-deposited rare earth ore
ammonium carboxylate
hydrodynamics
Opis:
In order to reveal the seepage law of ammonium carboxylate solution in the in-situ leaching process of weathered crust elution-deposited rare earth ores, the effects of concentration, pH, temperature, particle size and porosity on permeability were discussed in this paper. The results shown that the seepage of the leaching agent solutions in the rare earth ore follows Darcy's law and displays a laminar flow under the conditions of this experiment and seepage velocity can be increased by changing leaching conditions. The permeability coefficients are inversely proportional to concentrations of ammonium acetate, ammonium tartrate and ammonium citrate whose concentration is greater than 0.7wt%, because the insoluble complexes formed by the reaction of ammonium citrate with RE3+ at lower concentration n decrease the permeability coefficient. The permeability coefficients of ammonium carboxylate solutions increase firstly and then decrease with the pH increased. The maximum of permeability coefficients of ammonium acetate, ammonium tartrate and ammonium citrate solution were 2.92, 1.91 and 2.70, respectively, while the pH of solution were 5, 6 and 7, respectively. Increasing temperature is beneficial for the seepage of ammonium carboxylate solution in orebody, therefore, it is helpful for leaching operation in summer. Moreover, clay minerals particle size and porosity are the key factors affecting the permeability of ammonium carboxylate solution in orebody. The permeability coefficients of ammonium acetate, ammonium tartrate and ammonium citrate solutions are 2.92×104cm/s,1.90×10-4cm/s and 2.69×10-4cm/s, respectively, at the same temperature of 293K, original particle size and porosity of the ore. Ammonium acetate solution has the best permeability in orebody.
Źródło:
Physicochemical Problems of Mineral Processing; 2020, 56, 1; 89-101
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Isolation and expression pattern of RGS21 gene, a novel RGS member
Autorzy:
Li, Xin
Chen, Lei
Ji, Chaoneng
Liu, Bing
Gu, Jiefeng
Xu, Jian
Zou, Xianqiong
Gu, Shaohua
Mao, Yumin
Powiązania:
https://bibliotekanauki.pl/articles/1041351.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
RGS21
G-protein signaling pathway
G-protein α subunit (Gα)
Opis:
Regulators of G-protein signaling (RGS) proteins are known for the RGS domain that is composed of a conserved stretch of 120 amino acids, which binds directly to activated G-protein α subunits and acts as a GTPase-activating protein (GAP), leading to their deactivation and termination of downstream signals. In this study, a novel human RGS cDNA (RGS21), 1795 bp long and encoding a 152-amino acid polypeptide, was isolated by large-scale sequencing analysis of a human fetal brain cDNA library. Unlike other RGS family members, RGS21 gene has no additional domain/motif and may represent the smallest known member of RGS family. It may belong to the B/R4 subfamily, which suggests that it may serve exclusively as a negative regulator of αi/o family members and/or αq/11. PCR analysis showed that RGS21 mRNA was expressed ubiquitously in the 16 tissues examined, implying general physiological roles.
Źródło:
Acta Biochimica Polonica; 2005, 52, 4; 943-946
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł

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