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Tytuł:
Investigation of the toxicity of the ionic liquid 1-butyl-3-methylimidazolium chloride to Saccharomyces cerevisiae AY93161 for lignocellulosic ethanol production
Autorzy:
Zhu, Shengdong
Yu, Pei
Lei, Mingke
Tong, Yanjie
Zheng, Lu
Zhang, Rui
Ji, Jun
Chen, Qiming
Wu, Yuanxin
Powiązania:
https://bibliotekanauki.pl/articles/778529.pdf
Data publikacji:
2013
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
Ionic liquid
[bmim]Cl
toxicity
Saccharomyces cerevisiae AY93161
lignocellulosic ethanol production
Opis:
Ionic liquid (IL) pretreatment of lignocellulosic materials has provided a new technical tool to improve lignocellulosic ethanol production. To evaluate the influence of the residual IL in the fermentable sugars from enzymatic hydrolysis of IL pretreatment of lignocellulosic materials on the subsequent ethanol fermentation, the toxicity of the IL 1-butyl-3-methylimidazolium chloride ([BMIM]Cl) to Saccharomyces cerevisiae AY93161 was investigated. Firstly, the morphological structure, budding and metabolic activity of Saccharomyces cerevisiae AY93161 at different [BMIM]Cl concentrations were observed under an optical microscope. The results show that its single cell morphology remained unchanged at all [BMIM]Cl concentrations, but its reproduction rate by budding and its metabolic activity decreased with the [BMIM]Cl concentration increasing. The half effective concentration (EC50) and the half inhibition concentration (IC50) of [BMIM]Cl to Saccharomyces cerevisiae AY93161 were then measured using solid and liquid suspension culture and their value were 0.53 and 0.39 g.L-1 respectively. Finally, the influence of [BMIM]Cl on ethanol production was investigated. The results indicate that the [BMIM]Cl inhibited the growth and ethanol production of Saccharomyces cerevisiae AY93161. This toxicity study provides useful basic data for further development in lignocellulosic ethanol production by using IL technology and it also enriches the IL toxicity data.
Źródło:
Polish Journal of Chemical Technology; 2013, 15, 2; 94-98
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Existence Of P≥3-Factor Covered Graphs
Autorzy:
Zhou, Sizhong
Wu, Jiancheng
Zhang, Tao
Powiązania:
https://bibliotekanauki.pl/articles/31341575.pdf
Data publikacji:
2017-11-27
Wydawca:
Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
Tematy:
P≥3-factor
P≥3-factor covered graph
toughness
isolated toughness
regular graph
Opis:
A spanning subgraph F of a graph G is called a P≥3-factor of G if every component of F is a path of order at least 3. A graph G is called a P≥3-factor covered graph if G has a P≥3-factor including e for any e ∈ E(G). In this paper, we obtain three sufficient conditions for graphs to be P≥3-factor covered graphs. Furthermore, it is shown that the results are sharp.
Źródło:
Discussiones Mathematicae Graph Theory; 2017, 37, 4; 1055-1065
2083-5892
Pojawia się w:
Discussiones Mathematicae Graph Theory
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Optimal expression and purification of sapelovirus A structural protein VP1, and its immunogenicity in mice
Autorzy:
Zhao, T.T.
Cui, L.
Chen, L.
Li, J.J.
Liang, Q.L.
Wu, P.J.
Yu, X.Q.
Zhang, Z.H.
Hua, X.G.
Powiązania:
https://bibliotekanauki.pl/articles/2087686.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sapelovirus A
prokaryotic expression
purification
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 3; 573-579
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Feasibility study of RANS in predicting propeller cavitation in behind-hull conditions
Autorzy:
Zhang, Yuxin
Wu, Xiao-ping
Lai, Ming-yan
Zhou, Guo-ping
Zhang, Jie
Powiązania:
https://bibliotekanauki.pl/articles/1573849.pdf
Data publikacji:
2020
Wydawca:
Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Tematy:
RANS
Computational Fluid Dynamics (CFD)
propeller cavitation
turbulence model
grid sensitivity
Opis:
The propeller cavitation not only affects the propulsive efficiency of a ship but also can cause vibration and noise. Accurate predictions of propeller cavitation are crucial at the design stage. This paper investigates the feasibility of the Reynolds-averaged Navier–Stokes (RANS) method in predicting propeller cavitation in behind-hull conditions, focusing on four aspects: (i) grid sensitivity; (ii) the time step effect; (iii) the turbulence model effect; and (iv) ability to rank two slightly different propellers. The Schnerr-Sauer model is adopted as the cavitation model. A model test is conducted to validate the numerical results. Good agreement on the cavitation pattern is obtained between the model test and computational fluid dynamics. Two propellers are computed, which have similar geometry but slightly different pitch ratios. The results show that RANS is capable of correctly differentiating the cavitation patterns between the two propellers in terms of the occurrence of face cavitation and the extent of sheet cavitation; moreover, time step size is found to slightly affect sheet cavitation and has a significant impact on the survival of the tip vortex cavitation. It is also observed that grid refinement is crucial for capturing tip vortex cavitation and the two-equation turbulence models used – realizable k-ε and shear stress transport (SST) k-ω – yield similar cavitation results.
Źródło:
Polish Maritime Research; 2020, 4; 26-35
1233-2585
Pojawia się w:
Polish Maritime Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Critical Conditions and Kinetics Required for Dynamic Recrystallization in a High-Carbon Tool Steel
Autorzy:
Zhang, Yong-Ji
Wu, Guang-Lian
Wu, Shang-Wen
Powiązania:
https://bibliotekanauki.pl/articles/2049419.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
high-carbon steel
critical conditions
dynamic recrystallization
work-hardening
kinetics model
Opis:
A hot compression test was conducted on a Gleeble-3500 thermo-simulation machine to study the critical conditions and kinetics of dynamic recrystallization in a high-carbon tool steel. The critical conditions for the initiation of dynamic recrystallization were determined using the working-hardening theory. The quantitative relationship between the critical characteristics of dynamic recrystallization and the hot deformation parameters were elucidated based on two different methods: the apparent method and physically based method. It was found that the two methods both have high applicability for the investigated steel, but the physically-based method needs less parameters and makes it possible to study the effect of different factors. A dynamic recrystallization kinetics model was used to calculate the recrystallization volume fraction under different conditions. The calculation results matched well with the data obtained from the flow curves.
Źródło:
Archives of Metallurgy and Materials; 2021, 66, 1; 119-125
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exposure to particulate matter 2.5 leading to lung microbiome disorder and the alleviation effect of Auricularia auricular-judae polysaccharide
Autorzy:
Zhang, Yanshu
He, Bin
Wu, Lei
Mi, Xiaoyi
Zhang, Lijin
Li, Shuang
Wang, Jian
Yu, Xiaoyu
Powiązania:
https://bibliotekanauki.pl/articles/2152971.pdf
Data publikacji:
2022
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
PM 2.5
inflammatory damage
lung injury
BALF
microbiome disorder
AAP
Opis:
Objectives The aim of the paper is to explore the role of lung microbiome disorder in lung tissue injury induced by exposure to particulate matter with a maximum diameter of 2.5 μm (PM2.5) and the alleviation effect of auricularia auricular-judae polysaccharide (AAP). Material and Methods Sprague Dawley rats were given PM2.5 suspension at a dose of 20 mg/l twice a week for 8 weeks. Then, 100 mg/kg or 200 mg/kg of AAP was administered to the rats after PM2.5 exposure. The bronchoalveolar lavage fluid (BALF) and lung tissue samples were collected at the end of the experiment. The BALF was meant to detect changes in lung microbiome by 16S sequences and cluster analysis, with the application of the principal component analysis and the partial least squares discriminant analysis. The levels of interferon-γ (IFN-γ), and interleukin (IL)-4, IL-8, and IL-10 in lung tissue were detected by the enzyme-linked immunosorbent assay method. The pathological changes in lung tissue were observed by hematoxylin and eosin staining. Results After PM2.5 exposure, the alveolar septum was widened, and the structures of alveolar walls were destroyed. There was inflammatory cells infiltration in the alveolar space and the interstitial space. Alpha diversity in BALF showed that the Chao1, ACE, Simpson, and Shannon values were increased, and the lung microbiome analysis revealed that the relative abundance of Firmicutes and Clostridium increased, while the relative abundance of Bacteroidetes and Akkermansia decreased. The contents of IFN-γ and IL-8 in lung tissue increased while the content of IL-10 decreased. After the administration of AAP, the alveolar structure damage was alleviated, and the interstitial hemorrhage, edema, and inflammatory cells infiltration were reduced. The Chao1 and ACE values decreased, and the taxonomic abundance values of Akkermansia were much higher. Simultaneously, the contents of IFN-γ, IL-4, and IL-8 decreased, and the content of IL-10 increased. Conclusions It was found that PM2.5 resulted in lung microbiome disorder, which might lead to the inflammation of lung tissue. It was also revealed that AAP could alleviate the inflammatory damage of lung tissue induced by PM2.5.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2022, 35, 6; 651-664
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Common mycelium networks with Paraglomus occultum induce better plant growth and signal substance changes between trifoliate orange seedlings
Autorzy:
Zhang, Y.-C.
Xie, M.-M.
Feng, H.-D.
Zhou, M.
Zhang, Z.Z.
Liu, C.-Y.
Wu, Q.-S.
Powiązania:
https://bibliotekanauki.pl/articles/11877054.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
Opis:
Mycorrhizal mycelium can simultaneously colonize two and more neighboring plants to form common mycelium network (CMNs), whereas the information regarding CMN effects on endogenous signal substances is limited. In this study, a rootbox was separated by 37- or 0.45-μm mesh to establish donor chamber (the presence of roots and hyphae) and receptor (hyphae presented or not, free of roots) chamber, where an arbuscular mycorrhizal (AM) fungus Paraglomus occultum was inoculated into trifoliate orange seedlings of donor chamber to illustrate the underground communications of signal substances by CMNs. Mycorrhizal colonization resulted in better plant growth performance and greater root morphology in donor and receptor plants. AM inoculation increased significantly the root nitric oxide (NO) and calmodulin (CaM) levels of donor plants, regardless of 37- and 0.45-μm mesh, and subsequent CMNs induced higher root NO and CaM levels in receptor plants. Mycorrhizal colonization did not produce significant changes in root zeatin riboside (ZR) levels of donor plants, but CMN hyphae modulated lower root ZR levels of receptor plants. Mycorrhizal inoculation and subsequent CMN hyphae induced lower root gibberellin levels of donor and receptor plants, and only CMN hyphae produced lower root methyl jasmonate concentrations of receptor plants. Our results first reveal the underground communication of CaM, NO, and ZR by CMNs with P. occultum between trifoliate orange seedlings.
Źródło:
Acta Scientiarum Polonorum. Hortorum Cultus; 2018, 17, 6; 95-104
1644-0692
Pojawia się w:
Acta Scientiarum Polonorum. Hortorum Cultus
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Experimental and optimization design of offshore drilling seal
Autorzy:
Zhang, Y.
Zhang, X.
Chang, X.
Wu, Q.
Powiązania:
https://bibliotekanauki.pl/articles/260627.pdf
Data publikacji:
2017
Wydawca:
Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Tematy:
offshore drilling
design optimization
seals
finite element analysis
MATLAB
Opis:
Three-cone bit is the key equipment in the exploration of the oil in offshore drilling and exploration, the bearing system and the seal system are the critical components for the bit. Especially in the offshore drilling environment, the seal design need to be carefully considered. A multi-objective optimization design including orthogonal design method and F-test with finite element analysis for a three-cone bit seal is proposed. Firstly, the calculation method of optimization targets are given, including the minimization of maximum contact pressure and leakage rate analyzed by ANSYS and MATLAB respectively, to maximize seal life and reliability. Then, an orthogonal experiment approach is used to investigate the effects of the eleven parameters on the seal performance, and the influence degrees of the seal factors on the optimization targets have been confirmed by F-test, and the reasonable factors can be determined by the trend of the targets. Finally, in order to validate the analysis results, a new seal was designed and tested on a seal tester compared to the previous seal. In this test, the seal maximum interface temperature that reflects the position of maximum contact pressure can be obtained by using three high precision thermocouples. Both the experiment results and the numerical analyses proved that the maximum contact pressure and leakage rate of the improved seal have been reduced compared to the previous.
Źródło:
Polish Maritime Research; 2017, S 3; 72-78
1233-2585
Pojawia się w:
Polish Maritime Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Concave and convex effects of ESG performance on corporate sustainable development: Evidence from China
Autorzy:
Zhang, XueHui
Miao, Le
Mu, Guoying
Wu, Kun-Shan
Powiązania:
https://bibliotekanauki.pl/articles/39992737.pdf
Data publikacji:
2024
Wydawca:
Instytut Badań Gospodarczych
Tematy:
ESG
corporate sustainable development
quantile regression
double-edged effect
Opis:
Research background: Corporate sustainable development (CSD) is essential to a company's success and survival. Environmental, social, and governance (ESG) are regarded as major factors in measuring the impact of CSD. Companies that perform well in terms of ESG can maintain a competitive advantage and achieve sustainable development. Poor management of ESG performance and involvement in controversial activity can harm a company's credibility and reputation in the market, as well as negatively impact sustainable development. Purpose of the article: Drawing on the stakeholder and signaling theories, this paper investigates the curvilinear nexus between ESG performance and CSD. Methods: Empirical studies were conducted on a sample of 697 Chinese listed manufacturing firms that disclosed ESG information from 2010 to 2020, with a total of 5699 firm-year observations. Quantile regression analysis and the U-test were used to examine the curvilinear ESG-CSD relationship. This technique was supplemented by conducting instrumental variables tests and propensity score matching to address concerns relating to the potential existence of endogeneity problems. Findings & value added: The results of the quantile regression estimation confirm the concave-convex (inverted U-shaped and U-shaped) ESG-CSD relationship via the U-test. The relationships between the environmental and social components and CSD follow an inverted U-shaped or half-inverted U-shaped pattern, while the relationship between the governance component and CSD exhibits a concave-convex pattern. A concave ESG-CSD nexus is evident in environmentally sensitive industries, whereas a half concave-convex ESG-CSD nexus is confirmed in non-environmentally sensitive industries. This study improves scholars’ understanding of ESG performance and provides a comprehensive perspective on the double-edged effects (positive and negative consequences) of ESG practices. The instrumentalization of ESG practices for management to seek personal gain has a negative impact on CSD, while ESG practices that add value for stakeholders have a positive impact. These findings provide empirical evidence for Chinese publicly listed manufacturing firms to effectively conduct ESG practices.
Źródło:
Oeconomia Copernicana; 2024, 15, 2; 595-636
2083-1277
Pojawia się w:
Oeconomia Copernicana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Usefulness of nonlinear interpolation and particle filter in Zigbee indoor positioning
Wykorzystanie nieliniowej interpolacji oraz filtru cząsteczkowego w pozycjonowaniu wewnątrz pomieszczeń przy użyciu technologii Zigbee
Autorzy:
Zhang, X.
Guo, H.
Wu, H.
Uradziński, M.
Powiązania:
https://bibliotekanauki.pl/articles/145368.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
technologia ZigBee
kalibracja obszaru lokalizacji
algorytm pozycjonowania
fingerprint positioning algorithm
RSSI
ZigBee sensor networks
polynomial interpolation
particle filter
Opis:
The key to fingerprint positioning algorithm is establishing effective fingerprint information database based on different reference nodes of received signal strength indicator (RSSI). Traditional method is to set the location area calibration multiple information sampling points, and collection of a large number sample data what is very time consuming. With Zigbee sensor networks as platform, considering the influence of positioning signal interference, we proposed an improved algorithm of getting virtual database based on polynomial interpolation, while the pre-estimated result was disposed by particle filter. Experimental result shows that this method can generate a quick, simple fine-grained localization information database, and improve the positioning accuracy at the same time.
Kluczem do algorytmu pozycjonowania wykorzystującego metodę fingerprinting jest ustanowienie skutecznej bazy danych na podstawie informacji z radiowych nadajników referencyjnych przy wykorzystaniu wskaźnika mocy odbieranego sygnału (RSSI). Tradycyjna metoda oparta jest na przeprowadzeniu kalibracji obszaru lokalizacji na podstawie wielu punktów pomiarowych i otrzymaniu dużej liczby próbek, co jest bardzo czasochłonne.
Źródło:
Geodesy and Cartography; 2014, 63, 2; 219-233
2080-6736
2300-2581
Pojawia się w:
Geodesy and Cartography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mathematical Model of Embedded Temperature Sensing Fabric Heat Transmission
Matematyczny model przepływu ciepła w tkaninie z umieszczonym w niej czujniku temperatury
Autorzy:
Zhang, R.
Deng, N.
Cheng, B.
Zhang, S.
Wu, Y.
Powiązania:
https://bibliotekanauki.pl/articles/949451.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
temperature sensing fabric
mathematical model
surface contact thermal resistance
testing system
temperature value
tkanina
czujnik temperatury
model matematyczny
oporność termiczna
system testowania
wartość temperatury
Opis:
In order to explore effect factors in the measurement of temperature sensing fabric, a heat transmission mathematical model of temperature sensing fabric was established. The concept of surface contact thermal resistance associated with the material thermal conductivity, fabric layer number and yarn linear density between the fabric and sensor was proposed in the model, whose surface contact thermal resistance was produced in the process of fabric heat transmission. Some test samples were woven to prove the rationality of the model. The results demonstrated that the value measured would be influenced by the performances of surface contact thermal resistance, which was consistent with the derivation of the theoretical model. The raw material, fabric layer number and yarn linear density of temperature sensing fabric had a great effect on the measurement value. The correlation coefficient reached more than 0.988 among the experimental and theoretical values, respectively, which proved that the heat transmission mathematical model of temperature sensing fabric could be applied in the research of this fabric.
Opracowano matematyczny model przepływu ciepła przez tkaninę zawierającą wbudowane czujniki temperatury w celu określenia wpływu poszczególnych czynników na przebieg pomiarów. Brano pod uwagę oporność termiczną styku czujników z tkaniną związaną z przewodnością termiczną materiału, ilość warstw i masę liniową przędz w obrębie tkaniny i czujników. Uzyskane współczynniki korelacji pomiędzy wartościami eksperymentalnymi i teoretycznymi przekraczały 0,988 co potwierdza, że opracowany przez nas matematyczny model przepływu ciepła w tkaninie pomiarowej można zastosować w tego typu badaniach.
Źródło:
Fibres & Textiles in Eastern Europe; 2016, 5 (119); 73-79
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Method of Structure Design and Heat Treatment of an Integrated Consolidation Sensor and Embedded Temperature Sensing Fabric
Metoda projektowania struktury zintegrowanego czujnika temperatury wbudowanego w tkaninę
Autorzy:
Zhang, R.
Deng, N.
Cheng, B.
Wu, Y.
Powiązania:
https://bibliotekanauki.pl/articles/949452.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
temperature sensing fabric
structure design
partial heat treatment
fabric testing
temperature value
tkanina
czujnik temperatury
częściowa obróbka cieplna
testy tkanin
wartość temperatury
Opis:
In order to solve the problem of temperature sensors easily slipping and improve the precision of temperature measurement in temperature sensing fabric, a specially designed fabric was developed. In this paper, the fabric comprised plain and multi-layered fabric. Sensors were embedded into the multi-layered fabric. The multi-layered fabric was treated by partial heat treatment to make the temperature sensors be fixed to the fabric. The temperature sensing fabrics were measured before and after the partial heat treatment. The results showed that during the heat treatment, the number of fabric layers and fabric organization had an effect on temperature measurement, and the values measured after partial heat treatment were closer to the true value than without treatment. In addition, with an increase in the number of fabric layesr, the values measured were closer to the real value. And the measurement results were closer to the true value when the multi-layered fabric’s organizational structure was plain.
Dla uzyskania hybrydowego elementu pomiarowego opracowano taką strukturę tkaniny aby móc umieścić w niej czujniki temperatury. Wielowarstwową tkaninę poddano odpowiedniej obróbce termicznej umożliwiającej zamocowanie czujników w tkaninie. Stwierdzono, że ilość warstw tkaniny i ich rozmieszczenie ma wyraźny wpływ na uzyskiwaną dokładność pomiaru temperatury. Przy zwiększeniu ilości warstw wzrastała dokładność pomiaru.
Źródło:
Fibres & Textiles in Eastern Europe; 2016, 5 (119); 68-72
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
COMBINATION OF BERBERINE AND MATRINE AFFECTS APOPTOSIS AND CELLCYCLE IN HUMAN CERVICAL CANCER CELLS
Autorzy:
Zhang, Qijiayu
Sun, Yi
Huang, Yuxi
Sun, Jing
Zhao, Chongbo
Song, Yijun
Wu, Juanhua
Powiązania:
https://bibliotekanauki.pl/articles/895719.pdf
Data publikacji:
2019-12-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
apoptosis
cervical cancer
Matrine
berberine
Opis:
Cervical cancer is the fourth leading cause of malignancy-related mortality in women worldwide, and effective advanced-stage therapies are urgently required. Berberine is a quaternary ammonium compound extracted from traditional Chinese medicinal herbs, including Phellodendron spp., with antibacterial and antitumor activities. Matrine, the main active ingredient of Sophora flavescens rhizomes, has not only traditionally described health effects but is also widely used for its anticancer, anti-inflammatory, immunoregulatory, antiviral, and hepatoprotective effects. We investigated the antitumor activities of berberine and matrine against human cervical cancer HeLa and SiHa cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, along with flow cytometry and western blotting analyses, to assess the effect of the compounds on the cellular status and apoptosis- and cell cycle-related proteins. The 24 h half-maximal inhibitory concentrations (IC50) of berberine and matrine were 123.633 ± 4.278 µmol/L and 9.625 ± 0.245 mmol/L against HeLa cells and 105.067 ± 3.745 µmol/L and 8.50 ± 0.23 mmol/L against SiHa cells, respectively. Berberine plus matrine inhibited cancer cell growth and caused cell cycle arrest. We observed an increased stimulation of apoptosis, which was likely mediated by enhanced levels of caspase-3, caspase-9, and B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax), as well as decreased Bcl-2 protein expression. Cell cycle arrest in the G1 phase was probably mediated by p21 upregulation and cyclin-dependent kinase (Cdk)-4, Cdk-6, and cyclin D1 suppression. Combination treatment with berberine and matrine effectively inhibited human cervical cancer cell proliferation, most likely by stimulating apoptosis and inducing cell cycle arrest.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1089-1097
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dissolution kinetics of hemimorphite in methane sulfonic acid
Autorzy:
Zhang, Qian
Wen, Shuming
Feng, Qicheng
Nie, Wenlin
Wu, Dandan
Powiązania:
https://bibliotekanauki.pl/articles/110482.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
hemimorphite
methane sulfonic acid
dissolution
kinetics
Opis:
Hemimorphite has a large content of zinc, but its recovery using flotation alone is low. Nowadays, hydrometallurgical and pyrometallurgical methods are used to treat zinc ores. In this work, the leaching and dissolution kinetics of hemimorphite by using methane sulfonic acid (MSA) as an alternative leaching reagent was investigated. The effects of several experimental parameters including reaction temperature, MSA concentration, particle size, and stirring speed were also analyzed. Results showed that zinc leaching increased with increased reaction temperature, MSA concentration, and stirring speed, as well as decreased particle size. The mechanism of hemimorphite dissolution in MSA solutions may be a new variant of the shrinking-core model. Based on experimental data and kinetics, the apparent activation energy was determined to be 49.50 kJ/mol. The rate of reaction equation was also obtained to describe the process and found that the MSA concentration largely influenced the leaching of hemimorphite.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 1; 1-9
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A fault diagnosis method for substation grounding grid based on the square-wave frequency domain model
Autorzy:
Zhang, P.-H.
He, J.-J.
Zhang, D.-D.
Wu, L.-M.
Powiązania:
https://bibliotekanauki.pl/articles/221635.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
square-wave
frequency characteristics
grounding grid
fault diagnosis
Opis:
Current methods of fault diagnosis for the grounding grid using DC or AC are limited in accuracy and cannot be used to identify the locations of the faults. In this study, a new method of fault diagnosis for substation grounding grids is proposed using a square-wave. A frequency model of the grounding system is constructed by analyzing the frequency characteristics of the soil and the grounding conductors into which two different frequency square-wave sources are injected. By analyzing and comparing the corresponding information of the surface potentials of the output signals, the faults of the grounding grid can be diagnosed and located. Our method is verified by software simulation, scale model experiments and field experiments.
Źródło:
Metrology and Measurement Systems; 2012, 19, 1; 63-71
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 89

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