Autor: Zawadzińska, Karolina - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Nitrosubstituted analogs of isoxazolines and isoxazolidines: a surprising estimation of their biological activity via molecular docking
Autorzy:: Zawadzińska, Karolina
Gostyński, Bartłomiej
Powiązania:: https://bibliotekanauki.pl/articles/35126576.pdf
Data publikacji:: 2023
Wydawca:: Radomskie Towarzystwo Naukowe
Tematy:: isoxazolines
isoxazolidines
molecular docking
molecular dynamics
biological activity
izoksazoliny
izoksazolidyny
dokowanie molekularne
dynamika molekularna
aktywność biologiczna
Opis:: The biological activities in the field of antimicrobial application of trihalomethylated isoxazolines and isoxazolidines were investigated by means of molecular docking. In our work, we compared these two groups of heterocyclic compounds due to their strength of non-covalent binding affinity with several exemplary proteins that are known to partake in various biological processes. The obtained results show that the investigated compounds possess higher binding affinities to selected proteins than many hitherto known and applied compounds.
Źródło:: Scientiae Radices; 2023, 2, 1; 25-46
2956-4808
Pojawia się w:: Scientiae Radices
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Preparation of conjugated nitroalkenes: short review
Autorzy:: Zawadzińska, Karolina
Gaurav, Gajendra Kumar
Jasiński, Radomir
Powiązania:: https://bibliotekanauki.pl/articles/35110314.pdf
Data publikacji:: 2022
Wydawca:: Radomskie Towarzystwo Naukowe
Tematy:: nitroalkenes
organic synthesis
nitrocompounds
nitroalkeny
synteza organiczna
nitrozwiązki
Opis:: Key protocols of the preparation of conjugated nitroalkenes were reviewed and critically discussed. It was established, that optimal strategy for the obtaining of target compounds are small molecules extrusion processes from saturated nitro-compounds. Among them, the most universal methodologies based on carboxylic acids elimination have been discussed, which provide for smooth applications.
Źródło:: Scientiae Radices; 2022, 1, 1; 69-83
2956-4808
Pojawia się w:: Scientiae Radices
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 3.

Tytuł:: Thermal [3+2] cycloaddition reactions as most universal way for the effective preparation of five-membered nitrogen containing heterocycles
Autorzy:: Kras, Jowita
Sadowski, Mikołaj
Zawadzińska, Karolina
Nagatsky, Roman
Woliński, Przemysław
Kula, Karolina
Łapczuk, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/35141032.pdf
Data publikacji:: 2023
Wydawca:: Radomskie Towarzystwo Naukowe
Tematy:: [3+2] cycloaddition
five-membered heterocycles
regioselectivity
stereoselectivity
[3+2] cykloaddycja
heterocykle pięcioczłonowe
regioselektywność
stereoselektywność
Opis:: The possibility of the construction of five-membered heterocycles, including single heteroatom or systems with two, three and four heteroatoms were critically reviewed based on the recent reports regarding to the [3+2] cycloaddition reactions. Almost all of analysed reaction are realized with high regio- and stereoselectivity.
Źródło:: Scientiae Radices; 2023, 2, 3; 247-267
2956-4808
Pojawia się w:: Scientiae Radices
Dostawca treści:: Biblioteka Nauki

Artykuł

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