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Wyszukujesz frazę "Zając, Dorota" wg kryterium: Autor


Tytuł:
Ibis Owidiusza − analiza literacka poematu
Ovid’s Ibis − a Literary Analysis
Autorzy:
Zając, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/2119784.pdf
Data publikacji:
1992
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Opis:
The poem, written in exile, is among Ovid’s less well-known works. Following, as indicated by the writer himself, the literary tradition of invective pieces in the style of Archilochus and a lost poem of the same title by Callimachus, Ibis comprises several hundred verses of mythological malediction against the poet’s enemy in Rome. The piece, composed into a brace structure in accordance with the rules of rhetoric, consists of several distinct thematic units. The largest part (more than half of the poem) contains sequences of curses linked only by mental association. Ovid makes ample use of rhetorical devices. As in his earlier works, also in Ibis he plays with words, constructing ever more complex variations. The poem, different as it is from Ovid’s all other output, is an intriguing piece of writing. It is possible to read it as a parody an uncommon form of consolation in disguise.
Źródło:
Roczniki Humanistyczne; 1992, 39-40, 3; 47-71
0035-7707
Pojawia się w:
Roczniki Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wykorzystanie testów genetycznych w postępowaniach o ustalenie ojcostwa
Use of DNA tests in cases of determining legal paternity
Autorzy:
Krekora-Zając, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1373965.pdf
Data publikacji:
2014
Wydawca:
Centralne Laboratorium Kryminalistyczne Policji
Tematy:
pochodzenie
ojcostwo
DNA
testy genetyczne,
postępowanie sądowe
descent
paternity
genetic tests
judicial procedure
Opis:
Przedmiotem opracowania jest analiza wpływu dostępności testów genetycznych na ustalenie pochodzenia dziecka od ojca. Niewątpliwie testy genetyczne ustalające pokrewieństwo stały się jednym z najczęściej komercyjnie wykonywanymi testami genetycznymi. Są one przeprowadzane zarówno indywidualnie jak również dla postępowań sądowych. Niewątpliwie powszechność stosowania testów genetycznym w celu wykluczenia pokrewieństwa stało się bardzo częstą praktyką sądową. Ponadto jak się wydaje właśnie z uwagi na fakt, że testy genetyczny dają niemalże pewność w zakresie ustalania pokrewieństwa zmieniono również regulacja kodeksu rodzinnego i opiekuńczego opierając stosunek ojcostwa na pewności co do pokrewieństwa genetycznego. Analizie poddano zarówno regulacje kodeksu rodzinnego i opiekuńczego jak również orzeczenia sądowe w celu wskazania charakteru dowodu z testów genetycznych oraz jego wpływu na ustalenie ojcostwa.
The objective of the study involves testing the influence of accessibility of DNA tests, on paternity determination. Without doubt, DNA tests determining the family relationship have become one of the most frequently performed genetic tests commercially. They are carried out both at individual request, as well as for use in judicial proceedings. Undoubtedly, the common use of DNA tests to exclude consanguinity has become very popular in judicial practice. Moreover, it seems that due to the fact that DNA tests are quite accurate in determining blood relations, the regulations of the Family and Guardianship Code have been changed in order to base paternity on the certainty of genetic relation. The study also involved the regulations of the Family and Guardianship Code as well as judicial decisions in order to indicate the nature of evidence from genetic testing and its impact on paternity recognition.
Źródło:
Problemy Kryminalistyki; 2014, 286; 43-47
0552-2153
Pojawia się w:
Problemy Kryminalistyki
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Physician scientist: clash of patient rights and principles of conducting research
Autorzy:
Krekora-Zając, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/48547686.pdf
Data publikacji:
2023-06-22
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
doctor’s responsibility
patient rights
biobank
research on human biological material
consent
freedom of science
trust
Opis:
Conducting scientific research, learning about the etiology of diseases, and searching for new methods of treatment are undoubtedly the basis of medicine. For centuries, a doctor has been a person who not only treated people, but also conducted scientific research aimed at deepening the knowledge about man. Due to the development of genetics, the pharmaceutical industry, and biobanks, this research has become mass and sometimes it is only human biological samples that are sufficient to carry it out. All this, undoubtedly, enables faster development of science, but puts a doctor in an extremely difficult situation of playing two roles, i.e. treating the patient and conducting scientific research using one’s biological material. In medical law, it has been emphasized for years that the basis of the relationship between a doctor and a patient is a special type of trust, which is systemically protected both by national and international legislature. The doctor is, therefore, obliged to act for the benefit of the patient. There is no doubt, however, that when conducting scientific research, a doctor sometimes faces the rivalry of patient rights, including the right to privacy and the right to freedom to conduct research. Both European and national lawmakers seem to notice these problems only partially, and only partially regulate the issue in question in both medical and personal data protection law. The subject of the reported research was analysis of the European and Polish law in terms of determining the extent to which this conflict of interests affects the patient’s rights and the doctor’s duties. In addition, the subject of analysis was to determine whether the person who gave a biological sample to the doctor to conduct research on it is always a patient and what consequences for the doctor’s legal liability this research on human biological samples has.
Źródło:
Studia Iuridica; 2022, 95; 241-263
0137-4346
Pojawia się w:
Studia Iuridica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ludzka próbka biologiczna wykorzystywana dla celów naukowych jako przedmiot prawa cywilnego
Autorzy:
Krekora-Zając, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1788188.pdf
Data publikacji:
2015-09-01
Wydawca:
Polska Akademia Nauk. Instytut Nauk Prawnych PAN
Tematy:
pobieranie narządów
bioetyka
eksperyment naukowy
prawo cywilne
organ donation
bioethics
scientific experiment
civil law
Opis:
The article is concerning analysis of legal status of human biological samples used in research purposes. Historical evolution of human body status, possible use of human biological samples and legal status of human biological samples under the European Community, Polish, Italian Law has been described in the article, as well as regulation in the Common Law countries. In author’s opinion the human biological samples should be recognized as a res for the legal purposes. Aforementioned approach provides the best protection of interests of both donors and biobanks. Paper contains conclusions de lege lata and de lege ferenda, including proposals of future legislation regarding biobanks and potential influence of foreign courts judicial decisions in this area on Polish legal practice.
Źródło:
Studia Prawnicze; 2015, 3 (203); 91-136
0039-3312
2719-4302
Pojawia się w:
Studia Prawnicze
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prawo do poznania matki biologicznej według krajowego prawa rodzinnego
Autorzy:
Krekora-Zając, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1788212.pdf
Data publikacji:
2014-09-01
Wydawca:
Polska Akademia Nauk. Instytut Nauk Prawnych PAN
Tematy:
birth mother
United Kingdom
family law
foreign country
parents
child
legal regulations
rights
maternity
right to privacy
comparative law
Italy
komparatystyka
matka biologiczna
Włochy
prawo rodzinne
Wielka Brytania
rodzice
państwa obce
regulacje prawne
dziecko
macierzyństwo
uprawnienia
przysposobienie
prawo do prywatności
Opis:
The subject of this article is an analysis whether on the grounds of Polish Code on Family and Guardianship it is possible to determine the one's right to recognize his/her mother. Introduction to the Polish Code on Family and Guardianship a legal definition of mother and claims for establish or denial of one's motherhood was legislator's attempt to regulate the civil status of child. Development of the in vitro treatment may lead to situation where one women would be donor of a germ cells while other women would bear a child. The article therefore provides an analysis of legal consequences of this amendment to the code in respect to legal regulation on motherhood. In particularly the issues of admissibility of claims for recognize one's genetic and biological mother as well as evidence limitation in this kind of cases would be addressed in the article.
Źródło:
Studia Prawnicze; 2014, 1 (197); 129-154
0039-3312
2719-4302
Pojawia się w:
Studia Prawnicze
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przygotowanie i badanie warstw organicznych dla zastosowań fotowoltaicznych
Autorzy:
Przybylski, Dariusz
Zając, Dorota
Patela, Sergiusz
Powiązania:
https://bibliotekanauki.pl/articles/304517.pdf
Data publikacji:
2019
Wydawca:
Wydawnictwo Druk-Art
Tematy:
warstwa organiczna
fotowoltaika organiczna
transmitancja
organic layer
organic solar farm
transmittance
Opis:
W artykule przedstawiono proces otrzymywania cienkich warstw organicznych. Nakładanie warstw na podłoża szklane odbywało się metodą spin-coatingu. Podczas procesu modyfikowane były takie parametry, jak: stężenie związku, rodzaj zastosowanego rozpuszczalnika, prędkość wirowania, czas wirowania oraz ilość naniesionej substancji. Zbadano właściwości otrzymanych cienkich warstw organicznych. Pomiaru ich grubości dokonano za pomocą profilometru optycznego, a następnie wynik zweryfikowano na profilometrze mechanicznym. Następnie zmierzono charakterystykę transmitancji na spektrofotometrze. W rezultacie przeprowadzonych prac opracowano technologię nanoszenia 100 nm warstw organicznych na podłoże szklane.
Źródło:
Napędy i Sterowanie; 2019, 21, 2; 103-105
1507-7764
Pojawia się w:
Napędy i Sterowanie
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surfaceome of pathogenic yeasts, Candida parapsilosis and Candida tropicalis, revealed with the use of cell surface shaving method and shotgun proteomic approach
Autorzy:
Karkowska-Kuleta, Justyna
Zajac, Dorota
Bochenska, Oliwia
Kozik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1038923.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cell surface shaving
proteomics
fungal pathogens
cell wall
Candida
Opis:
In the course of infections caused by pathogenic yeasts from the genus Candida, the fungal cell surface is the first line of contact with the human host. As the surface-exposed proteins are the key players in these interactions, their identification can significantly contribute to discovering the mechanisms of pathogenesis of two emerging pathogens from this genus, C. parapsilosis and C. tropicalis. Therefore, the aim of the present study was to identify the cell wall-attached proteins of these two species with the use of cell surface shaving and a shotgun proteomic approach. Different morphological forms of C. parapsilosis and C. tropicalis cells obtained after growth under various conditions were subjected to this treatment. This allowed to indicate the most abundant cell surface proteins on the basis of the normalized spectral abundance factors. In case of yeast-like forms these were, among others, proteins similar to a chitinase, glyceraldehyde-3-phosphate dehydrogenase and an inducible acid phosphatase for C. parapsilosis, and a constitutive acid phosphatase, pyruvate decarboxylase and glyceraldehyde-3-phosphate dehydrogenase for C. tropicalis. In case of pseudohyphal forms, proteins similar to a cell surface mannoprotein Mp65, chitinase and glycosylphosphatidylinositol-anchored transglycosylase Crh11 were identified at the cell surface of C. parapsilosis. The Rbt1 cell wall protein, a hyphally regulated cell wall protein and proteins from agglutinin-like sequence protein family were found as the most abundant on C. tropicalis pseudohyphae. Apart from the abovementioned proteins, several additional covalently bound and atypical cell wall proteins were also identified. These results extend the current knowledge regarding the molecular basis of virulence of these two non-albicans Candida species.
Źródło:
Acta Biochimica Polonica; 2015, 62, 4; 807-819
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interaction of human fibronectin with Candida glabrata epithelial adhesin 6 (Epa6)
Autorzy:
Zajac, Dorota
Karkowska-Kuleta, Justyna
Bochenska, Oliwia
Rapala-Kozik, Maria
Kozik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1038757.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Candida glabrata
epithelial adhesins
fibronectin
surface plasmon resonance
Opis:
Adherence of pathogens to extracellular matrix proteins and host cells is one of the essential steps in the microbial colonization of the human organism. The adhesion of C. glabrata, i.e. the second major causative agent of human disseminated candidiases after C. albicans, to the host epithelium mainly engages specific fungal cell wall proteins - epithelial adhesins (Epa) - in particular, Epa1, Epa6 and Epa7. The aim of the present study was to identify the major Epa protein involved in the interactions with the human extracellular matrix protein - fibronectin - and to present the kinetic and thermodynamic characteristics of these interactions. A relatively novel gel-free approach, i.e. the "cell surface shaving" that consists in short treatment of fungal cells with trypsin was employed to identify the C. glabrata surfaceome. Epa6 was purified, and the isolated protein was characterized in terms of its affinity to human fibronectin using a microplate ligand-binding assay and surface plasmon resonance measurements. The dissociation constants for the binding of Epa6 to fibronectin were determined to range between 9.03 × 10-9 M and 7.22 × 10-8 M, depending on the method used (surface plasmon resonance measurements versus the microplate ligand-binding assay, respectively). The identified fungal pathogen-human host protein-protein interactions might become a potential target for novel anticandidal therapeutic approaches.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 417-426
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Binding of human plasminogen and high-molecular-mass kininogen by cell surface-exposed proteins of Candida parapsilosis
Autorzy:
Karkowska-Kuleta, Justyna
Zajac, Dorota
Bras, Grazyna
Bochenska, Oliwia
Rapala-Kozik, Maria
Kozik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1038573.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
candidiasis
cell wall proteins
fibrinolysis
contact system
Opis:
Pathogenic microbes can recruit to their cell surface human proteins that are components of important proteolytic cascades involved in coagulation, fibrinolysis and innate immune response. Once located at the bacterial or fungal surface, such deployed proteins might be utilized by pathogens to facilitate invasion and dissemination within the host organism by interfering with functionality of these systems or by exploiting specific activity of the bound enzymes. Aim of the study presented here was to characterize this phenomenon in Candida parapsilosis (Ashford) Langeron et Talice - an important causative agent of systemic fungal infections (candidiases and candidemias) in humans. We have investigated the interactions of fungal surface-exposed proteins with plasminogen (HPG) and high-molecular-mass kininogen (HK) - the crucial components of human fibrinolytic system and proinflammatory/procoagulant contact-activated kinin-forming system, respectively. After confirming ability of the fungal surface-exposed proteins to bind HPG and HK, four of them - two agglutinin-like sequence (Als) proteins CPAR2_404780 and CPAR2_404800, a heat shock protein Ssa2 and a moonlighting protein 6-phosphogluconate dehydrogenase 1 - were purified using ion-exchange chromatography, gel filtration and chromatofocusing. Then, their affinities to HPG and HK were characterized with surface plasmon resonance measurements. The determined dissociation constants for the investigated protein-protein complexes were within a 10-7 M order for the HPG binding and in a range of 10-8-10-9 M for the HK binding. Detailed characterization of adsorption of these two important plasma proteins on the fungal cell surface may help to increase our understanding of molecular mechanisms of C. parapsilosis-dependent candidiasis.
Źródło:
Acta Biochimica Polonica; 2017, 64, 3; 391-400
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterization of the interactions between human high-molecular-mass kininogen and cell wall proteins of pathogenic yeasts Candida tropicalis
Autorzy:
Karkowska-Kuleta, Justyna
Zajac, Dorota
Bras, Grazyna
Bochenska, Oliwia
Seweryn, Karolina
Kedracka-Krok, Sylwia
Jankowska, Urszula
Rapala-Kozik, Maria
Kozik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1038758.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
contact system
kinins
inflammation
candidiasis
cell wall proteins
adhesion
Opis:
Candida tropicalis is one of the most frequent causes of serious disseminated candidiasis in human patients infected by non-albicans Candida species, but still relatively little is known about its virulence mechanisms. In our current study, the interactions between the cell surface of this species and a multifunctional human protein - high-molecular-mass kininogen (HK), an important component of the plasma contact system involved in the development of the inflammatory state - were characterized at the molecular level. The quick release of biologically active kinins from candidal cell wall-adsorbed HK was presented and the HK-binding ability was assigned to several cell wall-associated proteins. The predicted hyphally regulated cell wall protein (Hyr) and some housekeeping enzymes exposed at the cell surface (known as "moonlighting proteins") were found to be the major HK binders. Accordingly, after purification of selected proteins, the dissociation constants of the complexes of HK with Hyr, enolase, and phosphoglycerate mutase were determined using surface plasmon resonance measurements, yielding the values of 2.20 × 10-7 M, 1.42 × 10-7 M, and 5.81 × 10-7 M, respectively. Therefore, in this work, for the first time, the interactions between C. tropicalis cell wall proteins and HK were characterized in molecular terms. Our findings may be useful for designing more effective prevention and treatment approaches against infections caused by this dangerous fungal pathogen.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 427-436
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Warunki dopuszczalności prowadzenia badań naukowych w biomedycynie. Biobanki: wyzwanie w czasach Big Data
Autorzy:
Dorota, Krekora-Zając,
Powiązania:
https://bibliotekanauki.pl/articles/902521.pdf
Data publikacji:
2018-06-22
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
biobanki
Opis:
-
Źródło:
Studia Iuridica; 2018, 73; 7-8
0137-4346
Pojawia się w:
Studia Iuridica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Conditions for the Admissibility of Scienti C Research in Biomedicine Biobanking: A Challenge in Times of Big Data
Autorzy:
Dorota, Krekora-Zając,
Powiązania:
https://bibliotekanauki.pl/articles/902562.pdf
Data publikacji:
2018-06-22
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
biobanks
donors
consent
biomedical research
information
human biological sample
personal data
GDPR
biobanki
dawcy
zgoda
badania biomedyczne
informacje
ludzka próbka biologiczna
dane osobowe
RODO
Opis:
The subject of the article is the analysis of the rights of donors donating their biological samples to biobanks in the 21st century. Issues regarding donor rights have been analyzed since the 1980s, however, changing times, creating Big Data databases as well as evolving legal awareness of donors meant that today the role of donors in the biobanking process should be perceived differently. Donors become active subjects of scientific research which is connected with the need to answer questions about the obligations to inform them about the results of scientific research conducted on their samples or incidental findings. Likewise, the combination of data registers and the creation of Big Data basis require the re-thinking of terms such as the protection of personal data of donors or the anonymisation of their data. These issues are imposed by negligence or complete lack of legal regulation of the biobanking, which makes the legal protection of the rights of donors dependent on the will of a particular biobank. All these phenomena result in the necessity of new approaches to the rights of donors and their inclusion in the future legal regulation.
Źródło:
Studia Iuridica; 2018, 73; 57-71
0137-4346
Pojawia się w:
Studia Iuridica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Locomotor activity of adult Dermacentor reticulatus ticks (Ixodida: Ixodidae) in natural conditions
Autorzy:
Buczek, Alicja
Zając, Zbigniew
Woźniak, Aneta
Kulina, Dorota
Bartosik, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/989880.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
dermacentor reticulatus
locomotor activity
host-seeking activity
tick aggressiveness
Opis:
Introduction and objective. Expansion into new areas and the great epidemiological significance of the D. reticulatus tick in Europe prompts investigations of its ethology. Therefore, the locomotor activity of D. reticulatus adult stages in an optimal habitat during the spring and autumn activity periods was analysed. Materials and method. Marked D. reticulatus adults were placed at the central point of each experimental plot. At regular time intervals, specimens attached to the cloth used in the flagging method were collected, and the distance covered by the ticks was measured. In each collection round, the temperature and humidity level in the habitat was also measured. Results. Within 7 weeks, adult D. reticulatus ticks can cover an average distance of 60.71±44 cm. The locomotor activity of adult stages is greater during the spring than the autumn activity period. Questing, females cover a greater distance (66.35±100 cm) than male ticks (54.85±45 cm). Adult stages are characterised by greater aggressiveness 24 hours after being released, i.e. 30% of females and 19% of males attempt to attach to host skin. The locomotor activity in adult ticks depends on the humidity of the habitat (Z=-1.198; p=0.050). The temperature does not affect tick walking. Conclusions. Given the low rates of horizontal locomotion of adult D. reticulatus ticks, the prevalence of the species in nature is determined by the presence of their hosts and humidity conditions ensuring their further development and survival. The dependence of D. reticulatus locomotor activity and aggressiveness on the humidity level implies an increased risk of host attacks in locations and periods that offer favourable humidity conditions for this species.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł

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