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Wyszukujesz frazę "Zadrag-Tecza, Renata" wg kryterium: Autor


Wyświetlanie 1-3 z 3
Tytuł:
The rules of aging: are they universal? Is the yeast model relevant for gerontology?
Autorzy:
Bilinski, Tomasz
Zadrag-Tecza, Renata
Powiązania:
https://bibliotekanauki.pl/articles/1039193.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
age related diseases
longevity
yeast
Opis:
The success of experimental biology was possible due to the use of model organisms. It is believed that the mechanisms of aging have a universal character and they are conserved in a wide range of organisms. The explanation of these universal mechanisms by tracing survival curves of model organisms clearly suggests that death of individuals is a direct consequence of aging. Furthermore, the use of unicellular organisms like yeast Saccharomyces cerevisiae to explain the aging processes of multicellular organisms runs the risk of oversimplification. Aging is a very complex process and therefore in this paper we present arguments suggesting that some of these fundamental assumptions require a deep rethinking and verification.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 663-669
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The links between hypertrophy, reproductive potential and longevity in the Saccharomyces cerevisiae yeast
Autorzy:
Molon, Mateusz
Zadrag-Tecza, Renata
Powiązania:
https://bibliotekanauki.pl/articles/1038822.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
yeast
lifespan
longevity
hypertrophy
Opis:
The yeast Saccharomyces cerevisiae has long been used as a model organism for studying the basic mechanisms of aging. However, the main problem with the use of this unicellular fungus is the unit of "longevity". For all organisms, lifespan is expressed in units of time, while in the case of yeast it is defined by the number of daughter cells produced. Additionally, in yeast the phenotypic effects of mutations often show a clear dependence on the genetic background, suggesting the need for an analysis of strains representing different genetic backgrounds. Our results confirm the data presented in earlier papers that the reproductive potential is strongly associated with an increase in cell volume per generation. An excessive cell volume results in the loss of reproductive capacity. These data clearly support the hypertrophy hypothesis. The time of life of all analysed mutants, with the exception of sch9D, is the same as in the case of the wild-type strain. Interestingly, the 121% increase of the fob1D mutant's reproductive potential compared to the sfp1D mutant does not result in prolongation of the mutant's time of life (total lifespan).
Źródło:
Acta Biochimica Polonica; 2016, 63, 2; 329-334
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential
Autorzy:
Zadrag-Tecza, Renata
Molon, Mateusz
Mamczur, Jan
Bilinski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1039620.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
lifespan
oxidative stress
yeast
Opis:
The lifespan of budding yeast cells is divided into two stages: reproductive and post-reproductive. The post-reproductive stage of the yeast's lifespan has never been characterized before. We have analyzed the influence of various mutations on the post-reproductive (PRLS) and replicative (RLS) lifespans. The results indicate that PRLS demonstrates an inverse relationship with RLS. The observed lack of differences in the total lifespan (TLS) (expressed in units of time) of strains differing up to five times in RLS (expressed in the number of daughters formed) suggests the necessity of revision of opinions concerning the use of yeast as a model organism of gerontology.
Źródło:
Acta Biochimica Polonica; 2013, 60, 1; 111-115
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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